Clinical trials: Randomized-controlled Trial
Kidney Diseases, Dialysis; Complications
PRevEnting FracturEs in REnal Disease - 1
PREFERRED-1 is a pilot study designed to determine the feasibility of a large randomized, pragmatic, open-label, comparative-effectiveness trial of denosumab for the prevention of fragility fractures in people receiving…
- Conditions
- Kidney Diseases, Dialysis; Complications, Fragility Fracture, Chronic Kidney Disease-Mineral and Bone Disorder
- Trial name
- PREFERRED-1 (NCT05096195)
- Testing
- Denosumab 60 mg/ml, Calcium and vitamin D prophylaxis, Monitoring of post-injection calcium and phosphate
- Where
- 6 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Western University, Canada
Uterine Cervical Dysplasia
Music and Colposcopy in Women With Cervical Dysplasia.
To assess the effect of music during colposcopy on women´s anxiety.
- Trial name
- NCT03005795
- Testing
- Headphones, No Headphones
- Where
- 2 sites in Germany
- Volunteers
- 205 people
- Sponsor
- Zydolab - Institute of Cytology and Immune Cytochemistry
Acupuncture, Knee Osteoarthritis
Acupuncture Treatment for Knee Osteoarthritis With Sensitive Acupoints and Tender Points
The investigators plan to investigate the effectiveness of acupuncture at highly sensitive points, compared with lowly/non-sensitive points or no acupuncture (waiting-list), in improving pain, joint function and quality of life…
- Conditions
- Acupuncture, Knee Osteoarthritis, Sensitive Acupoints, Tender Points
- Trial name
- NCT03299439
- Testing
- acupuncture
- Where
- 4 sites in China
- Volunteers
- 666 people
- Sponsor
- West China Hospital
Clinical High Risk for Psychosis
Randomized Controlled Trial of Aspirin vs Placebo in the Treatment of Pre-psychosis
The primary objective of this study is to determine whether aspirin is effective in alleviating symptoms of the clinical high risk (CHR) syndrome for psychosis.
- Trial name
- NCT02047539
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Yale University
Abdominal Aortic Aneurysm
Limb Remote Ischemic Preconditioning Reduces Heart and Lung Injury After Abdominal Aortic Aneurysm Repair
To investigate whether limb remote ischemic preconditioning (LRIP) has protective effects against intestinal and pulmonary injury in patients undergoing open infrarenal abdominal aortic aneurysm (AAA) repair.
- Trial name
- NCT01344239
- Testing
- Limb remote ischemic preconditioning(LRIP)
- Volunteers
- 62 people
- Sponsor
- Cai Li
Obesity
Effect of LAPS-Exendin on Body Weight in Obese Population
The purpose of this study is to determine the optimal dose and regimen of HM11260C, in combination with a hypocaloric diet, to reduce weight in obese subjects who are otherwise considered in stable health.
- Trial name
- NCT02075281
- Testing
- HM11260C
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Ketamine, Adjuvant
Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain
The aim of this study is to evaluate the role of ketamine as an adjuvant in external oblique intercostal plane block for post thoracotomy pain.
- Conditions
- Ketamine, Adjuvant, External Oblique Intercostal Plane Block, Thoracotomy
- Trial name
- NCT07138781
- Testing
- Ketamine, 29 ml bupivacaine 0.25% + 1 ml saline
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Neck Pain
The Effectiveness of Postural Stabilization Exercises in Patients With Chronic Neck Pain
This study aimed to evaluate the effect of postural stabilization exercises given in addition to cervical stabilization on craniovertebral angle, neck disability index, and quality of life in people with chronic neck pain.Sixty…
- Trial name
- NCT06578481
- Testing
- Exercises
- Where
- Cyprus
- Volunteers
- 60 people
- Sponsor
- European University of Lefke
Menopausal Women, Insomnia
The Effect of Valerian on Insomnia in Menopausal Women
Menopausal women often complain that it is difficult to fall asleep and easy to wake up at night and early in the morning and it is in the middle of night difficult to fall asleep again.
- Trial name
- NCT05185219
- Testing
- Valerian
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Motor Development, Physical Activity
Evaluation of the Move 2 Learn (M2L) Program for Young Children
Move 2 Learn (M2L) is a 10-week movement and pre-literacy program for preschool aged children and their parents designed to improve both movement and reading skills as well as support their overall cognitive, physical, and…
- Trial name
- NCT03999619
- Testing
- Move 2 Learn
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cervical Intraepithelial Neoplasia (CIN), Human Papillovirus
Local Hyperthermia for the Treatment of Cervical Persistent High-risk Infection
Human papillomavirus(HPV) infect epithelial cells and have the capacity to stimulate cell abnormal hyperplasia, especially by those high-risk HPV types.
