Clinical trials: Radiology
Cardiovascular Disease
X-ray Dose Reduction Study for Endovascular Interventional Radiology
ClarityIQ is a novel X-ray imaging technology, that combines advanced real-time image noise reduction algorithms, with state-of-the-art hardware to reduce patient entrance dose significantly.
- Trial name
- NCT01599741
- Testing
- Low-dose DSA (83% reduction compared to normal dose) with novel X-ray imaging technology., Normal dose DSA with conventional X-ray imaging technology
- Where
- Netherlands
- Volunteers
- 51 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Periodontal Diseases, Dental Caries
A Comparison of the Accurate Diagnosis of the Horizontal & Vertical Bitewing Images
The aims of this research are to determine if vertical bitewings will be more effective and more comprehensive for the diagnosis of caries and the level of alveolar bone loss than the horizontal bitewing technique for the…
- Trial name
- NCT04341636
- Testing
- Bitewing X ray
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Diabetes Mellitus, Type 2
Study In Postmenopausal Women With Type 2 Diabetes Looking At Approved Diabetes Drugs And How They Affect Bone Health
The purpose of this study is to determine the effects of rosiglitazone on the bone in postmenopausal women with type 2 diabetes mellitus
- Trial name
- NCT00679939
- Testing
- Rosiglitazone, Metformin
- Where
- 42 sites in United States, Argentina and 6 more
- Volunteers
- 226 people
- Sponsor
- GlaxoSmithKline
Oral Cavity Squamous Cell Carcinoma
Helical CT, PET/CT, MRI, and CBCT Alone or in Combination in Predicting Jaw Invasion in Patients With Oral Cancer
This clinical trial studies how well helical computed tomography (CT), positron emission tomography (PET)/CT, magnetic resonance imaging (MRI), and cone beam computed tomography (CBCT) work alone or in combination in predicting…
- Trial name
- NCT03053960
- Testing
- Computed Tomography, Positron Emission Tomography and Computed Tomography Scan, Cone-Beam Computed Tomography
- Volunteers
- 8 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Glioblastoma, Gliosarcoma
A Study of ABT-414 in Participants With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification
This study seeks to determine whether the addition of ABT-414 to concomitant radiotherapy and temozolomide (TMZ) followed by combination of ABT-414 with adjuvant TMZ prolongs overall survival (OS) among participants with newly…
- Trial name
- Intellance1 (NCT02573324)
- Testing
- Temozolomide, Depatuxizumab mafodotin, Radiation
- Where
- 212 sites in United States, Argentina and 26 more
- Volunteers
- 691 people
- Sponsor
- AbbVie
Osteoarthritis
A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee
The objective of this 2-year study is to evaluate the safety, tolerability and disease modifying efficacy of SD 6010, an inhibitor of inducible nitric oxide synthase (iNOS), in overweight and obese subjects with knee…
- Trial name
- ITIC (NCT00565812)
- Testing
- SD-6010
- Where
- 183 sites in United States, Argentina and 12 more
- Volunteers
- 1,457 people
- Sponsor
- Pfizer
Anxiety
Patient Anxiety During Radiological Examination
This clinical trial design evaluates whether hand massage reduces anxiety levels in cancer patients as they undergo radiological examination to evaluate tumor response.
- Trial name
- NCT02496533
- Testing
- Hand Massage
- Volunteers
- 217 people
- Sponsor
- Midwestern Regional Medical Center
Arrhythmias, Cardiac
X-ray Dose Reduction in Electrophysiology
Allura Clarity is a novel X-ray imaging technology, that combines advanced real-time image noise reduction algorithms, with state-of-the-art hardware to reduce patient entrance dose significantly.
- Trial name
- NCT01593852
- Testing
- Advanced image processing, Regular image processing
- Where
- Netherlands
- Volunteers
- 136 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Radial Artery Incision Site Closure
Transradial-Band Pilot Study
In the study group, the TR-Band will be in left in place for 15 minutes before it is gradually deflated by 25% at 15 minute intervals.
- Trial name
- NCT04709341
- Testing
- TR Band 60MIN, TR Band 120MIN
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Acute Coronary Syndrome
Rapid Assessment of Potential Ischaemic Heart Disease With CTCA
This study aims to investigate the effect of early CTCA in patients with suspected or confirmed Acute Coronary Syndrome (ACS) presenting to the Emergency Department (ED) or Medical Assessment Unit (MAU), upon interventions, event…
- Trial name
- RAPID-CTCA (NCT02284191)
- Testing
- CT Coronary Angiogram
- Where
- 37 sites in Jersey, United Kingdom
- Volunteers
- 1,749 people
- Sponsor
- University of Edinburgh
MRI
MRI Assessing Clinical Usability of STrategically Acquired Gradient Echo on Human Participants
The study's purpose is to validate STAGE images and, when applicable, their equivalence to conventional MRI through an assessment by a trained certified neuroradiologist in a clinical setting.
