Clinical trials: Randomised Clinical Trial
Clinical Performance
Evaluation of Cervical Restorations Performance Using Modified Universal Adhesive
Class V restorations are evaluated to reveal whether the use of modified universal adhesive will have a similar performance compared to conventional universal adhesive or not.
- Trial name
- NCT05509127
- Testing
- Modified universal adhesive, Conventional universal adhesive
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Horizontal Alveolar Ridge Deficiency
Autobone and Bioactive Glass With Ridge Splitting
Objective: To compare the use of autogenous bone graft versus autogenous bone graft mixed with bioactive glass bone graft in the treatment of maxillary anterior horizontal bone defects by ridge splitting technique combined with…
- Trial name
- NCT04814160
- Testing
- mixture of bioactive glass and autogenous bone graft, autogenous bone graft
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Bone Resorption
Alveolar Ridge Preservation With Different Grafting Strategies
The aim of the present study was to compare the half-packed grafts that are covered with either a collagen or a nonresorbable membrane to the conventional alveolar ridge preservation procedures involving full-packed grafts and…
- Trial name
- NCT06049823
- Testing
- Alveolar ridge preservation
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Mandibular Body Fracture
3D Titanium Plates for Mandibular Body Fracture Fixation
Mandibular body fracture pose significant challenges in maxillofacial surgery due to their frequency, potential for functional impairment, and aesthetic concerns.
- Trial name
- NCT07651059
- Testing
- 3D Titanium Plates
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sprains and Strains
Kinesio Tape Effects on Ankle Proprioception
The aim of the present study was to establish whether Kinesio Tape (KT) on the ankle (Kase protocol for the lateral ankle ligament) improves Joint Position Sense (JPS) in healthy volunteers immediately after its application and…
- Trial name
- NCT01792908
- Testing
- Kinesio tape
- Where
- Spain
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Osteoarthritis of the Knee
Genicular Radiofrequency Ablation for Unilateral Knee Arthroplasty Pain Management
Three primary reasons prolong hospital stays following unilateral knee arthroplasty. Pain is the primary reason followed by opioid drowsiness and nausea/vomiting side effects.
- Trial name
- RFA (NCT02925442)
- Testing
- t-RFA, C-RFA, Control
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Lyman Medical Research Foundation, Inc.
HIV
A Trial In Healthy HIV-Negative Women To Assess The Effect Of Menses And Tampon Use On The Pharmacokinetics Of Dapivirine, Delivered By Dapivirine Vaginal Ring-004, Containing 25 Mg Of Dapivirine
A Two-Cohort, Open-Label, Randomised, Three-Period Crossover Trial In Healthy HIV-Negative Women To Assess The Effect Of Menses And Tampon Use On The Pharmacokinetics Of Dapivirine, Delivered By Dapivirine Vaginal Ring-004…
- Trial name
- NCT02858024
- Testing
- Dapivirine Vaginal Ring-004 and no tampons, Dapivirine Vaginal Ring-004 with tampons, Dapivirine Vaginal Ring-004 with no menses
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Overweight, Obesity
Evaluation of a Family Intervention Program for the Management of Overweight or Obese Children
Objectives: To evaluate the effectiveness of the Nereu program compared to standard care (advice on increased physical activity and nutrition) such as a health intervention tool for the childhood obesity management…
- Conditions
- Overweight, Obesity, Children
- Trial name
- NEREU (NCT01878994)
- Testing
- Counselling group, Nereu group
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Photobiomodulation Therapy
Reversal of Anaesthesia with Diode Laser
Background: After local anesthesia, which is frequently used in pediatric dentistry, long-term soft tissue numbness can cause various problems.
- Trial name
- NCT06841120
- Testing
- Actual laser application
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
HIV/AIDS
A Cluster Randomised Trial of Community-led Distribution of HIV Self-tests in Rural Malawi (HIV Self-Testing Africa [STAR])
The aim of this study is to determine the benefits, costs and safety of community-led delivery of HIV self-testing (HIVST) kits in rural Malawi, with a focus on testing and linkage to care and prevention services among defined…
- Trial name
- NCT03541382
- Testing
- OraQuick® HIV Self-Test
- Where
- Malawi
- Volunteers
- 7,880 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Osteoarthritis of the Knee
Effects of Aquamin F on NSAID Dose Reduction in Osteoarthritis of the Knee
The objective of this trial is to evaluate the effect of Aquamin F versus placebo on NSAID (non-steroidal anti-inflammatory drug) dose reduction in subjects with osteoarthritis of the knee.
