Clinical trials: Randomized Controlled Trials
Mental Health
Evaluation of the Gambling Habits of Adolescents and Young Adults Post-COVID-19 and Implementation of a Digital Escape Room Intervention for Preventing Gambling in High School Students
Gambling behaviors among adolescents and young adults have been experiencing an upward trend in the last years, possibly because of new habits developed during the COVID-19 lockdown restrictions.
- Trial name
- NCT06904794
- Testing
- GAMBL-OUT program
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Hospital Miguel Servet
Erectile Dysfunction
Pelvic Floor Muscle Training in the Treatment of Erectile Dysfunction
Erectile dysfunction affects about 40% of all men above the age of 40 and the prevalence increases with increasing age. It is not possible to cure the condition as current forms of treatment are aimed solely at improving…
- Trial name
- NCT05385822
- Testing
- Pelvic Floor Muscle Training
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Healthy Older Adults
Effect of Dual Task in Aquatic Physical Therapy in Older Adults
Population ageing is associated with declines in motor and cognitive functions, which compromise autonomy and increase the risk of falls and cognitive impairment.
- Trial name
- NCT07270094
- Testing
- Aquatic Dual-Task Training, Conventional Aquatic Exercise
- Where
- Portugal
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Instituto Politécnico de Leiria
Dysbiosis
Effect of Probiotic on Gut Microbiome and Bacterial Translocation in Healthy Asian Volunteers
Dysbiosis of the gut microbiome has been recognized to underlie the pathogenesis of various gastrointestinal conditions. Probiotics are known to exert beneficial effects on gut health and have great potential for use as…
- Trial name
- NCT05083572
- Testing
- Colonic lavage with polyethylene glycol, Probiotic, Antibiotic
- Where
- Singapore
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Autism Spectrum Disorder, Parents
Virtual Reality Experiences as Tools to Support Mental Health in Parents of Children With Autism
Mindfulness is a technique that involves the intentional and non-judgmental regulation of attention to the present moment, with curiosity, openness, and acceptance, as per its definition.
- Trial name
- Mind-VR (NCT05852795)
- Testing
- Virtual Reality-mediated Mindfulness-Based Interventions, Virtual Reality-mediated Mindfulness-Based Interventions without audio guided experience
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Patellofemoral Pain Syndrome
Treatment Effects on Neuromuscular Properties on Young Women Symptomatic for Patellofemoral Pain Syndrome
Patellofemoral Pain Syndrome (PFPS) is characterized by diffuse pain around the knee joint. This presence of pain is the most common manifestation in sports medicine among adults and young people.
- Trial name
- NCT03663595
- Testing
- Model 1, Model 2
- Where
- Brazil
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Mediastinal Neoplasms, Thoracic Neoplasm
Pain and Quality of Life After Mediastinal Tumor Resection by Subxiphoid and Intercostal VATS
Thoracoscopic assisted mediastinal thymectomy is currently one of the most commonly used surgical methods, but there are some deficiencies.Minimally invasive surgery through the subxiphoid approach can achieve a good surgical…
- Conditions
- Mediastinal Neoplasms, Thoracic Neoplasm, Thoracic Surgery
- Trial name
- NCT03521986
- Testing
- Subxiphoid uniportal VATS, Intercostal uniportal VATS
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lei Jiang
Obesity
Laser Acupuncture Versus High Protein/Low Carbohydrate Diet on Endothelial Markers in Obese Females
The purpose of this study is to compare the effects of laser acupuncture and high protein low carbohydrate diet on the treatment of obesity and lowering of endothelial markers.
- Trial name
- NCT02573961
- Testing
- Laser acupuncture, high protein low carbohydrate diet, low caloric diet
- Where
- Egypt
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Anesthesia, Local
Compare the Efficacy of Various Pain Alleviating Methods in Reducing Pain in Children During Intraoral Local Anaesthetic Injections
The aim of study is to compare the efficacy of various pain alleviating methods by application of Emla gel, TENS, and topical cooling of injection sites compared with 20% benzocaine gel in reducing pain in children requiring…
- Trial name
- NCT05564442
- Testing
- 20% benzocaine gel, Transcutaneous electric nerve stimuli, Emla gel
- Where
- Egypt
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Minia University
Childhood Obesity, Childhood Obesity Pevention
Effectiveness of School-Based Time-Restricted Eating for the Prevention and Control of Obesity in Children
Childhood obesity has become a major global public health challenge. Obesity can not only affects children's physical and mental health during childhood but may also persist into adulthood, significantly increasing the risk of…
- Trial name
- SCHOOL-TRE (NCT07184281)
- Testing
- 12-hour time-restricted eating, health education
- Where
- 2 sites in China
- Volunteers
- 1,380 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Soochow University
Electrocardiography, Clinical Competence
Storyline-Based Gamified Blended Learning for ECG Interpretation in Nursing Students
The goal of this randomized controlled trial is to determine whether a Storyline-based gamified blended learning (SGBL) intervention improves electrocardiogram (ECG) interpretation competence and self-reported clinical…
- Trial name
- SGBL-ECG (NCT07857369)
- Testing
- Storyline-based Gamified Blended Learning, Conventional Face-to-Face Instruction
- Where
- Iran
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Qom University of Medical Sciences
Calcaneus Fracture
Minimally Invasive Calcaneal Fracture Fixation vs Standard Lateral Approach
a comparison between the standard lateral extensile approach and minimally invasive sinus tarsi approach in this research.
