Clinical trials: Randomized Controlled Trial (RCT)
Post-operative Pain, Opioid Use
RCT of Counseling Intervention on Post-op Opiate Use
This study is a randomized controlled trial to investigate the effect of a simple counseling intervention on post-operative narcotic requirements, with the hypothesis that women receiving this intervention will use fewer…
- Conditions
- Post-operative Pain, Opioid Use, Cesarean Section
- Trial name
- NCT03359798
- Testing
- Narcotic counseling script, Post-partum depression counseling script
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Physical Inactivity, Sedentary Behavior
Cost-effectiveness, Impact of a Workplace-based Intervention to Reduce Occupational Sitting Time in Office-based Workers
The purpose of this study is to examine the impact and cost effectiveness of a workplace-based intervention aimed at reducing prolonged occupational sitting among office-based workers. The study will be conducted in three phases.
- Conditions
- Physical Inactivity, Sedentary Behavior, Occupational Diseases, Physical Activity
- Trial name
- ISKE (NCT06149364)
- Testing
- ISKE
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
IPV, HIV
Tu'Washindi RCT: Adolescent Girls in Kenya Taking Control of Their Health
This study will test the effectiveness of a youth-designed multilevel intervention, Tu'Washindi, to increase PrEP use and reduce intimate partner violence (IPV) among Kenyan AGYW and to identify implementation challenges and…
- Conditions
- IPV, HIV, PrEP
- Trial name
- NCT05599581
- Testing
- Tu'Washindi
- Where
- 2 sites in Kenya
- Volunteers
- 1,562 people, healthy volunteers welcome
- Sponsor
- RTI International
Alcohol Use Disorder
Testing the Efficacy of an Online Integrated Treatment for Comorbid Alcohol Misuse and Emotional Problems
Considering the high comorbidity between alcohol use disorders and emotional problems, there is currently a need for accessible, integrated treatments designed to target both disorders simultaneously.
- Trial name
- NCT03406039
- Testing
- Integrated Online CBT and MI
- Where
- Canada
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Substance Abuse, Intravenous, HIV
Change the Cycle: An RCT to Prevent Injection Initiation
The study will test the efficacy of a hour long, one-on-one, active listening counseling session (called Change the Cycle or CTC) aimed at reducing behaviors among active people who inject drugs (PWID) that research has found to…
- Conditions
- Substance Abuse, Intravenous, HIV, Heroin Dependence, Opioid Dependence
- Trial name
- CTC (NCT02774954)
- Testing
- Change the Cycle
- Where
- 2 sites in United States
- Volunteers
- 979 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Diarrhea
Meatsafe Food Storage and Diarrhea Prevention Trial in Urban Bangladesh
The goal of this clinical trial was to evaluate whether a simple household food storage cabinet called a "meatsafe" could reduce bacterial contamination of complementary foods and decrease diarrhea among children aged 6 to 24…
- Trial name
- NCT07332078
- Testing
- Meatsafe Food Storage Cabinet
- Where
- Bangladesh
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Dysmenorrhea
Effectiveness of ST With TENS and Stretching Exercises on Menstrual Pain and QOL With Dysmenorrhea. RCT
Effectiveness of somatocognitive therapy with TENS and stretching exercises on menstrual pain and quality of life with dysmenorrhea.A randomized controlled trial The objective of this study is to find weather which therapy…
- Trial name
- NCT07036913
- Testing
- somatocognitive therapy, Stretching exercises
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Superior University
HIV Prevention
Four-Arm Randomized Control Trial of Brief MI Versus Couples-Based HIV/STI Prevention in South Africa
This study is a Randomized Controlled Trial (RCT) of Integrated and Cognitive Behavioral Therapy for HIV Prevention in Pretoria, South Africa.
- Trial name
- SA R01 (NCT01554423)
- Testing
- Testing and Counseling, Brief Motivational Interview (BMI), Integrated Family and Cognitive Behavioral Therapy
- Where
- South Africa
- Volunteers
- 464 people, healthy volunteers welcome
- Sponsor
- The City College of New York
Mental Health Wellness 1, Positive and Negative Affect
Effects of a Relaxation and Guided Imagery Intervention in School Context
Specific aims - To test the effects of a relaxation and guided imagery intervention with socioemotional learning content on a range of socioemotional, physiological, cognitive and academic outcomes of school-aged children…
- Conditions
- Mental Health Wellness 1, Positive and Negative Affect, Social Skills, Happiness
- Trial name
- MR (NCT06101225)
- Testing
- MindRegulation Intervention, Relaxation, Waiting List Control Group
- Where
- Portugal
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidade Autónoma de Lisboa
Clinical Study - RCT
Paraspinal Stimulation in Treating MPS
To test the hypothesis that the effect of either multiple deep intramuscular stimulation therapy [(DIMMST: trigger point deep dry needling (TrP-DDN) is combined with paraspinal deep intramuscular stimulation (PDIMS) and needle…
- Trial name
- DIMMST (NCT01708343)
- Testing
- DIMMST
- Where
- 3 sites in Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cognitive Function
Nutrilite Memory Builder on the Improvement of Cognitive Function
Its a randomized controlled trial, to evaluate the effect of NUTRILITE Memory Builder on the improvement of cognitive function in middle-aged and elderly people.
