Clinical trials: Randomised Clinical Trial
Self-Criticism
Understanding and Intervening With State Shame and Self-criticism
The goal of this clinical trial is to compare the momentary effects of a one-session intervention (compassion-based, logic-based, or placebo control) on individuals with high or low trait self-criticism.
- Trial name
- NCT06200675
- Testing
- Compassion-based intervention, Logic-based intervention
- Where
- Canada
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Cancer of the Cervix, Cervical Intraepithelial Neoplasia
Compass - Randomised Controlled Trial of Primary HPV Testing for Cervical Screening in Australia
Compass is a randomised controlled trial of primary HPV testing for cervical cancer screening in Australia. A pilot study involving 5,000 women was carried out in 2013-2014.
- Trial name
- Compass (NCT02328872)
- Testing
- Molecular testing for HPV, Liquid Based Cytology
- Where
- Australia
- Volunteers
- 76,181 people, healthy volunteers welcome
- Sponsor
- VCS Foundation
Mobility Limitation
Walking Aid and Locomotion Knowledge in Emergency Rooms (WALKER 1) for Elderly People
Older adults have higher rates of emergency department admissions when compared to their younger counterparts. Mobility is the ability to move around but also encompasses the environment and the ability to adapt to it.
- Trial name
- WALKER 1 (NCT05950269)
- Testing
- Walking aid, Telemonitoring, Guidance on safe walking and risk of falling
- Where
- Brazil
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Hospital Sirio-Libanes
Ketogenic Dieting, Weight Loss
Weight Loss for a Healthier You Programme
In view of the research gap in the safety of traditional ketogenic diet, there is a need for a healthy alternative to the ketogenic diet that reduces the individual's propensity to adverse diet choices.
- Conditions
- Ketogenic Dieting, Weight Loss, Obesity, Metabolic Syndrome
- Trial name
- NCT05049954
- Testing
- Calorie-Restricted Healthy Ketogenic Diet, Calorie-Restricted Low Fat Diet
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Exercise
A Multi-component Physical Activity Intervention for Adolescent Girls
A four-arm randomised pilot trial involving: 1. Physical activity programme only - live exercise sessions, social support, standardised text messages 2.
- Trial name
- NCT04766372
- Testing
- Behaviour change
- Where
- 3 sites in Ireland, United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Arthrocentesis
Injection of Tenoxicam Versus Arthrocentesis Alone in the Treatment of Temporomandibular Joint Osteoarthritis
The aim of the study is to examine the effectiveness of arthrocentesis plus tenoxicam injection and to compare it with arthrocentesis alone in patients with TMJ-OA.
- Trial name
- NCT05497570
- Testing
- Tenoxicam Injectable Product
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Vagina; Anomaly, Puerperium; Disease
HYDEAL-D® Application for Promoting the Restoration of Sexual Function in the Postpartum Period
During postpartum and lactation, vaginal epithelium tends to have an impaired degree of hydration and lubrication. This may lead to vaginal dryness, burning sensation dyspareunia or itching, which negatively affect the sexual…
- Conditions
- Vagina; Anomaly, Puerperium; Disease, Sexual Dysfunction
- Trial name
- HYDEAL-D (NCT04560283)
- Testing
- Vaginal gel HYALOGYN®, Expectant management
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ospedale Policlinico San Martino
Post-traumatic Stress Disorder, Depression
Randomized Control Trial of Group Intervention With Former War-affected Boys in the Democratic Republic of Congo
The purpose of this study is to evaluate, in a randomised control trial (RCT), the effectiveness of group-based, trauma-focused Cognitive Behaviour Therapy (TF-CBT) in reducing psychological distress in former child soldiers and…
- Conditions
- Post-traumatic Stress Disorder, Depression, Conduct Disorder
- Trial name
- NCT01494831
- Testing
- TF-CBT
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Healthy
Relative Oral Bioavailability of BI 44847 as Suspension Compared to Tablet and the Influence of Food Anf of BI 44847 as Solution Compared to Tablet in Healthy Male Volunteers
Study to investigate the relative oral bioavailability of 400 mg BI 44847 as suspension vs. 400 mg BI 44847 as tablet, to investigate a food effect on the 400 mg tablet pharmacokinetic (PK) and to investigate relative oral…
- Trial name
- NCT02211937
- Testing
- BI 44847 solution, low dose, BI 44847 suspension, high dose, BI 44847 tablet, low dose
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Resilience, Anxiety
Music Breathing in Enhancing Resilience Among Elders at Risk of Mental Health Problems
The goal of this pilot randomised controlled trial is to examine the effects of a mindfulness-based music breathing intervention in enhancing resilience (primary outcome), and in reducing anxiety, depressive symptoms, loneliness…
- Conditions
- Resilience, Anxiety, Depressive Symptom, Loneliness
- Trial name
- NCT07631845
- Testing
- Mindfulness-based music breathing intervention, control group
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Cleft Lip and Palate
Effectiveness of a Customized 3D Printed Nostril Retainer Combined With Taping Vs.Taping Only on Enhancing the Nasolabial Esthetics and Maxillary Arch Dimensions in Infants With Unilateral Complete Cleft Lip and Palate.
