Clinical trials: Randomized-controlled Trial
Tuberculosis Infection
Immunization With BCG Vaccine to Prevent Tuberculosis Infection
The purpose of this research is to find out if a single dose of pre-travel vaccination with BCG can lessen tuberculosis (TB) infection by producing an immune response when given to adults traveling to countries with a high or…
- Trial name
- TIPI (NCT04453293)
- Testing
- BCG (Tokyo 172) vaccine
- Where
- 7 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Dental Restoration
Comparative Clinical Evaluation of BioFlx, Zirconia, and Stainless-Steel Crowns in Primary Molars
This study will be conducted to: Evaluate and compare the clinical success, periodontal changes, and wear of antagonist teeth for three types of prefabricated crowns in primary molars: BioFlx crowns, Zirconia crowns, and…
- Trial name
- NCT06450093
- Testing
- Preformed stainless steel crown., Preformed zirconia crown, Preformed BioFlx crown
- Where
- Egypt
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Breast Diseases
Effect of Peppermint Water on Breast Crack
To evaluate the effectiveness of a topical preparation of peppermint water in comparison with that of expressed breast milk for the prevention of nipple cracks in primiparous breastfeeding women.
- Trial name
- NCT00456404
- Testing
- peppermint water
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Tabriz University
Distal Radius Fracture
Randomized Controlled Trial Assessing the Effect of Dexamethasone on Postoperative Function After Distal Radius Fixation
The study is designed to assess the use of intraoperative dexamethasone on postoperative analgesia and stiffness after open reduction and internal fixation of distal radius fractures.
- Trial name
- NCT04889547
- Testing
- Dexamethasone, No dexamethasone
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Insomnia, Insomnia Chronic
Assessment of Sleep Quality and Mental Health After Using Meditation
This is a randomized controlled trial that intends to verify the effectiveness of the daily practice of meditation before going to sleep for the improvement of sleep, stress, mental health and quality of life of people with sleep…
- Conditions
- Insomnia, Insomnia Chronic, Insomnia Disorder, Sleep Disorder
- Trial name
- NCT05812443
- Testing
- Shabad Kriya Meditation, Relaxing reading
- Where
- Brazil
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Sleep
The Effectiveness of a Proprietary of a Botanical Extract on Sleep Quality
The purpose of this study is to evaluate the efficacy and superiority of a botanical based sleep product on sleep quality as compared to melatonin, among healthy female participants.
- Trial name
- NCT06894108
- Testing
- Proprietary Blend of Botanical Extracts, Melatonin
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Gonorrhea, Chlamydia
Pay-it-forward Gonorrhea and Chlamydia Testing Among Men in China
PIONEER is a three-arm, programmatic cluster randomized controlled trial (RCT) to compare effectiveness of three implementation strategies, followed by a mixed-methods implementation evaluation study
- Trial name
- NCT05723263
- Testing
- Standard Pay-it-forward, Community Engaged Pay-it-forward, Control arm
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy Young Soccer Players
Efficacy of FIFA 11+ Kids Injury Prevention Program on Soccer-specific Skills Among Young Soccer Players
Background: Soccer is a prevalent sport worldwide; most soccer players are under 18. Soccer has benefits for your health, but there is also a chance that you could get injuries occasionally.
- Trial name
- NCT06501833
- Testing
- FIFA 11+ KIDS PROGRAM, REGULAR TRAINING
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Infertility, IVF
Health of Frozen Transferred Versus Fresh Transferred Children
In order to give strong recommendation on the efficacy and safety of fresh versus frozen embryo transfer, we conduct this study in order to investigate the physical and mental development of children from fresh versus frozen…
- Trial name
- NCT04099784
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Physical Activity, Life Style
Cardiovascular Disease Prevention Strategies for High-risk Urban Sedentary Employees in Karachi, Pakistan
Heart diseases and other non-communicable diseases are serious health issues in countries like Pakistan. Many people who work in offices, like bank employees, sit for more than 8 hours a day.
