Clinical trials: Rapid Diagnosis
Epilepsy, Refractory
Using Micro-filaments to Detect "fast Ripples" and Improve the Identification of the Epileptogenic Zone
record fast ripples with novel intracranial electrodes with micro-tetrodes to improve the identification of epileptogenic zone (EZ) and investigate the neuronal circuits underlying brain dynamics associated with epilepsy
- Trial name
- NeuroSeizure (NCT05254730)
- Testing
- macro-micro tetrodes for intracranial recording
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Adrien Peyrache
Fever, Malaria
Role and Effectiveness of Rapid Diagnostic Tests in Home-based Management of Malaria
Most malaria deaths occur within 48 hours of onset of symptoms, and in rural areas with poor access to health facilities, home management of malaria (HMM) can improve the timeliness of treatment and reduce malaria mortality by up…
- Trial name
- ACTUGA2 (NCT01048801)
- Testing
- Rapid diagnostic test, presumptive malaria treatment
- Where
- Uganda
- Volunteers
- 2,000 people
- Sponsor
- DBL -Institute for Health Research and Development
Bipolar Disorder
Interval Training in Bipolar Disorder
Our main objective will be to evaluate the chronic effects (12 weeks) of high-intensity interval training compared to moderate intensity (same total work) on reducing the symptoms of bipolar disorder, cortical changes, as well as…
- Trial name
- HIIT (NCT02498730)
- Testing
- Interval Training, Continuous Training, Control
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
HIV, Substance Abuse
Transitions: Linkages From Jail To Community
TRANSITIONS, a novel jail-release program for People Living with HIV/AIDS (PLWHA), will use evidence-based interventions and adapt them to create a comprehensive transitional program in Waterbury and New Haven County…
- Conditions
- HIV, Substance Abuse, HIV Infections
- Trial name
- NCT00841711
- Testing
- Intensive Case Management
- Where
- 2 sites in United States
- Volunteers
- 127 people
- Sponsor
- Yale University
Colon Cancer, Diverticulum, Colon
ERAS Lazio Network Clinical Registry
Enhanced recovery after surgery (ERAS) protocols are programs aiming to implement patients recovery following surgical procedures developed about 25 years ago.
- Trial name
- ENeRgy (NCT03353311)
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- PERSIANI ROBERTO
Major Depressive Disorder
Biomarkers of Social Sensitivity in Major Depression
Major depression disorder (MDD) is a frequent and disabling mental disorder with great risk of recurrence and chronicity. Interpersonal factors are among the strongest predictors of the course and duration of an episode of…
- Trial name
- SENSO (NCT02214511)
- Testing
- emotional facial stimuli, Cyberball game
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Peripheral Nerve Injuries
Evaluating the Safety and Efficacy of Polyethylene Glycol (PEG) Mediated Fusion (PEG Fusion)
The overall objective of this study is to determine the safety of PEG fusion when used with primary repair or reconstruction in patients with an acute upper extremity peripheral nerve injury.
- Trial name
- NCT04789044
- Testing
- NTX-001
- Where
- 7 sites in United States
- Volunteers
- 40 people
- Sponsor
- Major Extremity Trauma Research Consortium
Bone Metastases
Rapid Radiation Therapy for Painful Osseous Metastatic Disease
The purpose of this research study is to evaluate the safety and effectiveness of an experimental workflow that may result in a faster way to plan and deliver radiation for the treatment of pain caused by metastatic bone tumors…
- Trial name
- NCT01391234
- Testing
- STAT RT planning and delivery workflow
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Virginia
Chronic Rhinitis, Chronic Pharyngitis
Efficacy and Safety of High-Concentration 35 kDa Hyaluronan Gel for Chronic Nasopharyngitis
This is a prospective, single-arm, open-label, pilot clinical study to evaluate the efficacy and safety of nasopharyngeal administration of 13.6% high-concentration 35 kDa hyaluronan (HA35) care gel in subjects with chronic…
- Conditions
- Chronic Rhinitis, Chronic Pharyngitis, Nasopharyngitis, Posterior Pharyngeal Inflammation
- Trial name
- HA35 (NCT07568548)
- Testing
- 13.6% High-Concentration 35 kDa Hyaluronan (HA35) Nasopharyngeal Care Gel
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nakhia Impex LLC
Pharyngitis
Evaluation of Accuracy of Rapid Tests for Group A Beta Hemolytic Streptococci in Out-patients With Sore Throat
The purpose of this study is to evaluate accuracy of rapid tests for group A beta hemolytic streptococci in patients who presented with sore throat at out patient department in Siriraj Hospital.
