Clinical trials: Randomised Clinical Trial
Sleep, Gerontology
Nurse-Led Elderly Sleep Intervention
The present clinical trial aims to test whether a dual program of physical activity and cognitive training improves sleep and quality of life in people over 65 years of age.
- Conditions
- Sleep, Gerontology, Physical Therapy, Cognitive
- Trial name
- NCT07251452
- Testing
- Otago programme, Otago programme + Cognifit, Control
- Where
- Spain
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Pityriasis Versicolor
Mycological Efficacy and Safety of Ketoconazole 2% Shampoo With a Seven-Day Versus Three-Day Treatment Duration in Pityriasis Versicolor
The goal of this clinical study is to find out whether using ketoconazole 2% shampoo for seven days works better than using it for three days in treating pityriasis versicolor.
- Trial name
- NCT07471178
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
HIV Infections
HIV Prevention Counseling for Men Who Have Sex With Men
The purpose of this study is to see if a behavioral intervention, a special kind of counseling, can reduce the risk of HIV infection in men who have sex with men.
- Trial name
- NCT00000931
- Testing
- Behavioral intervention, Risk-reduction counseling
- Where
- 6 sites in United States
- Volunteers
- 4,350 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Osteoarthritis
Patient Controlled Epidural Analgesia Versus Local Infiltration Analgesia Following Knee Arthroplasty
The purpose of this study was to determine if the method of peri-operative analgesia used following total Knee Replacement surgery affected the progress towards rehabilitation goals and to determine whether the analgesia had any…
- Trial name
- NCT02478372
- Testing
- Patient Controlled Epidural (PCEA), Local Infiltration Analgesia (LIA)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Golden Jubilee National Hospital
Stroke, Silent Cerebral Infarction
Intervention With Cerebral Embolic Protection in TEVAR: Gaseous Protection
Vascular brain infarction (VBI) occurs in 67% of patients undergoing TEVAR. Overt stroke occurs in 13% of these patients and 88% of patients suffer from neurocognitive impairment.
- Conditions
- Stroke, Silent Cerebral Infarction, Neurocognitive Dysfunction, Vascular Brain Injury
- Trial name
- INTERCEPT:GP (NCT03886675)
- Testing
- CO2 flushing, Saline flushing
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Halitosis, Orthodontic Appliance Complication
Chios Mastic Mouthwash and Halitosis and Oral Hygiene in Orthodontic Patients
Halitosis is the third most common oral condition perceived by the patients as pathologic, after caries and periodontal diseases.
- Trial name
- NCT05647369
- Testing
- Mastic mouthwash
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Iosif Sifakakis
Periodontitis
Administration of L. Paracasei 28.4 as an Adjunct to the Treatment of Periodontitis
The aim of this study is to evaluate the effects of probiotic administration of L. paracasei 28.4 as an adjunct to the non-surgical periodontal treatment in patients with periodontitis.
- Trial name
- NCT05107622
- Testing
- FMUD+Probiotic
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Vital Pulp Therapies
Direct Pulp Capping Versus Pulpotomy for Primary Molars
Dental caries is one of the most prevalent chronic diseases worldwide. Interventions for treating deep carious lesions in teeth with no history of pain or teeth with reversible pulpitis are referred to as vital pulp therapy…
- Trial name
- MTA (NCT06973057)
- Testing
- Pulpotomy, Direct pulp capping (DPC)
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Malaria, Falciparum, Anemia
Liberia Insecticide Treated Durable Wall Linings Study: Protocol for a Cluster Randomised Trial (DL)
A cluster-randomized control trial will study the effect of insecticide-treated wall lining on malaria transmission in Bomi County, Liberia.
- Trial name
- NCT02448745
- Testing
- Insecticide treated wall lining
- Where
- Liberia
- Volunteers
- 6,317 people, healthy volunteers welcome
- Sponsor
- The Mentor Initiative
Irritant Contact Dermatitis Due to Incontinence, Diaper Rash
Comparison of Wash Wipes and Standard Care in the Prevention of Incontinence-associated Dermatitis in Elderly
Incontinence is a widespread problem in all health care setting. One of the main complications of incontinence is inflammation of the skin in the genital and anal region, also known as incontinence-associated dermatitis (IAD).
