Clinical trials: Reconstruction
Medial Patellofemoral Dislocation, Medial Patellofemoral Ligament Reconstruction
Medial Patellofemoral Ligament Reconstruction in Children - a 2-8 Years Follow-up Study
The purpose of this project is to investigate the treatment outcome after MPFL reconstruction in children as a treatment for chronic patellar instability, where the superficial part of the quadriceps tendon is fixed to the femur…
- Trial name
- MPFL (NCT06257836)
- Testing
- MPFL-reconstruction
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Oral Cavity Carcinoma, Flap
Flap Sparing in Postoperative Radiotherapy of Oral Cavity Cancers
Patients with oral cavity cancer treated by reconstructive surgery with a flap. Patients will be treated in the study for : Experimental arm: Post-operative radiotherapy with flap sparing Control arm: Standard post-operative…
- Conditions
- Oral Cavity Carcinoma, Flap, Radiotherapy, Adjuvant, Reconstruction Surgery
- Trial name
- OPTIFLAP (NCT06798922)
- Testing
- Standard post-operative radiotherapy without flap sparing (current practice), Post-operative radiotherapy with flap sparing
- Where
- 30 sites in France
- Volunteers
- 348 people
- Sponsor
- Centre Francois Baclesse
Oral Squamous Cell Carcinoma (OSCC), Postoperative Pain
Effectiveness of Hydrogen Water Intervention on Acute Oral Inflammation, Oral Microbiota, and Pain Following Free Flap Reconstruction in Patients With Oral Cancer
This randomized, double-blind, parallel-group controlled trial evaluates the effectiveness of hydrogen water oral care on acute oral inflammation, oral microbiota, and pain in patients with oral cancer who have undergone free…
- Conditions
- Oral Squamous Cell Carcinoma (OSCC), Postoperative Pain, Postoperative Oral Mucositis, Free Flap Reconstruction
- Trial name
- NCT07306546
- Testing
- Hydrogen Water Oral Care, Water Oral Care
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Full-Thickness Skin Graft Reconstruction of Nasal and Auricular Surgical Defects
Full-Thickness Skin Graft Sizing and Scar Quality
This study will compare three different full-thickness skin graft sizes (90%, 100%, and 110% of the surgical defect size) in patients undergoing reconstruction of nasal or ear surgical defects.
- Trial name
- NCT07896317
- Testing
- Full-Thickness Skin Graft Sizing
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Radical Prostatectomy, Robotic Radical Prostatectomy
Continence Post Retzius-Sparing Versus Standard Robot-Assisted Radical Prostatectomy
To compare the short term (three month) continence rates using versius robotic system between the Retzius-sparing and the standard RARP within three month from removal of catheter.
- Conditions
- Radical Prostatectomy, Robotic Radical Prostatectomy, Retzius-sparing Robot-assisted Radical Prostatectomy With "Sandwich" Technique of Total Urethral Reconstruction
- Trial name
- Continence (NCT07899268)
- Testing
- Procedure: Retzius-Sparing Robot-Assisted Radical Prostatectomy (RS-RARP), Standard Robot-Assisted Radical Prostatectomy (S-RARP)
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Armed Forces College of Medicine, Cairo, Egypt
Bone Reconstruction by Free Fibula Flap
Functional Impact of Reconstructive Surgery by Harvesting a Vascularized Free Fibula Flap Postoperatively.
The fibula is a leg bone that can be used in complex bone reconstruction by reconstructive surgery. This innovative surgical procedure is increasingly used in complex facial (mandibular) reconstructions following cancer and…
- Trial name
- FIBULAM (NCT05641597)
- Testing
- Actimetric measurement, Evaluation of plantar flexion, dorsal flexion and ankle eversion forces, Assessment of static and dynamic balance and quality of life
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Surgical Wound Infection, Neck Infection
Antibiotic Tissue Penetration and Tissue Response in Head and Neck Infection and Reconstructive Surgery
The goal of this study is to measure how well commonly used antibiotics reach the tissue in the head and neck region in adults with a postoperative neck infection or undergoing reconstructive nasal surgery with an inferior…
- Conditions
- Surgical Wound Infection, Neck Infection, Nasal Reconstruction
- Trial name
- ANTIBIOTIKA (NCT07896239)
- Testing
- Cefuroxime, Dicloxacillin, Cloxacillin
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Tejs Ehlers Klug
Breast Reconstruction, Free Flap Reconstruction
ESP Blocks in Breast Free Flaps
This study is a prospective randomized controlled trial to assess the efficacy of erector spinae plane (ESP) blocks in patients undergoing autologous free flap breast reconstruction.
- Trial name
- NCT07891039
- Testing
- Bupivacaine with Epinephrine and Dexamethasone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Carilion Clinic
Breast Reconstruction, Breast Cancer Patients
Autologous Nerve Graft Breast Reconstruction Neurotization
The goal of this observational study is to learn about the improvement of quality of life in accordance with breast neurotization in breast cancer patients. The patient-reported outcome was assessed by questionnaire.
