Clinical trials: Randomized Controlled Trial (RCT)
Screening for Partner Violence
Computer-assisted Screening for Intimate Partner Violence in Family Practice
This study tested the effectiveness of computer-assisted screening for identifying patients at risk of intimate partner violence (IPV) in a Canadian family practice.
- Trial name
- NCT00385034
- Testing
- Interactive computer based health-risk survey before doctor's visit
- Where
- Canada
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Colorectal Neoplasms
Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)
Adenoma detection rate (ADR) is a quality indicator of colonoscopy performed for colorectal cancer screening. Population studies have shown that traditional air colonoscopy fails to eliminate post screening colonoscopy cancers or…
- Trial name
- NCT01607255
- Testing
- Indigo carmine, water (exchange) method, water (exchange) plus dye method
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Chromosomal Abnormalities
Preimplantation Genetic Screening in Women of Advanced Maternal Age
An increased incidence of aneuploid pregnancies has been reported in women of advanced maternal age, with higher miscarriage rates.
- Trial name
- NCT00795795
- Testing
- Preimplantation Genetic Screening, IVF without PGS
- Where
- Spain
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Gastrointestinal Tolerance, Gastrointestinal Symptoms
Gastrointestinal Symptoms and Tolerance in Infants Fed Goat or Cow's Milk-based Infant Formula
This randomized controlled double-blind study will compare the effect of a commercially available goat milk formula to a cow's milk formula on gastrointestinal symptoms and tolerance, and infections in infants.
- Conditions
- Gastrointestinal Tolerance, Gastrointestinal Symptoms, Infections, Quality of Life
- Trial name
- MESK-2 (NCT07342972)
- Testing
- Goat milk-based infant formula, Cow's milk-based infant formula
- Where
- Saudi Arabia
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Substance Abuse, Intravenous, HIV
Change the Cycle: An RCT to Prevent Injection Initiation
The study will test the efficacy of a hour long, one-on-one, active listening counseling session (called Change the Cycle or CTC) aimed at reducing behaviors among active people who inject drugs (PWID) that research has found to…
- Conditions
- Substance Abuse, Intravenous, HIV, Heroin Dependence, Opioid Dependence
- Trial name
- CTC (NCT02774954)
- Testing
- Change the Cycle
- Where
- 2 sites in United States
- Volunteers
- 979 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Heart Rate, All-day Steps
Assessing the Effect of Cool Roofs on Health Using Smartwatches
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate…
- Conditions
- Heart Rate, All-day Steps, Distance Walked, Active Minutes
- Trial name
- REFLECT (NCT06579963)
- Testing
- Cool roof
- Where
- 4 sites in Burkina Faso, India and 2 more
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Gingival Phenotype
Comparison of Microneedling and CTG for Gingival Augmentation- A RCT
The presence study is toComparison of Microneedling with Subepithelial Connective Tissue Auto Graft for Gingival Augmentation- A Randomized Case Control Trial.
- Trial name
- NCT06060119
- Testing
- microneedling
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Gastric Cancer
The Effect of Post-operative Exercise in Gastric Cancer Patients: A Randomized Controlled Trial (RCT) Study
Medical advancements are enhancing the survival rates of individuals with gastric cancer. The growing population of gastric cancer survivors underscores the importance of managing treatment-related after-effects and side effects.
- Trial name
- NCT06260293
- Testing
- exercise
- Where
- South Korea
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Dental Caries in Children
Evaluation of New Different Herbal Mouthwashes Against Caries Forming Bacteria, RCT
The goal of this randomized controlled trial is to compare three different types of mouthwash, Moringa, Star anis, and Indian Costus 90 children participated in this study divided into 3 groups according to the type of mouthwash…
- Trial name
- NCT05623605
- Testing
- Moringa mouthwash, star anise mouthwash, Indian costus mouth wash
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Nahda University
PTSD
Psychological First Aid (PFA): RCT Adults Non-intentional Trauma Emergency Room
Psychological First Aid (PFA) is currently the most recommended early intervention for people affected by recent traumatic events, especially in the aftermath of natural disasters.
- Trial name
- PFA (NCT02608086)
- Testing
- Psychoeducation, Psychological First Aid
- Where
- 5 sites in Chile
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Twin Pregnancy, Antepartum Condition or Complication
Effects of ACS in Twin With LPB: Study Protocol for a RCT
This study will be the first study that evaluates the effectiveness of antenatal corticosteroid (ACS) in late preterm twin neonates.
