Clinical trials: Rapid Diagnosis
Primary Open Angle Glaucoma
STudy to Assess Rapid Disease Progression by Clinical and Genetic Factors In Glaucoma patientS That Are High Risk
The purpose of this study is to perform exploratory analyses to evaluate rates of functional and structural change in glaucoma, to identify predictors of rapid progression in patients with glaucoma and to identify possible…
- Trial name
- STARFISH (NCT01442896)
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Intubation; Difficult or Failed
Comparison of Ultrasound Techniques for Assessment of Endotracheal Tube Placement
This study is a single-center, randomized clinical trial conducted in an emergency department on intubated patients with rapid sequence intubation.
- Trial name
- NCT06656546
- Testing
- Tracheal Ultrasound, Lung Ultrasound, Diaphragm Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Palatal Expansion Technique, Malocclusion
Comparison Between Two Rates of Activation of Miniscrew-Supported Upper Jaw Expander in Adolescents
Miniscrew-supported maxillary expanders provide advantages over conventional tooth-supported expanders. However, there is no consensus in the literature regarding their activation protocol.
- Conditions
- Palatal Expansion Technique, Malocclusion, Posterior Crossbite, Maxillary Hypoplasia
- Trial name
- NCT04225637
- Testing
- Miniscrew-Supported Maxillary Expander- Slow activation, Miniscrew-Supported Maxillary Expander- Rapid activation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Nocturnal Enuresis
Nocturnal Enuresis and Rapid Maxillary Expansion
Nocturnal enuresis (NE) is the involuntary loss of urine that occurs only at night in children aged 5 years or more. NE is a common problem, affecting about 10% of school children.
- Trial name
- NERME (NCT02178826)
- Testing
- Rapid Maxillary Expansion
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Uppsala University Hospital
Post Traumatic Stress Disorder
Clonazepam and Paroxetine for Rapid Treatment of Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder (PTSD) is an anxiety disorder that follows exposure to an extremely traumatic stressors. PTSD is associated with serious symptoms.
- Trial name
- NCT00025740
- Testing
- clonazepam and paroxetine
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- National Institute of Mental Health (NIMH)
Heart Rate Fast, Heart Rate Low
Accuracy of the Apple Watch Series 4 for Detection of Heart Rhythm: A Pilot Study
The objective of this study is to assess the accuracy of the Apple Watch 4 Series watch in generating an ECG that is suitable for determination of heart rhythm compared to rhythms monitored via telemetry.
- Trial name
- NCT03798613
- Testing
- Apple Watch 4 Series Device, Continuous Telemetry Monitor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
Covid19, Asymptomatic Shedding Viral
COVID-19 Rapid Testing for Self-Administration Among an Asymptomatic Sample
Point-of-care testing can provide an additional layer of protection to reduce transmission of COVID-19 safely and effectively in the population, and if such tests can be self-administered, barriers to access may be reduced.
- Trial name
- NCT04896710
- Testing
- SD Biosensor
- Where
- Canada
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Type 1 Diabetes
Testing a Conversion Factor for a More Rapidly Acting Insulin in an Automated Insulin Delivery System Among Adolescents With T1D
A randomized controlled trial of Control-IQ, assessing glycemic control (time-in-range 70-180 mg/dL) for Lyumjev insulin (in which the insulin settings have been determined using an experimental conversion factor) as compared to…
- Trial name
- Lpad Lyumjev (NCT06948760)
- Testing
- Control-IQ insulin pump with Lyumjev insulin, Control-IQ insulin pump with Humalog or Novolog
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Mark D. DeBoer, MD, MSc., MCR
Traumatic Brain Injury
Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury
This study will look to validate predictive algorithms developed in a previous study where we collected relevant data from trauma registry and after using advanced signal-processing and machine-learning, determined prediction…
- Trial name
- RAPID-TBI (NCT05084352)
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- University of Maryland, Baltimore
Drug Use, Pre-exposure Prophylaxis (PrEP)
Pre-exposure Prophylaxis (PrEP) Rapid Access
The goal of phase 1 is to determine the feasibility and acceptability of an intervention ('Rapid PrEP Access') providing people who use drugs (PWUD) one-time access to HIV self-testing at the Victory Program.
