Clinical trials: Randomized-controlled Trial
Fibromyalgia
High-intensity Laser Therapy Improves Pain, Health Status and Quality of Life in Women With Fibromyalgia
This study will be conducted to investigate High-intensity laser therapy improves pain, health status and quality of life in women with fibromyalgia
- Trial name
- NCT05904990
- Testing
- traditional exercise therapy only, HILT alongside traditional exercise therapy
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- October 6 University
Over Active Bladder, Urinary Incontinence (UI)
Electroacupuncture as a Treatment for Refractory Overactive Bladder
This study is a single-site feasibility randomised controlled trial evaluating the feasibility and acceptability of electroacupuncture (EA), and percutaneous tibial nerve stimulation (PTNS), in women with refractory overactive…
- Conditions
- Over Active Bladder, Urinary Incontinence (UI), Nocturia
- Trial name
- EAOAB (NCT07124390)
- Testing
- Name: Electroacupuncture (EA) Type: Device-based acupuncture therapy, Neuromodulation therapy
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Anxiety, Digital Eye Strain
Reducing Eye Strain and Anxiety Using a Digital Intervention During Online Learning Class Recess Among Children at Home: A Randomized Controlled Trial
The primary aim of the current study is to conduct a cluster-randomized control trial to evaluate the effectiveness of a novel digital intervention in reducing anxiety and digital eye strain compared to usual care among Chinese…
- Trial name
- RESILIENT (NCT04309097)
- Testing
- Digital intervention, Information-only intervention
- Where
- China
- Volunteers
- 954 people
- Sponsor
- Sun Yat-sen University
Diabetes Mellitus, Type 2, Nicotine Dependence, Cigarettes
Effect of Glucagon-like Peptide-1 (GLP-1) Receptor Agonist Stimulation on Smoking Consumption in Type 2 Diabetes Patients
Diabetes has become an increasingly serious global health issue. In 2024, approximately 537 million adults were living with diabetes, and this number is projected to rise to 783 million by 2045, representing a 46% increase.
- Trial name
- NCT06924697
- Testing
- Application of GLP-1RAs drugs, DPP-4i group
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Shanghai East Hospital
Blood Cholesterol
Efficacy and Safety of Unripe Bokbunja Extract on Improvement of Blood Cholesterol
This study was conducted to investigate the effects of daily supplementation of unripe Bokbunja extract on improvement of blood cholesterol.
- Trial name
- NCT03649620
- Testing
- unripe Bokbunja Extract
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Tuberculosis
Electronic Pillbox-enabled SAT Versus DOT for TB Medication Adherence and Treatment Outcomes
To address the multifaceted challenges associated with tuberculosis (TB) in-person directly observed therapy (DOT), the World Health Organization recently recommended countries maximize the use of digital adherence technologies.
- Trial name
- SELFTB (NCT04216420)
- Testing
- MERM-observed self-administered therapy
- Where
- Ethiopia
- Volunteers
- 114 people
- Sponsor
- Addis Ababa University
Medical Education, Simulation
Does Teaching Before or After Simulation Improve Learning?
The goal of the randomized educational intervention study is to test whether simulation preceding didactic teaching leads to improved knowledge and performance retention compared to a didactic lecture proceeding simulation for…
- Trial name
- NCT06092320
- Testing
- Simulation on Pediatric Status Epilepticus, Didactic Lecture on Pediatric Status Epilepticus
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Sleep Disturbance, Fatigue
The Effects Of Kiwifruit Consumption On Sleep Quality, Fatigue And BMI Of Saudi Adults
Hypothesis: Kiwifruit contains antioxidants and serotonin which may be beneficial in the treatment of sleep disruption. Aim: to assess the effects of daily intake of kiwifruit on sleep quality, fatigue, and BMI among Saudi adults…
- Conditions
- Sleep Disturbance, Fatigue, Body Weight
- Trial name
- NCT05953324
- Testing
- Kiwifruit
- Where
- Saudi Arabia
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Chronic Mechanical Neck Pain
Bruegger's Relief Exercise in Chronic Mechanical Neck Pain
The aim of this randomized controlled trial is to determine the effect of Bruegger's Relief Exercise combined with conventional physical therapy on pain intensity, functional disability, cervical range of motion, and…
- Trial name
- NCT07791680
- Testing
- Bruegger's Relief Exercise + Conventional Physical Therapy, Conventional Treatment
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Spastic Diplegia, Cerebral Palsy
Effect of Core Stability Training on Segmental Trunk Control and Quality of Life in Children with Cerebral Palsy
Spastic diplegia is a common shape of cerebral palsy that significantly affects trunk control and quality of life in children. Core stability training (CST) has been utilized as a potential intervention to improve the trunk…
- Trial name
- NCT06822296
- Testing
- Physical Therapy, Designed rehabilitation program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cesarean Section Complications
Effect of Three Weight-adjusted Vasopressors for Elective Cesarean Delivery
This study compared the effects of prophylactic infusion of metaraminol, phenylephrine and norepinephrine adjusted according to body weight on fetal acid-base balance and maternal hemodynamics.
