Clinical trials: Randomized-controlled Trial
Malaria
Chloroquine for Malaria in Pregnancy
The purpose of this study is to test prevention strategies for pregnancy-related malaria. Researchers will compare different malaria treatments and treatment schedules which include chloroquine therapy (weekly doses versus being…
- Trial name
- NCT01443130
- Testing
- Chloroquine, Sulfadoxine-pyrimethamine
- Where
- Malawi
- Volunteers
- 900 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Type 2 Diabetes, Self-management
The Effect of Telephone Consulting on HbA1 and Self-Management
The aim of this study was to investigate the effect of telephone counseling (12 weeks) based on the Information, Motivation, Behavioral Skills (IMB) Model in patients with type 2 diabetes mellitus (T2DM) on self-management and…
- Trial name
- NCT04723628
- Testing
- Intervention group (telephone counseling)
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Aksaray University
Hot Flashes
Clinical Trial Assessing Toxicity and Efficacy of MF101 for Hot Flashes
The researchers propose a Phase II randomized, double-blind, placebo-controlled trial of 180 healthy postmenopausal women experiencing at least 5 hot flashes per day or 35 hot flashes per week.
- Trial name
- NCT00119665
- Testing
- MF101
- Where
- 4 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bionovo
IBD (Inflammatory Bowel Disease)
Efficacy of Melatonin Treatment on Sleep Quality Improvement in Inflammatory Bowel Disease Patients With Clinical Remission
Sleep disturbances are common in patients with inflammatory bowel disease (IBD) and are associated with increased disease activity and reduced quality of life.
- Trial name
- Melatonin IBD (NCT07737665)
- Testing
- Melatonin ("Circadin")
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Mahidol University
Acute Medical Patients Hospitalized in Internal Medicine
Decrease the Frequency of Inappropriate Intravenous Lines in Internal Medicine
Aim: to determine whether a nationwide teaching program delivered to medical doctors can decrease the use of inappropriate intravenous lines in internal medicine
- Trial name
- PERMI (NCT01633307)
- Testing
- Education
- Volunteers
- 59 people
- Sponsor
- Hopital Lariboisière
Gastric Cancer
Clinical Trials for the Prevention of Gallstone Formation After Gastrectomy in Patient With Gastric Cancer
This study evaluates the efficacy and safety of DWJ1319 in the prevention of gallstone formation after gastrectomy in patient with gastric cancer.
- Trial name
- NCT02490111
- Testing
- DWJ1319
- Where
- 12 sites in South Korea
- Volunteers
- 521 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Purpura, Thrombocytopenic, Idiopathic
High-dose Dexamethasone Versus Conventional Dose Prednisone for Initial Treatment of Primary Immune Thrombocytopenia (ITP)
The project was undertaking by Qilu Hospital of Shandong University and other 11 well-known hospitals in China. In order to report the efficacy and safety of high-dose dexamethasone compared to conventional dose prednisone for…
- Trial name
- NCT01356511
- Testing
- Prednisone, Dexamethasone
- Where
- China
- Volunteers
- 261 people
- Sponsor
- Shandong University
Primary Disease Facioscapulohumeral Dystrophy (FSHD)
Effects of NMES on Muscle Function of Patients With FSHD: a Double-blind Randomized Controled Clinical Trial
Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant disease characterized by progressive weakness and atrophy of specific skeletal muscles.
- Trial name
- NEMS and FSHD (NCT02861911)
- Testing
- Current flow between sensory and motor threshold, Current intensity upper of motor threshold by Kneehab XP technology
- Where
- France
- Volunteers
- 9 people
- Sponsor
- University Hospital, Montpellier
Acupuncture, Mild Traumatic Brain Injury
Acupuncture for Mild Traumatic Brain Injury：A Functional Magnetic Resonance Imaging Study
The overall goal of this study is to examine if acupuncture intervention can reduce the post-concussion symptom (PCS), and affective and cognitive complaints among mild traumatic brain injury (TBI).
- Conditions
- Acupuncture, Mild Traumatic Brain Injury, MRI
- Trial name
- NCT02868671
- Testing
- acupuncture
- Where
- China
- Volunteers
- 66 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Prematurity, Immune Defect
Different Doses of Vitamin D and T Regulatory Cells in Preterm Infants
This study evaluate the effect of two different doses of vitamin D on T-regulatory cells in preterm infants. Half of the subjects receives 400 IU vitamin D and the other half receives 800 IU vitamin D.
