Clinical trials: Recovery of Postoperative
Enhanced Recovery After Surgery
Comparison of Postoperative Recovery Between TIVA and Inhalation Agent
This prospective, randomized, single-blinded study is designed to compare the postoperative quality of recovery between propofol based total intravenous anesthesia and desflurane in patients undergoing minimally invasive…
- Trial name
- NCT04447105
- Testing
- total intravenous anesthesia with propofol, inhalation anesthesia with desflurane
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Exercise, Breast Neoplasm Female
Prehabilitation and RecOVERy From Surgery for Breast Cancer Study
Background and study aims: Nine out of ten women experience some negative effects due to their disease or its treatment such as anxiety, depression, weight gain and low quality of life.
- Trial name
- PROVERB (NCT05901142)
- Testing
- Exercise-based multi-phasic, multi-modal intervention
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Analgesia, Postoperative Pain, Acute
Effects of Pericapsular Nerve Group Block on Postoperative Recovery for Total Hip Arthroplasty
The hypothesis of this study is that patients who undergo PENG block in before Total Hip Artroplasthy (THA) surgery with spinal anesthesia will have reduced postoperative pain scores, less need for opioid analgesics and earlier…
- Trial name
- NCT06183528
- Testing
- Pericapsular Nerve Group (PENG) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Umraniye Education and Research Hospital
Laparoscopic Cholecystectomy, Patient Education
Video-Assisted Education After Laparoscopic Cholecystectomy
Brief Summary: This randomized controlled trial aims to evaluate the effects of video-assisted preoperative education on postoperative physiological parameters and recovery outcomes in patients undergoing laparoscopic…
- Trial name
- VAE-LC (NCT07277036)
- Testing
- Video-Assisted Patient Education
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Izmir Tinaztepe University
Elderly, Noncardiac Surgery
Impact of Esketamine on Delayed Neurocognitive Recovery in Older Patients
Esketamine is frequently used during the perioperative period for supplemental analgesia. Small sample size trials showed that subanesthetic dose esketamine may decrease postoperative neurocognitive complications.
- Conditions
- Elderly, Noncardiac Surgery, Delayed Neurocognitive Recovery, Postoperative Delirium
- Trial name
- NCT07523334
- Testing
- Esketamine 1, Esketamine 2, Esketamine 3
- Where
- 2 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Gynecologic Surgical Procedures
Comparing Intra-Abdominal Pressure During Gynecologic Laparoscopy
The goal of this clinical trial is to learn if the level of intra-abdominal pressure during benign gynecologic laparoscopic surgery impacts postoperative pain.
- Trial name
- NCT07221487
- Testing
- abdominal pressure
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Nassau University Medical Center
Emergence Agitation, Vocal Cord Polyps
Intranasal Dexmedetomidine Combined With Esketamine for Emergence Quality After Suspension Laryngoscopy
This is a single-center, prospective, single-blinded, randomized controlled trial conducted at The First Hospital of Jilin University.
- Trial name
- NCT07880938
- Testing
- Dexmedetomidin, Esketamine
- Where
- China
- Volunteers
- 134 people
- Sponsor
- The First Hospital of Jilin University
Postoperative Pain Management in Total Knee Arthroplasty
Dexmedetomidine as an Adjunct to Periarticular Ropivacaine in Total Knee Replacement: A Pilot Randomised Controlled Trial
This study aims to evaluate whether adding dexmedetomidine to ropivacaine-based periarticular infiltration (PAI) improves postoperative pain control in patients undergoing total knee replacement (TKR).
- Trial name
- NCT07176065
- Testing
- Ropivacaine + saline solution, Ropivacaine + Dexmedetomidine
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- University of Malaya
Dexmedetomidine, Robotic Surgery
The Effect of Dexmedetomidine on Postoperative Cognitive Function in Geriatric Patients
In pelvic surgeries, using laparoscopic surgical procedures provides advantages such as reduced postoperative pain and complications, early mobilization, shorter hospital stays, lower costs, better cosmetic outcomes, and faster…
- Conditions
- Dexmedetomidine, Robotic Surgery, Geriatric Patients
- Trial name
- NCT07047898
- Testing
- The group receiving dexmedetomidine infusion, The group not receiving dexmedetomidine infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Cognitive Recovery, Sedation
Effects of Different Sedation Techniques on Early Cognitive Recovery After Ambulatory Gynecologic Surgery
This prospective, randomized, double-blind clinical trial aims to compare the effects of three commonly used sedoanalgesia regimens on early cognitive recovery in patients undergoing ambulatory gynecologic surgery (dilatation and…
- Conditions
- Cognitive Recovery, Sedation, Ambulatory Gynecologic Surgery, Postoperative Recovery
- Trial name
- SEDCOG (NCT07267377)
- Testing
- Propofol-Fentanyl, Ketamine-Fentanyl, Propofol + Ketamine + Fentanyl (Ketofol)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sait Fatih Öner
Total Knee Arthoplasty, Knee Pain
TENS in Post-operative Total Knee Arthroplasty Recovery and Intra-venous Analgesics Requirement
Total knee arthroplasty (TKA) is among the major advancements for the treatment of knee pain and improvement of physical function when conservative management fails to comply with.