- Conditions
- Drug Use, Pre-exposure Prophylaxis (PrEP), Opioid Use Disorder
- Trial name
- NCT05528562
- Testing
- PrEP Rapid Access, HIV self-testing, Dried blood spot testing
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston Medical Center
Atrial Fibrillation
Low Dose of Diltiazem for Rate Control of Atrial Fibrillation
This study is to show the efficacy and safety of low dose diltiazem for the treatment of atrial fibrillation with rapid ventricular response in emergency room.
- Trial name
- NCT00834925
- Testing
- low dose diltiazem
- Where
- South Korea
- Volunteers
- 380 people
- Sponsor
- Seoul National University Hospital
COVID-19, SARS-CoV-2
PCR and Rapid Diagnostic Test on Saliva and Nasopharyngeal Swabs for the Detection of SARS-CoV-2 (COVID-19)
Recent literature shows that the sensitivity of the PCR tests for the detection of SARS-CoV-2 using saliva samples is close to that using nasopharyngeal swabs.
- Trial name
- RaDiCo (NCT04613310)
- Testing
- Rapid Diagnostic Test vs PCR
- Where
- Switzerland
- Volunteers
- 949 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Diabetes Mellitus, Experimental
Cardiometabolic Effects of Rapid Glucose Excursion
The effects of rapid glucose excursions, induced by intravenous bolus application of glucose in healthy probands, on cardiometabolic and inflammatory parameters will be investigated
- Trial name
- ERGE (NCT04488848)
- Testing
- bolus glucose, continuous clucose
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Barmherzige Brüder Linz
Psychotic Disorders
Fast Titration Of Quetiapine Versus Currently Approved Titration
The purpose of this study is to evaluate the safety and tolerability of a more rapid dose titration in acute schizophrenic patients compared to the conventional titration.
- Trial name
- NCT00254813
- Testing
- Quetiapine
- Where
- 7 sites in Norway
- Volunteers
- 150 people
- Sponsor
- AstraZeneca
Major Depressive Disorder, Alcohol Use Disorder
Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder
The investigators will compare 3 treatment groups (ketamine plus naltrexone vs. ketamine alone vs. placebo) for treating major depressive disorder (MDD) and alcohol use disorder (AUD) in an 8-week randomized, double-blind…
- Trial name
- NCT02461927
- Testing
- Ketamine + Naltrexone
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- VA Office of Research and Development
Schizophrenia
An Open-label Study Evaluating the Maintenance of Clinical Effect in Adult Schizophrenia Patients Switched From Risperidone Tablets to an Equivalent Dose of a Rapidly-dissolving Tablet Formulation of Risperdone
The purpose of this study is to evaluate the maintenance of clinical effect of a rapidly-dissolving tablet form of risperidone (an antipsychotic medication) in adult schizophrenia patients switched from their previous equivalent…
- Trial name
- NCT00246272
- Testing
- risperidone
- Volunteers
- 82 people
- Sponsor
- Janssen-Ortho Inc., Canada
Aortic Valve Stenosis
The Pacing vs No Pacing Study - PNP Study
Pilot interventional study, without drug, randomized 1: 1, open-label comparison of efficacy and safety between the technique of percutaneous balloon aortic valvuloplasty without rapid ventricular pacing vs valvuloplasty during…
- Trial name
- PNP (NCT02498639)
- Testing
- percutaneous balloon aortic valvuloplasty
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Immune Thrombocytopenic Purpura
A Randomized Study of IVIG vs. IVIG With High Dose Methylprednisolone in Childhood ITP.
Childhood immune thrombocytopenia purpura (ITP) is a disorder characterized by the production of antibodies against platelets, resulting in enhanced destruction of platelets.
- Trial name
- NCT00376077
- Testing
- Methylprednisolone and IVIG
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- The Hospital for Sick Children
Sepsis, Septic Shock
Evaluation of Droplet Digital PCR Rapid Detection Method and Precise Diagnosis and Treatment for Suspected Sepsis
Sepsis is a significant public health concern worldwide, with high morbidity and mortality. With regard to a targeted antimicrobial treatment strategy, the earliest possible pathogen detection is of crucial importance.
- Trial name
- NCT05190861
- Testing
- droplet digital PCR method, blood culture
- Where
- 9 sites in China
- Volunteers
- 1,032 people
- Sponsor
- Huashan Hospital
Obesity
Fast Food Photo Study
The investigators aim to discover if people of different demographic levels are more or less attentive to changes in calorie information vs. changes in price information on a restaurant menu.
- Trial name
- NCT02267954
- Testing
- Menu edited
- Where
- 2 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
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