Clinical trials: Recovery of Postoperative
Hip Arthroplasty, Total, Prevention of Venous Thromboembolism
ENhanced Recovery and ABbreviated LEngth of Anticoagulation for Thromboprophylaxis After Primary Hip Arthroplasty
Surgical hip replacement (total hip arthroplasty, THA) is associated with a high risk of venous thromboembolism, but the appropriate duration of postoperative medical thromboprophylaxis ("anticoagulation") remains highly…
- Trial name
- ENABLE-Hip (NCT06611319)
- Testing
- Prevention of Venous Thromboembolism
- Where
- 6 sites in Austria, Germany
- Volunteers
- 2,932 people
- Sponsor
- Prof. Stavros Konstantinides, MD
Analgesia, Pain, Postoperative
Effects of Intraoperative Magnesium Sulfate on Perioperative Pain Relief After Spine Surgery
The treatment of postoperative pain is increasingly based on a multimodal approach and although opioids remain the drug of choice, they are often used in combination with other analgesics (paracetamol, cyclooxygenase inhibitors…
- Conditions
- Analgesia, Pain, Postoperative, Spine Disease
- Trial name
- NCT04161729
- Testing
- Magnesium Sulfate, Isotonic saline 0.9%
- Where
- Greece
- Volunteers
- 74 people
- Sponsor
- Aristotle University Of Thessaloniki
Postoperative Recovery
Does Erector Spinal Block Improve Quality of Recovery After Laparoscopic Cholecystectomy
The primary aim of this prospective, randomized study is to evaluate the effect of erector spinae block (ESP) on quality of recovery with the QoR-40 questionnaire in patients undergoing elective laparoscopic cholecystectomy.
- Trial name
- NCT04112394
- Testing
- local anesthetic injection, Standard perioperative and postoperative analgesia protocol.
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Opioid Use, Pain, Acute
Pre-post Erector Spine Plane Block-spinal Surgery
Spinal surgery patients generally have chronic pain in the preoperative period and are exposed to widespread and severe acute pain postoperatively.
- Trial name
- pre-post-esp (NCT06215053)
- Testing
- erector spine plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Aydin Adnan Menderes University
Pain Postoperative
Sngception and Pain in Spine Enhanced Recovery After Surgery (ERAS) Pathways
Enhanced recovery after surgery (ERAS) is a recognized, evidence-based and patient-centered clinical pathway that has an array of benefits.
- Trial name
- NCT05885802
- Testing
- No specific intervention other than routine anesthesia protocol
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Anesthesia, Postoperative Pain
The Effect of Ultrasound-guided Erector Spinae Block and Intraoperative Intercostal Nerve Block on Postoperative Analgesia in Thoracic Surgery
This study aims to compare the effect of ultrasound-guided erector spinae plane block and interthoracic intercostal nerve block in thoracic surgery.
- Conditions
- Anesthesia, Postoperative Pain, Ultrasound Therapy; Complications
- Trial name
- NCT04581616
- Testing
- Intrathoracic Intercostal Nerve Block, Erector Spinae Plane Block
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Postoperative Oral Carbohydrates, Postoperative Recovery
Effect of Early Postoperative Oral Carbohydrate on Postoperative Recovery of the Unilateral Knee Arthroplasty
To evaluate the effect of early postoperative oral carbohydrate on postoperative recovery of the unilateral knee arthroplasty
- Conditions
- Postoperative Oral Carbohydrates, Postoperative Recovery, Unilateral Knee Arthroplasty
- Trial name
- NCT05867264
- Testing
- Early drinking water, Early consumption of carbohydrates, Late feeding group
- Volunteers
- 672 people, healthy volunteers welcome
- Sponsor
- Hongwei Shi
Rectal Cancer, Low Anterior Resection Syndrome
The Effects of Kegel Exercise Combined With Biofeedback Therapy on Bowel Function Recovery, Emotional Distress, and Quality of Life in Patients Following Low Anterior Resection for Rectal Cancer
This randomized controlled trial aims to evaluate the effects of combining Kegel exercise with a single biofeedback session on bowel function, emotional distress, and quality of life in patients who have undergone low anterior…
- Conditions
- Rectal Cancer, Low Anterior Resection Syndrome, LARS - Low Anterior Resection Syndrome
- Trial name
- BFT in LARS (NCT07253298)
- Testing
- Kegel Exercise with Biofeedback, Kegel Exercise Only
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- National Taiwan University Hospital
Gastrointestinal Surgery
Preoperative Oral Carbohydrate and Postoperative Recovery in Diabetic Patients
For non-diabetic patients undergoing gastrointestinal surgery, preoperative oral carbohydrate improves postoperative recovery. The purpose of this pilot study is to investigate the impact of preoperative oral carbohydrate…
- Trial name
- NCT03204344
- Testing
- Oral carbohydrate (Outfast), Routine fasting
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Dong-Xin Wang
Transplant Complication, Diabetic Nephropathy
Enhanced Recovery After Surgery for SPK Transplantation Recipients
108 patients underwent elective SPK surgery were randomly divided into ERAS group (E) and routine care group (T). The ERAS group was consisted of evidenced-based systematic optimization approaches, while the control group…
- Conditions
- Transplant Complication, Diabetic Nephropathy, Perioperative/Postoperative Complications
- Trial name
- NCT06095544
- Testing
- Enhanced recovery for SPK recipients
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Anesthesia, Anxiety
Anxiolytic Effectiveness of Virtual Reality Glasses in Surgery
Regional anesthesia allows surgery without affecting the patient's level of consciousness.However, this may cause anxiety in some patients.In previous research, scientists have tried to prevent anxiety with non-pharmacological…
- Conditions
- Anesthesia, Anxiety, Postoperative Pain, Postoperative Recovery
- Trial name
- NCT06244654
- Testing
- Oculus Quest 2 VR virtual reality glasses and wired over-ear headphones, No VR
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Ankara City Hospital Bilkent
Hysterectomy
Effect of Enhanced Recovery After Surgery (ERAS) on Inflammatory Response After Planned Abdominal Hysterectomy
The aim of study is to determine effect of enhanced recovery after surgery (ERAS) on inflammatory response after abdominal hysterectomy.
