Clinical trials: Recovery of Function
Prostate Cancer, Erectile Dysfunction
Erythropoietin to Enhance Recovery of Erectile Function in Men Following Radical Prostatectomy
This research study aims to explore the effectiveness of human erythropoietin versus placebo in promoting the recovery of erectile function in patients undergoing bilateral nerve-sparing radical retropubic prostatectomy for…
- Trial name
- ERECT (NCT00737893)
- Testing
- Erythropoietin (EPO)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Johns Hopkins University
Stroke
Ipsihand Device Use in Stroke Patients to Assess Functional Motor Outcomes
This study aims to evaluate the impact of the Neurolutions Upper Extremity Rehabilitation System, known as IpsiHand, on improving functional motor control for post-stroke patients with hemiparesis.
- Trial name
- NCT04338971
- Testing
- IpsiHand Therapy
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Neurolutions, Inc.
Delayed Graft Function
Envarsus in Delayed Graft Function (E-DGF)
Envarsus XR is an extended release tacrolimus designed to deliver tacrolimus more consistently, thus avoiding large fluctuations of tacrolimus trough levels with Envarsus XR compared to immediate release tacrolimus.
- Trial name
- E-DGF (NCT03864926)
- Testing
- Envarsus XR, Tacrolimus
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Wisconsin, Madison
Traumatic Brain Injury, Depression
Feasibility Study of Duloxetine in the Treatment of Depression in Patients With Traumatic Brain Injury
The primary objective of the study is to compare the efficacy of duloxetine 60 mg by mouth daily with placebo in the prevention of depression associated with mild/moderate traumatic brain injury and to enhance cognitive function.
- Trial name
- Duloxetine (NCT01223001)
- Testing
- Duloxetine, Sugar pill
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Rehabilitation Hospital of Indiana
Heart Failure, Dilated Cardiomyopathy
Harefield Recovery Protocol Study for Patients With Refractory Chronic Heart Failure
The purpose of this study is to evaluate whether patients with chronic heart failure not due to coronary artery disease who require use of a left ventricular assist device (LVAD) for refractory heart failure can recover…
- Trial name
- HARPS (NCT00585546)
- Testing
- clenbuterol
- Where
- 7 sites in United States
- Volunteers
- 18 people
- Sponsor
- Francis D. Pagani
Spinal Cord Injuries
Recovery of Bladder and Sexual Function After Spinal Cord Injury
Bladder and sexual dysfunction consistently ranks as one of the top disorders affecting quality of life after spinal cord injury.
- Trial name
- NCT03036527
- Testing
- Activity-based locomotor training, Activity-based stand training, Activity-based upper arm ergometry
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Head and Neck Neoplasms, Head and Neck Lymphedema
Response to Intermittent Pneumatic Compression Therapy in Head and Neck Cancer-Related Lymphedema
Assessment of lymphatic structure and function pre- and post- treatment and during recovery in head and neck cancer related lymphedema patients using NIR fluorescence lymphatic imaging: Response to ICD therapy in HNC Patients.
- Conditions
- Head and Neck Neoplasms, Head and Neck Lymphedema, Head and Neck Cancer
- Trial name
- NCT02946021
- Testing
- Head and neck garments for pneumatic compression device, NIRFLI with ICG
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Tactile Medical
Obese, Growth Hormone Secretion Abnormality
Growth Hormone Treatment on Phosphocreatine Recovery in Obesity
Obesity is associated with reduced growth hormone (GH) secretion. Reduced GH secretion in obesity is associated with increased cardiovascular disease risk.
- Trial name
- NCT01421589
- Testing
- Growth hormone treatment
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Massachusetts General Hospital
Residual Neuromuscular Blockade
Comparison of the ToFscan and TetraGraph During Recovery of Neuromuscular Function in the Post Anesthesia Care Unit
The aim of this investigation is to compare the performance of two quantitative monitors utilized on post-anesthesia recovering patients.
