Clinical trials: Randomized Controlled Trials
Type 2 Diabetes, Exercise
Effects of Nordic Walking and Exercise on Glucose Metabolism in Type 2 Diabetes Mellitus: A Randomized Controlled Trial
The objective of this randomized controlled trial was to evaluate the effects of two different physical exercise programs aimed at long-term lifestyle changes in physical activity in patients with Type 2 Diabetes, with glucose…
- Trial name
- NCT01085773
- Testing
- Exercise on Prescription, Nordic Walking
- Where
- Denmark
- Volunteers
- 68 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Warts
Intralesional Vitamin D Injection for Treatment of Common Warts
Researchers are trying to find out if injecting Vitamin D into a wart is an effective treatment.
- Trial name
- NCT04278573
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Stephen P. Merry
Acute Upper Respiratory Tract Infection, Bacterial Infections
A Cluster Randomized Controlled Trial to Compare the Rate of Antibiotic Infusion
Acute upper respiratory tract infection, commonly known as upper respiratory infection, is an acute inflammation primarily affecting the nose, pharynx, or larynx caused by various viruses and/or bacteria.
- Trial name
- NCT06620341
- Testing
- drug education
- Where
- China
- Volunteers
- 11,900 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Radiology, Medical Errors
AI-Based Quality Control for Radiology Reporting
The goal of this clinical trial is to learn whether an artificial intelligence (AI)-based radiology report quality-control system can improve the accuracy and workflow efficiency of routine radiology reporting among active…
- Trial name
- NCT07865741
- Testing
- Radiology Report GPT (AI-Based Radiology Report Quality-Control System)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Lymphoma
EFFECT OF A 16-SESSION QIGONG PROGRAM ON PHYSICAL AND MENTAL HEALTH IN PATIENTS WITH LYMPHOMA: A RANDOMIZED CONTROLLED TRIAL
The aim of the present study was to investigate in lymphoma patients the effects of a 16-session qigong programme (2 times a week) on physical and psychological parameters.
- Trial name
- NCT04701554
- Testing
- Qigong program, Information on healthy lifestyles, physical exercise and dietary recommendations.
- Where
- Spain
- Volunteers
- 39 people
- Sponsor
- Consuelo Lourdes Díaz Rodríguez
Weight Gain
Efficacy of Olanzapine on Weight Gain in Advanced Gynecologic Cancer with Paclitaxel and Carboplatin: a Double Blind, Placebo-controlled Randomized Trial
Efficacy of olanzapine on weight gain in advanced stage gynecologic cancer Proprotion of pateints in advanced stage gynecologic cancer who recieving paclitaxel and carboplatin chemotherapy gain weight on olanzapine or placebo
- Trial name
- NCT06288854
- Testing
- weight gain each group
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Mental Health Wellness
Two Recovery Strategies at Work, Based on Mindfulness and Physical Exercise, on Levels of Stress and Biological Measures
The present study aims to compare the differential effects of mindfulness meditation (MBI) and physical exercise (PE) on different stress and health variables (self-report means and IgA and cortisol levels).
- Trial name
- ERME2 (NCT05557266)
- Testing
- Mindfulness-based intervention, Physical exercise
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidad Nacional de Educación a Distancia
Uterine Fibroid
Efficacy of Paracervical Block in Laparoscopic Myomectomy: a Randomized Controlled Trial (PALM)
It remains controversial whether paracervical block should be performed as a powerful strategy for pain relief in laparoscopic myomectomy (LM), because convincing conclusions are difficult to draw because of the heterogeneous and…
- Trial name
- PALM (NCT04068766)
- Testing
- Paracervical block, 5% bupivacaine, Normal saline
- Where
- 2 sites in South Korea
- Volunteers
- 62 people
- Sponsor
- Kangbuk Samsung Hospital
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial
Spinal cord injury (SCI) results in lower limb muscle loss, bone loss, and high fat mass that impede the recovery of physical function, increase bone fracture risk, and worsen health and quality of life.
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Injuries, Spinal Cord, Spinal Cord Contusion
- Trial name
- TRT-SCI (NCT07742553)
- Testing
- testosterone cypionate, finasteride
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- VA Office of Research and Development
Autism
Interactive Massage Intervention in Toddlers With Autism Spectrum Disorder
This randomized controlled trial aims to evaluate the efficacy of a 3-month maternal interactive massage intervention in toddlers aged 18-24 months with autism spectrum disorder (ASD).
