Clinical trials: Recent Stroke
Stroke, Ischemic Attack, Transient
Home Blood Pressure Monitoring Trial
Design: Community based randomised trial with follow up after 12 months Participants: 360 patients admitted with stroke or TIA within the past 9 months will be recruited from the wards or outpatients and randomly allocated into…
- Trial name
- NCT00514800
- Testing
- Intervention - a validated home BP monitor and support from the specialist nurse, Control - usual care (BP monitoring by their practice)
- Where
- 3 sites in United Kingdom
- Volunteers
- 360 people
- Sponsor
- St George's, University of London
Ischemic Stroke, Hypercholesteremia
Early Statin-Ezetimibe Combination vs. Statin Monotherapy in Stroke With Atherosclerosis
This study will be conducted at six medical institutions in Taiwan, recruiting patients who visit neurology outpatient clinics or are hospitalized within 30 days after an ischemic stroke.
- Trial name
- NCT07307989
- Testing
- statin + ezetimibe, Statin monotherapy (rosuvastatin or atorvastatin)
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Acute
Rate of Atrial Fibrillation Through 12 Months in Patients With Recent Ischemic Stroke of Presumed Known Origin
The purpose of the Stroke AF study is to compare the incidence of atrial fibrillation (AF) through 12 months between continuous cardiac rhythm monitoring with the Reveal LINQ™ Insertable Cardiac Monitor (ICM) (continuous…
- Trial name
- NCT02700945
- Testing
- Reveal LINQ™ Insertable Cardiac Monitor
- Where
- 35 sites in United States
- Volunteers
- 496 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Stroke
Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent Embolic Stroke of Undetermined Source (ESUS)
This is a study in patients who recently had a brain attack (stroke) and in whom no clear cause of the stroke could be identified.
- Trial name
- NAVIGATE ESUS (NCT02313909)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Acetylsalicylic acid (Aspirin, BAY1019036)
- Where
- 454 sites in United States, Argentina and 29 more
- Volunteers
- 7,213 people
- Sponsor
- Bayer
Ischemic Stroke, Atrial Fibrillation
Single-stage Pulmonary Vein Isolation Combined With Percutaneous Left Atrial Appendage Occluder Implantation in Patients With Recent Onset Ischemic Stroke and Atrial Fibrillation
The project is a multicenter, open-label, randomized medical experiment, which was designed to evaluate the efficacy and safety of single-stage pulmonary vein isolation (PVI) and implantation of left atrial appendage occluder…
- Trial name
- PILOS-AF (NCT06212674)
- Testing
- PVI + LAAO, single stage, LAAO, NOAC
- Where
- 2 sites in Poland
- Volunteers
- 240 people
- Sponsor
- Medical University of Silesia
Stroke, Stroke (in Patients With Atrial Fibrillation)
Thrombolysis in Factor Xa-inhibitors Trial
This study looks at whether stroke patients who take FXa inhibitors (a type of blood thinner) can safely receive clot-busting treatment (IVT).
- Conditions
- Stroke, Stroke (in Patients With Atrial Fibrillation), Ischemic Stroke, Acute Ischemic Stroke
- Trial name
- SIFT (NCT06878066)
- Testing
- thrombolysis therapy
- Where
- 21 sites in Denmark, Norway and 1 more
- Volunteers
- 300 people
- Sponsor
- Guri Hagberg
Stroke
Adaptive Optics (AO) Analysis of Retinal Arteries in Patients With Recent Stroke (STROKAO)
The eye has long been recognized as a window to pathological processes occurring in the brain. By imaging the vascular system of the retina scientific understanding and clinical practice have been improved for a wide range of…
- Trial name
- STROKAO (NCT04712747)
- Testing
- Ophthalmological examinations, Blood pressure measurement at rest
- Where
- France
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Stroke/Brain Attack, Upper Extremity Paresis
Tendon Vibrations Effect on Upper Limb Motor Recovery After Recent Stroke
Stroke is the leading cause of severe acquired disabilities in adults. It can affect sensory and motor functions which are closely entangled. Among them, upper limb function is often strongly impaired.
- Trial name
- VIBRAMOT (NCT04504214)
- Testing
- Upper limb repeated multi-site tendon vibrations
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Borelli UMR 9010
Atrial Fibrillation
7-day Holter Monitoring in Adult Patients With Recent IS or TIA, to Measure the Prevalence of Paroxysmal Atrial Fibrillation Including Episodes Less Than 30 Seconds: Transversal Study
The main outcome of this study will be to compare the prevalence of PA AF episodes longer than 30 seconds versus the prevalence of PA AF episodes including episodes shorter than 30 seconds, in adult patients who survived IS or…
- Trial name
- MY-ATRIA (NCT04963647)
- Testing
- Adult subjects diagnosed with IS or TIA
- Where
- Italy
- Volunteers
- 660 people
- Sponsor
- Azienda Usl di Bologna
Ischemic Stroke, Hypertension
Home Blood Pressure Study for Recent Stroke Survivors With High Blood Pressure *On Hold Due to Global Pandemic*
The purpose of this pilot study is to assess the feasibility of implementing a home blood pressure self-management program in a population of recent stroke survivors in the Washington, D.C. area.
