Clinical trials: Recovery of Postoperative
Pelvic Organ Prolapse (POP), Postoperative Pain
Effect of Paracervical Block on Postoperative Pain After vNOTES Uterosacral Ligament Suspension
This study is a prospective, randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effect of paracervical block on early postoperative pain after vaginal natural orifice transluminal endoscopic…
- Trial name
- vNOTES-PB (NCT07440576)
- Testing
- Bupivacaine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Erkan Gol
Nurse's Role
Effect of Nurse Guided Enhanced Recovery Clinical Pathway on Respiratory Infection
Objectives: Evaluate the effect of a nurse guided enhanced recovery pathway on postoperative respiratory tract infection in Hepatico-Pancreatic -Biliary surgery [ pre-operative patient counselling for postoperative respiratory…
- Trial name
- NCT06812182
- Testing
- nurse guided clinical pathway
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Laryngeal Cancer, Nursing
Perioperative ERAS Based Nursing Intervention for Laryngeal Cancer Patients
To explore the effect of perioperative ERAS based nursing model on the hope level and recovery of patients with laryngeal cancer.
- Trial name
- NCT04174950
- Testing
- Routine nursing care, Perioperative Enhanced Recovery After Surgery (ERAS) Based Nursing Model
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Inguinal Hernia
PRO-RSTAP: Effect of TAP and RS Blocks on Recovery After Inguinal Hernia Surgery (PRO-RSTAP)
Inguinal hernia repair is a common surgical procedure, often performed as day-case surgery. Despite standardized surgical techniques, postoperative pain may delay recovery and occasionally lead to unplanned hospital admission.
- Trial name
- PRO-RSTAP (NCT07423910)
- Testing
- Transversus abdominis plane block (TAP block), Rectus sheath block (active), Ropivacaine
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Tampere University Hospital
Preoperative Anxiety, Emergence Agitation
Effects of Nasal Administration of Dexmedetomidine on Pre-anesthesia Sedation, Intraoperative Brain Electrical Activity, and Incidence of Agitation During Recovery in Children
Pre - operative anxiety and emergence agitation are common issues among pediatric patients, which have various influences on the recovery progress and prognosis of children.
- Trial name
- NCT06896721
- Testing
- Preoperative sedation with dexmedetomidine was administered nasal before surgery, Preoperative sedation with normal saline was administered nasal before surgery
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- Fuzhou Hua
Esophageal Cancer, Gastric Cancer
Octreotide Treatment to Improve Nutritional Recovery After Surgery for Patients with Esophageal or Gastric Cancer
The aim of the study is to clarify whether octreotide therapy can reduce undesired postoperative weight loss, increase health-related quality of life and improve the appetite after surgery for esophageal or gastric cancer.
- Trial name
- OTIS (NCT04871204)
- Testing
- Octreotide Injection
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Fredrik Klevebro
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Postoperative Outcomes Within an Enhanced Recovery After Surgery Protocol (POWER2)
Methods National audit of a 60-day prospective observational cohort in the that the pre-defined postoperative complications at 30 days of follow-up in adult patients electively undergoing hip replacement surgery (HRS) or knee…
- Trial name
- POWER2 (NCT03570944)
- Testing
- HRS, KRS
- Where
- Spain
- Volunteers
- 3,012 people
- Sponsor
- Grupo Español de Rehabilitación Multimodal
Breast Cancer
Effect of Perioperative Low Dose Ketamine on Postoperative Recovery in Patients Undergoing Breast Cancer Surgery
Breast cancer patients often have perioperative emotional disorders such as anxiety and depression, which can lead to poor quality of recovery.This study aims to determine whether ketamine could improve the quality of recovery in…
- Trial name
- NCT03676114
- Testing
- ketamine, Normal saline
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Han Yuan
Oncology
Database for Data Collection in the Context of an Enhanced Recovery After Surgery Program in Oncology Surgery
Enhanced Recovery After Surgery Programs (ERP) includes multimodal approaches of perioperative patient's clinical pathways designed to achieve early recovery after surgery and a decreased length of hospital stay (LOS).
- Trial name
- BDD RAAC (NCT03950011)
- Testing
- Enhanced recovery after surgery program
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Institut Paoli-Calmettes
Bladder Cancer
Multicentral Preventive Antibiotics With Cystectomy Within Enhanced Recovery After Surgery
The current usage of antibiotic prophylaxis (AP) in radical cystectomy (RC) is aimed to reducing the incidence of surgical site infections and incidence of unnecessary prescribing of antibiotics.
- Trial name
- MACS (NCT05392634)
- Testing
- Meropenem 1000 mg, Amoxicillin+clavulanic acid 1200 mg or Cefuroksim 1500mg
- Where
- Russia
- Volunteers
- 98 people
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Cognitive Dysfunction, Emergence Delirium
Effects of Hypothermia on Delayed Neurocognitive Recovery (DNR): an Observational Trial Among Patients Undergoing Cardiac-Surgery
Post-operative cognitive dysfunction is a common disease in patient undergoing general anaesthesia, especially in older patients.
