Clinical trials: Randomised Clinical Trial
Sexual Functioning
The Impact of Mindful Compassion on Sexual Functioning Post Breast Cancer Treatment
Sexual dysfunction is commonly reported post cancer treatments. Sexual desire and body image are interrelated. Indeed, sexual wellbeing can be affected by diagnosis, medication and cancer treatments which can damage body tissues…
- Trial name
- NCT06046716
- Testing
- Mindful compassion based on behavioural change taxonomy experimental group
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- London Metropolitan University
Chronic Obstructive Pulmonary Disease, COPD
Clinical Trial Comparing the Pharmacological Effects of EP395 With Placebo in Healthy Adults
This study aims to assess the effect of EP395 against an induced inflammation of the lung. In addition, further data about the safety and tolerability of EP395 will be collected.
- Trial name
- NCT05516316
- Testing
- EP395
- Where
- Germany
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- EpiEndo Pharmaceuticals
Peripheral Arterial Disease
Exercise on Expression of Heat Shock Protein 70 in Arterial Risk
Introduction: Atherosclerotic Peripheral Arterial Disease (PAD) is the leading cause of mortality in the western world. To maintain homeostasis of the vessel wall, vascular cells produce a high level of heat shock proteins (HSP)…
- Trial name
- HSP70 (NCT04743128)
- Testing
- Exercise
- Where
- Mexico
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad Popular Autónoma del Estado de Puebla
Peri-Implantitis
Reconstructive Surgical Therapy of Peri-implantitis
Various treatment protocols of peri-implantitis involving surgical therapies with open flap debridement procedures, resective or reconstructive modalities have been documented to achieve variable success.
- Trial name
- NCT04769609
- Testing
- bioresorbable membrane
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Gazi University
Dentin Sensitivity
Propolis in Reducing Dentin Hypersensitivity
Objective: This randomized, double-blind, parallel, placebo-controlled clinical trial aims to evaluate the effect of propolis with two distinct concentrations (10% and 15%), and the impact on volunteers' quality of life.
- Trial name
- NCT05083052
- Testing
- Propolis 15%, Propolis 10%
- Where
- Brazil
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Primary Insomnia
Mindfulness and RelaxationTraining for Insomnia (MRTI) on Postmenopausal Women: a Randomized Clinical Trial.
Summary Introduction: Insomnia is a symptom of sleep disorders most prevalent. Primary insomnia, the investigators analyzed, often related to stress states acquired, generalized anxiety and stress, which are important factors…
- Trial name
- NCT01593436
- Testing
- mindfulness training
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cicatrix
Improvement in Scar Appearance Following Injection of Avotermin (Juvista) Into Skin Incisions Made in Healthy Men and Women
This is a single-centre, double-blind, Placebo-controlled, randomised trial. Trial subjects received four 1cm incisional wounds on the inner aspect of each upper arm (eight in total), giving four pairs of anatomically matched…
- Trial name
- NCT00629811
- Testing
- Avotermin (Juvista)
- Where
- United Kingdom
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Renovo
Back Pain, Back Disorder
Blinding Assessment of Manual Therapy Interventions of the Back in Swiss Graduate Students
There is marked uncertainty regarding the feasibility of achieving adequate blinding in randomized controlled trials of manual therapy.
- Conditions
- Back Pain, Back Disorder, Back Pain, Low
- Trial name
- NCT05822947
- Testing
- Active manual therapy, Control manual therapy
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cesar A Hincapié, DC PhD
Cesarean Section, Repeated, Cesarean, Uterine Scar Thickness
Evaluation of Cesarean Scar After Three Different Uterine Closure Technis
The study compares three techniques of uterine closure on myometrium thickness at the site of uterine scar of women who underwent repeated cesarean section.
- Conditions
- Cesarean Section, Repeated, Cesarean, Uterine Scar Thickness, Cesarean, Residual Myometrial Thickness
- Trial name
- NCT03915847
- Testing
- Single layer closure, Double layer closure, Doble layer closure with trimming
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Physical Activity
Effects of a Peer-led Walking In ScHools Intervention
Children and young people are recommended to undertake at least 60 minutes of moderate to vigorous intensity physical activity each day.
- Trial name
- WISH project (NCT02871830)
- Testing
- Physical Activity
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Malnutrition
Effects of Fortified Complementary Foods on Vitamin A Status and Body Pool Size in Ghanaian Infants.
This study tried to prove that children given food supplements containing vitamin A would have better liver vitamin A stores than children given food supplements without vitamin A over a 5 month period.
