Clinical trials: Randomized-controlled Trial
Healthy Participants
A Study of STAR-0310 in Healthy Adult Participants
This is a randomized, double-blind, placebo-controlled, single ascending dose trial evaluating the safety, tolerability, PK, and immunogenicity of STAR-0310 in healthy adult participants.
- Trial name
- NCT06782477
- Testing
- STAR-0310
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Astria Therapeutics, Inc.
Malnutrition
Optimal Amount of Zinc to Include in a Lipid-based Nutrient Supplement (LNS)
To assess zinc-related biochemical and functional responses among young Burkinabe children with a presumed high risk of zinc deficiency who receive micronutrient products containing different amounts of zinc, provided with or…
- Trial name
- NCT00944281
- Testing
- LNS-Zn5, LNS-Zn10, LNS-Zn0
- Where
- Burkina Faso
- Volunteers
- 3,220 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Microbial Colonization
Restoration of the Gut Microbiome After Cesarean Section
This study aims to develop a therapy for restoring the gut microbiome in infants born via CS. The Study will conduct a randomized, placebo-controlled feasibility trial to assess the ability of microbiome restoration by FMT and…
- Trial name
- RestoreGut (NCT06264219)
- Testing
- Microbiome restoration - FMT, Microbiome restoration - FVT, Vaginal birth, untreated control
- Where
- 2 sites in Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jakob Stokholm
Physical Fitness, Cognitive Function
Effects of a 12-Week Dance Intervention on Physical Fitness and Cognitive Function in Female College Students
This study aimed to examine the effects of a 12-week dance intervention on physical fitness and cognitive function in female college students.
- Trial name
- NCT07769411
- Testing
- 12-Week Dance Intervention, Regular Physical Education
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Jiangsu University of Science and Technology
Memory Disorders, Anxiety Depression
Coriandrum Sativum Seeds Improve Memory, Alleviate Anxiety and Depression, and Enhance Sleep Quality in University Students: A Randomized Controlled Trial
C. sativum could potentially serve as a memory enhancer for university students. It is considered a preferable option to stimulant drugs due to its safety profile. Additionally, C.
- Conditions
- Memory Disorders, Anxiety Depression, Sleep
- Trial name
- NCT05999071
- Testing
- Coriandrum sativum seeds
- Where
- Jordan
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
IVF Cycle, Ovarian Stimulation
Efficacy and Safety of Medication Used to Stimulate Ovulation
Individuals undergoing In Vitro Fertilization must undergo controlled ovarian hyperstimulation (COH) to produce enough quality eggs for fertility treatment.
- Conditions
- IVF Cycle, Ovarian Stimulation, Egg Retrieval, Pregnancy
- Trial name
- NCT02715336
- Testing
- Ovulation induction with hCG and Lupron (GnRH agonist)
- Where
- Canada
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- Create Fertility Center
Anxiety
40-Hz Audiovisual Stimulation in Schizophrenia Spectrum Disorders
This randomized, sham-controlled trial evaluated the effects of 40-Hz binaural beat music (BBM) combined with 40-Hz rhythmic photic stimulation (RPS) in adults with schizophrenia spectrum disorders.
- Trial name
- NCT07782034
- Testing
- 40-Hz Binaural Beat Music Combined With 40-Hz Rhythmic Photic Stimulation
- Where
- Taiwan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Vertigo, Diseases, Vestibular
Effect of Caffeine Intake in Vestibular Function
Objective: Assess the effect of caffeine in the following vestibular function tests: Cervical Vestibular Evoked Potential (cVEMP), Ocular Vestibular Evoked Potential(oVEMP) and Caloric Test.
- Conditions
- Vertigo, Diseases, Vestibular, Caffeine
- Trial name
- NCT02825199
- Testing
- Caffeine, Non caffeine
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Instituto Brasiliense de Otorrinolaringologia
Pulpal Necrosis
Single-file Pulpectomy in Primary Molars
The current study evaluates the rotational One Shape single-file system regarding clinical and radiographic outcomes in root canal treatment of infected primary molars.
- Trial name
- NCT04394702
- Testing
- One Shape Single-file rotary system, manual stainless steel K-file
- Where
- Egypt
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Minia University
COVID-19
Phase II Clinical Trial of COVID-19 mRNA Vaccine in Adults Aged 18 Years and Older
To evaluate the safety and immunogenicity of COVID-19 mRNA vaccine in people aged 18 years and older, 300 participants will be enrolled and divided into two groups: low- and high-dose groups.
- Trial name
- NCT05373472
- Testing
- COVID-19 mRNA vaccine
- Where
- 3 sites in China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Healthy Participants Study
ACT-based EMI in College Students
This study aims to evaluate the acceptability and effectiveness of a transdiagnostic, Acceptance and Commitment Therapy (ACT)-based ecological momentary intervention (EMI) among college students.
