Clinical trials: Recovery of Function
Functional Recovery, Upper Extremity Vascularized Composite Allotransplantation
Upper Extremity Vascularized Composite Allotransplantation: A Study Evaluating Safety, Functional Outcomes, and Patient-Reported Psychosocial Outcomes
The primary objective of this study is to evaluate the 5-year (60-month) allograft survival rate of upper extremity vascularized composite allotransplantation performed under the standardized CONSORT clinical protocol.
- Trial name
- NCT07810790
- Testing
- Upper Extremity Vascularized Composite Allotransplantation (VCA)
- Where
- 9 sites in United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Radial Nerve Palsy, Functional Outcome
Fractures of the Humeral Shaft With Primary Radial Nerve Palsy
This study addresses the question if patients with fractures of the humeral shaft and primary radial nerve palsy gain nerve recovery.
- Trial name
- NCT03948542
- Testing
- Outcome
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Health, Subjective
Does Application Time Influence the Effect of Massage on Pain and Performance?
Introduction: The massage technique is widely used for post-exercise recovery, however, there is still a gap regarding the ideal dosage in relation to the duration of its application.
- Trial name
- NCT06537245
- Testing
- Massage
- Where
- Brazil
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Norte do Parana
Laparoscopic Abdominal Surgery
Study on the Effects of Multimodal Analgesia Regimens on Postoperative Analgesia and Gastrointestinal Function Recovery After Laparoscopic Abdominal Surgery
This clinical trial aims to investigate the impact of multimodal analgesia regimens on postoperative pain management and gastrointestinal function recovery following laparoscopic abdominal surgery.
- Trial name
- NCT06772545
- Testing
- Epidural Analgesia, Paravertebral Block, Transversus Abdominis Plane Block
- Volunteers
- 120 people
- Sponsor
- Xiaguang Duan
Traumatic Brain Injury
Vitamin B12 vs B3 for Nerve Regeneration and Functional Recovery After Pediatric Traumatic Brain Injury
A traumatic brain injury (TBI) is among the most frequent reasons for neurological impairment in young people. The investigators investigated whether vitamin B12 vs B3 therapy could reduce the severity of traumatic brain injury…
- Trial name
- NCT05958277
- Testing
- Vitamin B3, Vitamin B12
- Where
- Pakistan
- Volunteers
- 300 people
- Sponsor
- KRL Hospital, Islamabad
Chronic Non-specific Low Back Pain
Core Stability Training in Young Adults With Chronic Non-Specific Low Back Pain
Chronic non-specific low back pain is common among young adults and can lead to persistent pain, reduced physical function, decreased muscle strength, and impaired balance, affecting daily activities and quality of life.
- Trial name
- NCT07686237
- Testing
- Swiss ball-based core stability training, Mat-based lumbar muscle exercises
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Guangxi Normal University
Arthroplasty, Replacement Material
Cryoneurolysis Prior to Total Knee Arthroplasty (CRYO-TKA Trial)
Approximately 20-30% of patients experience persistent pain after a Total Knee Arthroplasty (TKA). This study investigates whether percutaneous cryoneurolysis of genicular nerves can reduce pain and improve physical function when…
- Conditions
- Arthroplasty, Replacement Material, Knee Arthritis Osteoarthritis, Knee Arthroplasty, Total
- Trial name
- CRYO-TKA (NCT07425457)
- Testing
- CT-guided Cryoneurolysis of the Genicular Nerves
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital
Cerebral Palsy
Effect of Transcranial Direct Current Stimulation on Hand Recovery and Quality of Life in Hemiparetic Cerebral Palsied Children
Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that may help improve hand function in children with cerebral palsy.
- Trial name
- tDCS-HAND-CP (NCT07746856)
- Testing
- Transcranial Direct Current Stimulation, Functional Task Training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- October 6 University
Cervical Spondylotic Radiculopathy
Clinical Effect of Long Round Needle
The goal of this clinical trial is to test in the clinical effect of long round needle in the treatment of cervical spondylotic radiculopathy, and analyze its safety and its influence on pain and functional recovery.
- Trial name
- NCT05587075
- Testing
- Filiform needle, Long round needle
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Zhanqing Xie
Postoperative Pain Management, Open-heart Surgery
Erector Spinae Plane Block and Postoperative Recovery After Open-Heart Surgery
This prospective randomized controlled clinical trial evaluated the effects of bilateral erector spinae plane block (ESPB) on postoperative systemic functions in adult patients undergoing elective open-heart surgery via median…
- Conditions
- Postoperative Pain Management, Open-heart Surgery, Median Sternotomy, Erector Spinae Plane Block
- Trial name
- ESPB-SYSHEART (NCT07259057)
- Testing
- Erector spinae plane block (ESPB), Intravenous Opioid Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Acute Stroke
BraiN20® Medical Device in Suspected Acute Stroke Patients
Time is Brain company (http://www.tibtimeisbrain.com/about_us/) developed BraiN20®, a medical device to assess the presence and characteristics of the N20 signal of SEP.