- Trial name
- vitapool (NCT01751009)
- Testing
- Vitamin A supplements, Sprinkles without Vitamin A
- Where
- Ghana
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Kintampo Health Research Centre, Ghana
Postoperative Pain
Postoperative Pain of Rotary Versus Reciprocating Motions of Two Single Files
An equivalent parallel randomized clinical trial was approved by the local University Committee of Ethics. 260 children with necrotic primary molars were allocated into 2 equal groups (82 children per group).
- Trial name
- NCT05059171
- Testing
- OneSahpe single file, WaveOne Gold single file
- Where
- Egypt
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Minia University
Low Anterior Resection Syndrome, Rectal Cancer
Comparison of Transanal Irrigation and Glycerol Suppositories in Treatment of Low Anterior Resection Syndrome
The study is a multicentre randomized controlled trial with the objective to compare the effect of transanal irrigation with glycerol suppositories in patients suffering from major Low Anterior Resection Syndrome (LARS).
- Trial name
- NCT04087421
- Testing
- Qufora Irrisedo Cone System, Glycerol "OBA"
- Where
- Denmark
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Quality of Life, Psychological Distress
Trial of Benefit Finding in Caregivers: The Building Resources in Caregivers (BRiC) Study
A randomised controlled trial that will compare the effects of a brief benefit -finding writing intervention with an active control condition on quality of life and psychological health among informal caregivers.
- Trial name
- BRiC (NCT02444312)
- Testing
- Benefit-finding Writing Activity, Neutral Writing Activity
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Airway Obstruction, Pain
Dental Isolation Systems Among Pediatric Patients With Different Airway Patency
This randomized clinical trial will aim to evaluate the effect of DryShield isolation (DSI) and Rubber Dam isolation (RDI) systems on arterial oxygen saturation (SpO2), heart rate (HR), blood pressure (BP), behavior, subjective…
- Conditions
- Airway Obstruction, Pain, Behavior
- Trial name
- NCT06128811
- Testing
- Rubber Dam Isolation, DryShieled isolation, fissure sealant
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Gingival Recession, Localized, Gingival Recession
Root Coverage With Tunneling Technique With Connective Tissue Versus Coronal Advancement Flap Technique.
This is a randomized triple-blind clinical trial. This comparative clinical study investigates the efficacy of root coverage using two periodontal techniques: the tunneling technique and the coronal advancement technique.
- Trial name
- NCT06228534
- Testing
- Root coverage with tunneling technique
- Where
- Ecuador
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Luis Alberto Chauca Bajaña
Fracture of Clavicle
Conservative Interventions for Treating Clavicle Fractures in Adults
Background: Fracture of the clavicle is common accounting for 2.6% to 4 % of all fractures, with an overall incidence of 36.5 to 64 per 100,000 per year. Around 80% of clavicle fractures occur in the middle third of the clavicle.
- Trial name
- NCT02398006
- Testing
- a standard arm sling, a figure-of-eight bandage
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Schizophrenia
A Safety，Tolerability and Pharmacokinetics Clinical Trial of JX11502MA Capsule
The purpose of this study is to investigate the safety, tolerability and pharmacokinetic characteristics of JX11502MA capsule on healthy human, and to explore the relationship between the dose, pharmacokinetic parameters and…
- Trial name
- NCT05233657
- Testing
- JX11502MA
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Zhejiang Jingxin Pharmaceutical Co., Ltd.
Polycystic Ovary Syndrome, Infertility
Letrozole vs Clomiphene Citrate for Induction of Ovulation in Women With Polycystic Ovarian Syndrome
It was randomised controlled study to compare the efficacy of clomiphene and letrozole in polycystic ovarian syndrome(PCOS) women with infertility.The aim was to select more appropriate treatment for ovulation induction in PCOS…
- Trial name
- NCT05702957
- Testing
- letrozole 2.5mg-7.5mg, Clomiphene Citrate 50mg-150mg
- Where
- Pakistan
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Cost Effectiveness
Clinical and Cost-effectiveness of Fluoride Varnish Versus Resin Based Sealant
The aim of the present study is determine the cost-effectiveness, clinical-effectiveness, acceptability and adverse effect of resin sealants versus the fluoride varnish for the prevention of dental caries on newly erupted…
- Trial name
- NCT04603573
- Testing
- fluoride varnish (3M Clinpro White Varnish 5% sodium fluoride ), Resin based fissure sealant (3M Clinpro sealant )
- Where
- Egypt
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Cairo University
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