- Conditions
- Irritant Contact Dermatitis Due to Incontinence, Diaper Rash, Pressure Ulcer, Incontinence-associated Dermatitis
- Trial name
- NCT02475512
- Testing
- Wash wipes (3M), water and pH neutral soap
- Where
- 11 sites in Belgium
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- University Ghent
Immune Function
Effect of Fruit and Vegetable Consumption on Immune Function in the Elderly
The immune system undergoes a range of changes as individuals become elderly. These may manifest as an increasing susceptibility to infection or a tendency to develop autoimmune or malignant disease.
- Trial name
- ADIT (NCT00858728)
- Testing
- 5 portions, 2 portions
- Where
- United Kingdom
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Music Therapy
The Effect of Music Therapy Applied to Pregnant Women on Anxiety and Stress
Anxiety and stress increase in primiparous pregnant women and especially in the third trimester of pregnancy. This study was conducted to investigate the effect of music therapy applied to pregnant women who will give birth for…
- Trial name
- NCT05195307
- Testing
- Music Group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Overactive Bladder, Detrusor, Overactive
TPTNS: Home vs Hospital Treatment for Overactive Bladder
Comparison of home versus hospital Transcutaneous Posterior Tibial Nerve Stimulation (TPTNS). TPTNS has been shown to be an effective treatment of overactive bladder in hospital.
- Trial name
- NCT03727711
- Testing
- TPTNS
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Colorectal Cancer
Dissemination of Colorectal Cancer Screening to Primary Care Physicians
The aim is to assess the efficacy of an intervention, academic detailing, a brief, frequently repeated educational program, on increasing recommendations for colorectal cancer screening among primary care providers by comparison…
- Trial name
- NCT00441311
- Testing
- Academic Detailing
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Columbia University
Healthy
Evaluating a Digital Single-session Intervention for Adolescent Mental Health in New Zealand
Currently, one in five rangatahi (young people) in Aotearoa report difficulty accessing support for their mental health concerns.
- Trial name
- NCT06896071
- Testing
- Project SOLVE, Project Success
- Where
- New Zealand
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Waikato
Root Canal Treatment, Postoperative Pain
Different Kinematics Within a Single-File System and Postoperative Pain
The goal of this clinical trial is to evaluating the influence of single file rotary system for root canal instrumentation using different kinematics on postoperative pain, the primary purpose: measuring post-operative pain by…
- Conditions
- Root Canal Treatment, Postoperative Pain, Apical Periodontitis
- Trial name
- NCT07699432
- Testing
- Twisted Adaptive motion (TFA), canal pro jeni, forward reciprocation
- Where
- Jordan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Impacted Mandibular Third Molar Extraction
Piezo-surgery Technique and Intramuscular Dexamethasone Injection to Reduce Postoperative Pain After Impacted Mandibular Third Molar Surgery
The purpose of my study is to test the effect of using piezosurgery and dexamethasone injection in the surgical extraction of impacted mandibular third molars, on Postoperative Pain.
- Trial name
- NCT04889781
- Testing
- Dexamethasone injection, Piezosurgery, Conventional Rotatory instruments
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Military Healthcare - Oral and Maxillofacial Surgery Department
Mpox (Monkeypox), Vaccination
Phase 3 Infant Safety & Immunogenicity Trial of MVA-BN® in DRC
This Phase 3 double-blinded, randomized study aims to evaluate the safety and immunogenicity of the two-dose MVA-BN mpox vaccine regimen, administered subcutaneously, in infants and children aged 4 to 24 months in the Democratic…
- Conditions
- Mpox (Monkeypox), Vaccination, Immunogenicity, Safety
- Trial name
- PregInPoxVac (NCT06844487)
- Testing
- MVA-BN standard regimen, MVA-BN half-dose regimen
- Where
- Democratic Republic of the Congo
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Jean-Pierre Van geertruyden
Dry Socket, Postoperative Infections
The Effect of Chlorhexidine + Hyaluronic Acid on Postoperative Wound Healing After Lower Third Molar Removal
Our aim is to evaluate chlorhexidine-hyaluronic acid containing gel on postoperative wound healing regarding impacted lower third molar surgery.
- Trial name
- NCT07044219
- Testing
- Third molar surgery
- Where
- Hungary
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Perimenopausal Women
Health Education in Perimenopausal Women to Promote Self-care and Quality of Life
Objective: To evaluate the efficiency of a group intervention opposite to the usual care to improve the quality of life, measured with the SF-12 questionnaire, in women between 45-55 years to the primary health care centres.
- Trial name
- NCT02403336
- Testing
- Training health professionals, Behavioral group intervention, Usual clinical practice
- Where
- Spain
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- Gerencia de Atención Primaria, Madrid
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