Clinical trials: Randomized-controlled Trial
Healthy Volunteers, Health Promotion
Dance-Mindfulness Intervention for Well-Being in Recreational Adults
This 12-week study protocol outlines a randomized controlled trial designed to evaluate the effectiveness of a Dance-Mindfulness intervention integrating Modern Theatre Dance with mindfulness-based embodied practices to enhance…
- Trial name
- DanceMind (NCT07262177)
- Testing
- Dance-Mindfulness Intervention
- Where
- Greece
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Burnout Syndrome, Psychological Distress
Web-based ACT to Support Parents With Children With Chronic and Developmental Conditions
Parents of children with a chronic disease or functional disabilities have an increased risk of stress-related distress and reduced quality of life.
- Conditions
- Burnout Syndrome, Psychological Distress, Depressive Symptoms, Quality of Life
- Trial name
- Uupu (NCT04250012)
- Testing
- Internet-based ACT intervention, Psychoeducation
- Where
- Finland
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Contraceptive Usage, Telemedicine
Telemedicine Contraceptive Counselling (TECC) Versus Standard Care
Overall purpose of the PILOT and RCT: This research project aims to increase access and uptake of contraception after abortion through the systematic development and testing of a new telemedicine service for contraceptive…
- Trial name
- TECC (NCT06682065)
- Testing
- Telemedicine for contraceptive counseling (TECC), Standard Care
- Where
- 2 sites in South Africa
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Physical Health, Mental Health
MVP RCT: Mind and Voice Project Randomized Control Trial
The study seeks to learn more about the health behaviors of young adults. Health behaviors include relationships, physical and mental health, alcohol use, and conflicts with others.
- Conditions
- Physical Health, Mental Health, Alcohol; Use, Problem, Interpersonal Violence
- Trial name
- NCT04018807
- Testing
- Resource pamphlet, Remote Therapy
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Medical Education
Artificial Intelligence-Integrated BOPPPS Case-Based Learning for Nephrology Clerkship Education
This prospective, three-arm, parallel-group, cluster randomized controlled educational trial was conducted among third-year undergraduate medical students undertaking nephrology clerkship at The Second Hospital of Shandong…
- Trial name
- NCT07820137
- Testing
- Lecture-Based Learning, BOPPPS Combined With Case-Based Learning, AI-Integrated BOPPPS Combined With Case-Based Learning
- Where
- China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Shandong University
Aging
Slow Age: Interventions to Slow Aging in Humans
The proportion of older individuals is growing, and it is therefore important to investigate ways to promote healthy aging. Exercise is one of the most studied interventions and is known to have a variety of health benefits.
- Trial name
- SlowAge (NCT05593939)
- Testing
- Exercise, Time restricted feeding, Nicotinamide riboside
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Periodontal Regeneration, Clinical and Radiographic Results, Modified Minimal Invasive Surgery
Evaluation of Healing of Intra-bony Defects in Modified Minimal Invasive Surgical Technique
This study is aiming to compare the clinical and radiographic outcomes after complete versus incomplete removal of granulation tissue during modified minimally invasive surgical technique for management of periodontal intrabony…
- Trial name
- NCT03562039
- Testing
- M-MIST
- Where
- 2 sites in Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pneumococcal Infectious Disease
Clinical Trial of PCV24 in Children Aged 2-17 Years
A Phase Ia clinical trial of 24-valent pneumococcal conjugate vaccine (PCV24) developed by Sinovac Life Science Co., Ltd will be conducted in children aged 2-17 years.
- Trial name
- NCT06550830
- Testing
- Sinovac PCV24 formulation 1, Sinovac PCV24 formulation 2, Prevenar13®
- Where
- China
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Sinovac Life Sciences Co., Ltd.
Colorectal Cancer, Cancer Screening
Social Media for Colorectal Cancer Screening
Using social media for health promotion is an innovative and emerging approach but remains relatively unexplored in cancer screening.
- Trial name
- NCT04296630
- Testing
- Social media message #1, Social media message #2, Social media message #3
- Where
- Canada
- Volunteers
- 56,000 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Surgery, Trauma
A Randomized Controlled Trial of a Video Decision Making Aid to Obtain Informed Consent in the Surgical Intensive Care Unit
To demonstrate that clinical surrogates of SICU patients who view a video decision aid in addition to receiving written and verbal information about procedures and life sustaining therapy in the SICU make more informed decisions…
- Trial name
- NCT01589107
- Testing
- video decision aid
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Blood Loss During Vaginal Hysterectomy
Comparison of the Effects of Cervical Vasopressin Versus no Premedication on Blood Loss During Vaginal Hysterectomy: A Randomized, Placebo Controlled Trial
Vasoconstrictive agents are increasingly being used in order to decrease blood loss during vaginal hysterectomy. The first reported study of the use of a vasoconstrictive agent for this purpose was on the use of epinephrine…
- Trial name
- NCT00799292
- Testing
- Vasopressin
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ascher-Walsh, Charles, M.D.