- Trial name
- NCT00755482
- Testing
- Aquamin F
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Marigot Ltd.
Maxillary Transverse Deficiency
MARPE Effect With/Without MOP in Non-growing Patients
This study compares the effect of MARPE (mini-implant assisted rapid palatal expansion) versus MARPE+ MOP (Micro-osteo-perforation) on nasal airway and maxillary transverse deficiency in non-growing patients.
- Trial name
- NCT06502041
- Testing
- MARPE with MOP, MARPE without MOP
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Anaesthesia, Airway Management
Randomised Controlled Trial of Intubation, Comparing Pentax AWS Against Macintosh Laryngoscope.
A randomised controlled trial of intubation by inexperienced anaesthetists, comparing the The Pentax Airway Scope AWS-S100 Rigid Video Laryngoscope(Pentax AWS) and the Macintosh Laryngoscope.
- Conditions
- Anaesthesia, Airway Management, Videolaryngoscopy
- Trial name
- PAWS (NCT01029756)
- Testing
- Macintosh Laryngoscope, Pentax AWS Videolaryngoscope
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- NHS Grampian
Gingival Recession
A Novel Vertical Y-shaped Tunnel Approach Versus Modified Coronally Advanced Tunnel Technique, for The Treatment of Miller Class I Gingival Recession
Recent plastic procedures have provided satisfactory results in the treatment of gingival recession but there is, presently, a greater need for procedure that cause less surgical morbidity as also provide improved results.
- Trial name
- NCT06453369
- Testing
- Y shaped Tunnel with Connective tissue graft
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- October 6 University
Dentinal Hypersensitivity
Efficacy of Sensi-IP Toothpaste in the Treatment of Dentinal Hypersensitivity Compared to a Sodium Fluoride Toothpaste
The study is designed as a prospective, randomized, parallel arm, double blinded, pilot clinical trial.The primary objective is to evaluate the efficacy of Sensi-IP +NaF as compared to a NaF toothpaste in the reduction of dentin…
- Trial name
- NCT06166745
- Testing
- Sensi-IP toothpaste, Sodium Fluoride Toothpaste
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- IR Scientific Inc.
Healthy
A Study to Test How Well Healthy Men Tolerate Different Doses of BI 1356225
The main objectives of the SRD part of this trial are to investigate safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of BI 1356225 in healthy male subjects following oral administration of single rising…
- Trial name
- NCT04065295
- Testing
- BI 1356225
- Where
- Germany
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Burn Out
Effect of Physician Peer Coaching on Burnout in Hospital-Based Physicians: A Pilot Randomized Clinical Trial
The prevalence of burnout symptoms among physicians is high, especially for acute care physicians. Physician burn out is a long-term stress reaction marked by emotional exhaustion, depersonalization, and a lack of sense of…
- Trial name
- NCT05251675
- Testing
- Physician Led Professional Coaching, Delayed Physician Led Professional Coaching
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Complete Edentulism
Patient Satisfaction and Crestal Bone Changes Around One-piece Zirconia(Zr) and Titanium(Ti) in Implant-Retained Mandibular Overdenture
This interventional randomized clinical trial study is conducted to assess patient satisfaction and crestal bone changes around one-piece Zr and Ti Implants in mandibular implant-retained overdenture in completely edentulous male…
- Trial name
- (Zr) - (Ti) (NCT06643975)
- Testing
- One-piece zirconia dental implants, One-piece titanium dental implants
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Peri-Implant Mucositis, Peri-implantitis
Impact of an AI-Based Chatbot on Implant Patient Management: RCT
Background: Dental implant therapy is a well-established and predictable procedure for replacing missing teeth, with high long-term survival rates.
- Conditions
- Peri-Implant Mucositis, Peri-implantitis, Peri-Implant Health, Peri-implant Inflammation
- Trial name
- NCT07300657
- Testing
- AI Chatbot, Standard Oral Hygiene Education
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Catania
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
high-quality evidence is needed to add to current knowledge and also assess the long-term outcomes for full/complete pulpotomy after carious pulpal exposure in patients with signs and symptoms indicative of irreversible pulpitis
- Trial name
- NCT05726357
- Testing
- vital pulp therapy
- Where
- Egypt
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
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