Clinical trials: Randomised Clinical Trial
Depressive Symptoms, Hypomania Nos Single Episode or Unspecified
A Study of Aerobic Exercise for Adolescents With Subthreshold Mood Syndromes
This study will investigate the effects of aerobic exercise on mental states, cognition, and long-term outcomes in adolescents with subthreshold depressive and/or hypomanic syndromes and in non-clinical school children
- Trial name
- NCT03300778
- Testing
- aerobic exercise
- Where
- China
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Guangzhou Psychiatric Hospital
Healthy
A Two-Week Study of an Anticavity Low pH Mouthwash
The purpose of this clinical trial is to evaluate the oral tolerance of a new, experimental mouthwash compared to two mouth rinse formulations, which are already marketed, as well as compared to a tooth brushing only control…
- Trial name
- NCT06010758
- Testing
- Listerine Experimental Mouthwash, Colgate Cavity Protection Toothpaste, Listerine Total Care Zero
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Gingival Recession
Root Biomodification With Citric Acid and Tetracycline Improves the Outcomes of Root Coverage
The aim of this study is to investigate the effects of the application of a citric acid + tetracycline gel solution during 90 or 180 seconds compared to no conditioning in the outcomes of treatment of Miller's class I or II…
- Trial name
- NCT02259543
- Testing
- Root conditioning with citric acid+tetracycline solution
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Asymptomatic Necrotic Teeth
Effect of Triple Antibiotic Paste as an Intracanal Medication With an Anti-Inflammatory Drug on Post-operative Pain.
The purpose of this study is to determine whether the use of triple antibiotic paste as intracanal medication with an anti-inflammatory drug, compared to a calcium hydroxide will reduce postoperative pain and intracanal bacteria…
- Trial name
- NCT02907489
- Testing
- triple antibiotic paste with an anti-inflammatory drug
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Diseases
The Use of Leucocyte Platelet Rich Fibrin (L- PRF) Covered Perforated Guided Tissue Membrane for Treatment of Periodontal Intrabony Defects
This study is the first to investigate the effect of leucocyte platelet rich fibrin (L-PRF) combined with perforated membrane in order to treat infrabony defects and assess their combined effect in clinical attachment level gain…
- Trial name
- NCT04576468
- Testing
- Open flap debridement, perforated membrane, leucocyte - platelet rich fibrin
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obesity, Childhood, Cognition
NiPPeR Randomised Trial - Child Follow Up Study
There is an increasing focus on the need to optimise nutrition, lifestyle and metabolism of parents before and during pregnancy and of the infant after birth, but as yet there is limited understanding of the specific influences…
- Conditions
- Obesity, Childhood, Cognition, Neurobehavioral Manifestations, Metabolic Disturbance
- Trial name
- NiPPeR Child (NCT05934422)
- Testing
- Intervention (Study Nutritional Drink), Control (Standard Nutritional Drink)
- Where
- 3 sites in New Zealand, Singapore and 1 more
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Implant Site Reaction
Assessment of Osseointegration Properties of Nano-Hydroxy Apatite Coated Titanium Implant
the purpose of this trial is to evaluate the osseointegration properties of nano-hydroxy apatite coated titanium implants in posterior maxilla.
- Trial name
- NCT05936775
- Testing
- nano-hydroxy apatite coated titanium implants, sandblasted large acid itched coated titanium implant
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Healthy Participants
Comparative Study of Two Ultrasound-guided Percutaneous Neuromodulation Protocols on Maximal Handgrip Strength.
Purpose of the Study: This study aims to compare the effects of two different ultrasound-guided percutaneous neuromodulation (PNM) protocols targeting the median nerve on maximal handgrip strength in healthy individuals.
- Trial name
- NCT07098130
- Testing
- US-guided PNM 100 Hz, US-guided PNM 10 Hz
- Where
- Spain
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Fear of Flying
Targeting Reconsolidation to Prevent Return of Fear
The overall aim of this project is to determine if using a cue to trigger (and reactivate) the fear memory 10 minutes prior to exposure treatment sessions leads to less anxiety in patients with a fear of flying.
- Trial name
- NCT01623830
- Testing
- Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Emory University
Elderly Women
Water Exercise and Vascular Function in Elderly
Objectives: The purpose of this research was to assess modifications caused by a concurrent water exercise program on plasma nitrite (NO3), cerebral vascular resistance and cholesterol in the elderly and analyze the correlations…
- Trial name
- NCT01642654
- Testing
- Exercise, Educational lectures
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Herpes Zoster
A Study of Intradermal Administration of ZOSTAVAX™ (V211-051 AM2)
This study will compare the safety and immunogenicity of ZOSTAVAX™ (V211) administered both intradermally and subcutaneously at various doses.