- Conditions
- Cognitive Dysfunction, Emergence Delirium, Hypothermia
- Trial name
- DNR (NCT03636074)
- Testing
- Hypothermia during Extracorporeal Circulation
- Where
- Italy
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Padova
Cesarean Section, Cesarean Section Pain
Effects of Music Therapy, Breathing Exercises, and Virtual Reality on Obstetric Recovery, Pain, and Gastrointestinal Symptoms After Cesarean Section
Cesarean section is a common surgical procedure performed to deliver a baby when vaginal birth may pose risks to the mother or infant.
- Conditions
- Cesarean Section, Cesarean Section Pain, Obstetric Recovery, Gastrointestinal Symptoms
- Trial name
- NCT07551401
- Testing
- Music Therapy, Breathing Exercises, Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people
- Sponsor
- Selcuk University
Enhanced Recovery After Surgery, Open Heart Surgery
The Effect of Advanced Improvement Program (ERAS) on Postoperative Outcomes in Patients Undergoing Open Heart Surgery
Investigation of the effect of Enhanced Recovery After Surgery (ERAS) program on postoperative results of patients operated for open heart surgery.
- Trial name
- NCT03799965
- Testing
- ERAS (Enhanced Recovery After Surgery ) are evaluated, ERAS are not evaluated
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Desflurane Anesthesia, Postoperative Recovery
The Quality of Recovery From General Anesthesia With Desflurane for Fundus Surgery
The goal of this clinical trials to study and compare the effects of "desflurane with remifentanil anesthesia (study group)" and "sevoflurane with remifentanil anesthesia (control group)" for elective fundus surgery anesthesia.
- Trial name
- NCT06241131
- Testing
- Desflurane Inhalant Product
- Volunteers
- 220 people
- Sponsor
- Sichuan Provincial People's Hospital
Orthognathic Surgical Procedures
Effects of Low Medial Ramus Osteotomy on Neurosensorial Recovery During Post-Operative Period
The aim of this study is to compare the post-operative neurosensorial disturbances of Hunsuck-Epkerr and "low and short medial osteotomy" modifications of sagittal split ramus osteotomy.
- Trial name
- NCT06662331
- Testing
- Bilateral Sagittal Split Osteotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ali Törel Saygı
Obesity, Pain, Postoperative
Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity Surgery
The opioid consumption has exploded in the western world, and for some patient populations such as obese patients, patients with sleep apnoea or patients undergoing cancer treatment, opioid-sparing/ opioid-free strategies could…
- Trial name
- OS-PCC (NCT03756961)
- Testing
- Dexmedetomidine, Person-centred care (PCC), Esketamine
- Where
- 2 sites in Sweden
- Volunteers
- 220 people
- Sponsor
- Göteborg University
Pain, Postoperative, Postoperative Ileus
Effect of Tegileridine on Postoperative Bowel Function Recovery in Abdominal Surgery
Title: Effect of Tegileridine on Postoperative Bowel Function Recovery in Abdominal Surgery: A Multicenter, Randomized, Controlled Trial The goal of this clinical trial is to evaluate the effectiveness and safety of tegileridine…
- Trial name
- NCT07412223
- Testing
- Tegileridine, Morphine
- Where
- 3 sites in China
- Volunteers
- 152 people
- Sponsor
- Xiangya Hospital of Central South University
Thyroidectomy
Nurse-Led First-Night Preparation After Thyroidectomy
This study evaluates the effect of a nurse-led "first-night preparation" intervention on quality of recovery, sleep quality, and symptom management in patients undergoing elective total thyroidectomy.
- Trial name
- NCT07849946
- Testing
- Nurse-Led First-Night Preparation Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Volkan Gokmen
Anesthesia, Spinal, Orthopedic Procedures
Comparison of Low-Dose Versus Standard-Dose Hyperbaric Bupivacaine in Spinal Anesthesia
The goal of this randomized controlled trial is to determine whether low-dose hyperbaric bupivacaine provides better hemodynamic stability and postoperative recovery compared with standard-dose hyperbaric bupivacaine in elderly…
- Conditions
- Anesthesia, Spinal, Orthopedic Procedures, Postoperative Recovery in Elderly Patients, Hemodynamics
- Trial name
- NCT07684989
- Testing
- Low-Dose Hyperbaric Bupivacaine, Standard-Dose Hyperbaric Bupivacaine
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Mayo Hospital Lahore
Ileus
Acupuncture and Post-Operative Ileus
Postoperative ileus, the transient cessation of normal bowel function, is a universal aspect of colon surgery. Its occurrence may lead to increased patient discomfort and additional time and cost to hospital stay.
- Trial name
- NCT00655317
- Testing
- Acupuncture
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- Mayo Clinic