Clinical trials: Randomized-controlled Trial
Aortic Aneurysm
ELECT Trial - Embolization of the Lumbar Arteries Before EVAR
Prospective, Randomized, Single-center Study for the Treatment of Subjects with Abdominal Aortic Aneurysm: Embolization of the Lumbar Arteries Before EVAR: A Prospectively Randomized Trial Comparing Platinum-Fibered Microcoils…
- Trial name
- NCT03842930
- Testing
- Endovascular embolization
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Leipzig
Dental Caries
Effectiveness of Fissure Sealant and Topical Fluoride Application in Preventing Dental Caries
Nearly half of the 12-year-old children in China have dental caries (tooth decay) and most of the lesions are in the fissures of the first permanent molars.
- Trial name
- NCT01446107
- Testing
- placement of fissure sealant, fluoride varnish, silver fluoride
- Where
- China
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Any Non-traumatic Musculoskeletal Condition
Testing a Brief Reassurance Message Before a Musculoskeletal Clinic Visit
The goal of this clinical trial is to learn if a brief, reassuring pre-visit message affects patients' expectations and planned follow-up care in adults with common musculoskeletal conditions.
- Trial name
- NCT07330492
- Testing
- Nudge intervention
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Texas at Austin
Pain During and After Endovenous Laser Obliteration of Large Saphenous Vein Based on Lidocaine Tumescent Concentration
Efficacy of Variable Lidocaine Concentrations in Tumescent Anesthesia for Pain Control During and After Endovenous Laser Procedure; Non-inferiority Trial
Endovenous laser treatment is a minimally invasive procedure that has been shown to be a safe and effective treatment for varicose veins.
- Trial name
- NCT02192411
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Midwest Vein Center
Atopic Asthma
A Double Masked, Placebo Controlled, Single Center, Randomized Clinical Trial to Assess the Safety and Efficacy of Subjects With Mild Asthma Induced by the Bronchial Allergen Challenge (BAC)
A Double Masked, Placebo Controlled, Single Center, Randomized Clinical Trial to Assess the Safety and Efficacy of ADX-629 in Subjects with Mild Asthma Induced by the Bronchial Allergen Challenge (BAC)
- Trial name
- NCT04728711
- Testing
- ADX-629
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Aldeyra Therapeutics, Inc.
Parenting Stress, Positive Mental Health
Preliminary Efficacy of the AdoptMindful2Care@Web: A Web-Based Mindful Parenting Post-Adoption Intervention for Adoptive Parents
The development of post-adoption interventions aimed at promoting parental well-being and positive parenting is an urgent need. Mindful Parenting-based interventions appear to be particularly promising in this field, as they…
- Trial name
- NCT07534111
- Testing
- pAdoptMindful2Care@Web
- Where
- Portugal
- Volunteers
- 90 people
- Sponsor
- University of Coimbra
Chronic Constipation, Constipation
Perineal Self-Acupressure
The primary aim of this study is to test a non-medicinal technique for chronic constipation. The core of the technique is to have subjects repeatedly press on and massage their perineum before defecation to fragment and soften…
- Conditions
- Chronic Constipation, Constipation, Hemorrhoids
- Trial name
- NCT01867944
- Testing
- Perineal Self-Acupressure, Educational Control
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Los Angeles
Obesity, Abdominal
Efficacy of Electro-acupuncture for Abdominal Obesity: Study for a Randomized Controlled Trial
Electro-acupuncture provides stimulation to acupoints, and has been widely used to treat abdominal obesity in China despite of lack of high-level evidence for treatment efficacy.
- Trial name
- NCT04957134
- Testing
- Electro-acupuncture
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hubei Hospital of Traditional Chinese Medicine
Stroke, Rehabilitation
The Kinesio-taping for the Prevention of Painful Shoulder and for the Functional Recovery of Upper Limb After Stroke
This RCT aims to investigate the effectiveness of the early use of Kinesio-taping (KT) together with standard physiotherapy treatment, in the prevention of the shoulder pain of the hemiplegic upper limb following a cerebral…
- Trial name
- NCT05156164
- Testing
- Kinesio Tape Group, Control Group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Insomnia, Sleep-Disordered Breathing
CPAP vs ASV for Insomnia
The study will determine which of two different types of positive airway pressure (PAP therapy) modes are more effective in reducing sleep breathing events in chronic insomnia patients and in decreasing insomnia severity.