- Trial name
- NCT03920670
- Testing
- TetraGraph (TG), ToFscan (TS)
- Where
- 3 sites in United States, Hungary
- Volunteers
- 120 people
- Sponsor
- Mayo Clinic
Multiple Sclerosis
Neuroproprioceptive "Facilitation, Inhibition" and Brain Plasticity
This study investigates whether neuroproprioceptive "facilitation, inhibition" physical therapy induces plastic and adaptive processes of the CNS (white matter integrity changes), if they relate to clinical improvement, and…
- Trial name
- NEFAI (NCT04355663)
- Testing
- Motor program activating therapy, Vojta's reflex locomotion, Functional electric stimulation
- Volunteers
- 92 people
- Sponsor
- Charles University, Czech Republic
Incomplete Reversal of Neuromuscular Block
Quality of Recovery After Reversal With Neostigmine or Sugammadex.
This study will compare patient recovery measures after reversal of neuromuscular blockade with neostigmine or sugammadex after surgery.
- Trial name
- NCT02909439
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stony Brook University
Heart Failure With Preserved Ejection Fraction
NMES in HF Patients to Improve Functional Recovery Following Hospitalization
The goal of this research study is to understand whether an at-home exercise program started after hospitalization for HFpEF, and continuing for 4 weeks following discharge from the hospital, can preserve or improve physical…
- Trial name
- NeuHFRecover (NCT05338437)
- Testing
- Neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Vermont Medical Center
Spinal Cord Injuries
Investigation of Brain Functional MRI as an Early Biomarker of Recovery in Individuals With Spinal Cord Injury
Early detection of response to therapeutic intervention is vital, as it will enable early termination of intervention in non-responding patients, prevent unnecessary financial burden, and allow for early changes to the…
- Trial name
- NCT03854214
- Testing
- Functional Electric Stimulation cycling, Passive cycling
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Morbid Obesity, Postoperative Pain
Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are…
- Conditions
- Morbid Obesity, Postoperative Pain, Postoperative Bowel Function, Postoperative Ambulation
- Trial name
- NCT01249872
- Testing
- GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE, GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE, GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Patras
Stroke, Hemiparesis
Electrical Stimulation for Recovery of Hand Function in Chronic Stroke Survivors
Impaired hand function is one of the most frequently persisting consequences of stroke. The purpose of this study is to compare two different treatments -- Contralataterally Controlled Functional Electrical Stimulation (CCFES)…
- Conditions
- Stroke, Hemiparesis, Hemiplegia
- Trial name
- NCT00891319
- Testing
- Electrical stimulator
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- MetroHealth Medical Center
Postoperative Pain, Postoperative Nausea and Vomiting
A Comparison of Targinact vs. Oxycodone on Gut Function After Colorectal Surgery
Two key requirements for discharge from hospital after major abdominal surgery are adequate oral analgesia and resumption of oral nutrition.
- Trial name
- TACS (NCT02109640)
- Testing
- Targinact, Oxycodone, Laparoscopic segmental colectomy
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Edinburgh
Cerebrovascular Stroke
Fast Arm Motor Skill Training in Chronic Stroke Survivors
Every year, almost 800,000 people experience a stroke in the United States, which lead to upper-limb impairments, making recovery of motor function a priority in stroke rehabilitation.
- Trial name
- FAST (NCT05013762)
- Testing
- Fast intervention, Active Monitoring
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Southern California
Coronary Artery Disease
Prasugrel/Clopidogrel Maintenance Dose Washout Study
The primary objective of the study is to describe the cumulative proportion of participants who return to baseline platelet P2Y12 receptor function over time (up to 12 days post last maintenance dose) following discontinuation of…
- Trial name
- NCT01014624
- Testing
- Prasugrel, Clopidogrel
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Daiichi Sankyo
Depression, Quality of Life
RESCUE Stroke Caregiver Website to Enhance Discharge Planning
Aims and Intervention: The long-term goal is to implement stroke caregiver programs that involve low-cost interventions that are sustainable in routine clinical practice.
- Conditions
- Depression, Quality of Life, Self Efficacy, Recovery of Function
- Trial name
- RESCUE (NCT01600131)
- Testing
- Caregiver problem-solving, Standard Care
- Where
- 3 sites in United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury
Recovery of Cardiovascular Function With Epidural Stimulation After Human Spinal Cord Injury
We propose to demonstrate that epidural stimulation (ES) can be used to recover significant levels of autonomic control of cardiovascular and respiratory function as well as the ability to voluntarily control leg movements below…
- Trial name
- NCT02037620
- Testing
- 5-6-5 Specify electrode, Restore Advance Pulse Generator
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Louisville