- Trial name
- NCT03547791
- Testing
- Betamethason Sodium Phosphate, Normal saline
- Where
- South Korea
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Metabolic Syndrome, Obesity
An Exercise RCT Targeting African-American Women With Metabolic Syndrome and High Risk for Breast Cancer
Among African-American women, in whom metabolic syndrome (MetS) is very prevalent and breast cancer mortality rates are high, it is hypothesized that intervening on MetS to improve the MetS profile may prove to be a means to…
- Trial name
- NCT02103140
- Testing
- Facility-based Exercise, Home-based Exercise
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Georgetown University
HPV Vaccination, Uptake Vaccination
PREVENT HPV -Related Cancers Trial
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Uptake Vaccination, Series Completion
- Trial name
- NCT07217145
- Testing
- PREVENT
- Where
- United States
- Volunteers
- 1,455 people, healthy volunteers welcome
- Sponsor
- University of Utah
Hysterectomy
RCT Superior Hypogastric Block During LH
The goal of this study is to assess the efficacy of a superior hypogastric plexus block (SHPB) for pain relief following a laparoscopic hysterectomy.
- Trial name
- NCT03283436
- Testing
- Bupivacaine Hydrochloride 0.25% Injection Solution
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jon I. Einarsson
Teeth, Endodontically-Treated, Tooth, Nonvital
Comparison Between RCT in Single and Two Visits, With and Without Intracanal Dressing, in Apical Repair
This is a randomized, prospective, double-blind, controlled clinical trial designed to evaluate 3 distinct clinical approaches used during endodontic therapy: Group 1- Root canal treatment in single visit (RCT-SV); Group 2- Root…
- Conditions
- Teeth, Endodontically-Treated, Tooth, Nonvital, Periapical Periodontitis, Chronic Nonsuppurative, Periapical Granuloma
- Trial name
- NCT05256667
- Testing
- RCT-SV, RCT-TVWD, RCT-TVWOD
- Where
- Brazil
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- New York University
Women Who Are Aged 18-49 Years, Able to Read, Write
Reducing Endocrine-Disrupting Chemical Exposure in Reproductive-Age Women: A Pender Model-Based RCT
Abstract Background: Endocrine-disrupting chemicals (EDCs) are widely encountered in daily life and may adversely affect reproductive health.
- Conditions
- Women Who Are Aged 18-49 Years, Able to Read, Write, Voluntarily Agree to Participate in the Study
- Trial name
- NCT07773233
- Testing
- Intervention Group
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Harran University
Mode of Delivery, Pelvic Floor Dysfunction
A RCT to Evaluate the Effects of Pelvic and Abdominal Mechanical Exercises During Pregnancy on Reducing the Rate of CS and Preventing PFD
Pelvic floor dysfunction diseases seriously affect the quality of life. Childbirth, especially vaginal birth, is significantly related to pelvic floor dysfunction diseases, which mainly cause urinary incontinence and pelvic organ…
- Trial name
- NCT05252455
- Testing
- pelvic and abdominal mechanics exercise
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Qiu Jin
Caregivers, Community Health Workers
Intervention to Help Orient Men to Excel (IN-HOME) Phase II Study
The goal of the study is to examine the effect of outreach from IN-HOME-trained CHWs on changes in male informal caregiver knowledge/skills, positive attitudes, self-efficacy, and intentions about caregiving topics.
- Conditions
- Caregivers, Community Health Workers, Knowledge, Attitude
- Trial name
- IN-HOME (NCT07704060)
- Testing
- Intervention to Help Orient Men to Excel (IN-HOME), Supplying Useful Perimenopause Through Post-menopause Online Resources and Tools (SUPPORT)
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- KDH Research & Communication
Prosthesis Survival
Implant Retained CAD-CAM Ceramic Crowns
Newly available ceramic CAD-CAM blocs containing a screw channel for chairside-made crowns to be adhesively cemented to a TiBase abutment and screw-retained to an implant are appealing to the clinician, considering the time…
- Trial name
- RCT-Scherrer (NCT04773873)
- Testing
- PFM Crowns on gold coping cast-on, hybrid abutment lithium disilicate crown, hybrid abutment ceramic polymer infiltrated crown
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Susanne Scherrer
Perineal Trauma, Ritgen Maneuver
Ritgen Maneuver and Birth-Related Perineal Trauma: RCT
Perineal trauma is one of the common complications that may occur during the second stage of labor and can negatively affect women's postpartum recovery and quality of life.
- Trial name
- NCT07713173
- Testing
- Ritgen maneuver, Routine Care Group
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medipol University