Clinical trials: Randomized Clinical Trial
Aneurysmal Subarachnoid Haemorrhage
CytoSorb SAH Trial
In aSAH high levels of IL-6 (a pro-inflammatory cytokine) in the cerebrospinal fluid, as well as systemically have been linked to the severity grade and the occurrence of vasospasm and delayed cerebral ischemia caused by…
- Trial name
- NCT05259514
- Testing
- CytoSorb
- Where
- Switzerland
- Volunteers
- 2 people
- Sponsor
- Emanuela Keller
Menopause
A Randomized-Controlled Trial to Examine the Effects of a Daily Probiotic Supplement on Common Symptoms of Menopause
Symptoms of menopause can significantly affect overall quality of life. It is hypothesized that probiotic supplements can reduce the severity of these symptoms.
- Trial name
- NCT06148714
- Testing
- Provitalize Natural Menopause Probiotic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maneuver Marketing
Depression
Accelerated Transcranial Magnetic Stimulation (aTBS) to Treat Depression
The primary aims of this study are to investigate the efficacy of L DLPFC accelerated TMS (aTMS) in patients with depression in Singapore and to assess the whether a 1-week course of treatment is as effective as a 4-week course…
- Trial name
- NCT03941106
- Testing
- Accelerated repetitive transcranial magnetic stimulation
- Where
- 2 sites in Singapore
- Volunteers
- 38 people
- Sponsor
- Institute of Mental Health, Singapore
Myopia
Dietary Supplement for Myopia Control
The purpose of this clinical trial is to investigate the changes in choroidal thickness and vasculature in myopic children following oral supplementation.
- Trial name
- NCT07406906
- Testing
- Oral dietary supplement provided in a capsule format (3 active capsules/ per day)
- Where
- Hong Kong
- Volunteers
- 156 people
- Sponsor
- The Hong Kong Polytechnic University
Temporomandibular Disorder, Temporomandibular Joint Disorders
Effect of Exercises on Convergence Insufficiency in Individuals With Temporomandibular Disorders
Temporomandibular Disorder is a disorder that involves the muscles of mastication, the temporomandibular joint (TMJ), and associated structures.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome, Convergence Insufficiency
- Trial name
- NCT05761106
- Testing
- Oculomotor Therapy, Therapy for Temporomandibular Disorder
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Nove de Julho
Endometrial Carcinoma, Recurrent Fallopian Tube Carcinoma
An Automated Personalized Physical Activity Intervention to Improve Immune Function and Clinical Outcomes in Stage II-IV Ovarian, Primary Peritoneal or Fallopian Tube Cancer and Newly Diagnosed Endometrial Cancer, Life on the Go 3 Study
This clinical trial compares the effect of an automated personalized physical activity intervention supported by wearable technology to standard of care on physical activity levels and quality of life in patients with stage II…
- Conditions
- Endometrial Carcinoma, Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Primary Peritoneal Carcinoma
- Trial name
- NCT06855706
- Testing
- Behavioral Intervention, Best Practice, Biospecimen Collection
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Roswell Park Cancer Institute
Pancreatic Cancer
Study of Ruxolitinib in Pancreatic Cancer Patients
The purpose of this study was to determine whether ruxolitinib added to capecitabine is effective in improving the overall survival of patients with metastatic pancreatic cancer.
- Trial name
- RECAP (NCT01423604)
- Testing
- Capecitabine, Ruxolitinib
- Where
- 39 sites in United States
- Volunteers
- 136 people
- Sponsor
- Incyte Corporation
Urinary Incontinence
Trial Study of the Efficacy of Intensive Preoperative Pelvic Floor Muscle Training to Decrease Post-prostatectomy Urinary Incontinence
Urinary incontinence after radical prostatectomy is a significant clinical problem despite advances in surgical techniques. In the literature, the incidence of post prostatectomy urinary incontinence varies widely from 0.5 to 87%…
- Trial name
- NCT01338584
- Testing
- Pelvic floor muscle training 3 weeks before radical prostatectomy, Intensive preoperative pelvic floor muscle training
- Where
- Hong Kong
- Volunteers
- 84 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Vitamin D Deficiency, 25-Hydroxyvitamin D Concentration
Is Vitamin D2 Treatment-associated Decrease in 25(OH)D3 Level a Reciprocal Phenomena?
Several studies have demonstrated that D2 treatment is associated with a decrease in 25(OH)D3 level and therefore have proposed that D3 would be preferable in term of raising total 25(OH)D level.
- Trial name
- NCT03035084
- Testing
- Vitamin D3, Vitamin D2
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Faisal Specialist Hospital & Research Center
COPD
Diaphragm Release Manual Technique Efficacy in COPD Patients
The aims of this study are to evaluate the effects of Diaphragm Release Manual Technique on diaphragm mobility, chest wall kinematics and functional capacity of COPD patients.