- Trial name
- HBPS (NCT04226157)
- Testing
- Home Blood Pressure Monitoring Device (Qardio Arm), Primary Care Provider Blood Pressure Management
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- MedStar Georgetown University Hospital
Stroke, Ischemic
Study on Rosuvastatin+Ezetimibe and Rosuvastatin for LDL-C Goal in Patients With Recent Ischemic Stroke
A randomized clinical trial for the comparison of the efficacy and safety of moderate-intensity rosuvastatin plus ezetimibe versus high-intensity rosuvastatin for target LDL-C goal achievement in patients with recent ischemic…
- Trial name
- NCT03993236
- Testing
- Experimental: Rosuvastatin/Ezetimibe 10, Active Comparator: Rosuvastatin 20mg
- Where
- 12 sites in South Korea
- Volunteers
- 584 people
- Sponsor
- Keun-Sik Hong
Acute Ischemic Stroke
Tenecteplase for Intravenous Stroke Thrombolysis in Recent DOAC Users
An investigator-initiated, multicenter, randomized, placebo-controlled, double-blind trial to determine the efficacy and safety of intravenous tenecteplase thrombolysis in acute ischemic stroke (AIS) patients with recent direct…
- Trial name
- PEARL-DOAC (NCT07092709)
- Testing
- Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg)
- Where
- China
- Volunteers
- 912 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Recent Stroke, Pulmonary Embolism
Pulmonary Embolism and Stroke in Patient With Patent Foramen Ovale
The cause of ischemic stroke remains frequently unknown. In patients with patent foramen ovale (PFO), the link between PFO and Stroke is unclear.
- Conditions
- Recent Stroke, Pulmonary Embolism, Patent Foramen Ovale
- Trial name
- EPIC-FOP (NCT01216423)
- Where
- 4 sites in France
- Volunteers
- 374 people
- Sponsor
- University Hospital, Brest
Stroke, Ischaemic Stroke
Atrial Fibrillation Detected by ELR and Holter Recording, a Comparison in Patients With Ischemic Stroke or TIA
Purpose 1. To validate 2 -day loop recording ( R.Test Evolution 4 ) to 2 -day Holter recording (gold standard) for the detection of atrial fibrillation of ≥ 30 seconds duration in a consecutive population of patients with stroke…
- Conditions
- Stroke, Ischaemic Stroke, Atrial Fibrillation, Supra Ventricular Extra Systoles
- Trial name
- NCT02155907
- Where
- Denmark
- Volunteers
- 1,507 people
- Sponsor
- University of Aarhus
Acute Coronary Syndromes (ACS), Recent Myocardial Infarction
The Pharmacokinetics and Pharmacodynamics Study of Evategrel CG-0255 Besylate）and Plavix® in Healthy Participants
CG-0255 is a novel investigational prodrug of the active metabolite of Plavix®， but with different active metabolite conversion routes.
- Conditions
- Acute Coronary Syndromes (ACS), Recent Myocardial Infarction, Recent Stroke, Peripheral Arterial Disease
- Trial name
- NCT07619885
- Testing
- CG-0255 Besylate for Injection, CG-0255 Besylate Capsule, Clopidogrel
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Shanghai CureGene Pharmaceutical Co., Ltd.
Stroke
Triple Antiplatelets for Reducing Dependency After Ischaemic Stroke
The risk of recurrence is greatest immediately after stroke or Transient Ischaemic Attack (TIA). Existing prevention strategies (antithrombotic, lipid/blood pressure lowering, endarterectomy) reduce, not abolish, further events.
- Trial name
- TARDIS (NCT01661322)
- Testing
- Aspirin, Dipyradimole, Clopidogrel
- Where
- United Kingdom
- Volunteers
- 3,096 people
- Sponsor
- University of Nottingham
Ischemic or Hemorrhagic Stroke
Impact of Art Therapy on Brain Connectivity in Recent Post-Stroke Aphasia
A stroke located in the left parieto-temporal junction is associated, in aphasic right-handed patients, with a poor prognosis for language recovery.
- Trial name
- ART-CONNECT (NCT03820843)
- Testing
- Art therapy and standard orthophonic rehabilitation
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pain
Central Post-Stroke Pain - a Prospective Study
Part 1: The purpose of the first part of the study is to investigate the prevalence of pain at stroke onset and 3 and 6 months after stroke in a consecutive cohort of stroke patients admitted to a stroke unit.
- Trial name
- NCT00957645
- Volunteers
- 275 people
- Sponsor
- Danish Pain Research Center
Ischemic Cerebrovascular Accident
Clopidogrel for Acute Ischaemia of Recent Onset
Evaluate the role of loading Clopidogrel in acute ischemic stroke in improving neurological outcome of stroke in cases patients will be non-eligible for, or declined, treatment with or intravenous thrombolysis with rTPA, rTPA is…
- Trial name
- CAIRO (NCT02776540)
- Testing
- Clopidogrel, Aspirin
- Where
- Egypt
- Volunteers
- 188 people
- Sponsor
- Ain Shams University
Acute Ischemic Stroke
Efficacy and Safety of Tenecteplase Among acutE Ischemic Stroke Patients With Recent Ingestion of Direct Oral Anticoagulant
The study will randomize patients with acute ischemic stroke and Direct Oral AntiCoagulants (DOAC) ingestion within 48 hours from enrollment (but otherwise eligible for thrombolysis) to administration of intravenous tenecteplase…
- Trial name
- ESTER-DOAC (NCT07621796)
- Testing
- Intravenous tenecteplase (TNK)
- Where
- United States
- Volunteers
- 660 people
- Sponsor
- Hackensack Meridian Health