- Conditions
- Physical Activity, Life Style, Dietary Habits, Cardiovascular Diseases
- Trial name
- m-LIfE (NCT06981247)
- Testing
- m-LIfE: mobile based lifestyle intervention for employees to increase their physical activity and promote healthy diet., Routine care arm
- Where
- Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Nasopharyngeal Cancer, Screening
Cluster Randomized Controlled Screening Trial for NPC
This study is aimed to estimate the effectiveness of an Epstein-Barr virus (EBV) serology-based screening program to reduce nasopharyngeal carcinoma (NPC) mortality in a cluster randomized controlled trial in an NPC high-risk…
- Conditions
- Nasopharyngeal Cancer, Screening, Morality
- Trial name
- CRCSTNPC (NCT00941538)
- Testing
- Experimental: Screening with EBV VCA/EBNA1-IgA testing
- Where
- 2 sites in China
- Volunteers
- 87,600 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Heart Failure, Acute Kidney Injury
Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome
The overall objective of this study is to determine whether the addition of SGLT2 inhibitors to usual care in hospitalized patients with heart failure associated acute kidney injury is safe and efficacious.
- Trial name
- NCT07273838
- Testing
- Dapagliflozin 10mg Tab
- Where
- 2 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy, Diaphragm Issues
Efficacy of the Transverse Planes Technique in the Diaphragmatic Region in Young Subjects.
In the present study, 28 healthy young people will be selected, who will be evaluated by a blind investigator regarding the study objectives, and will be randomly included in two groups.
- Trial name
- NCT05787626
- Testing
- manipulation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Gingivitis
Mouthwashes During Orthodontic Treatment
The number of orthodontic treatment provided to Brazilian population has been increased. Unfortunately, some negative effects such as gum bleeding and bad breath are commonly observed.
- Trial name
- MOUORT (NCT03179735)
- Testing
- Essential oils, Cetylpyridinium Chloride 0.7 mg/ml
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Taubate
Socket Sealing, Free Gingival Graft
Clinical and Histological Assessment of Free Gingival Graft or Collagen Matrix for Socket Sealing After Bone Grafting
The goal of this study was to compare, clinical and histologically, the use of the suine collagen matrix (Mucograft Seal [MS], Geisthlich®) and the free gingival graft (FGG) for the alveolar sealing after inserted bone graft…
- Conditions
- Socket Sealing, Free Gingival Graft, Collagen Membrane
- Trial name
- NCT05448040
- Testing
- Socket preservation
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade Salgado de Oliveira
Loneliness, Fear of Missing Out
Social Media Diet and Psychological Outcomes in University Students
This study aims to examine the effect of a social media diet intervention on loneliness, fear of missing out (FoMO), and sleep quality among university students.
- Conditions
- Loneliness, Fear of Missing Out, Sleep Quality
- Trial name
- The Effect of (NCT07473791)
- Testing
- Social Media Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Herpes Zoster, Varicella Zoster
Safety, Tolerability, and Immunogenicity of CRV-101 in Healthy Adult Subjects
The purpose of this clinical trial is to evaluate the safety, tolerability, and immunogenicity of vaccine candidate CRV-101, investigational vaccine in healthy adult subjects in the United States.
- Trial name
- NCT03820414
- Testing
- CRV 101
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Curevo Inc
Dental Caries, Dental Occlusion
Occlusal Impact of Hall Crowns in Primary Molars
Hall Technique is a non-invasive restorative approach for managing carious primary molars, increasingly used in pediatric dentistry due to its simplicity and patient tolerance.
- Conditions
- Dental Caries, Dental Occlusion, Pediatric Dentistry
- Trial name
- NCT07134114
- Testing
- Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Dental Anxiety
The Effect of Aromatherapy for First Dental Visit Patients
First dental visit experience is strongly correlated with dental anxiety, the aim of this protocol is to explore the efficacy of olfactory aromatherapy for the reduce of dental anxiety and pain in first-visit patient.
- Trial name
- NCT06598904
- Testing
- Aroma diffuser with single-note lavender essential oil, Aroma diffuser with single-note orange essential oil, Aroma diffuser with deionized water
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sichuan University
Respiratory Syncytial Virus Infections
Study of the Safety and Immunogenicity of an Intranasal Vaccine for Respiratory Syncytial Virus in Seropositive Children
This study evaluates an investigational vaccine that is designed to protect humans against infection with respiratory syncytial virus (RSV) and is administered as drops in the nose.
- Trial name
- NCT04444284
- Testing
- Investigational RSV vaccine MV-012-968 (Dosage 1), Investigational RSV vaccine MV-012-968 (Dosage 2), Investigational RSV vaccine MV-012-968 (Dosage 3)
- Where
- 3 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Meissa Vaccines, Inc.
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