Clinical trials: Randomized Controlled Trial, open to volunteers
Haemodialysis Patients, Laughter Yoga
Laughter Yoga Intervention in Patients on Haemodialysis
This study was planned as a randomized controlled experimental type and pre-test-post-test design in order to examine the effects of laughter yoga applied to hemodialysis patients on the happiness and mental well-being levels of…
- Trial name
- laughter yoga (NCT06938737)
- Testing
- laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Muğla Sıtkı Koçman University
Antipsychotic Induced Weight Gain
: EFFECT OF PROBIOTIC SUPPLEMENTATION ON ATYPICAL ANTIPSYCHOTIC INDUCED WEIGHT GAIN IN PATIENTS ATTENDING PSYCHIATRIC CLINICS AT AINSHAMS UNIVERSITY HOSPITALS (A RANDOMIZED CONTROLLED TRIAL)
the goal of the study is to improve the quality of life of patients on antipsychotic medications and increase the rate of compliance to treatment.
- Trial name
- NCT06936137
- Testing
- lactobacillus LS
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Parkinson's Disease (PD), Parkinson Disease 6, Early-Onset
Phase Ⅲ Clinical Trial to Evaluate the Efficacy and Safety of TJ0113 Capsules in Patients With Early-Onset Parkinson's Disease
This study is a randomized, double-blind, multicenter, placebo-controlled Phase III clinical trial designed to evaluate the efficacy, safety, and Pop PK characteristics of TJ0113 Capsules in treating EOPD patients.
- Trial name
- NCT07741045
- Testing
- TJ0113 200mg, TJ0113 400mg
- Where
- 21 sites in China
- Volunteers
- 300 people
- Sponsor
- Hangzhou PhecdaMed Co., Ltd.
Anxiety, Biliary Tract Diseases
Nurse-Led Education Before ERCP: Effects on Patient Knowledge and Anxiety
Endoscopic retrograde cholangiopancreatography (ERCP) is an invasive procedure frequently accompanied by preprocedural anxiety, which has been associated with altered physiological parameters, reduced procedural tolerance, higher…
- Conditions
- Anxiety, Biliary Tract Diseases, Pancreatic Diseases
- Trial name
- ERCP-EDU (NCT07805577)
- Testing
- Structured nurse-led preprocedural education, Routine information
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Breast Cancer
Effect of an Amino Acids and Flavonoids Containing FSMP on Chemotherapy Toxicity, Nutritional Status and Quality of Life in Breast Cancer Patients
The goal of this clinical trial is to compare the effect of a Food for Special Medical Purposes (FSMP) mainly containing amino acids and flavonoids in combination with nutritional counseling, versus nutritional counseling alone…
- Trial name
- NCT05968677
- Testing
- FSMP, Nutritional counseling
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Flavolife Srl
Chronic Apical Periodontitis
In Vivo Study on the Material Properties of iRoot SP and nRoot SP Root Canal Sealers
A randomized controlled trial was conducted to compare the treatment efficacy of iRoot SP and nRoot SP Root Canal Sealer Materials in patients with chronic apical periodontitis.
- Trial name
- NCT07388901
- Testing
- iRoot SP, nRoot SP
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Knee Pain Chronic, Knee Pain Swelling
Efficacy of Microparticle Geniculate Artery Embolization in Total Knee Prosthesis Patients With Pain Resistant to Medical Treatment. A Prospective Randomized Controlled Trial
The goal of this clinical investigation is to evaluate the effectiveness on pain of arterial occlusion (embolization) of neovessels by microparticle in a double-blind sham controlled randomised trial in patients with persistent…
- Trial name
- EPROGE (NCT06466330)
- Testing
- microparticles, embolization
- Where
- 11 sites in France
- Volunteers
- 112 people
- Sponsor
- Societe Francaise de Rhumatologie
IBD (Inflammatory Bowel Disease)
Efficacy of Melatonin Treatment on Sleep Quality Improvement in Inflammatory Bowel Disease Patients With Clinical Remission
Sleep disturbances are common in patients with inflammatory bowel disease (IBD) and are associated with increased disease activity and reduced quality of life.
- Trial name
- Melatonin IBD (NCT07737665)
- Testing
- Melatonin ("Circadin")
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Mahidol University
Cancer Pain, Virtual Reality Immersion
Enhancing Pain Management Among Patients Diagnosed With Stage III and Stage IV of Breast Cancer: The Power of Immersive and Non-Immersive Virtual Reality-Driven Interactive Guided Imagery
Cancer-related pain is one of the most common and distressing symptoms experienced by patients with advanced cancer, particularly among women diagnosed with advanced breast cancer.
- Trial name
- NCT07497451
- Testing
- Immersive Virtual reality guided imagery, VR (VR-Control)
- Where
- Jordan
- Volunteers
- 90 people
- Sponsor
- Middle East University
Lewy Body Dementia
Non-invasive Transcranial Focused Low-intensity Ultrasound Stimulation in Patients With Mild Lewy Body Dementia
A randomized controlled clinical study was conducted in the xuanwu hospital Single Center of Capital Medical University to preliminarily explore the efficacy and safety of transcranial focused low-intensity ultrasound stimulation…
- Trial name
- tFUS in DLB (NCT05499429)
- Testing
- Transcranial low intensity focused ultrasound stimulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Acute Ischemic, Medium Vessel Occlusion
INTRA-ARTERIAL MeVO TREATMENT (IMP-ACT) Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632
This domain will be conducted as part of ACT-GLOBAL platform trial and will have the nested domain name of IMP-ACT. Acute ischemic stroke (AIS) caused by intracranial arterial occlusion remains a major cause of disability and…
- Trial name
- IMP-ACT (NCT07906275)
- Testing
- Mechanical Endovascular Thrombectomy, Intravenous Thrombolysis, Tenecteplase/Alteplase- depending upon availability at each treating centre
- Where
- 4 sites in Canada
- Volunteers
- 800 people
- Sponsor
- University of Calgary
Undescended Testis, Anxiety State
The Effect of Using Multimedia During the Informed Consent Process on the Anxiety of Parents of Orchiopexy Patients
Aim: The goal of this randomized controlled trial is to detect the effect of using multimedia during the informed consent process on the anxiety of parents of orchiopexy patients.