- Trial name
- STAGE (NCT04292301)
- Testing
- STrategically Acquired Gradient Echo (STAGE)
- Where
- 5 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- SpinTech, Inc.
Dental Caries
Conventional Bite Wing Radiography Versus Stationary Intraoral Tomosynthesis, a Comparison Study
A comparison of caries detection rates between conventional intraoral bitewing radiography and a stationary intraoral digital tomosynthesis (s-IOT) using a carbon nanotube X-ray source array.
- Trial name
- NCT02873585
- Testing
- Stationary intraoral tomosynthesis, Standard conventional bitewing radiography
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Revision, Joint
Evaluation of the Trabecular Metal™ Revision Hip Cup Using Bone Mineral Density (DEXA)
In 1997, the FDA approved the use of Trabecular Metal™ (Zimmer, Trabecular Metal Technology, Inc., Parsippany, NJ) for acetabular cups, a porous tantalum structural biomaterial that was developed to address the limitations of…
- Trial name
- NCT01183260
- Testing
- Trabecular Metal Revision Cup, Trabecular Metal Modular Cup
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The Cleveland Clinic
Occupational Exposure to Radiation
New Fabric Attenuation Device in Endovascular Interventional Radiology II (PREFER II)
The PREFER II trial primary objective of the trial is to show how much radiation attenuation is provided by XPF thyroid collars in absolute and relative terms.
- Trial name
- PREFER-II (NCT01611454)
- Testing
- XPF thyroid collar, Standard 0.5mm lead equivalent thyroid collar
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Baptist Health South Florida
Abdominal Pain, Pelvic Pain
POCUS Assessment of Bladder Fullness for Girls Awaiting Radiology-Performed Transabdominal Pelvic Ultrasound
The purpose of this study is to assess the accuracy and utility of point-of-care ultrasound (POCUS) of the bladder compared to patient's sensation of bladder fullness in predicting the ability to successfully perform a…
- Trial name
- NCT02923245
- Testing
- point-of-care ultrasound
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Lifespan
Total Hip Replacement
Evaluation of X-ray, Acetabular Guides and CT in THR
Total hip replacement is one of the most successful surgical procedures of modern times, with over 80,000 performed each year in the UK.
- Trial name
- EXACT (NCT03072706)
- Testing
- Corin OPS™, 2D X-ray templating technology
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Total Knee Arthroplasty
Stereo Radiography of TKA Patella Mechanics
The overall purpose is to compare the kinematics and mechanics of medialized dome and anatomic resurfacing through measurement and simulation, and to correlate these findings with patient satisfaction and performance.
- Trial name
- NCT02532933
- Testing
- DePuy Synthes Attune PS RP
- Volunteers
- 44 people
- Sponsor
- University of Denver
Lymphangioleiomyomatosis
A Study to Determine the Safety and Effectiveness of RAD001 (Everolimus) in Patients With Lymphangioleiomyomatosis
This was an exploratory study to determine whether escalating doses of RAD001 (everolimus) were safe and effective in patients with Lymphangioleiomyomatosis
- Trial name
- NCT01059318
- Testing
- Everolimus
- Where
- 4 sites in United States, France and 1 more
- Volunteers
- 24 people
- Sponsor
- Novartis Pharmaceuticals
Cancer
Default Options to Reduce Unnecessary Daily Imaging During Palliative Radiation
The goal of this study is to reduce preference sensitive, unnecessary daily imaging during radiation treatment in which a pre-planned quality improvement default option for radiation treatment prescriptions will be introduced…
- Trial name
- NCT03110692
- Testing
- Default initiation
- Where
- United States
- Volunteers
- 1,188 people
- Sponsor
- University of Pennsylvania
Head and Neck Cancer
Phase III Xevinapant (Debio 1143) and Radiotherapy in Resected LA SCCHN, High Risk, Cisplatin-ineligible Participants (XRAY VISION)
The purpose of this study is to demonstrate the superior efficacy of Xevinapant (Debio 1143) versus placebo when added to radiotherapy in the treatment of high-risk participants with resected locally advanced squamous cell…
- Trial name
- NCT05386550
- Testing
- Xevinapant, IMRT
- Where
- 206 sites in United States, Argentina and 24 more
- Volunteers
- 166 people
- Sponsor
- EMD Serono Research & Development Institute, Inc.