- Trial name
- NCT03793309
- Testing
- Vitamin D
- Volunteers
- 40 people
- Sponsor
- Cairo University
Anti-anxiety Agents, Moderate Sedation
Sublingual Versus Intranasal Administration of Dexmedetomidine for Sedation of Children Undergoing Dental Treatment
The aim of this study is to assess the efficacy of Dexmedetomidine drug either used sublingually or intranasally in managing healthy children during dental treatment
- Trial name
- NCT04237532
- Testing
- Intranasal Dexmedetomidine, Sublingual Dexmedetomidine
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Nourhan M.Aly
Healthy, Diabetes
Safety for 24 Weeks Intake of Korean Red Ginseng in Adults
Korean Red Ginseng appears to adverse events in adults taking 24 weeks Placebo and comparative assessment. And exploratory as Korean Red Ginseng blood sugar control, reduce body fat, URTI prevention, cardiovascular risk, renal…
- Conditions
- Healthy, Diabetes, Hypertension, Hyperlipidemia
- Trial name
- NCT02428998
- Testing
- Korean Red Ginseng
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Korea Ginseng Corporation
Periodontal Bone Loss, Periodontal Pocket
Treatment of Intraosseous Periodontal Defects With Hyaluronic Acid
The aim of the present investigation will be evaluate the healing of periodontal intraosseous defects following Minimally Invasive Non Surgical Debridement (MINSD) and application of a hyaluronic acid-based gel, compared to MINSD…
- Trial name
- NCT05188898
- Testing
- MINSD and Hyaluronic acid, MINSD
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Federico II University
Esophageal Squamous Cell Carcinoma (ESCC)
A Multicenter Trial of YSQTG vs. Simulated Agents With Neoadjuvant Chemoradiotherapy or Chemoimmunotherapy for EC
Esophageal cancer is a high - incidence cancer type in China, characterized by high incidence, high mortality, and low survival rates.
- Trial name
- NCT06863831
- Testing
- Yishen Qutong Granules, Yishen Qutong Simulant Granules
- Where
- China
- Volunteers
- 536 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Health Knowledge, Attitudes, Practice
Effect of a Nutritional Education Intervention in Female Athletes
This cluster randomized controlled trial aimed to evaluate the effect of a nutritional education intervention on sports nutrition knowledge, dietary intake, and body composition in adolescent female handball players.
- Trial name
- ATHENEA (NCT07460102)
- Testing
- Nutritional education program
- Where
- Spain
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Andreu Farran-Codina
Lateral Epicondylitis
Bundang Rehabilitative Impact Study of the Elbow Epicondylitis
This study is to assess the safety and effect of polydeoxyribonucleotide(PDRN) on the lateral epicondylitis with ultrasonography-guided injection of the PDRN or dextrose solution.
- Trial name
- BundangRISEe (NCT02492945)
- Testing
- 3ml-Rejuvinex, 3ml-15%-dextrose solution
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Bundang Hospital
Recurrent Congenital Talipes Equinovarus
SPLATT to Peroneus Brevis vs TATT to Lateral Cuneiform
Congenital talipes equinovarus, is a common congenital foot deformity involving hindfoot equinus and varus, along with mid-/forefoot adduction and cavus.
- Trial name
- Recurrent CTEV (NCT06300645)
- Testing
- SPLATT
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Assiut University
Candidiasis, Sepsis
Fluconazole Versus Micafungin for Candida Bloodstream Infection in Non-Neutropenic Patients
The purpose of this study is to verify the equivalence in clinical efficacy of fluconazole and micafungin for the treatment of Candida bloodstream infection in non-neutropenic patients.
- Trial name
- NCT00304772
- Testing
- Fluconazole, Micafungin
- Where
- Japan
- Sponsor
- Kyoto University
Pain
Do Emotions Affect Mechanical Pain Thresholds?
The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds.
- Trial name
- DEAMPT (NCT06074575)
- Testing
- Emotion induction
- Where
- Sweden
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Infertility
Comparing Two Different Embryo Transfer Catheters
Numerous published trials now document that the embryo transfer (ET) procedure has a huge impact on pregnancy and delivery rates after IVF (In Vitro Fertilization).
- Trial name
- CATH (NCT03161119)
- Testing
- Ultrasound guided embryotransfer with Cook K-Jets-551910-S, Ultrasound guided embryotransfer with Cook k-soft-5000 (or K-J-SP-681710 and K-J-SPPE-681710)
- Where
- Italy
- Volunteers
- 352 people
- Sponsor
- Istituto Clinico Humanitas
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