Clinical trials: Randomised Clinical Trial
Preoperative Care
Preoperative Carbohydrate Loading in Patients Undergoing Day-case Cholecystectomy
Background: Preoperative carbohydrate loading has been shown to reduce preoperative discomfort and postoperative nausea and vomiting in general surgical patients.
- Trial name
- NCT03757208
- Testing
- carbohydrate rich drink
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Osteoporosis
Selenium for Musculoskeletal Health
This research aims to determine whether selenium supplements improve bone and muscle health in older women at risk of osteoporosis (low bone density or weak bones) and fracture (broken bones).
- Trial name
- NCT02832648
- Testing
- selenase (selenium)
- Where
- United Kingdom
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Cervical Cancers, Breast Cancer
Effectiveness and Impact of the Lived Experience Cancer Awareness Campaign on Screening Participation
This study will be conducted as a parallel-arm, open-label, randomized controlled trial (RCT) to evaluate the effectiveness and impact of the Lived Experience Communication Campaign (LECC) on cancer screening participation rates…
- Conditions
- Cervical Cancers, Breast Cancer, Oral Cancer
- Trial name
- NCT06874985
- Testing
- Lived experience video campaign
- Where
- India
- Volunteers
- 1,264 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Wound Heal
Comparing the Effectiveness of Cyanoacrylate Tissue Adhesives and Conventional Sutures
This study compares the effectiveness of two materials used for intraoral wound closure after removal of impacted mandibular third molar tooth.
- Trial name
- NCT04898816
- Testing
- closure of wound using n- butyl 2-octyl cyanoacrylate tissue adhesive, closure of wound using braided silk suture
- Where
- Malaysia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Healthy Volunteers
To Assess Safety, Tolerability and Pharmacokinetics of BI 730357 in Healthy Male Volunteers
The primary objective of the Single Rising Dose (SRD) part (trial part 1) is to investigate the safety and tolerability of BI 730357 in healthy subjects following oral administration of single rising doses after fasting and/or…
- Trial name
- NCT03004404
- Testing
- BI 730357
- Where
- Germany
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Mental Disorder, Smoking Cessation
Effectiveness of a Smoking Cessation Quit Line for Mental Health Patients
Pragmatic randomized clinical trial, single-blind, with allocation 2:1 [Intervention Group (IG) and control group (CG)] in 5 acute hospitals.
- Conditions
- Mental Disorder, Smoking Cessation, Motivation
- Trial name
- QUITMENTAL (NCT03230955)
- Testing
- Psychological and psycho-educational support by phone, Brief counselling session
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Institut Català d'Oncologia
Soft Tissues According to the Abutment Torque, Microleakage Accordint to the Abutment Torque
Impact of Abutment Screw Torque on Marginal Bone Loss
The objective of this clinical trial is to evaluate the impact of different torque values applied during transmucosal abutment placement in dental implants on marginal bone loss and peri-implant parameters, including the…
- Conditions
- Soft Tissues According to the Abutment Torque, Microleakage Accordint to the Abutment Torque, PROMS According to the Abutment Torque, Marginal Bone Loss According to the Abutment Torque
- Trial name
- NCT07234552
- Testing
- Abutment torqued to 15 Ncm, Pilar torqued to 30 Ncm, 2 mm healing cap
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Liposomal Bupivacaine
Exparel Versus Bupivacaine in Post-operative Pain Control
This is a prospective, randomized study to evaluate anaesthetic parameters, postoperative analgesia and oral analgesic consumption comparing exparel (liposomal bupivacaine) vs. standard bupivacaine
- Trial name
- NCT06547255
- Testing
- Bupivacaine liposome injectable suspension
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Endotracheal Intubation in Bed up Head Elevation Position in Rapid Sequence Induction
Comparison of Bed up Head Elevated Position With Sniffing Position in Rapid Sequence Induction.
This study is aimed to conduct a randomised controlled trial comparing endotracheal intubation (ETI) in bed up head elevation BUHE position versus sniffing position in simulated rapid sequence induction (RSI).
