Clinical trials: Recovery of Postoperative
Whey Protein, Thyroid Neoplasms
Whey Protein and Carbohydrates in ERAS for Recovery After Thyroidectomy: A Cohort Study
Exploring the effects of whey protein combined with carbohydrates in an Enhanced Recovery After Surgery (ERAS) protocol on the postoperative recovery of thyroid cancer patients undergoing lateral neck dissection, aiming to…
- Conditions
- Whey Protein, Thyroid Neoplasms, Neck Dislocation, Enhanced Recovery After Surgery
- Trial name
- NCT06607965
- Testing
- Whey Protein and Carbohydrates
- Where
- China
- Volunteers
- 127 people
- Sponsor
- Chongqing General Hospital
Laparoscopic Cholecystectomy, Postoperative Quality of Recovery
Effect of Preoperative Melatonin on Quality of Recovery After Elective Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is one of the most commonly performed abdominal surgical procedures worldwide. Although the widespread implementation of Enhanced Recovery after Surgery (ERAS) protocols has improved perioperative…
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Quality of Recovery, Preoperative Anxiety, Postoperative Sleep Quality
- Trial name
- MEL-REC (NCT07553143)
- Testing
- Melatonin (N-acetyl-5-methoxytryptamine)
- Where
- Bangladesh
- Volunteers
- 84 people
- Sponsor
- Armed Forces Medical Institute Bangladesh
Older Adults, Surgery
Perioperative Transcranial Photobiomodulation and Delayed Neurocognitive Recovery in Older Patients
Delayed neurocognitive recovery is a common neurocognitive complication in older patients after surgery, especially those with preoperative neurocognitive decline.
- Conditions
- Older Adults, Surgery, Transcranial Photobiomodulation, Delayed Neurocognitive Recovery
- Trial name
- NCT07736092
- Testing
- Transcranial photobiomodulation therapy, Transcranial pseudo-photobiomodulation
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Acute Pain
Etoricoxib for Postoperative Pain After Thyroid Surgery
The purpose of the study is evaluate the analgesic efficacy and safety profile of the Cox-2 specific analgesic Etoricoxib (arcoxia®) when administrated pre and postoperatively for controlling pain in adult patients undergoing…
- Trial name
- NCT00935116
- Testing
- etoricoxib
- Volunteers
- 70 people
- Sponsor
- Hospital Padre Hurtado
Neuromuscular Block, Renal Transplant Donor of Left Kidney
Deep Versus Moderate Muscle Relaxation During Laparoscopic Donor Nephrectomy in Enhancing Postoperative Recovery
Postoperative recovery after live donor nephrectomy (LDN) is largely determined by the consequences of postoperative pain and analgesia consumptions.
- Conditions
- Neuromuscular Block, Renal Transplant Donor of Left Kidney, Renal Transplant Donor of Right Kidney, Surgery
- Trial name
- RELAX (NCT02838134)
- Testing
- Rocuronium, No additional Rocuronium
- Where
- 2 sites in Netherlands
- Volunteers
- 101 people
- Sponsor
- Radboud University Medical Center
Elderly, Noncardiac Surgery
Impact of Esketamine on Delayed Neurocognitive Recovery in Older Patients
Esketamine is frequently used during the perioperative period for supplemental analgesia. Small sample size trials showed that subanesthetic dose esketamine may decrease postoperative neurocognitive complications.
- Conditions
- Elderly, Noncardiac Surgery, Delayed Neurocognitive Recovery, Postoperative Delirium
- Trial name
- NCT07523334
- Testing
- Esketamine 1, Esketamine 2, Esketamine 3
- Where
- 2 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Arthroplasty, Replacement, Knee, Pain, Postoperative
Continuous Adductor Canal Infusion vs. Single-injection Adductor Canal Block for Total Knee Arthroplasty
Multimodal analgesia (MMA) has been endorsed to improve postoperative analgesia and functional activity after surgery, and integrating regional analgesia to reduce the consumption of opioid has also been used in postoperative…
- Conditions
- Arthroplasty, Replacement, Knee, Pain, Postoperative, Multimodal Analgesia
- Trial name
- NCT05669898
- Testing
- Pain scores (numerical rating scale at rest and motion): will be assessed with numerical rating scale at both rest and motion on both knees., Brief Pain Inventory (Short Form), WOMAC Osteoarthritis index, and Lower extremity functional scale, Rehabilitation physiotherapy
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Ventilatory Depression, Postoperative Respiratory Failure
The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia
In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting from extubation of the trachea.
- Trial name
- NCT05379673
- Testing
- Oxygen Gas for Inhalation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Post Operative Complications, Pneumonia
Inpatient ICOUGH RECOVERY App Version 2.0
This pilot study will evaluate how well version 2 of the ICOUGH app, a bed-side mobile app increases patients' adherence to a postoperative protocol called ICOUGH.
- Trial name
- ICOUGH (NCT03599037)
- Testing
- ICOUGH Recovery App v2.0
- Where
- United States
- Sponsor
- Boston Medical Center
Knee Arthroplasty, Total, Partial Knee Arthroplasty
Opioid Reduction and Enhanced Recovery in Orthopaedic Surgery (OREOS)-Knee
Knee replacements are the second most common surgery in Canada. Most patients recover very well but research consistently shows that 1 in 5 patients still have pain many months after surgery.