Lip taping was proven as simple, handy technique of PSIO for alveolar molding yielding enhanced maxillary arch dimensions in UCCLP infants.
- Trial name
- NCT06211205
- Testing
- Customized 3D printed nostril retainer combined with lip taping, Lip taping
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy
Toddler Milk Intervention Trial
To assess growth of children (enrolled between 11.5 and 13.5 months) fed with two iso-energetic, young-child formulas with different protein content during the second year of life
- Trial name
- NCT02907502
- Testing
- Young-child formula with low protein content, Young-child formula with protein content similar to that of cow's milk
- Where
- 2 sites in Germany, Spain
- Volunteers
- 1,618 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Obesity
A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver
This study is open to adults with obesity. People with a body mass index (BMI) in the range from 30 to 40 kg/m2 and a body weight of 70 to 150 kg can participate in the study.
- Trial name
- NCT05202353
- Testing
- BI 456906, Semaglutide
- Where
- Netherlands
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy People to Test Whether BI 730357 Affects How 4 Other Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Taken up in the Body
The main objective of this trial is to investigate the effect of BI 730357 under steady state conditions on the pharmacokinetics of digoxin, furosemide, metformin and rosuvastatin given as a cocktail (Reference, R: cocktail…
- Trial name
- NCT04590937
- Testing
- BI 730357, CRESTOR®, Lenoxin®
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Influenza Virus Infection
Direct and Indirect Benefits of Influenza Vaccine Versus Placebo in Healthy Children
While immunisation of school-age children against influenza is not recommended in Hong Kong, past experience in Japan and elsewhere suggests that immunisation of children may protect the wider community through its indirect…
- Trial name
- NCT00792051
- Testing
- Inactivated influenza vaccine, Saline
- Where
- China
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Orthodontic Appliance Complication
The Effects of Different Storage Conditions on Removable Retainers
Orthodontic removable retainers are appliances that hold the position of the upper and lower teeth after fixed braces treatment and they can be removed from a patient's mouth.
- Trial name
- NCT05854953
- Testing
- Hawley retainers in dry storage condition, Hawley retainers in wet storage condition, VFRs in dry storage condition
- Where
- Malaysia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Hypertension
Trial of a Nurse Led Hypertension Clinic in Inner City General Practices
The investigators will do a trial in two general practices to see if the introduction of a blood pressure clinic staffed by a specialist nurse supported by visiting consultant improves blood pressure control compared to usual…
- Trial name
- NCT01101737
- Testing
- Nurse-led blood pressure clinic
- Where
- United Kingdom
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Medication Safety, Patient Safety
Co-Development and Evaluation of a Complex Intervention to Increase Medication Safety in Nursing Homes
The study aims to develop and evaluate a new, multifaceted (complex) intervention in a mixed methods study-design to increase medication safety in nursing homes.
- Trial name
- SAME (NCT04990986)
- Testing
- Complex intervention
- Where
- Denmark
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- Anne Estrup Olesen
Pain, Postoperative, Endodontically Treated Teeth
Postoperative Pain Intensity Associated With the Use of Different Nickel Titanium Instrumentation Systems
In this study the effect of different engine-driven nickel titanium (Ni-Ti) instrumentation systems (OneShape, Revo S and WaveOne) on postoperative dental pain in patients with asymptomatic teeth after a single-appointment root…
- Trial name
- NCT03478241
- Testing
- Group 1: single file rotary motion, Group 2: multiple file rotary motion, Group 3: single file reciprocal motion
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Obesity, Lung Functions
The Effect of CLA on Obesity, Lung Functions, Lipid Profile and Inflammation in Women With BMI≥25
Conjugated linoleic acid or CLA, is one of the food supplements that could be found in meat, fats, and dairy products of ruminants which has been fed grass not on grains.
- Conditions
- Obesity, Lung Functions, Inflammation, Lipid Disorder
- Trial name
- NCT04641494
- Testing
- Conjugated linoleic acid, High oleic acid safflower oil capsules
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Chester
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.