Clinical trials: Randomised Clinical Trial
Adiposity
Ectopic Adipose Tissue, Exercise Training and IL-6
Aim: Exercise training improves the risk of cardiometabolic diseases; yet the underlying mechanisms are unclear. Exercise induces release of IL-6 from skeletal muscle.
- Trial name
- NCT02901496
- Testing
- Endurance Exercise Training, Resistance Exercise Training, No Exercise
- Where
- Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Respiratory Syncytial Virus Infections
A Study to Learn About the Drug-drug Interactions of Sisunatovir in Healthy Adult Participants
The purpose of this clinical trial is to learn about the interaction of sisunatovir with four medications (midazolam, itraconazole, rifampicin, and verapamil).
- Trial name
- NCT03782662
- Testing
- Itraconazole, Verapamil, Rifampicin
- Where
- United Kingdom
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Pfizer
Stress, Anxiety
Effects of High Ventilation Breathwork With Retention (HVBR) on Health
The investigators are conducting a randomised-controlled trial comparing high ventilation breathwork with retention (HVBR) to a breathwork placebo (paced breathing at 15breaths/min with brief retentions).
- Conditions
- Stress, Anxiety, Depressive Symptoms, Mental Wellbeing
- Trial name
- NCT06064474
- Testing
- High ventilation breathwork with retention (HVBR)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sussex
Telemedicine
Smartphone Applications to Improve Lifestyles in Olders Over 65 Years
This is a randomized controlled clinical trial performed in urban primary care centers in Salamanca (Spain). Its objective is to evaluate the effect of an intervention based on the use of new information and communication…
- Trial name
- EVIDENT-Age (NCT03574480)
- Testing
- Intervention (training in use of a Smartphone application), Control (Advice on healthy diet and physical activity recommendations)
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
HIV Infections
Safety and Pharmacokinetic Trial in Healthy HIV-Negative Women to Assess the Delivery of Dapivirine From a Vaginal Ring
The proposed study is a single center, double-blind placebo-controlled trial to assess the safety and tolerability of the dapivirine ring as compared to a placebo ring when inserted for 28 days in 16 healthy, HIV-negative women.
- Trial name
- NCT02920827
- Testing
- Dapivirine Vaginal Ring
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Blood Pressure, Hemodynamic Response
Ischemic Preconditioning in Resistance Exercise in Older Women
This study investigates whether ischemic preconditioning (IPC) can reduce cardiac demand after resistance exercise in older women.
- Conditions
- Blood Pressure, Hemodynamic Response, Rating of Perceived Exertion, Heart Rate
- Trial name
- NCT07497659
- Testing
- Ischemic Preconditioning
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Triangulo Mineiro
Chronic Kidney Diseases, Metabolic Syndrome
Theory-based Health Behaviour Change Intervention in Patients of Metabolic Syndrome With Chronic Kidney Disease
The pilot study will adopt a 2-arm, pretest-posttest, and assessor-blind randomized controlled trial design to examine the feasibility and acceptability of a theory-based health behaviour change intervention and examine its…
- Trial name
- NCT06527768
- Testing
- Theory-based health behaviour change interventio
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Postoperative Pain, Edema
Bromelain and Escin in the Reduction of Postoperative Sequelae in Periodontal and Implant Surgery
A randomized clinical trial will be performed in parallel, placebo controlled, triple-blind to evaluate the effectiveness of the association Bromelina and Horse-chestnut (titrated in escin) (Noflogo®, Mavenpharma s.r.l., Rome…
- Conditions
- Postoperative Pain, Edema, Swelling Lips & Face
- Trial name
- NCT04657874
- Testing
- Bromelains and Escin Oral Tablet
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD)
LETHE-AT: a Personalized Multidomain Lifestyle Intervention for Individuals at Increased Risk of Memory Impairment.
The goal of this clinical trial is to learn whether a hybrid multidomain lifestyle program can prevent cognitive decline and reduce dementia risk in community-dwelling adults in mid- to late life who are at increased risk of…
- Trial name
- LETHE-AT (NCT07376135)
- Testing
- A tailored hybrid multidomain lifestyle intervention group, Self-guided multimodal lifestyle advice group
- Where
- 3 sites in Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
The Methodology Assessment of Glucose Dependent Insulin Secretion
A Study to Compare Methodologies for Assessing Glucose-Dependent Insulin Secretion (0000-104)(COMPLETED)
This study will compare graded glucose infusion (GGI) to the hyperglycemic clamp (HGC) for assessment of glucose-dependent insulin secretion (GDIS) using exenatide as a probe.