- Conditions
- Knee Arthroplasty, Total, Partial Knee Arthroplasty, Chronic Pain, Postoperative, Osteoarthritis (OA) of the Knee
- Trial name
- OREOS-K (NCT07895472)
- Testing
- Standard care, Multicomponent opioid reduction and pain management pathway
- Volunteers
- 170 people
- Sponsor
- McMaster University
Mastectomy, Pain, Postoperative
Erector Spina Plane Block vs Serratus Anterior Plane Block for Postoperative Mastectomy Pain
The aim of this study is to compare the efficiency of serratus anterior plane block and erector spina plane block on analgesic consumption, postoperative pain and patient's satisfaction and recovery quality in patients undergoing…
- Conditions
- Mastectomy, Pain, Postoperative, Recovery Period, Anesthesia
- Trial name
- NCT04296188
- Testing
- serratus anterior plane block, erector spina plane block
- Volunteers
- 60 people
- Sponsor
- Tokat Gaziosmanpasa University
Postoperative Pain
Postoperative Analgesia and Recovery Quality in Total Thyroidectomy
This prospective observational study evaluates the association between postoperative analgesic approaches and recovery outcomes in patients undergoing elective total thyroidectomy.
- Trial name
- NCT07547124
- Testing
- Cervical Plexus Block
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istinye University
Gastrointestinal Surgery, Mirabilite
External Application of Mirabilite to Promote Recovery in Patients After Gastrointestinal Surgery
This study evaluates the efficacy and safety of topical Mirabilite (sodium sulfate) application for managing postoperative outcomes in patients undergoing gastrointestinal cancer surgery.
- Conditions
- Gastrointestinal Surgery, Mirabilite, Surgical Site Infection, Postoperative Gastrointestinal Dysfunction
- Trial name
- NCT06696729
- Testing
- Topical Mirabilite Application for Postoperative Gastrointestinal Patients, Standard Postoperative Care for Gastrointestinal Patients
- Where
- China
- Volunteers
- 301 people
- Sponsor
- Nanchang University
Knee Arthroscopy
Outpatient Total Knee Arthroscopy (TKA): Comparison of Postoperative Recovery Versus a Conventional Hospitalization
Outpatient TKA is a controversial topic due to concerns about its safety as an outpatient procedure, and remains a marginal procedure.
- Trial name
- PTG (NCT07276061)
- Where
- France
- Volunteers
- 440 people
- Sponsor
- University Hospital, Strasbourg, France
Colorectal Surgery, Recovery of Function
Enhanced Recovery Program in Laparoscopic Colorectal Surgery: an Observational Controlled Trial
Background: A few randomized clinical trials and meta-analysis provide evidence for enhanced recovery programs (ERPs) in colorectal surgery.
- Trial name
- NCT04378465
- Testing
- Enhanced Recovery Program (ERP)
- Volunteers
- 200 people
- Sponsor
- University Hospital of Ferrara
Head and Neck Neoplasms
HFHS-1801-A Pilot Study of Immunotherapy As Consolidation Therapy for Patients with Recurrent Head and Neck Cancer
The study is a pilot study to explore the feasibility and efficacy of immunotherapy following salvage surgery for recurrent head and neck cancer.
- Trial name
- NCT04188951
- Testing
- Pembrolizumab 25 MG/1 ML Intravenous Solution [KEYTRUDA]
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Henry Ford Health System
Cranial Neurosurgery
Heart Rate Variability and Processed EEG Features as Predictors of Postoperative Outcomes After Cranial Neurosurgery
Patients undergoing cranial neurosurgery face a high-risk postoperative period, particularly during emergence from anesthesia and early recovery in the post-anesthesia care unit (PACU).
- Trial name
- HERO-PACU (NCT07443072)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Emergence Delirium
The Effect of Magnesium Supplementation During General Anesthesia on the Quality of Postoperative Recovery in Children
Evaluation of prevention of emergence delirium and analgesic effect of magnesium on children
- Trial name
- NCT03132701
- Testing
- Magnesium, Saline
- Where
- South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Postoperative Pain, Postoperative Ileus
Effect of Liposomal Bupivacaine TAPB Combined With Oxycodone PCIA on Postoperative Gastrointestinal Recovery in Patients Undergoing Major Abdominal Surgery
Rationale and Objective: The purpose of this study is to evaluate the clinical efficacy and safety of a novel multimodal analgesia regimen, combining transversus abdominis plane block (TAPB) with patient-controlled intravenous…
- Trial name
- NCT07651722
- Testing
- ropivacaine hydrochloride, Liposomal bupivacaine (LB), Sufentanil citrate
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Tianjin First Central Hospital
Pain, Postoperative
Exploring the Effects of Transcutaneous Electrical Acupoint Stimulation Therapy on Patients After Video-Assisted Thoracoscopic Surgery
Thoracic surgery is known to be one of the most painful types of surgery. If acute postoperative pain is not properly managed, there is a high risk that it may develop into clinically significant chronic pain within six months…
- Trial name
- NCT07287657
- Testing
- Standard Analgesia, Transcutaneous Electrical Nerve Stimulation (TENS), Transcutaneous Electrical Acupoint Stimulation (TEAS)
- Where
- Taiwan
- Volunteers
- 96 people
- Sponsor
- Buddhist Tzu Chi General Hospital
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