- Trial name
- NCT04509895
- Testing
- Lateral extensile approach in calcaneal fractures fixation, Minimally invasive sinus tarsi approach in calcaneal fractures fixation
- Where
- Egypt
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Assiut University
Wound Healing
Clinical Efficacy of a Chlorhexidine-based Mouth-rinse Containing Citrus Aurantium Amara
The primary objective of the study is the evaluation of efficacy of a mouthwash cointaining Chlorexidine (CHX) 0.09% + HA + Citrox (test group) on the quality of wound healing and the presence plaque formation and gingival…
- Trial name
- CUR_01 (NCT06738342)
- Testing
- CHX 0.09% + Citrox + HA, CHX 0.12%
- Where
- Italy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Lethal Means Safety, Brief Intervention
Testing Family Firearm Secure Storage Training (FFAST) to Prevent Suicide
Firearms are the lethal means used in over 70% of Veteran suicides with rates of Veteran deaths via self-induced firearm injury rising dramatically (by 64.8%) from 2001 to 2022.
- Conditions
- Lethal Means Safety, Brief Intervention, Concern Significant Others
- Trial name
- FFAST RCT (NCT07692854)
- Testing
- The Family Firearms Secure storage Training (FFAST) Intervention, Health and Stress Counseling
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Plaque Induced Gingival Disease, Oral Health
Effect of Benzydamine Hydrochloride Mouthrinse on Plaque Accumulation in Periodontally Healthy Female Subjects
The goal of this clinical trial is to evaluate the effect of a mouthrinse containing an active ingredient benzydamine hydrochloride in the absence of daily oral hygiene.
- Trial name
- BHCl-PLAQUE (NCT07565766)
- Testing
- Benzydamine hydrochloride mouthrinse
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Medical Education, Medical Training
Adapting Web-based Instruction to Baseline Knowledge of Physicians-in-training
The purpose of this study is to compare an adaptive Web-based learning system to a non-adaptive system for teaching physicians-in-training about ambulatory medicine.
- Conditions
- Medical Education, Medical Training, Internship and Residency
- Trial name
- NCT00466453
- Testing
- knowledge-adaptive Web-based instruction
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Wound Infection
To Assess Use of Vancomycin Powder in Craniotomy on Wound Infection Rates
Surgical site infection (SSI) after craniotomy is a major cause of morbidity and mortality besides its major health care cost. In each hospital, all measures are taken to decrease SSI.
- Trial name
- NCT04917627
- Testing
- Vancomycin
- Where
- Qatar
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hamad General Hospital
Postpartum Constipation
Effect of Electroacupuncture on Bowel Function and Quality of Life in Postpartum Constipation: A Randomized Controlled Trial
Postpartum constipation is a common condition affecting women after childbirth, leading to discomfort and reduced quality of life. Pharmacological treatments may have side effects and are sometimes avoided during breastfeeding.
- Trial name
- NCT07572786
- Testing
- electroacupuncture, abdominal exercises for constipation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- MTI University
Multiple Sclerosis
Effects of Reiki and Self-Acupressure Applications
Reiki, the subject of our research, is a complementary medicine practice within energy approaches. Discovered in Sanskrit texts by Dr.
- Trial name
- NCT07083856
- Testing
- Reiki, Self-Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Firat University
Forensic Nursing Education in Pediatric Nurses, Forensic Competency Training
Forensic Nursing Education for Pediatric Nurses
This randomized controlled trial aims to evaluate the effect of structured forensic nursing education on pediatric nurses' forensic competency.
- Trial name
- FOREN-NURSE (NCT07519239)
- Testing
- Forensic Nursing Education
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dicle University