- Trial name
- NCT00782418
- Testing
- Comparator: exenatide
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Intrabony Periodontal Defects
Minimally Invasive Non Surgical Treatment Using Injectable Platelet Concentrate in Treatment of Deep Pockets.
The purpose of this study is to evaluate change in pocket depth following using minimally invasive non surgical combined with injectable platelet concentrate .
- Trial name
- NCT07722390
- Testing
- Injectable PRF, MINST
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy Mothers, Healthy Infants
Maternal High Fibre Fermented Diet Effect on Breastfed Infant Gut Microbiome
Breastfeeding is recommended for babies from birth to six months old because breast milk provides all the nutrients babies need for growth and development.
- Trial name
- MumBabyGut (NCT06977113)
- Testing
- High Fibre Fermented Food Diet, Control Habitual Diet
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Plaque Accumulation, Gingival Inflammation
Triphila Mouthwash Effect as Anti-plaque and Anti-gingivitis in Children
The study aim to to assess the antiplaque and antigingivitis efficacy of Triphala mouthwash versus chlorhexidine mouthwash among children.
- Trial name
- NCT07016659
- Testing
- 0.12% Chlorhexidine Mouthwash ( Hexitol ), Triphila mouthwash
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Individuals at Risk of Developing Diabetes
Daily vs Intermittent Restriction of Energy: Controlled Trial to Reduce Diabetes Risk (DIRECT)
In this randomized controlled trial, the investigators will compare the long term effectiveness of intermittent fasting (IF) versus an energy matched moderate calorie restriction (CR) over 18 months, and relative to a non-active…
- Trial name
- NCT03689608
- Testing
- Intermittent Fasting (IF), Daily Restriction (DR), standard care (SC)
- Where
- Australia
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Burn Scar
Fat Grafting in Skin-grafted Deep Burn Scars
fat grafting in human skin-grafted immature burn scars histological, clinical and photographic follow-up
- Trial name
- NCT03627650
- Testing
- lipofilling/ fat grafting
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Cholesterol Level, High
Effects of a Single Dose of Brazil Nuts on Blood Lipids
Several studies have shown that regular intake of nuts may improve blood lipids. However, few studies have investigated the effects on blood lipids after a single intake of nuts.
- Trial name
- NCT05537324
- Testing
- Brazil nut, Coconut
- Where
- Norway
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Skogli Health and Rehabilitation Center
Healthy Subjects
Clinical Trial to Investigate the Safety, Tolerability and Pharmacokinetics of BV100 in Male Subjects
This is a Phase 1, single-centre, double-blind, randomised, placebo-controlled study to evaluate the safety, tolerability, and pharmacokinetics of single intravenous ascending doses of BV100 to healthy male subjects.
- Trial name
- NCT04636983
- Testing
- BV100
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- BioVersys SAS
PME, Food Choice
Nutri-score Labelling in a UK Restaurant Setting: a Randomised Control Trial
An experiment exploring the perceived effectiveness of Nutri-score food labels with calorie labelling compared to calorie labelling only on food choice and consumption in a real-world setting
- Conditions
- PME, Food Choice, Food Labelling
- Trial name
- NCT06923241
- Testing
- menu labelling type
- Where
- United Kingdom
- Volunteers
- 672 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Athletic Injuries/Prevention and Control
Core Stability Training Combined With Plyometric Exercises on Vertical Jump Performance:
This study protocol investigates whether adding core stability training to a plyometric training program enhances vertical jump performance in elite high jump athletes over a six-week period.
- Trial name
- NCT07573605
- Testing
- Core stability exercises with plyometric training, Plyometric exercise alone
- Where
- United Arab Emirates
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Necrotic Primary Teeth
Evaluation of Antimicrobial Potency of Garlic Lemon Extract Irrigant Versus Physiological Saline Irrigant
To evaluate the antimicrobial potency of Garlic Lemon extract irrigant versus physiological saline irrigant following partial pulpectomy in primary molars.
- Trial name
- NCT06759766
- Testing
- Garlic-Lemon Extract irrigant, physiological saline
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.