- Trial name
- NCT03912935
- Testing
- comparison between two different intubating position
- Where
- Malaysia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Cardiovascular Disease Risk Reduction
Flavonoids, Blood Pressure and Blood Vessel Function
The primary aim of this placebo-controlled study is to determine whether flavonoids beneficially affect markers of cardiovascular disease risk in healthy subjects at elevated cardiovascular risk.
- Trial name
- FASTCHECK (NCT01530893)
- Testing
- Flavanone - supplement, Flavanone - food, Isoflavone - supplement
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Orthodontic Appliance
Speed of Premolar Extraction Space Closure: Every Visit Replacement of Working Archwire
The aims of this trial were to assess the effect of changing 0.019X0.025-inch SS working archwire monthly on the rate of space closure, to compare the frictional resistance of unchanged and new working archwires in-vitro, and to…
- Trial name
- NCT04549987
- Testing
- Space closure without changing working archwire monthly, Space closure withchanging working archwire monthly
- Where
- Jordan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Wound Complication
Cesarean Skin Incision Trial
The purpose of this study is to determine if there is a difference between Pfannenstiel and midline vertical skin incision at time of cesarean section in preventing wound complications in the morbidly obese patient.
- Trial name
- C-SIT (NCT01897376)
- Testing
- Pfannenstiel incision, vertical skin incision
- Where
- 2 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pain
Comparative Evaluation of Post-endodontic Pain Using Two Rotary Instrumentation Systems
In this study the investigators aim to compare the post-operative pain using two single-file endodontic rotary systems : Reciproc and One shape.
- Trial name
- NCT02621034
- Testing
- Control, Reciproc, One shape
- Where
- Iran
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Zahedan University of Medical Sciences
Dry Eye Syndromes
Effect of Nursing Care on Prevention of Dry Eye
Clinical trial for prevention, randomized controlled, parallel, double-blind, with three arms, which purpose is verify the nursing interventions (artificial tear gel and liquid artificial tears)effects to prevent dry eye in adult…
- Trial name
- NCT02767258
- Testing
- LACRIBELL®, VIDISIC® GEL
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Diego Dias de Araújo
Child Obesity
Efficacy of Nuts in Obese Children.
Obesity is a problem of ever-growing importance, especially in industrialized countries, both in adults and in the pediatric population.
- Trial name
- NCT03870984
- Testing
- wNUTS, low-caloric diet plus nuts, w/oNUTS, low-caloric diet without nuts
- Where
- Italy
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Posterior Maxilla Edentulous Patients With Insufficient Alveolar Bone Height
Sinus Floor Elevation Using Separately Two Different Xenografts - A Prospective Randomized Clinical Trial
The purpose of this study is to compare the regenerative results of using separately two different xenografts after two-step sinus floor elevation.
- Trial name
- NCT01781221
- Testing
- Alpha-Bio's GRAFT Natural Bovine Bone, Bio-Oss xenograft
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital of Cologne
Alveolar Bone Loss
Pontic Site Development Using Soft Tissue Augmentation
in patients with vertical or horizontal defective of there ridge it is difficult to have prosthetic restoration with natural appearance emetating and simulating the adjacent abutment emergence profile so this study aims to…
- Trial name
- NCT03834649
- Testing
- partially de-epithelized connective tissue graft, Mucograft
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nouran Abdulla Mater,MD
Renal Insufficiency
A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Kidney Problems
This study is open to people with and without kidney problems. People can join the study if they are 18 years or older and have a body mass index (BMI) between 18.5 and 35 kg/m2.
- Trial name
- NCT05718843
- Testing
- BI 425809
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Depression, Anxiety
Mediterranean-style Dietary Pattern (MDP), Mood and Anxiety
Observational studies and a limited numbers of RCTs have observed that habitual Mediterranean-style dietary pattern (MDP) consumption is associated with improved mental health and cognition.
- Trial name
- MediMood (NCT05927376)
- Testing
- Mediterranean diet, Western diet
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Healthy
Safety, Tolerability and Pharmacokinetics of BI 1026706 in Healthy Chinese and Japanese Male Volunteers
Safety and tolerability of BI 1026706 in healthy Chinese and Japanese male subjects following oral administration of single rising doses (SRD) followed by multiple rising doses (MRD)
- Trial name
- NCT02652416
- Testing
- BI 1026706
- Where
- Japan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
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