- Trial name
- NCT04991662
- Testing
- metaraminol, Phenylephrine, Norepinephrine
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Xuzhou Medical University
Acute Kidney Injury
Ultra-Low Contrast Angiography in AKI
The aim of this study is to evaluate the safety of ultra-low contrast coronary angiography in patients with pre-existing acute kidney injury.
- Trial name
- NCT05906758
- Testing
- Angiography
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Tulane University
Hyperparathyroidism, Kidney Disease
Safety and Efficacy Study of Paricalcitol Versus Calcitriol in the Treatment of Secondary Hyperparathyroidism
The purpose of this study is to determine whether oral paricalcitol is safer and more efficacious compared to oral calcitriol in the treatment of hyperparathyroidism in chronic kidney disease patients undergoing dialysis.
- Trial name
- NCT00800358
- Testing
- Paricalitol, Calcitriol
- Where
- 11 sites in Malaysia
- Volunteers
- 69 people
- Sponsor
- Penang Hospital, Malaysia
Tourette Syndrome in Adolescence
Is Medicinal Cannabis an Effective Treatment for Tourette Syndrome in Adolescents? a Pilot Study
This is a single site, pilot double-blind, randomized, placebo-controlled, cross-over study of 10 participants comparing medicinal cannabis (THC:CBD 10:15 oil) with placebo in reducing tics in adolescents aged 12 - 18 years with…
- Trial name
- NCT05184478
- Testing
- Medicinal cannabis (MC): THC 10mg/mL : CBD 15mg/mL, manufactured by Cann Group Ltd.
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Murdoch Childrens Research Institute
Alzheimer's Disease
Online Caregiver Psychoeducation and Support for Alzheimer's
This study is piloting an internet-based intervention to provide support for caregivers of VA patients with Alzheimer's disease or related memory difficulties (ADRD).
- Trial name
- NCT00416078
- Testing
- caregiver website support, caregiver brief supportive phone calls
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- US Department of Veterans Affairs
Acute Kidney Injury
Tunneled Dialysis Catheters Versus Non-tunneled Dialysis Catheters as First-line for Renal Replacement Therapy in the ICU
The investigators propose a randomized controlled trial to examine whether tunneled dialysis catheters should be first-line for acute kidney injury requiring renal replacement therapy (AKI-RRT) in the critical care setting…
- Trial name
- BACKDOOR (NCT03496935)
- Testing
- Tunneled versus non-tunneled dialysis catheter insertion
- Volunteers
- 102 people
- Sponsor
- Brigham and Women's Hospital
Type 2 Diabetes
Degludec Glargine U300 Hospital Study
Limited data exist about the use of insulin degludec and insulin glargine U300 in the hospitalized patients. A previous study compared the safety and efficacy of insulin degludec versus insulin glargine U100 for the management of…
- Trial name
- NCT05036876
- Testing
- Degludec, Glargine U300
- Where
- India
- Volunteers
- 220 people
- Sponsor
- Medanta, The Medicity, India
Knee Osteoarthritis, Blood Loss
Extended Postoperative Oral Tranexamic Acid in Knee Replacement
A comparison of outcomes between use of oral tranexamic acid as compared to oral placebo in the first days after total knee replacement will be made to determine impact on clinical indications and patient reported outcomes.
- Conditions
- Knee Osteoarthritis, Blood Loss, Pain, Postoperative
- Trial name
- NCT05099276
- Testing
- Tranexamic Acid Pill
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Campbell Clinic
Healthy
A Study of V330 in Healthy Younger (18 to 49 Years Inclusive) and Healthy Older (60 to 79 Years Inclusive) Participants (V330-001)
The goal of this study is to learn whether a new vaccine, V330, is safe and learn how well the body's immune system responds by making antibodies after receiving V330.
- Trial name
- NCT06630117
- Testing
- V330
- Where
- 4 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Cancer Related Fatigue
Trial of Exercise to Reduce Cancer Related Fatigue in Breast Cancer
Like other cancer treatments, radiation therapy can make people feel fatigued, or tired. The investigators think that moderate exercise, done 15 minutes at a time, can reduce the fatigue.
- Trial name
- NCT02846389
- Testing
- Moderate Exercise
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Hackensack Meridian Health
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