- Trial name
- NCT07059819
- Testing
- Local hyperthermia device
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Hospital of China Medical University
Cancer of Head and Neck
RCT of Effects of Mindfulness-based Stress Reduction in Head and Neck Cancer
Head and neck cancer is a group of biologically similar cancers which cause deleterious impact, such as the complication of facial disfigurement which may increase the psychological vulnerability of patients due to the society's…
- Trial name
- NCT04800419
- Testing
- Mindfulness-based Stress Reduction (MBSR)
- Where
- Malaysia
- Volunteers
- 110 people
- Sponsor
- Universiti Sains Malaysia
Granulocyte Colony-Stimulating Factor (G-CSF) Mobilization
CHRONO-MOBILIZE: Chronotherapy of G-CSF for CD34+ Mobilization in Healthy Donors
Healthy donors are commonly mobilized with granulocyte colony-stimulating factor (G-CSF) to collect peripheral blood stem cells for allogeneic hematopoietic stem cell transplantation (allo-HSCT).
- Trial name
- CHRONO-MOBILIZ (NCT07423728)
- Testing
- G-CSF (Granulocyte colony-stimulating factor)
- Where
- 3 sites in China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Necrotic Teeth With Chronic Apical Periodontitis
Regenerative Endodontics in Mature Necrotic Teeth
The goal of this clinical trial is to learn if nanochitosan can achieve regeneration in mature necrotic teeth. It will also provide data about the healing potential \& postoperative pain after using different irrigation…
- Trial name
- NCT07584928
- Testing
- Intervention 1: 1% nanochitosan, Intervention 2: 1% nanochitosan & 17% EDTA
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Suez Canal University
Breast Neoplasm Female
Football Fitness After Breast Cancer
Late effects of breast cancer treatment are widely reported including deteriorating fitness, fatigue, loss of muscle and bone mass, and increased body fat percentage.
- Trial name
- FFABC (NCT03284567)
- Testing
- Football fitness
- Where
- Denmark
- Volunteers
- 69 people
- Sponsor
- University of Copenhagen
Lumbar Herniated Intervertebral Disc
Biportal Endoscopic Discectomy Versus Microdiscectomy: RCT, Non-inferiority Trial
This study is to compare the clinical outcome between the biportal endoscopic discectomy and microdiscectomy in herniated intervertebral disc of lumbar spine
- Trial name
- BESS (NCT03924700)
- Testing
- Biportal endoscopy, Microdiscectomy
- Where
- 2 sites in South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Bowel Preparation Solution
App-Based Education and Low-Residue Diet for Colonoscopy Preparation
This prospective, randomized, evaluator-blind, parallel-group trial is designed to objectively compare the effectiveness of Advanced Bowel Preparation versus Traditional Bowel Preparation in patients undergoing colonoscopy.
- Trial name
- NCT07395492
- Testing
- Tian Tian Yi Chi go APP (developed by UIC Corp), Prepackaged Low-Residue Diet
- Volunteers
- 420 people
- Sponsor
- Chang Gung Memorial Hospital
Drain Output After Breast Reduction Surgery, Breast Reductions
Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery
This study aims to evaluate whether tranexamic acid (TXA), a medication that helps reduce bleeding, can decrease fluid drainage after breast reduction surgery.
- Trial name
- NCT07131592
- Testing
- IV TXA, Topical TXA, Topical saline
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
Low-output External Gastrointestinal Fistula
Glue Application in the Treatment of Low-Output Fistulas
Adjuvant use of fibrin glue (FG) in the fistula tract has been shown to promote closure of low-output enterocutaneous fistulas (ECFs).
- Trial name
- FG-treatment (NCT01828892)
- Testing
- Endoscopy exploration and glue application, Endoscopy exploration, Antibiotics (ceftazidime, cefotaxime, or meropenem, with or without vancomycin)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jinling Hospital, China
Urinary Retention
Post Hysterectomy Benefits of Retained Cystoscopy Fluid
The purpose of this research study is to compare outcomes for women in two study arms that include retaining the cystoscopy distending fluid after minimally invasive hysterectomy verses completely emptying the cystoscopy…
- Trial name
- NCT03646136
- Testing
- Retained fluid, Emptied fluid
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Arizona
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