- Trial name
- P2P (NCT02365064)
- Testing
- AirCurve 10 ASV
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- ResMed
Ischemic Stroke
hsCRP in Japan Statin Treatment Against Recurrent Stroke (J-STARS hsCRP)
Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A(HMG-CoA) reductase can play a role in preventing recurrent vascular events from ischemic heart disease patients, whose mechanism consists in not only the reduction of serum…
- Trial name
- NCT00361699
- Testing
- Statin
- Where
- 2 sites in Japan
- Volunteers
- 1,095 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Prostate Cancer
Celecoxib Compared With No Treatment Before Surgery in Treating Patients With Localized Prostate Cancer
RATIONALE: Celecoxib may be an effective treatment for early stage prostate cancer. It is not yet known if celecoxib is more effective than no treatment before surgery for prostate cancer.
- Trial name
- NCT00022399
- Testing
- celecoxib
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Diabetic Neuropathies, Peripheral Nervous System Diseases
Effect of Physical Therapy in Improving the Health of Patients With Diabetic Peripheral Neuropathy
People with diabetes can have nerve damage in their extremities (peripheral neuropathy), and this can lead them to being less able to maintain their balance when they are standing, walking or performing complex movement tasks in…
- Trial name
- DPN-QoL (NCT02115932)
- Testing
- Strength & Balance Training
- Where
- Singapore
- Volunteers
- 143 people
- Sponsor
- National University Health System, Singapore
Depressive Disorder
Combining Antidepressants and Attention Bias Modification in Depression
Background: Major depressive disorder (MDD) is a highly prevalent psychiatric condition associated with significant disability, mortality and economic burden.
- Trial name
- DEPTREAT (NCT05503966)
- Testing
- Attentional Bias Modification
- Where
- Norway
- Volunteers
- 246 people
- Sponsor
- University of Oslo
Non-melanoma Skin Cancer
Topical Diclofenac and Topical DFMO Chemoprevention Trial in Subjects With a History of Skin Cancer
This is a single institution, randomized, placebo-controlled, double-blind phase IIB trial of 1) topical diclofenac and topical DFMO, or 2) placebo in participants with a history of non melanoma skin cancer/ keratinocytic cancers.
- Trial name
- NCT04091022
- Testing
- Solaraze and Vaniqa
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- University of Alabama at Birmingham
Waldenström Macroglobulinemia
The Comparison of RCD Versus BCD in Newly Diagnosed Waldenström Macroglobulinemia
The purpose of this study is to compare the efficacy of cyclophosphamide plus dexamethasone combined with rituximab or bortezomib regimens in newly diagnosed Waldenström macroglobulinemia patients.
- Trial name
- BDH-WM01 (NCT02844322)
- Testing
- Bortezomib, Rituximab
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Anxiety, Exercises Therapy
Progressive Relaxation Exercises on Anxiety Levels
The research will be conducted to determine the effect of progressive relaxation exercises on the anxiety level of patients who have had total knee replacement surgery.
- Conditions
- Anxiety, Exercises Therapy, Total Knee Replacement Surgery
- Trial name
- NCT06676202
- Testing
- Progressive Relaxation Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Knee Osteoarthritis
Tai Chi Mind-Body Therapy for Knee Osteoarthritis
The purpose of this study was to compare the safety and effectiveness of Tai Chi with an Attention Control intervention consisting of a stretching and wellness education program involving 40 patients with osteoarthritis (OA) of…
- Trial name
- NCT00362453
- Testing
- Tai Chi versus Attention Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Tufts Medical Center
Epistaxis Nosebleed
Tranexamic Acid Versus Blood Stopper Treatments in Epistaxis Management
In this randonmized controlled trial, aim to compare the effectiveness of local administration of tranexamic acid and blood stopper (Ankaferd®) on cessation of bleeding in epistaxis patients.
- Trial name
- NCT06490653
- Testing
- Blood Stopper (Ankaferd)
- Volunteers
- 186 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Osteo Arthritis Knee, Osteoarthritis
MRgFUS in the Treatment of Osteoarthritic Knee Pain
A double-blind placebo-controlled randomized clinical trial to evaluate the efficacy of magnetic resonance-guided focused ultrasound surgery (MRgFUS) in the treatment of pain caused by knee osteoarthritis (OA)
- Conditions
- Osteo Arthritis Knee, Osteoarthritis, Osteoarthritis, Knee
- Trial name
- NCT03453372
- Testing
- MRgFUS Treatment
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Istituto Ortopedico Rizzoli
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