- Trial name
- NCT06698081
- Testing
- Video Multimedia
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Marmara University
Hepatocellular Carcinoma
DEB-TACE With Visualable Microspheres Versus PVA Microspheres for HCC
This study will evaluate the safety and efficacy of DEB-TACE with visualable embolization microspheres versus PVA microspheres for hepatocellular carcinoma.
- Trial name
- NCT06190665
- Testing
- DEB-TACE with visualable microspheres, DEB-TACE with PVA microspheres
- Where
- 2 sites in China
- Volunteers
- 188 people
- Sponsor
- Zhongda Hospital
Stroke, Acute Ischemic
Intravenous rhTNK-tPA Before Stroke Thrombectomy in the Extended Time Window
This randomized, double-blind, placebo-controlled phase III clinical trial aims to evaluate the efficacy and safety of intravenous recombinant human tenecteplase (rhTNK-tPA) in acute ischemic stroke patients with large vessel…
- Trial name
- NCT06987305
- Testing
- Intravenous rhTNK-tPA, Endovascular thrombectomy
- Where
- 4 sites in China
- Volunteers
- 820 people
- Sponsor
- Xinqiao Hospital of Chongqing
Hepatitis B
Phase Ia/Ib Trial of SCTA02A Injection in Healthy Adults and Patients With Chronic Hepatitis B
Study SCTA02A-A101 is designed to assess the safety, tolerability and pharmacokinetics of SCTA02A in healthy volunteers and participants with chronic hepatitis B virus infection.
- Trial name
- NCT07903831
- Testing
- SCTA02A
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Implementation Science, Delirium
Behavioral Economic & Staffing Strategies in the ICU
The overarching goal of this study is to support the "real world" assessment of strategies used to foster adoption of several highly efficacious evidence-based practices in healthcare systems that provide care to critically ill…
- Conditions
- Implementation Science, Delirium, Critical Illness, Mechanical Ventilation Complication
- Trial name
- BEST-ICU (NCT06184945)
- Testing
- Realtime audit and feedback, RN Implementation Facilitator
- Where
- 3 sites in United States
- Volunteers
- 16,500 people
- Sponsor
- University of Nebraska
POSEIDON Category 4, Low Prognosis in Assisted Reproductive Technology
Impact of Day 2 Versus Day 3 Fresh Embryo Transfer on Live Birth Rate in Poor-Prognosis Patients
This study aimed to compare the efficacy (live birth rate) of fresh embryo transfer on Day 2 versus Day 3 in POSEIDON Group 4 patients, and to determine the optimal timing of embryo transfer for this population.
- Conditions
- POSEIDON Category 4, Low Prognosis in Assisted Reproductive Technology, Female Infertility Due to Diminished Ovarian Reserve
- Trial name
- NCT07533695
- Testing
- Day 2 Fresh Embryo Transfer
- Volunteers
- 470 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Accuracy of 3D Printed Titanium Plates Versus 3D Milled Titanium Plates in Genioplasty Orthognathic Surgery, Patient Specific Genioplasty
Accuracy of Patient Specific 3D Printed Titanium Plates Versus Milled Titanium Plates in Genioplasty Orthognathic Surgeries.
To assess accuracy of patient specific 3D printed titanium plates versus 3D milled titanium plates in genioplasty orthognathic surgery
- Conditions
- Accuracy of 3D Printed Titanium Plates Versus 3D Milled Titanium Plates in Genioplasty Orthognathic Surgery, Patient Specific Genioplasty, Accuracy of 3D Printed Titanium Plates Versus 3D Milled Titanium Plates in Genioplasty
- Trial name
- NCT07344441
- Testing
- genioplasty using 3D printed patient specific titanium plates (study group), genioplasty using 3D milled patient specific titanium plates (control group)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Neoplasm, Cancer
Using Artificial Intelligence to Guide Fluid Therapy During Major Cancer Surgery: A Randomized Controlled Trial
The goal of this clinical trial is to learn if using artificial intelligence to guide intravenous fluid therapy during major cancer surgery can help keep blood pressure more stable compared with usual care in adult patients…
- Conditions
- Neoplasm, Cancer, Hemodynamic (MAP) Stability, Cancer Surgery
- Trial name
- FOCUS-AFM (NCT07314853)
- Testing
- Artificial Intelligence-Assisted Fluid Management, Standard fluid management
- Where
- Italy
- Volunteers
- 176 people
- Sponsor
- National Cancer Institute, Naples
Sclerosis, Multiple, Neurocognitive Impairment, Mild
The DANCEREX Proof-of-Concept Study for Chronic Neurological Disorders
The goal of this clinical trial is to test a new digital therapeutic solution which combines a holistic, multidimensional rehabilitation program based on dance and music with an innovative motivational system (DANCEREX-DTx) in…
- Conditions
- Sclerosis, Multiple, Neurocognitive Impairment, Mild, Neurocognitive Dysfunction
- Trial name
- DANCEREX-DTx (NCT06112639)
- Testing
- DANCEREX-DTx, Multidimensional dance-based program, Educational Program
- Where
- 3 sites in Italy
- Volunteers
- 192 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
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