- Trial name
- NCT05591885
- Testing
- Study product group (Nutrilite Memory Builder)
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amway (China) R&D Center
Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke
RCT of HeartBot in Women
The goal of this clinical trial is to find out whether an app-based program called HeartBot II, which uses an artificial intelligence (AI) chatbot, can help improve women's awareness and knowledge of heart attacks in women.
- Conditions
- Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke, Participants Should Have no Terminal Illness or Diagnosed Cognitive Impairment, Including Alzheimer's Disease, Participants Should Not be a Healthcare Professionals or Healthcare Trainees
- Trial name
- HeartBot II (NCT07416734)
- Testing
- HeartBot II Program, Waitlist Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anxiety, Depressive Symptoms
StriveWeekly Online Mental Health Trial Post-pandemic
With the COVID-19 pandemic completely altering the landscape of higher education, students have been experiencing more stress than ever.
- Conditions
- Anxiety, Depressive Symptoms, Stress, Emotional
- Trial name
- NCT04927845
- Testing
- StriveWeekly
- Where
- United States
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- Harvard University
Tooth Loss, Dental Implant, Single-tooth
RCT of BLT Implants Used for Immediate vs Early Placement, Restored With Ceramic Crowns on Titanium Bonding Bases.
The purpose of this study is to assess the outcome of a new bone level tapered implant when inserted either following an immediate placement protocol or an early placement approach and restored with single crowns out of two…
- Trial name
- BLT (NCT05079542)
- Testing
- Timepoint of Implant placement of Bonelevel tapered implants, Material for tooth restoration - Lithiumdisilicate glass ceramic or zirconia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Vitamin D Deficiency
Inter-relationship Between Vitamin D Requirements and Calcium Intake in Older Adults
This winter-based placebo-controlled, single-dose vitamin D randomized controlled trial (RCT) aims to examine the impact of various levels of habitual calcium intake on dietary vitamin D requirements in older adults stratified by…
- Trial name
- VitD-Ca (NCT01990872)
- Testing
- Vitamin D3 (20 micrograms/day)
- Where
- Ireland
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University College Cork
Safety Issues, Infant Nutrition Disorders
Clinical Evaluation of a Low Protein Content Formula in the First Months of Life: a RCT
This study aimed to evaluate the tolerance and safety of a low-protein formula in healthy full-term infants by investigating effects on growth and gastrointestinal tolerance and by identifying any adverse effects.
- Trial name
- NCT03035721
- Testing
- Low protein formula, Standard protein formula
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Anterior Cruciate Ligament (ACL) Reconstruction
Gabapentin Premedication for ACL Reconstruction: RCT
This double blind randomized control trial will enroll 100 participants ages 12-18 years, undergoing ACL repair. Participants receive gabapentin or placebo preoperatively.
- Trial name
- NCT03417479
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Chromosomal Abnormalities
Preimplantation Genetic Screening in Women of Advanced Maternal Age
An increased incidence of aneuploid pregnancies has been reported in women of advanced maternal age, with higher miscarriage rates.
- Trial name
- NCT00795795
- Testing
- Preimplantation Genetic Screening, IVF without PGS
- Where
- Spain
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Patient-centered Care
Impact of a Wellness Portal on The Delivery of Patient-Centered Preventive Care
Building upon our experience with a very sophisticated preventive services prompt and reminder system, the Preventive Services Reminder System (PSRS), the investigators propose to conduct a systematic three-year study with the…
- Trial name
- NCT01520662
- Testing
- Implementation of a secure web-based patient Wellness Portal
- Where
- United States
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Lower Limb Amputation
A Pilot RCT to Investigate the Use of a Home-based Nintendo Wii Program for Rehabilitation in Older Adults With Lower Limb Amputation
This is a pilot randomized controlled trial to assess the feasibility of a home-based Nintendo Wii Fit program (Wii.n.Walk) to improve walking capacity in older adults with a lower limb amputation.
- Trial name
- NCT01715662
- Testing
- Wii.n.Walk, Wii Big Brain
- Where
- 3 sites in Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of British Columbia