- Trial name
- NCT01385566
- Testing
- ZOSTAVAX™ (Zoster Vaccine Live) Full Dose Subcutaneous, ZOSTAVAX™ (Zoster Vaccine Live) 1/3 Dose Subcutaneous, ZOSTAVAX™ (Zoster Vaccine Live) Full Dose Intradermal
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Preterm Birth, Distress Respiratory Syndrome
Adverse Neonatal Outcomes With a Shortened Clinical Regimen of Dexamethasone.
Respiratory morbidity, including respiratory distress syndrome (RDS), is a serious complication of preterm birth and the leading cause of early neonatal mortality and disability.
- Trial name
- UNODEXA (NCT06569251)
- Testing
- Dexamethasone 12 mg QD, Dexamethasone 6 mg BID
- Where
- Honduras
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ricardo A Gutierrez Ramirez, MD, MSc, FACOG
Convergence Insufficiency
Randomized Trial of Treatments for Convergence Insufficiency
The Convergence Insufficiency Treatment Trial (CITT) is a multi-center, placebo-controlled, single-masked, clinical trial designed to compare the benefits of two commonly used treatment approaches for patients with convergence…
- Trial name
- NCT00347945
- Testing
- Pencil Push-ups, Office-based Vision Therapy
- Where
- 7 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pennsylvania College of Optometry
Hypercholesterolemia
Effect of the Molecular Weight of Oat β-glucan on Its Ability to Lower Serum Cholesterol
The purposes of this study were: 1. To determine if a breakfast cereal containing 3g of high molecular weight oat beta-glucan fiber would lower low-density lipoprotein (LDL) - cholesterol (the "bad" cholesterol) compared to a…
- Trial name
- Bluebird (NCT00981981)
- Testing
- Wheat bran, 3g high MW, 4g medium MW
- Where
- 5 sites in Australia, Canada and 1 more
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Glycemic Index Laboratories, Inc
Class II Malocclusion
Effectiveness of Modified Functional Appliance With Expander
This clinical trial compares the effectiveness of a myofunctional appliance that uses a clear and modified twin block appliance with an expander made from 2mm biocompatible polyethylene terephthalate modified with Glycol…
- Trial name
- NCT06116500
- Testing
- Modified twin block appliance with expander, Conventional twin block appliance with expander
- Where
- Iraq
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Body Image
The Impact of Playing Super U on Pre-adolescents' Body Image
Body image concerns can have serious physical and psychological consequences on young people, including anxiety, depression, risk taking behaviours, eating disorders and suicidal ideation.
- Trial name
- NCT05669053
- Testing
- Super U Story intervention, Alternative Roblox game, Online word search
- Where
- United Kingdom
- Volunteers
- 2,941 people, healthy volunteers welcome
- Sponsor
- University of the West of England
Deep Caries, Dentin Caries
Clinical Investigation of Effectiveness of a Calcium Silicate Cement
The aim of this clinical study is to investigate the clinical performance of a calcium silicate used in the treatment of deep caries lesions.
- Trial name
- NCT06256601
- Testing
- Theracal (calcium silicate), Dycal (calcium hydroxide)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Androgenic Alopecia
To Investigate Efficacy of FOL-005 on Hair Growth on Scalp Skin
The trial was a multicentre, randomised, double-blind, placebo controlled phase 2 trial. 60 healthy bald male subjects diagnosed with alopecia, who are between 18 and 55 years old and provide written informed consent were…
- Trial name
- NCT03467412
- Testing
- FOL-005
- Where
- 2 sites in Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Follicum AB
Osteoarthritis
Vacuum Therapy and Stabilization Splints Efficacious for the Management of Temporo-mandibular Joint Osteoarthritis
The aim of this study was to determine and compare the clinical efficacy of VT and STT alone or in combination for the patients with temporo-mandibular joint (TMJ) osteoarthritis.
- Trial name
- NCT06228612
- Testing
- vacuum therapy, maxillary stabilization splint (MSS), vacuum therapy VT and maxillary stabilization splint (MSS)
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Aromatherapy
The Efficacy of Sweet Orange Oil Inhalation in Management of Dental Anxiety and Pain
Aim of the study To evaluate the effectiveness of sweet orange oil inhalation in reducing dental anxiety and pain in children undergoing local anaesthetic administration.
- Trial name
- NCT06063512
- Testing
- sweet orange oil inhalation
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
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