Clinical trials: Rapid Diagnosis
New Coronavirus
Development of a Simple, Fast and Portable Recombinase Aided Amplification Assay for 2019-nCoV
In late December 2019, several local health facilities reported clusters of patients with pneumonia of unknown cause that were epidemiologically linked to a seafood and wet animal wholesale market in Wuhan, Hubei Province, China.
- Trial name
- NCT04245631
- Testing
- Recombinase aided amplification (RAA) assay
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Ditan Hospital
Gingivitis, Maxillary Transversal Deficiency
St. John's Wort Oil Versus Chlorhexidine Mouthwash for Gingival Problems After Rapid Maxillary Expansion
The goal of this clinical trial was to learn whether St. John's wort (Hypericum perforatum) oil helps gum healing in children and adolescents aged 11 to 16 years after treatment with a rapid maxillary expansion appliance.
- Trial name
- SJW-CHX-RME (NCT07882771)
- Testing
- St. John's Wort Oil, Chlorhexidine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Abdominal Diseases
Rapid Abdominal Diagnosis With AI & Radiology
This study aims to develop an AI-assisted diagnostic system for abdominal contrast-enhanced CT images using data from multiple inpatient centers.
- Trial name
- RADAR (NCT07040358)
- Where
- China
- Volunteers
- 2,000,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Multiple Sclerosis
A run-in Study on the Safety and Tolerability of a Fasting Mimicking Diet in Relapsing Remitting Multiple Sclerosis
This study is an open-label, single-arm, run-in study in patients with RRMS treated with first line therapies (interferon-beta, glatiramer acetate, teriflunomide and dimethyl fumarate), assessing the feasibility and tolerability…
- Trial name
- FAST-MS (NCT06039007)
- Testing
- 7-day Fasting-Mimicking Diet (7-DAY FMD)
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Ospedale Policlinico San Martino
Plasmodium Falciparum, Pregnancy Malaria
Clinical Performance of the HRP2 HS-RDT for Malaria Diagnosis in Pregnant Women
This is a cross-sectional and multicentre clinical trial to study the performance of the Histidine Rich Protein 2 (HRP2) highly sensitive rapid diagnostic test (HS-RDT) for the detection of malaria during pregnancy in low…
- Conditions
- Plasmodium Falciparum, Pregnancy Malaria, Diagnoses Disease
- Trial name
- HSRDT MiP (NCT03172221)
- Testing
- HS-RDT
- Where
- 2 sites in Colombia
- Volunteers
- 880 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Low Cardiac Output
Hemodynamic Survey Cardiac Surgical Scenarios
The purpose of this study is to find out the Lidco Rapid ( monitoring tool gives cardiac output) is as equivalent in determining the hemodynamic assessment in cardiac surgical scenarios as the most often used pulmonary artery…
- Trial name
- NCT02529033
- Testing
- LIDCO Rapid, Pulmonary artery catheter
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Movement Disorder, Cognitive Decline
Next Generation Sequencing Diagnostics - On the Road to Rapid Diagnostics for Rare Diseases
In the study, NextGen SE are on-hand a cohort comprising each 50 pediatric and 50 adult patients, and in which there are an unclear movement disorder or an unclear cognitive disorder, examines the following questions : Primary…
- Trial name
- NextGen-SE (NCT02588638)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Tuebingen
SARS-CoV Infection, Nurse's Role
Systematic Offer of Nurse-Driven Screening for COVID-19 in Emergency Departments in the Paris Metropolitan Area, DEPIST-COVID
European countries faced another wave of the SARS-CoV2 pandemic, which has led to a second lockdown in France in November 2020 in order to avoid overwhelming health services.
- Trial name
- DEPIST-COVID (NCT04756609)
- Testing
- Systematic offer of nurse-driven SARS-CoV-2 screening combined with usual practice, Usual emergency department practice with physician-directed diagnostic testing
- Where
- France
- Volunteers
- 138,352 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer
FAST MRI Study in Breast Cancer Survivors
Breast Magnetic Resonance Imaging (MRI) has been shown to be the most accurate test for detecting breast cancer however, MRI is not always reliable because it can indicate the presence of cancer when in reality, there is none…
- Trial name
- NCT02244593
- Testing
- FAST MRI and mammography screening
- Where
- Canada
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Length of Stay, Complications
Study Comparing Conventional and Fast Track Multi-Discipline Treatment Interventions for Colorectal Cancer
A new notion"Fast Track Multi-Discipline Treatment" for colorectal cancer is thought with several benefits such as shorter hospitalization stay and less costs.
- Conditions
- Length of Stay, Complications, Adverse Drug Event, Quality of Life
- Trial name
- NCT01080547
- Testing
- Laparoscopic Surgery for Colorectal Cancer, XELOX Chemotherapy, mFolfox6 chemotherapy
- Where
- 2 sites in China
- Volunteers
- 374 people
- Sponsor
- Zhejiang University
Acute Ischemic Stroke
Rapid Local Ischemic Postconditioning on Stroke After Thrombectomy
The main goal of this study is to find out if a new, quick "brain rescue" procedure can help people recover better from a severe stroke caused by a large vessel occlusion.