- Trial name
- NCT02623985
- Testing
- Sofia, QuickVue, Throat swab culture
- Volunteers
- 360 people
- Sponsor
- Mahidol University
Breast Cancer Invasive
Fast and Accurate Breast Cancer Diagnosis Using Nanopore Sequencing in Tanzania (Fast-ABCD Sequencing)
This pilot study will test the feasibility of using nanopore sequencing for breast cancer diagnosis in Tanzania. It aims to show that nanopore sequencing is non-inferior to the current standard of care, with the potential for…
- Trial name
- NCT06633276
- Where
- Tanzania
- Volunteers
- 100 people
- Sponsor
- University of Bonn
COVID-19, SARS-CoV-2
COVIDISC: Rapid Diagnostic Tests on Nasopharyngeal Swabs for the Detection of COVID-19
The Covid-19 pandemic requires a reliable diagnosis of patients in order to take care of them in the best conditions and in the appropriate services.
- Trial name
- COVIDISC (NCT04703140)
- Testing
- Rapid Diagnostic Test vs PCR
- Where
- France
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- CMC Ambroise Paré
Acute Coronary Syndrome
Rapid Assessment of Cardiac Markers for the Evaluation of Acute Coronary Syndrome (RACE-ACS)
This clinical trial is being conducted to 1) evaluate the possible usefulness of a panel of cardiac markers in assessing emergency department patients with possible acute coronary syndrome, 2) evaluate the usefulness of BNP in…
- Trial name
- NCT00206817
- Testing
- Triage CardioProfilER (Troponin I, Myoglobin, CK-MB, BNP)
- Where
- 6 sites in United States
- Sponsor
- Abbott RDx Cardiometabolic
Schizophrenia
Proposal To Develop A Rapid And Cost-Effective Diagnostic Test For Schizophrenia
Schizophrenia is a severe psychotic illness of unknown cause that affects 1% of the population worldwide. Currently, there is no diagnostic test for schizophrenia.
- Trial name
- NCT03781115
- Testing
- Ziprasidone, Olanzapine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Primary Aldosteronism Due to Aldosterone Producing Adenoma
Rapid Cortisol Assay in Adrenal Vein Sampling
Background: Adrenal vein sampling (AVS) is the gold standard test for the subtyping of primary aldosteronism (PA). This procedure is hampered by unsuccessful bilateral cannulation of adrenal veins, which can occur in up to two…
- Trial name
- I-PADUA (NCT03449797)
- Testing
- AVS performed with no intraprocedural rapid cortisol assay, AVS performed plus intraprocedural rapid cortisol assay
- Volunteers
- 200 people
- Sponsor
- University Hospital Padova
Sepsis, Bloodstream Infection
Rapid Molecular Diagnosis of Sepsis in the Intensive Care Unit
Rapid diagnosis of sepsis is crucial for treatment and survival. Currently, blood culture takes 48 hours-5 days to complete. After starting antimicrobial treatment blood culture results are not reliable.
- Trial name
- RADOS (NCT06624618)
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Maastricht University Medical Center
Chest Pain, Myocardial Ischemia
Rapid Acute Coronary Syndrome Exclusion Using High-sensitivity I Troponin
As part of the planned implementation of a new clinical pathway using hs-cTnI, the investigators will measure patient outcomes and clinical processes in a real-world scenario throughout an integrated health system across 9…
- Trial name
- RACE-IT (NCT04488913)
- Testing
- RACE-IT Pathway, Standard of Care
- Where
- United States
- Volunteers
- 32,609 people
- Sponsor
- Henry Ford Health System
Emergency
Rapid Sequence Intubation at the Emergency Department
All patients undergoing emergent endotracheal intubation (RSI) at the Emergency Department will be screened for inclusion in this clinical study.
- Trial name
- NCT02297113
- Testing
- Macintosh blade, C-MAC videolaryngoscope
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University of Zurich
Type 1 Diabetes Mellitus
TAK-329 Glucose Clamp Study
The purpose of this study is to compare the safety, tolerability, pharmacokinetic and pharmacodynamic properties of single doses of TAK-329 with a single dose of a subcutaneously-injected rapid-acting insulin analog in…
- Trial name
- NCT01311076
- Testing
- TAK-329, Insulin
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Takeda
Irritable Bowel Syndrome (IBS)
The Diagnostic Predictability of Food Allergy Testing
Irritable bowel syndrome (IBS) sufferers often find that specific foods can exacerbate their symptoms; identifying which foods involves a long and arduous process.
- Trial name
- FAST (NCT01791621)
- Testing
- Elimination/Challenge Diet
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- The Canadian College of Naturopathic Medicine
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