Erectile Dysfunction
Low-Intensity Extracorporeal Shock Wave Treatment for Erectile Dysfunction: A Randomized, Controlled, Double Blind Trial
The proposed mechanism of action for LI-ESWT in ED is that it improves endothelial function and triggers angiogenesis through induction of local growth factors and endothelial nitric oxide synthase.
- Trial name
- NCT03006536
- Testing
- Li-ESWT
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Colonoscopy
Time Interval After Gastric Emptying and Quality of Bowel Cleansing
The goal of this [clinical trial] is to [explore the balance time point between the waiting time for intestinal preparation after gastric emptying and quality of bowel preparation.] in [patients with painless colonoscopy].
- Trial name
- NCT06111937
- Testing
- after ultrasound gastric assessment to ensure gastric empty, painless colonoscopy was performed within 2 hours
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Dyslipidemia
Effect of Eggplant Extract on Lipid Profile During Fasting and Postprandial Period
The purpose of this study was to assess the effect of eggplant extract capsules on the lipid profile of healthy individuals after an oral lipid overload test in a randomized, double-blind, placebo-controlled clinical trial.
- Trial name
- NCT00845637
- Testing
- Eggplant extract
- Where
- Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Suicidal Ideation
Digital Narrative Bibliotherapy as a Scalable Intervention for Suicidal Thoughts
The goal of this study was to determine whether reading about others' experiences with suicide can help reduce suicidal thoughts. To investigate this issue, the investigators recruited users from an internet support community.
- Trial name
- NCT05351645
- Testing
- Treatment
- Where
- United States
- Volunteers
- 864 people, healthy volunteers welcome
- Sponsor
- Harvard University
Peri-Implant Mucositis, Peri-implantitis
Impact of an AI-Based Chatbot on Implant Patient Management: RCT
Background: Dental implant therapy is a well-established and predictable procedure for replacing missing teeth, with high long-term survival rates.
- Conditions
- Peri-Implant Mucositis, Peri-implantitis, Peri-Implant Health, Peri-implant Inflammation
- Trial name
- NCT07300657
- Testing
- AI Chatbot, Standard Oral Hygiene Education
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Catania
Human Immunodeficiency Virus (HIV), Sexually Transmitted Disease (STD)
Steering Together in a New Direction: Reducing the Risk of HIV/STD Among African American Men
African American men have by far the highest rates of HIV in the US, but there are few randomized controlled trials (RCTs) of interventions to dissuade heterosexually active African American men from engaging sexual risk…
- Trial name
- STAND (NCT02572401)
- Testing
- STAND HIV Risk Reduction Intervention, Text Messaging Intervention
- Where
- United States
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Functional Constipation
Lactobacillus Reuteri in Adult With Functional Chronic Constipation
A double-blind, placebo Randomized Controlled Trial, To evaluate the effects of L. reuteri in adult patients with functional constipation.
- Trial name
- NCT01870700
- Testing
- lactobacillus reuteri
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Catholic University, Italy
Furcation Defects
Platelet Rich Fibrin+1.2% Atorvastatin in Treatment of Mandibular Degree II Furcation Defects
The present study was designed to explore the effectiveness of PRF combined with 1.2% ATV gel in treatment of mandibular degree II furcation defects in comparison to PRF and open flap debridement (OFD) alone.
- Trial name
- NCT02612792
- Testing
- Open flap debridement (OFD), OFD with Platelet rich fibrin (PRF), OFD with Platelet rich fibrin (PRF)+1.2% Atorvastatin (Drug) in gel form
- Where
- India
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Vitamin D Deficiency
Nutritional Requirements for Vitamin D in Pregnant Women
Randomised, placebo-controlled dose-response intervention study with vitamin D3 in pregnant women.
- Trial name
- DMAT (NCT02506439)
- Testing
- 10 mcg Vitamin D3, 20 mcg Vitamin D3
- Where
- 2 sites in Ireland
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University College Cork
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