- Trial name
- NCT02212184
- Testing
- Manual Diaphragm Release Technique
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- Helga Cecília Muniz de Souza
Diabetes Mellitus, Type 2
Glufast On Insulin Glargine Trial in Type 2 DM
We will evaluate the efficacy and safety of combination therapy of 10 mg mitiglinide or 0.2mg voglibose with insulin glargine for 16 weeks after single administration of insulin glargine for 4 weeks in type 2 diabetic patients…
- Trial name
- GLORIA (NCT00663884)
- Testing
- Mitiglinide, Voglibose
- Where
- South Korea
- Volunteers
- 167 people
- Sponsor
- JW Pharmaceutical
Pain, Postoperative
Outcomes Of Perioperative Pregabalin On Total Knee Arthroplasty
This study aims to provide high quality evidence from a double-blinded, randomized controlled trial on the efficacy of perioperative pregabalin in reducing morphine requirements, improving pain scores and reducing chronic…
- Trial name
- NCT02954484
- Testing
- pregabalin, Etoricoxib, paracetamol
- Volunteers
- 116 people
- Sponsor
- National University Hospital, Singapore
Transcutaneous Electrical Nerve Stimulation, Urgent Urinary Incontinence
The Effectiveness of Parassacral Transcutaneous Stimulation Compared to Tibial Transcutaneous Stimulation, Home Protocol and Behavioral Therapy in the Treatment of Female Hyperative Bladder: Randomized Clinical Trial
Introduction: The overactive bladder is a highly prevalent condition, which negatively impacts the quality of life and daily activities of women.
- Conditions
- Transcutaneous Electrical Nerve Stimulation, Urgent Urinary Incontinence, Bladder Hyperactive, Women
- Trial name
- NCT04909047
- Testing
- parassacral transcutaneous electrostimulation
- Where
- 3 sites in Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centro de Atenção ao Assoalho Pélvico
Postnatal Growth Restriction, Necrotizing Enterocolitis
Human Milk-derived Fortification in Preterm Infants
Human Milk alone is unable to meet the high nutritional requirements of preterm infants. The American Academy of Pediatrics recommends fortification of human milk as a standard practice in all very low birth weight (VLBW)…
- Trial name
- NCT05228847
- Testing
- Human milk-derived HMF, bovine milk-derived HMF
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Calgary
Gingival Recession
Evaluation of Root Coverage After the Use of Coronally Advanced Flap Either With Advanced Paltelet Rich Fibrin or Subepithilial Connective Tissue Graft in Treatment of Miller Class I and II Gingival Recession.
patients with Miller class I , II gingival recession will be divided into 2 groups (control, intervention).the control one will receive coronally advanced flap with subepithililal connective tissue graft harvested from the palate…
- Trial name
- NCT03695549
- Testing
- CAF + (A-PRF), CAF+SCTG
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Cancer, Chemotherapy-induced Nausea and Vomiting
Efficacy and Safety of Intravenous Versus Oral 5-HT3 Antagonists Combined With NK-1 Receptor Antagonists for the Prevention of CINV in Breast Cancer
Chemotherapy is one of the most common treatments for breast cancer, but the adverse effects can be severe enough to delay or make chemotherapy intolerable, thus affecting the efficacy of the disease.
- Trial name
- NCT05841849
- Testing
- Aprepitant, Palonosetron, Fosaprepitant
- Where
- China
- Volunteers
- 1,028 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Obesity, Lumbar Spine Surgery
WoundVac in Obese Patients Undergoing Lumbar Surgery
This is an open label, randomized clinical trial of Closed-Incision Negative-Pressure Therapy to decrease post-operative wound complications in patients with BMI ≥35kg/m2 after posterior lumbar spine surgery.
- Trial name
- NCT03688438
- Testing
- Closed-Incision Negative-Pressure Therapy
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Norton Leatherman Spine Center
Cachexia, Lymphoma
Celecoxib in Managing Pain, Weight Loss, and Weakness in Patients With Advanced Cancer
RATIONALE: Celecoxib may help relieve moderate or severe pain associated with cancer. It may also decrease weight loss and improve muscle strength in cancer patients.
- Conditions
- Cachexia, Lymphoma, Melanoma (Skin), Ovarian Cancer
- Trial name
- NCT00093678
- Testing
- celecoxib, anticachectic therapy, nutritional support
- Sponsor
- Eastern Cooperative Oncology Group
Wrist Fractures
Early Functional Outcomes After Closed Reduction With Pinning Versus Open Reduction Internal Fixation of Wrist Fractures
The purpose of this study is to compare early return to function in patients treated with closed reduction percutaneous pinning and open reduction internal fixation in displaced fractures of the distal radius.
- Trial name
- NCT00828685
- Testing
- CRPP, ORIF
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
Myofascial Trigger Point Pain
Effects on Neuromuscular Function After Dry Needling in Myofascial Trigger Points in the Gastrocnemius Muscles
Trigger points (TrPs) are a common musculoskeletal cause of local and referred muscle pain, as well as local inflammation in the muscle and fascia.
- Trial name
- NCT04851743
- Testing
- Dry needling
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
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