- Conditions
- Breast Reconstruction, Breast Cancer Patients, Nipple-sparing Mastectomy
- Trial name
- NCT06629012
- Testing
- Breast reconstruction with neurotization, Breast reconstruction without neurotization
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- Chang Gung Memorial Hospital
Breast Reconstruction After Mastectomy
Thermal Preconditioning in Mastectomy Patients With Immediate Breast Reduction
The purpose of this research study is to understand patient experiences and the feasibility of using a breast heat preconditioning device (Plexaa BLOOM43), designed to improve postoperative outcomes when used prior to mastectomy…
- Trial name
- NCT07516483
- Testing
- 1 Cycle Thermal Preconditioning, 3 Cycles Thermal Preconditioning, No Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wake Forest University Health Sciences
Hamstring Muscle Strain, Adult Acquired Flatfoot Deformity
Correlation Between Soft Tissue Displacement and Functional Performance in Orthopedic Patients
The goal of this clinical trial is to investigate the correlations between dynamic soft tissue displacement, mechanical properties, and functional recovery across three studies: biceps femoris long head (BFlh) muscle injury…
- Conditions
- Hamstring Muscle Strain, Adult Acquired Flatfoot Deformity, Ulnar Collateral Ligament Sprain After Reconstruction
- Trial name
- NCT07870408
- Testing
- Nordic Hamstring Exercise Training, Custom Foot Orthoses and Exercise Therapy, Forearm Blood Flow Restriction Training
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Breast Reconstruction
Pulsed Lavage in Implant-Based Breast Reconstruction
To determine if there is any benefit to using pulsed lavage to wash out the mastectomy pocket during breast reconstruction. Primary outcomes will include post-op complications including surgical site infection (SSI), hematoma…
- Trial name
- NCT05585710
- Testing
- Pulsed Lavage Washout, Implant-based breast reconstruction, Bilateral or unilateral mastectomy
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Alabama at Birmingham
Anterior Cruciate Ligament Reconstruction Rehabilitation, Dry Needling
Dry Needling and Quad Strength After Anterior Cruciate Ligament Reconstruction
Dry needling is a skilled intervention provided by trained physical therapists to treat pain, myofascial dysfunction, and a variety of other diagnosis.
- Conditions
- Anterior Cruciate Ligament Reconstruction Rehabilitation, Dry Needling, Strength
- Trial name
- ACLR (NCT07657195)
- Testing
- Dry Needling
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Children's Mercy Hospital Kansas City
Orbital Volume, Orbital Floor Reconstruction
Comparison Study Between Custom Made and Ready Made Titanium Mesh in Orbital Floor Reconstruction
compare between Custom made titanium mesh and ready-made titanium mesh in reconstruction of orbital floor.
- Trial name
- NCT07879729
- Testing
- reconstruction of orbital floor with custom made mesh, reconstruction of orbital floor with ready made mesh
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Injuries
Supporting Athletes' Return to Sports After ACL Reconstruction: A Study of a Psychological Readiness Program
The goal of this clinical trial is to learn whether an online mental and emotional support program called ACL Unbroken can help people recovering from ACL reconstruction surgery feel more confident and ready to return to sports…
- Conditions
- Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Tear
- Trial name
- UnbrokenACL (NCT07851298)
- Testing
- Unbroken Comeback
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Inova Health Care Services
Anterior Cruciate Ligament Reconstruction (ACLR), Anterior Cruciate Ligament Reconstruction Rehabilitation
The Effect of Isokinetic Vs Plyometric Training in Post-ACLR Surgery
The primary goal of this RCT is to evaluate the effects of isokinetic training compared to plyometric training in patients aged 18-40 years who have undergone ACLR surgery.
- Conditions
- Anterior Cruciate Ligament Reconstruction (ACLR), Anterior Cruciate Ligament Reconstruction Rehabilitation, Anterior Cruciate Ligament/Surgery, Anterior Cruciate Ligament (ACL) Reconstruction Surgery
- Trial name
- NCT07862868
- Testing
- Isokinetic Training, Plyometrics Training
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Anterior Cruciate Ligament Reconstruction (ACLR), Anterior Cruciate Ligament Reconstruction Rehabilitation
The Effect of Plyometric Training in Post-ACLR Surgery
The primary goal of this RCT is to evaluate the effect of adding plyometric training on standard program intervention in patients aged 18-40 years who have undergone ACLR surgery.
- Conditions
- Anterior Cruciate Ligament Reconstruction (ACLR), Anterior Cruciate Ligament Reconstruction Rehabilitation, Anterior Cruciate Ligament/Surgery, Anterior Cruciate Ligament (ACL) Reconstruction Surgery
- Trial name
- NCT07862881
- Testing
- Standard program, Plyometrics Training
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
ACL Reconstruction
Effects of Blood Flow Restriction Training and Instrument-Assisted Soft Tissue Mobilization for Pain, Strength, Range of Motion, and Kinesiophobia Among ACL Reconstruction Patients.
This randomized clinical trial aims to compare the effects of Blood Flow Restriction Training (BFR) and Instrument-Assisted Soft Tissue Mobilization (IASTM) on pain, quadriceps muscle strength, knee range of motion (ROM), and…
- Trial name
- NCT07662850
- Testing
- Blood Flow Restriction Training, Instrument-Assisted Soft Tissue Mobilization (IASTM)
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Anterior Cruciate Ligament Reconstruction, Medial Patellofemoral Ligament Reconstruction
Anterior Femoral and Adductor Canal Nerve Blocks in Peds Knees
The goal of this pilot clinical trial is to compare anterior femoral cutaneous nerve block (AFCN) to adductor canal block ACB) for pediatric patients undergoing either anterior cruciate ligament (ACL) or medial patellofemoral…
- Trial name
- NCT06590402
- Testing
- Bupivacaine, Dexamethasone in Adductor Canal Block, Bupivacaine, Dexamethasone in Anterior Femoral Cutaneous Nerve Block
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Lymphatic Reconstruction
Prospective Assessments Following Immediate Lymphatic Reconstruction
Immediate lymphatic reconstruction (ILR) is a novel surgical approach performed at the time of initial lymph node dissection with the goal of preventing lymphedema.(Chang et al.
- Trial name
- NCT07227467
- Testing
- patients who are candidates for immediate lymphatic reconstruction
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago