Clinical trials: Reading Disorder
Congenital Deafness
Neuroanatomy of Reading in Congenital Deafness.
The aim of the research is to investigate phonological processing in deafness and to examine its influence on the neuroanatomy of reading.The basic hypothesis is that insofar as the ability to read is closely related to the…
- Trial name
- NCT00400413
- Testing
- fMRI
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Developmental Dyslexia
Immediate Effects of Active Prisms on Reading Automaticity and Motor Control in Young Adults With Developmental Dyslexia
Developmental dyslexia is associated with persistent difficulties in reading automaticity. AUTO-DYS investigates whether a single, brief intervention using active prisms changes the complexity of nonlinear movement dynamics and…
- Trial name
- AUTO-DYS (NCT07868367)
- Testing
- Individually Selected Active Prisms.
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Lille University
Dyslexia, Learning Disorders
Comprehensive Program to Improve Reading and Writing Skills in At-Risk and Dyslexic Children
This project is evaluating programs to improve reading and writing skills in children who have or are at risk for having reading disabilities.
- Trial name
- NCT00061412
- Testing
- Comprehensive program to improve reading and writing skills
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cerebellar Ataxias
The Benefits of Long-read High-throughput Genomic Sequencing for the Causal Diagnosis of Cerebellar Ataxias
Cerebellar ataxias are a group of rare neurological disorders that are clinically and genetically heterogeneous, with several hundred genes and diseases known to date.
- Trial name
- ALICA (NCT06467175)
- Testing
- blood sampling for high molecular weight DNA extraction
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Myopia
Side Effects of Atropine (SEA) Study
This study will perform several objective and subjective measurements of the eye and vision before and after a week of using 0.01% concentration atropine drops.
- Trial name
- SEA (NCT03593044)
- Testing
- 0.01% concentration atropine drops
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Jeffrey J. Walline, OD PhD
Myopia
Myopia Prevention With Reading Glasses
The last decades have seen a significant increase in myopia in children and young adults. Possible cause: increased near-work (school, computer, smartphone).
- Trial name
- SMART2 (NCT05030103)
- Testing
- Reading glasses, +2.0 diopters
- Where
- Liechtenstein
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Reis Augenklinik AG
Developmental Delay
Bright by Three (BB3) Effectiveness Study
The Investigators propose to conduct a pragmatic randomized controlled trial of 350 one to four year old children and their caregivers to study the effectiveness of 1) the Bright By Three (BB3) intervention for promoting…
- Trial name
- NCT02717390
- Testing
- Bright By Three (BB3), Texts for Child Safety (TCS)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Vision Disorders, Reading Disabilities
Efficacy of Coloured Overlays and Lenses for Reading Difficulty
This is a randomised controlled trial with the aim of testing the efficacy of coloured overlays and coloured lenses for the relief of visual stress and reading difficulties in children and young adults.
- Trial name
- NCT02680223
- Testing
- Precision tinted lenses, Non-beneficial tinted lenses
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- City, University of London
Developmental Disability, Developmental Dyslexia
Postural Control, Grip Strength and Body Posture in Children With Intellectual Disability and Dyslexia
This study investigates physical changes in children with Dyslexia and Intellectual Disability. Participants divided into three groups and Body Posture, Postural Control and Hand Grip Strengths was evaluated.
- Conditions
- Developmental Disability, Developmental Dyslexia, Intellectual Disability
- Trial name
- NCT04250701
- Testing
- Body Posture Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ahmet Emir
Reading Disability, Dyslexia
Eye Movements and Reading Disabilities
The mechanism of the eye movement anomalies seen in dyslexic patients is not well defined. Some optometrists use observational eye movement tests as screening devices for dyslexia and advocate eye movement therapy as a treatment…
- Trial name
- EOMRD (NCT01860027)
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Scripps Health
Glaucoma, Suspect, Diabetic Retinopathy
Eye Health Intervention Study in Upper Manhattan
Individuals living in Upper Manhattan have limited access to eye care, high vision impairment rates, and poor ocular health outcomes.
- Conditions
- Glaucoma, Suspect, Diabetic Retinopathy, Cataract, Refractive Errors
- Trial name
- EYES-UM (NCT06112431)
- Testing
- Intervention, Usual Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Dry Eye Syndromes, Sjogren's Syndrome
Effects of Sustained Reading on the Ocular Surface
This research is being done to to see if changes in visual reading function correlate with changes in optical and retinal image quality.
- Trial name
- NCT02031172
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Child Development
Effects of Application of a Motor Programme on Neurological Maduration in Children
The persistence of primitive reflexes in school-age children can affect neuromotor maturation. Some studies link the persistence of primitive reflexes with specific learning difficulties, low academic performance…
- Trial name
- Move&Learn (NCT06030310)
- Testing
- The developmental Exercise Programme of INPP
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fundació Universitària del Bages
Developmental Dyslexia, Reading Problem
Personalization of Visual Characters and Text-to-Speech (TTS) to Support Learning in Students With Reading Difficulties
Previous research has shown the importance of font type, size and spacing to facilitate text reading in dyslexia. A special automatized procedure was designed to select the most favorable parameters for both text visualization…
- Trial name
- NCT06947512
- Testing
- Seleggo Test
- Where
- 3 sites in Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Reading Disorder
Gene x Environment Interplay in Developmental Dyslexia Treatment: A Round-trip Translation Between Humans and Animal
Developmental dyslexia affects 7% of school-age children (Male:Female ratio of 1.5:1) and incurs disadvantages in education and occupation.
- Trial name
- Gedys (NCT06186882)
- Testing
- Action Video-Game
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Developmental Dyslexia
Restoring Neural Oscillatory Communication in Developmental Dyslexia
Developmental dyslexia (DD) is a multifactorial disorder that hampers the education of about 10% of individuals across cultures and is associated to both phonological and visual deficits.
- Trial name
- NCT05583136
- Testing
- Parietal tACS combined with visuo-attentional training
- Where
- Italy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- IRCCS Ospedale San Raffaele
Dyslexia, Dysphasia
Developmental Language Difficulties: Behavioural and Electrophysiological Studies
This study will help to better characterize oral and written language disorders and determine if these disorders are continuous or not.
- Trial name
- LANGAGE (NCT02872870)
- Testing
- auditory lexical decision task, electroencephalogram
- Where
- 3 sites in Belgium, France
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Developmental Dyslexia, Developmental Coordination Disorder
Functional MRI Study in Children With a Developmental Coordination Disorder (DCD) and/or Developmental Dyslexia (DD)
All the studies underlined the high frequency of co-morbid associations in specific learning disorders. Understanding the reasons for these associations could enable us to determine the cerebral bases that underlie each disorder.
- Trial name
- FMRI-DCD-DD (NCT02393729)
- Testing
- Neuropsychological assessment, MRI Study
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Reading Disorders
Impact of Motor Tasks and Lidocaine on Reading Unfamiliar Words in Adults With and Without Dyslexia
Recent claims report that reading ability is partially dependent on speech production. While the evidence for this claim is compelling, it is not known to what extent, the speech production system contributes to successful…
- Trial name
- NCT05854082
- Testing
- Lidocaine 2% Polyampoule
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Alberta