- Trial name
- RAPIDIMPROVE (NCT07598799)
- Testing
- High-dose RL-IPostC, Low-dose RL-IPostC
- Where
- China
- Volunteers
- 448 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Relaxation Training for People With Chronic Obstructive Pulmonary Disease (COPD)
People with Chronic Obstructive Pulmonary Disease (COPD) suffer from dyspnoea, which may be exacerbated by psychological outcomes including anxiety and depression.
- Trial name
- NCT02698904
- Testing
- Guided Relaxation Technique, Documentary Movie
- Where
- Italy
- Volunteers
- 39 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Urinary Tract Infection (Diagnosis)
Rapid Point-of-care Bacteriuria and Microbial Susceptibility for Women With Suspected Uncomplicated Urinary Tract Infections: Diagnostic Accuracy in General Practice.
In this study, adult women presenting at their general practitioner with a likely bladder infection (with symptoms like a burning sensation when urinating, pain in the lower abdomen, and frequent or urgent need to urinate) will…
- Trial name
- NCT06625268
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Wuerzburg University Hospital
Thyroid Neoplasms, Hyperparathyroidism
Dual-Channel Near-Infrared Autofluorescence Imaging and AI Analysis to Locate Parathyroid Glands (PTFinder)
This study tests PTFinder, a dual-camera system that makes parathyroid glands glow on screen by capturing their natural near-infrared autofluorescence.
- Conditions
- Thyroid Neoplasms, Hyperparathyroidism, Parathyroid Gland
- Trial name
- PTFinder (NCT07010380)
- Testing
- PTFinder Dual-Channel NIR Autofluorescence Imaging System, Offline Machine-Learning Algorithm (PTFinder-AI Beta)
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Bo Wang,MD
Ischemic Stroke, Hemorrhagic Stroke
A Randomized Trial Comparing 2 Methods for Rapid Induction of Cooling in Stroke Patients, Cold Infusions vs. RhinoChill (iCOOL 1)
Mild hypothermia improves outcome in patients with global cerebral ischemia after cardiac arrest. Hypothermia seems promising also in other acute hypoxic-ischemic or in brain swelling associated cerebrovascular disease.
- Trial name
- iCOOL 1 (NCT01573117)
- Testing
- RhinoChill, Cold crystalloid infusions, 0.9%NaCl or Ringer's solution
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Heidelberg
Hydronephrosis, Kidney Swelling
MRI Hydronephrosis Study
The purpose of this study is to compare a rapid noncontrast MRI protocol not requiring sedation to ultrasound in the assessment of hydronephrosis.
- Trial name
- NCT01588340
- Testing
- MRI (Magnetic resonance imaging), Ultrasound exam
- Where
- United States
- Sponsor
- University of Michigan
Control Patients, Class III Malocclusion
Effect of Face Mask Therapy on Blood Oxygen Levels
Skeletal Class III malocclusions are characterized by maxillary retrusion, mandibular protrusion, or a combination of both. In growing individuals presenting with maxillary deficiency, the face mask appliance is widely recognized…
- Trial name
- NCT06939179
- Testing
- Class III Malocclusion
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Biruni University
Primary Aldosteronism Due to Aldosterone Producing Adenoma
Rapid Cortisol Assay in Adrenal Vein Sampling
Background: Adrenal vein sampling (AVS) is the gold standard test for the subtyping of primary aldosteronism (PA). This procedure is hampered by unsuccessful bilateral cannulation of adrenal veins, which can occur in up to two…
- Trial name
- I-PADUA (NCT03449797)
- Testing
- AVS performed with no intraprocedural rapid cortisol assay, AVS performed plus intraprocedural rapid cortisol assay
- Volunteers
- 200 people
- Sponsor
- University Hospital Padova
Chronic Obstructive Pulmonary Disease (COPD), Mechanical Ventilator Weaning
D-RSBI Versus RSBI for Predicting Weaning Success in COPD Patients
This prospective observational cohort study aims to compare the predictive accuracy of diaphragmatic rapid shallow breathing index (D-RSBI) versus traditional rapid shallow breathing index (RSBI) for predicting weaning success…
- Trial name
- NCT07590362
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Vulvar Cancer, Ovarian Cancer
Study of a Rapid Triadic Communication Intention Elicitation Intervention to Improve Supportive Oncology Care Delivery
The purpose of this study is to help test an idea designed to foster more supportive talk between providers (doctors or nurse practitioners), patients, and caregivers during an outpatient oncology appointment.
- Conditions
- Vulvar Cancer, Ovarian Cancer, Uterine Cancer, Vaginal Cancer
- Trial name
- PRECursOr (NCT05995860)
- Testing
- Intervention group triads
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Indiana University
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