Clinical trials: Randomized-controlled Trial
Nonceliac Gluten Sensitivity
Dose-finding Gluten Challenge Trial in Nonceliac Gluten-sensitivity
An emerging problem in clinical practice is how to manage the growing number of patients who experience symptoms related to the ingestion of gluten-containing foods gluten and in whom celiac disease has been ruled out.
- Trial name
- RAPLAGE (NCT03188367)
- Where
- Italy
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Antonio Di Sabatino
Adolescent Behavior, Adolescent Problem Behavior
Yoga on Stress Management in Adolescents
The World Health Organization (WHO, 2013) defined the 10-19 age group as "adolescent" and the 15-24 age group as "youth". Adolescence period; It is a period of rapid growth, development and maturation in terms of physical…
- Trial name
- NCT05324709
- Testing
- Yoga Based Stress Management Program
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Hypocalcemia
Preoperative Vitamin D for Post-thyroidectomy Hypocalcemia
The purpose of this study is to determine if pre-operative vitamin D supplementation lowers the incidence of post-operative transient or permanent hypoparathyroidism in patients undergoing total thyroidectomy.
- Trial name
- NCT01609439
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Smoking Cessation
Quitxt Mobile Text Messaging Cessation Research Study
The health benefits of smoking cessation by age 30 are much greater than cessation later in life, including gaining 10 years of life, compared with those who continue to smoke.
- Trial name
- NCT05958667
- Testing
- Quitxt text messaging or Chat, Usual care
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Oral Mucositis Due to Chemotherapy
Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients
The goal of this clinical trial is to evaluate the efficacy of propolis in the prevention of oral mucositis and reducing pain score in children undergoing chemotherapy, and assessing its impact on body mass index, pediatric…
- Trial name
- NCT07073092
- Testing
- propolis, chlorohexidine mouthwash and topical antifungal
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Mental Health
Cocreation and Evaluation of an Escape Game on Students' Mental Health
The Covid-19 pandemic and the protracted lockdowns have heavily impacted university students' mental health. Digital Escape Games represent a good means to reach students and propose them solutions for their psychological…
- Trial name
- EscapeCovid (NCT06720792)
- Testing
- EscapeCovid
- Where
- France
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Vaginal Personal Care
Randomized, Double-blind, Placebo-controlled Trial Investigating the Role of a Personal Care Product on Vaginal Health
The goal of this clinical trial is to assess the impact of a personal care product on vaginal health in a healthy participant population.
- Trial name
- NCT05659745
- Testing
- VM-02, Commercial Oral Probiotic Competitor
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Seed Health
Depression
Competency-based Training in Problem Management Plus: a Randomized Controlled Trial
The proposed study in Nepal will evaluate if non-specialists participating in Equip-based Problem Management Plus training show greater competencies compared to non-specialists participating in standard Problem Management Plus…
- Trial name
- EQUIP-PM+ (NCT04954872)
- Testing
- Standard Problem Management Plus training (training as usual), Equip-based Problem Management Plus training
- Where
- Nepal
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- George Washington University
Textile Worker
Exercise Program Combined With Ergonomic Training in Textile Workers
Most studies in the literature focus on musculoskeletal disorders and pain levels in occupational groups with repetitive workloads, such as textile workers.
- Trial name
- NCT07408401
- Testing
- Supervised Exercise, Home exercise
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Okan University
Dental Caries in Children
Effectiveness of Silver Diamine Fluoride in Arresting Dental Caries
The present study aims to evaluate, through a controlled clinical randomized study,the effectiveness of silver diamine fluoride in arresting dentin caries lesions in primary molars when compared to atraumatic restorative…
- Trial name
- NCT03063307
- Testing
- Atraumatic Restorative Treatment, Silver Diamine Fluoride
- Where
- Brazil
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Surveys and Questionnaires, Noncommunicable Diseases
Use of Airtime Timing to Improve Interactive Voice Response Surveys in Bangladesh and Uganda
This study evaluates the effect of two different airtime incentive timings on interactive voice response (IVR) survey cooperation, response, refusal and contact rates, as compared to a control group, in Bangladesh and Uganda.
