Clinical trials: Raman Spectroscopy
Parkinson's Disease and Parkinsonism
Saliva and Extracellular Vesicles for Parkinson's Disease
Rehabilitation is crucial in the treatment of people with Parkinson's disease (PD) as it can ameliorate motor and non-motor impairments, improving their clinical profile and quality of life.
- Trial name
- RaSPiD (NCT05320250)
- Testing
- Single saliva collection, Saliva collection, longitudinal
- Where
- 4 sites in Italy
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Oral Cancer, Dysplasia
Real-time Molecular Diagnosis of Oral Precancer
The "Real-time molecular diagnosis of oral precancer" or the LIP study is testing a new device for the detection of cancer in the mouth. Oral cancers are serious and devastating illnesses, especially if detected at a late stage.
- Conditions
- Oral Cancer, Dysplasia, Oral Lesions, Oral Pre-cancer
- Trial name
- LIP (NCT07110623)
- Testing
- LIP device
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King's College London
Child Nutrition, Fruit and Vegetable Intake
Pink and Dude Chef
The purpose of the study is to evaluate an afterschool program to teach nutrition through basic cooking skills. This after school extracurricular program increases the students' confidence, knowledge, and skills for cooking as…
- Conditions
- Child Nutrition, Fruit and Vegetable Intake, Healthy Food Choice, Healthy Food Preparation
- Trial name
- NCT01803997
- Testing
- Pink and Dude Chef Afterschool Cooking Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Diabetes Mellitus
Clinical Validation of mμSORS for Non-invasive Blood Glucose Detection in Non-diabetic Subjects
This is a single-center, open-label, prospective study. Blood glucose is measured at different time points during oral glucose tolerance test and hypoglucose clamp test in healthy subjects, using both venous plasma and…
- Trial name
- NCT06512077
- Testing
- Multi-channel Microspatial Offset Raman Scattering Spectroscopy (mμSORS) for Noninvasive Blood Glucose Detection
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Lymphoma, Head and Neck Cancer
DOLPHIN-VIVO: Diagnosis Of LymPHoma IN Vivo (Ex Vivo Phase)
Lymphoma diagnosis often involves removal and biopsy of one or more lymph nodes. Many (around half) of these diagnostic procedures show that no cancer is present, hence unnecessary removal results in numerous side effects and…
- Trial name
- DOLPHIN-VIVO (NCT04162431)
- Testing
- spectroscopic measurement, FNA biopsy, histopathology and cytology
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Endometriosis, Endometrioma
Raman Spectroscopy and Endometriosis
We aimed to use Raman spectroscopy to detect differences between healthy controls and patients with surgically proven endometriosis.
- Trial name
- NCT04015297
- Testing
- raman analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Diabetes Mellitus, Medical Device
Clinical Validation of mμSORS for Noninvasive Blood Glucose Detection
This is a single-center, open-label, prospective study. Blood glucose was measured at different time points during oral glucose tolerance testing in healthy subjects and patients with type 2 diabetes mellitus, using both venous…
- Trial name
- NCT05504005
- Testing
- Multi-channel Microspatial Offset Raman Scattering Spectroscopy (mμSORS) for Noninvasive Blood Glucose Detection
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Skin Physiology, Dermal Administration
Topical Application of Highly Concentrated Water-in-oil Emulsions
The purpose of this study is to I. determine the effect of repetitive application of newly developed silicone based formulations (placebo water-in-oil emulsions) on transepidermal water loss and other physiological skin…
- Conditions
- Skin Physiology, Dermal Administration, Emulsions
- Trial name
- NCT03876639
- Testing
- Application of emulsion, Measurement of physiological skin parameters, Tape stripping
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Diabetes
Clinical Diagnosis of Diabetes Using Surface-enhanced Raman Spectroscopy Liquid Biopsy and Machine Learning
This project aims to adapt the gold nanoparticle-based surface-enhanced Raman spectroscopy (SERS) technology to clinical application.
- Trial name
- NCT06862778
- Testing
- SERS
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University Hospital, Aachen
Lung Cancer
Analysis of P-Selectin Expression on Platelets of Blood From Lung Cancer Patients
Purpose: Selectins are vascular cell adhesion molecules involved in adhesive interactions of leukocytes and platelets and endothelium within the blood circulation.
- Trial name
- NCT02758678
- Testing
- A single 2 ml heparinised peripheral blood sample
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Science and Technology Park, Center of Innovation Technologies for Human Health
Typhoid Fever
Diagnosis and Staging of Typhoid Fever Using Surface-enhanced Raman Spectroscopy Liquid Biopsy
The goal of this project is to adapt the gold nanoparticle-based surface-enhanced Raman spectroscopy (SERS) technology to clinical application.
- Trial name
- NCT06546982
- Testing
- Surface-enhanced Raman Spectroscopy
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Aachen