- Trial name
- GERAS (NCT01747005)
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Antypin Eduard Eduardovich
Morbid Obesity, Perioperative Hemorrhage
Effect of Tranexamic Acid on Bleeding After Bariatric Surgery
Postoperative bleeding is an important complication of bariatric surgery and may lead to increased morbidity, prolonged hospitalization, and higher healthcare costs.
- Conditions
- Morbid Obesity, Perioperative Hemorrhage, Obesity, Tranexamic Acid
- Trial name
- TXA-BARI (NCT07754396)
- Where
- Greece
- Volunteers
- 140 people
- Sponsor
- G.Gennimatas General Hospital
Postoperative Pain, Acute Pain
M-TAPA Block for Analgesia After Open-Heart Surgery
Postoperative pain following open-heart surgery is primarily caused by median sternotomy, although additional contributors include costovertebral joint stress related to sternal retraction and the presence of chest wall and…
- Trial name
- NCT07232979
- Testing
- M TAPA block, Parasternal blocks, Local infiltration
- Volunteers
- 80 people
- Sponsor
- Bursa City Hospital
Postoperative Pain, Ventral Hernia
Mesh Fixation With Intraperitoneal Tisseel
The purpose of this study is to determine whether mesh fixation in laparoscopic umbilical hernia repair with fibrin glue is superior to tacks in terms of postoperative pain and recovery.
- Trial name
- MEFIXIT (NCT00842842)
- Testing
- tack fixation of mesh, glue fixation of mesh
- Where
- 4 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Herlev Hospital
Postoperative; Dysfunction Following Cardiac Surgery
My Cardiac Recovery (MyCaRe): A Pilot RCT.
MyCardiacRecovery (MyCaRe) is an interactive platform that includes a standardized educational format and interactive tracking (wound healing and activity progression using photo capabilities and Fitbit Inspire 2 accelerometer)…
- Trial name
- MyCaRe (NCT02778165)
- Testing
- MyCaRe (my cardiac recovery Android application)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Postoperative Pain
The Effect of Intermittent Cryotherapy Exposure on Patients' Quality of Recovery After Surgery
"Cryotherapy", or cold therapy, can include the use of gel packs, ice bags, ice baths, whole body chambers, and cold aerosol sprays.
- Trial name
- ICE (NCT04564963)
- Testing
- Cryotherapy
- Where
- 3 sites in Canada
- Volunteers
- 196 people
- Sponsor
- Sunnybrook Health Sciences Centre
Anastomotic Leak
PREDICS Study: PCT Reveals Early Dehiscence in Colorectal Surgery
Procalcitonin (PCT) is a biomarker used to monitor serious bacterial infections and guide antibiotic therapy. Anastomotic leak (AL) after colorectal surgery is a severe complication associated with relevant short and long-term…
- Trial name
- PREDICS (NCT01817647)
- Testing
- Colorectal surgery
- Where
- Italy
- Volunteers
- 504 people
- Sponsor
- University of Roma La Sapienza
Coronary Artery Disease, Postoperative Care
CABG-AI-Supported Discharge Education
This randomized controlled trial will evaluate the effectiveness of artificial intelligence-supported individualized discharge education for patients undergoing coronary artery bypass graft (CABG) surgery.
- Conditions
- Coronary Artery Disease, Postoperative Care, Patient Discharge, Recovery of Function
- Trial name
- AI-D-E-CABG (NCT07503678)
- Testing
- AI-Supported Individualized Discharge Education, Standard Discharge Education
- Volunteers
- 128 people
- Sponsor
- Hasan Kalyoncu University
Delirium, Anesthesia; Adverse Effect
Assessment of Immediate Postoperative Delirium (IPD) in Adult Patients: Incidence and Etiologic Factors
Delirium is considered to be acute failure of central nervous system. It is acute confusional state characterized by decline from baseline mental level, attention deficit and disorganized thinking.
- Trial name
- AIPDAP (NCT03967496)
- Testing
- Types of Anesthesia, Access of Surgery, Comorbidities
- Where
- Oman
- Volunteers
- 402 people
- Sponsor
- Sultan Qaboos University
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