- Trial name
- NCT04513236
- Testing
- Pre-survey incentive, Post-survey incentive
- Where
- 2 sites in Bangladesh, Uganda
- Volunteers
- 2,287 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Abdominal Obesity
Effect of Ultrasound Cavitation Versus Whole Body Vibration on Abdominal Fat in Obese Adolescent Females
This study aims to determine the differences between the effect of ultrasound cavitation and whole-body vibration on abdominal fat in obese adolescent females
- Trial name
- NCT06529211
- Testing
- Low caloric diet, Ultrasound cavitation, Whole body vibration
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cancer Survivors, Return to Work
Enhancing Work Participation of Unemployed and Work-Disabled Cancer Survivors
The primary objective of this study is to evaluate the effectiveness of the PLACES intervention on paid employment re-entry in unemployed and work-disabled cancer survivors, compared to CAU.
- Trial name
- PLACES (NCT06028048)
- Testing
- PLACES
- Where
- 2 sites in Netherlands
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Infection, Pregnancy
Effects of Oral Probiotic Supplementation on Group B Strep (GBS) Rectovaginal Colonization in Pregnancy
The investigators wish to determine if oral probiotic supplementation during the second half of pregnancy decreases maternal GBS recto-vaginal colonization at 35-37 weeks' gestational age, thereby decreasing need for maternal…
- Trial name
- NCT01479478
- Testing
- Probiotic dietary supplement
- Where
- 3 sites in United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Stanford University
Motor Learning
Improving Locomotor Learning With Brain Stimulation
The primary goal of this research was to assess the practicality and initial effectiveness of a motor imagery (MI) intervention combined with elements of action observation (AO), alongside active or sham transcranial direct…
- Trial name
- ELLMITS (NCT06414213)
- Testing
- Motor Imagery (MI), Active tDCS
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
COVID-19
A Randomized Controlled Trial Assessing the Efficacy of Lianhua Qingwen as an Adjuvant Treatment in Patients With Mild Symptoms of COVID-19
COVID-19 virus remains in infected patients for extended periods of time. A great resource burden is placed on the healthcare system and society at large to isolate COVID-19 patients for prolonged periods.
- Trial name
- NCT04433013
- Testing
- Lianhua Qingwen
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Hemodynamic Response to Laryngoscopy and Orotracheal Intubation
Effect of Nalbuphine on Hemodynamic Response During Laryngoscopy and Intubation
Laryngoscopy and placement of a breathing tube during general anesthesia can cause temporary increases in blood pressure and heart rate. These changes may be harmful in some patients.
- Trial name
- NAL-HRI (NCT07348159)
- Testing
- Normal saline IV, Nalbuphine 0.2 mg/kg
- Where
- Pakistan
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Dr. Waseem Ullah
Postural Kyphosis, Hyperkyphosis
Innovative Orthosis in Hyperkyphosis
Thoracic hyperkyphosis is a common postural deformity; however, the optimal treatment strategy has yet to be clearly defined. This randomized controlled trial aimed to assess the effectiveness of an innovative three-dimensional…
- Trial name
- NCT06988046
- Testing
- Cover spine orthosis (CSO), Semi-rigid thoracolumbar orthosis
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Periapical Diseases, Periapical Periodontitis
Effect of Targeted Endodontic Microsurgery on Quality of Life and Healing on Mandibular Molars
Targeted endodontic microsurgery represents precise and advanced approach to resolving persisting chronic periapical periodontitis after non- surgical root canal treatment.
- Conditions
- Periapical Diseases, Periapical Periodontitis, Periapical Cyst, Periapical Granuloma
- Trial name
- NCT06643676
- Testing
- Targeted Endodontic Microsurgery Using 3d Printed surgical guide using the patient's CBCT data, Conventional Endodontic Microsurgery with a free hand procedure using bur and CBCT analysis
- Where
- India
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Autism Spectrum Disorder
Individualized Parent-Based Nutrition Education in Preschool Children With Autism Spectrum Disorder
Feeding difficulties, such as food selectivity and refusal to try new foods, are common among preschool children with autism spectrum disorder (ASD).
- Trial name
- NCT07884097
- Testing
- Individualized Parent-Based Nutrition Education Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Firat University
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