- Trial name
- IMI-ASD (NCT07876245)
- Testing
- Maternal Interactive Massage, Behavioral
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Endoscopic Submucosal Dissection, Endoscopic Submucosal Dissection (ESD)
The Improvement Effect of Real-time Artificial Intelligence Assisted Identification of Bleeding Points on Hemostasis Efficiency in Endoscopic Submucosal Dissection
The goal of this clinical trial is to learn if an artificial intelligence (AI) system that identifies bleeding points in real time can help stop bleeding faster during endoscopic submucosal dissection (ESD) - a minimally invasive…
- Trial name
- NCT07495137
- Testing
- AI real-time assistance in endoscopic submucosal dissection (ESD) for bleeding spot identification and marking
- Volunteers
- 160 people
- Sponsor
- Qilu Hospital of Shandong University
Depression
Personalized Prevention of Depression in the Workplace (e-pD-Work)
The main goal is to design, develop and evaluate a personalized intervention to prevent depression in the workplace, based on Information and Communication Technologies (ICTs), predictive risk algorithms and decision support…
- Trial name
- e-pD-Work (NCT04858737)
- Testing
- e-predictD-Work intervention, Brief psychoeducational messages
- Where
- Spain
- Volunteers
- 1,054 people
- Sponsor
- The Mediterranean Institute for the Advance of Biotechnology and Health Research
Healthy
Influence of an Osteopathic Treatment Protocol on the Improvement of Sleep Quality in Young Adults With Insomnia
Sleep deprivation, which is a universal necessity, has serious physiological consequences. Sleep disorders are among the most common health problems, and yet they are often neglected.
- Trial name
- NCT05899972
- Testing
- Suboccipital inhibition technique, Frontal lift technique, Parietal lift technique
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Urinary Incontinence
Effects of Osteopathic Manipulations and Muscle Training on the Myoelectric Activity of the Pelvic Floor
The objective of this study was to compare the effects of four different interventions on pelvic floor muscle electromyographic activity in women with stress urinary incontinece: i) a global osteopathic protocol (myofascial…
- Trial name
- NCT04584359
- Testing
- HVLA, global osteopathic protocol, pelvic floor muscle training
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Giselle Notini Arcanjo
Diabetes Mellitus (Type 2)
Empowering Veterans to Actively Communicate and Engage in Shared Decision Making in Medical Visits, A Randomized Controlled Trial
Type 2 diabetes is a significant condition in VA affecting 20% of VA patients. Adherence to medication regimens and lifestyle factors is important to achieve care goals for these patients.
- Trial name
- ACTIVet-2 (NCT05169359)
- Testing
- Speak Up! Video
- Where
- 3 sites in United States
- Volunteers
- 512 people
- Sponsor
- VA Office of Research and Development
Breast Reconstruction
Comparing Two Different Surgical Techniques for Breast Reconstruction
The purpose of this study is to compare two standard techniques for breast reconstruction-the prepectoral technique and the subpectoral technique.
- Trial name
- NCT04716959
- Testing
- Prepectoral Prosthetic Breast Reconstruction, Subpectoral Prosthetic Breast Reconstruction
- Where
- 7 sites in United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Acute Myeloid Leukemia (AML)
Venetoclax, Azacitidine, and Mitoxantrone Hydrochloride Liposome Versus Idarubicin and Cytarabine in Newly Diagnosed AML
This study aims to evaluate the efficacy and safety of venetoclax combined with azacitidine and mitoxantrone hydrochloride liposome (MVA) versus idarubicin combined with cytarabine (IA) in the treatment of newly diagnosed AML.
- Trial name
- NCT07486479
- Testing
- Mitoxantrone Hydrochloride Liposome, Venetoclax, Azacitidine
- Where
- 21 sites in China
- Volunteers
- 204 people
- Sponsor
- The First Affiliated Hospital of Soochow University
First Episode Psychosis (FEP)
Self-administered COgnitive Personalized Training in Early Psychosis
The overall objective of SCOPe is to improve early intervention in psychosis by providing an innovative eHealth tool that will enable personalized cognitive training, adapted to the individual's cognitive abilities.
- Trial name
- SCOPe (NCT06634446)
- Testing
- a mobile application for cognitive training, video games
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Smoking and POCD
The Effect of Heavy Smoking on Early Post Operative Cognitive Dysfunction in Senile Patients .
Cognitive dysfunction is the impairment of mental process of perception, memory and information processing which allow the human to acquire knowledge and plan for the future .
- Trial name
- NCT05782946
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Beni-Suef University
Extremely Deep Caries, Pulpitis
Effectiveness of Pulpotomy vs. Root Canal Treatment in Extremely Deep Caries
Recent clinical trials comparing pulpotomy versus root canal treatment (RCT) have shown promising outcomes; however, the current evidence lacks generalisability to general practitioners.
- Trial name
- NCT07242742
- Testing
- Full Pulpotomy, root canal treatment and intracanal medicament
- Where
- Singapore
- Volunteers
- 93 people
- Sponsor
- National University Hospital, Singapore