- Trial name
- PROMISE-GLOB (NCT06421337)
- Testing
- BraiN20(R)
- Where
- 3 sites in Spain
- Volunteers
- 500 people
- Sponsor
- Alicia Martínez Piñeiro
Aphasia, Stroke
fMRI of Language Recovery Following Stroke in Adults
The purpose of this study is to test the effectiveness of constraint-induced aphasia therapy.
- Trial name
- NCT00843427
- Testing
- CIAT
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Alabama at Birmingham
Thoracic Surgery
Surgical Prehabilitation on Autonomic Nervous System (TUNE)
This study will be a multicenter interventional randomized trial evaluating the effect of a multimodal prehabilitation program on heart rate variability (HRV).
- Trial name
- TUNE (NCT06398301)
- Testing
- Multimodal prehabilitation Program
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Università Vita-Salute San Raffaele
Ligament Injury, Ligament Rupture
Knee Functionality Recovery Indicators in Athletes Submitted to Ligamentoplasty of the Anterior Cruciate Ligament
Anterior cruciate ligament (ACL) injuries are recurrent, especially in sports. There is still no consensus on the characterization of functional indicators in this clinical condition, as well as their correlation with measuring…
- Conditions
- Ligament Injury, Ligament Rupture, Ligament Disorders
- Trial name
- NCT06050005
- Testing
- Diagnostic test through functional tests and comparison of scales applied to participants in the pre-surgical and post-surgical period.
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Postoperative Period, Lung Cancer (Diagnosis)
Investigation of the Effects of Tele-Yoga Training in Individuals With Lung Cancer Undergoing Lung Resection Surgery
This randomized controlled clinical trial aims to evaluate the effects of an 8-week tele-yoga intervention in individuals with lung cancer who have undergone lung resection surgery.
- Trial name
- NCT07001670
- Testing
- Tele-Yoga Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Multiple Sclerosis
Improving Cognitive Recovery in Multiple Sclerosis
This study aims to find out whether an adapted version of an existing cognitive rehabilitation program, CIRCuiTS (https://www.circuitstherapyinfo.com), can be used to improve everyday thinking skills for people with Multiple…
- Trial name
- CIRCuiTS-MS (NCT06877273)
- Testing
- CIRCuiTS-MS
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- King's College London
Postoperative Gastrointestinal Dysfunction (POGD), Postoperative Ileus
Neuromuscular Blocking Agents on Gastrointestinal Function Following Colorectal Surgery
This study is a clinical research project conducted at Xijing Hospital to compare the effects of two different neuromuscular blockade reversal strategies on the recovery of gastrointestinal (GI) function after colorectal surgery.
- Conditions
- Postoperative Gastrointestinal Dysfunction (POGD), Postoperative Ileus, Colorectal Surgery
- Trial name
- NCT07271875
- Testing
- Neostigmine + Atropine, Sugammadex
- Volunteers
- 560 people
- Sponsor
- Xijing Hospital
Adductor Canal Block, Total Knee Replacement Surgery
Coupling of IPACK Block With Adductor Canal Block Versus Adductor Canal Block Alone on Pain, Functional Recovery and Inflammatory Response After Knee Replacement
The aim of this study is to compare the Competency of coupling of IPACK Block with Adductor Canal Block versus Adductor Canal Block Alone on Postoperative Pain after total knee replacement as well as Functional Recovery and…
- Conditions
- Adductor Canal Block, Total Knee Replacement Surgery, Functional Recovery
- Trial name
- NCT07096375
- Testing
- Adductor Canal Block (ACB) + iPACK Block
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Stroke
Neurophysiological and Kinematic Predictors of Response in Chronic Stroke
The purpose of this study is to design a predictive model of stroke recovery based on baseline measurements of arm movement and brain physiology.
- Trial name
- SRT4 (NCT02658630)
- Testing
- Robot + TTT exercise
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- VA Office of Research and Development
Morbid Obesity, Postoperative Pain
Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are…
- Conditions
- Morbid Obesity, Postoperative Pain, Postoperative Bowel Function, Postoperative Ambulation
- Trial name
- NCT01249872
- Testing
- GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE, GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE, GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Patras