- Trial name
- NCT05470244
- Testing
- Routine Physical Therapy and Intra-venous analgesic regimen, Transcutaneous Electrical Nerve Stimulation along with Routine Physical Therapy and Intra-venous analgesic regimen
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Coronary Artery Disease (CAD), Coronary Artery Bypass Graft (CABG)
Effects of a Recovery-Promoting Program in Patients Undergoing CABG Surgery
Patients undergoing coronary artery bypass graft (CABG) surgery often experience physical limitations, psychological stress, and challenges during recovery after hospital discharge.
- Conditions
- Coronary Artery Disease (CAD), Coronary Artery Bypass Graft (CABG), Postoperative Recovery
- Trial name
- NCT07392021
- Testing
- Recovery Promotion Program for CABG patients, Standard Postoperative CABG Care
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Knee Surgery, Kinesiophobia (Fear of Movement)
Effects of Music Listening and Relaxation Interventions on Postoperative Recovery After Knee Surgery
This study aims to evaluate whether listening to music and using Emotional Freedom Techniques (EFT) can help patients recover better after knee arthroscopy.
- Conditions
- Knee Surgery, Kinesiophobia (Fear of Movement), Postoperative Pain, Arthroscopic Surgery
- Trial name
- EFT (NCT07530614)
- Testing
- Emotional Freedom Techniques, listening music
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Arzum ÇELİK BEKLEVİÇ
Genital Neoplasm Malignant Female
Adapted ERAS in Gynecologic Oncology Surgery
Background: In recent decades, the new concept of Enhanced Recovery After Surgery (ERAS) program has been well accepted in the fields of gynecologic surgery.
- Trial name
- NCT04201626
- Testing
- Adapted ERAS
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Chiang Mai University
Postoperative Recovery in Elderly Patients, Quality of Recovery After Elective Surgery
Postoperative Recovery in Elderly Patients Assessed With QoR-15E
Postoperative recovery in elderly patients is an important part of the surgical process and affects how patients feel after surgery.
- Conditions
- Postoperative Recovery in Elderly Patients, Quality of Recovery After Elective Surgery, Perioperative Care Outcomes in Older Adults
- Trial name
- PQoRE (NCT07505758)
- Testing
- QoR-15E questionnaire., Clinical Frailty Scale, Confusional Assessment Method
- Where
- 4 sites in Spain
- Volunteers
- 600 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Intravenous Lidocaine, Laparoscopic Surgery
Intravenous Lidocaine Plus Port-Site Ropivacaine for Recovery After Laparoscopic Surgery
This randomized controlled trial evaluates whether perioperative intravenous lidocaine infusion, combined with port-site ropivacaine infiltration, improves postoperative recovery after laparoscopic abdominal surgery.
- Conditions
- Intravenous Lidocaine, Laparoscopic Surgery, Post Operative Recovery, Local Anaesthetic Systemic Toxicity
- Trial name
- LivQor (NCT07414706)
- Testing
- Procedure/Standard care, ropivacaine, Lidocaine (intravenous infusion, perioperative)
- Where
- France
- Volunteers
- 182 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Systemic Inflammatory Response Syndrome
Can Biomarkers Aid in the Prediction of Postoperative Pain and Circulatory Instability After Major Abdominal Surgery?
Patients undergoing major surgery are exposed to extensive damage of tissues, which induces widespread activation of the inflammatory system, called 'systemic inflammatory response syndrome' (SIRS).This activation of the…
- Trial name
- NCT02563652
- Where
- 2 sites in Italy, Norway
- Volunteers
- 101 people
- Sponsor
- St. Olavs Hospital
Spine Surgery
Lidocaine Infusion With ANI Monitoring in Spine Surgery.
To evaluate the analgesic effect of intraoperative continuous lidocaine infusion (1.5 mg/kg/h (ideal body weight)) in combination of analgesia nociception index and depth of anesthesia monitors guided anesthetics adjustment on…
- Trial name
- NCT05103215
- Testing
- Lidocaine HCl 2%, Normal saline
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Obesity, Premature Recovery From Anesthesia
Armodafinil (Nuvigil), Postoperative Recovery of OSA (Obstructive Sleep Apnea) and Obese Patients
Obstructive sleep apnea (OSA) and obesity is associated with increased perioperative morbidity and mortality. This group of patients is at risk of perioperative desaturations which can be worsened by perioperative sedatives and…
- Trial name
- NCT02478580
- Testing
- Nuvigil
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Texas Southwestern Medical Center
Pain, Postoperative
Biobehavioral Recovery From Surgery and Anesthesia
Reducing postoperative pain leads to increased patient comfort and facilitates speedy recovery and discharge from the hospital following surgery.
- Trial name
- NCT00176696
- Testing
- Use of FACE monitor and BIS monitor
- Volunteers
- 20 people
- Sponsor
- University of Medicine and Dentistry of New Jersey