- Trial name
- NCT06843395
- Testing
- ACT-based ecological momentary intervention, Mood monitoring
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Carcinoma, Hepatocellular
Associating Liver Partition With Portal Vein Ligation For Staged Hepatectomy (ALPPS) or Portal Vein Occlusion in Treating Patients With Liver Cancer
This randomized phase II trial compares how well associating liver partition with portal vein ligation for staged hepatectomy (ALPPS) or portal vein occlusion (PVO) works in treating patients with liver cancer.
- Trial name
- ALPPS (NCT01722175)
- Testing
- ALPPS surgery, PVO surgery
- Volunteers
- healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Colorectal Cancer
Colorectal Cancer Screening Among Primary Care Physicians of the Swiss Sentinel Surveillance Network
Colorectal cancer (CRC) is the third leading cause of cancer mortality in Switzerland, and kills 1600 people annually. Most deaths could be prevented by screening, but the 2012 Swiss national health survey found that only 40% of…
- Trial name
- NCT03552744
- Testing
- Mailed training intervention
- Where
- Switzerland
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Bern
Education Curriculum
Different Re-training Durations in BLS Training Among Non-Professionals
Previous studies on compression-only CPR and AED training for the general public have primarily focused on the optimal retraining interval. However, the impact of different retraining durations remains unclear.
- Trial name
- NCT06867653
- Testing
- Retraining
- Where
- Taiwan
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Oral Mucositis
Effect of Cold Application and Artificial Saliva in the Prevention of Chemotherapy-Induced Oral Mucositis
the Objectives of this clinical trial is : 1. To determine the effect of Cold Application for preventing of chemotherapy-Induced oral mucositis in cancer patients. 2.
- Trial name
- NCT07297472
- Testing
- cold application, Artificial Saliva
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karbala University
H1N1 Influenza Virus, Invasive Solid Tumors
Clinical Trial to Compare the Immunogenicity, Safety, and Tolerability of an Adjuvanted A(H1N1) Influenza Vaccine Versus Non-Adjuvanted A(H1N1) Influenza Vaccines in Patients With Invasive Solid Tumors
This is a phase III, randomized, controlled, open label study with two vaccine regimens. The study will assess the relative safety and immunogenicity of vaccine regimens comparing adjuvanted versus non-adjuvanted formulations of…
- Trial name
- NCT01031719
- Testing
- adjuvanted A(H1N1) influenza vaccine, non-adjuvanted A(H1N1) influenza vaccine
- Where
- 3 sites in Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Chiltern Pesquisa Clinica Ltda
Altitude Hypoxia
Effect of Acetazolamide on Lung Water Content by Ultrasound in Lowlanders Older Than 40 Years at Altitude
Randomized, placebo controlled trial evaluating the effect of acetazolamide on lung water content by ultrasound in lowlanders older than 40 years travelling from 760 m to 3'100 m.
- Trial name
- NCT03539367
- Testing
- ACETAZOLAMIDE oral capsule
- Where
- Kyrgyzstan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Sinus Floor Augmentation, Maxillary Sinus Floor Elevation
Evaluation of Lateral Sinus Floor Elevation Using Xenograft Versus L-PRF Block Combined With Xenograft
Rehabilitation of the posterior maxilla with dental implants is frequently complicated by insufficient residual bone height resulting from alveolar ridge resorption and maxillary sinus pneumatization.
- Conditions
- Sinus Floor Augmentation, Maxillary Sinus Floor Elevation, Sinus Lift, Xenograft
- Trial name
- NCT07677007
- Testing
- Lateral sinus lift with Xenograft Alone, Lateral sinus lift using L-PRF Block + Xenograft
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Distal Radius Fractures, Wrist Fracture
Unstable Distal Radius Fractures With Dorsal Dislocation in Patients Aged 18-64 Years. Volar Locking Plate (VLP) vs Closed Reduction and Percutaenous Pinning (CRPP).
120 patients age 18-64 years with dorsally displaced distal radius fractures AO-type A2, A3 and C1 are recruited from Oslo Casualty Medical Centre (Oslo Skadelegevakt).
- Conditions
- Distal Radius Fractures, Wrist Fracture, Colles' Fracture
- Trial name
- NCT04716309
- Testing
- Open reduction and volar locking plate and closed reduction and K-wires.
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Ketosis, Acute-Phase Response
Metabolic Effects of Whey Protein Supplementation After Fasting in Volunteers
This study aims to investigate the early metabolic effects and acute phase response of an oral clear supplement containing whey protein plus carbohydrates in young healthy volunteers during fasting-induced organic response
- Conditions
- Ketosis, Acute-Phase Response, Insulin Resistance
- Trial name
- NCT05656339
- Testing
- CHO+WP, CHO, Fast
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Mato Grosso
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