Clinical trials: Recovery of Postoperative
Esophageal Cancer, Complication, Postoperative
The Effects on Major Organ Complications on Esophagectomy of New Anesthetic ERAS Strategy: a Prospective Investigation
The goals of this study are to testify the effectiveness on enhancement recovery by new anesthetic ERAS (Enhanced recovery after surgery) strategy.
- Conditions
- Esophageal Cancer, Complication, Postoperative, Anesthesia
- Trial name
- ERAS (NCT03176680)
- Testing
- Fluid therapy optimization
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Gastrointestinal Dysfunction
Effects of Intraoperative Stimulation of Acupoints on Postoperative Gastrointestinal Motility Recovery
1. Research name: Effects of intraoperative stimulation of acupoints on postoperative gastrointestinal motility recovery in patients undergoing non-gastrointestinal abdominal surgery. 2. Research center: Multicenter research 3.
- Trial name
- NCT03724656
- Testing
- acupuncture treatment
- Volunteers
- 600 people
- Sponsor
- Tianjin Nankai Hospital
Urinary Bladder Neoplasms
Study Comparing Open Radical Cystectomy With Robot-assisted Cystectomy in Patients With Bladder Cancer
The purpose of the study to compare two established methods of radical cystectomy (RC) in patients with bladder cancer. The participants will be treated under conditions in alignment with up-to-date guidelines and care.
- Trial name
- NCT03977831
- Testing
- Radical Cystectomy
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postoperative Analgesia
Intravenous Paracetamol in Combination With Caudal Ropivacaine
To investigate whether the addition of intravenous paracetamol with caudal ropivacaine leads to better quality of postoperative recovery in patients undergoing hypospadius repair than caudal ropivacaine alone.
- Trial name
- NCT03781505
- Testing
- Paracetamol +caudal ropivacaine
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Aga Khan University
Laparoscopic Radical Gastrectomy, Enhanced Recovery After Surgery
Patients Undergoing Laparoscopic Radical Gastrectomy Walk Out From Operating Room After Surgery ( WOFOR-G-01 )
Although early and progressive mobility is widely accepted as an important aspect of postoperative care, guidelines and recommendations suggesting the exact timing and intensity of mobilization efforts are nonexistent.
- Trial name
- NCT04029753
- Testing
- Walk out from operating room
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Morbid Obesity Requiring Bariatric Surgery, Postoperative Pain
Effect of Lidocaine-Dexmedetomidine on Pain, Inflammation, and Oxidative Stress After Bariatric Surgery.
The goal of this randomized clinical trial is to find out whether giving an intravenous lidocaine + dexmedetomidine combination (LIDEX) during laparoscopic bariatric surgery can lower post-operative pain, inflammation, and…
- Conditions
- Morbid Obesity Requiring Bariatric Surgery, Postoperative Pain, Postoperative Pain Management, Postoperative Analgesia
- Trial name
- NCT07073846
- Testing
- Intravenous Lidocaine infusion + Standard Anesthesia, Intravenous Dexmedetomidine infusion + Standard Anesthesia, Lidocaine + Dexmedetomidine Combination (LIDEX) + Standard Anesthesia
- Where
- 2 sites in Mexico
- Volunteers
- 104 people
- Sponsor
- Instituto Mexicano del Seguro Social
Transfer Anxiety, Intensive Care Unit Discharge
Nurse-Led Transfer Program With Family Involvement to Reduce ICU Patient Anxiety
This study aims to evaluate whether including a patient's family member during transfer from the intensive care unit (ICU) to the general ward can help reduce anxiety in patients who have undergone cardiovascular surgery.
- Conditions
- Transfer Anxiety, Intensive Care Unit Discharge, Cardiac Surgery Recovery, Postoperative Anxiety
- Trial name
- FICARE-TX (NCT06979414)
- Testing
- Nurse-led Transfer Programme with Family Involvement
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Yakup Akyüz
Analgesics, Opioid
Benefits of Opioid Free Anesthesia on Morphine Consumption in Gastric Bypass
Opioid free anesthesia is a recent anesthesia technique with the aim to avoid peroperative use of morphinics to allow a diminution of secondary morphinics effects in the postoperative period.
- Trial name
- NCT05004519
- Testing
- Dexmedetomidine Injection [Precedex], Remifentanil
- Where
- Belgium
- Volunteers
- 183 people
- Sponsor
- matthieu clanet
Uterus Disease
Impact of a Minimally Invasive Approach to Laparoscopic Hysterectomy on Postoperative Recovery
Background Managing perioperative stress, including endocrino-metabolic changes and, inflammatory and pain responses, is a major challenge to improve patient's recovery.
- Trial name
- MIN-HYSTER (NCT05102032)
- Testing
- mini invasive approach, Conventional approach
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Institut Mutualiste Montsouris
Enhanced Recovery After Surgery, Cesarean Section
The Effect of Enhanced Recovery After Surgery (ERAS) for Cesarean Section on Neonatal Blood Glucose
Enhanced Recovery After Surgery (ERAS) is a set of evidence-based guidelines that may be used during perioperative care for cesarean section.
- Trial name
- NCT05081804
- Testing
- Carbohydrate Preoperative Drink
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Uncontrolled Postoperative Pain
Can Post-operative TAP Block Improve Quality of Recovery After C-sections in Patients on Methadone Maintenance?
This is a prospective randomized double-blind placebo controlled study (0.375% Ropivacaine vs. 0.9% saline) designed to evaluate the effectiveness of transverse abdominis plane (TAP) block in the first 48 hours after c-section in…
- Trial name
- TAP (NCT01644864)
- Testing
- 0.375% ROPIVACAINE
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Perineal Injury, Pain Vulva
Improving Postoperative Recovery: A Study of Multimodal Perineal Analgesia Protocol (MPAP) After Vaginal Surgery
The purpose of this research is to determine if using perineal ice packs, medicated witch-hazel pads (MAJOR® Medi-Pads), and topical benzocaine spray (Dermoplast®) helps reduce perineal pain after perineorrhaphy and/or posterior…
- Conditions
- Perineal Injury, Pain Vulva, Perineum; Injury
- Trial name
- NCT07401134
- Testing
- Perineal ice packs, medicated witch-hazel pads, and topical benzocaine spray
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Miami
Colorectal Cancer
Enhanced Recovery After Surgery in Patients Undergoing Colorectal Cancer Surgery
This study compared an Enhanced Recovery After Surgery (ERAS) care program with conventional perioperative care in adults undergoing surgery for colorectal cancer. Participants received either ERAS care or usual care.
- Trial name
- NCT07889934
- Testing
- Enhanced Recovery After Surgery (ERAS) Pathway, Conventional Perioperative Care
- Where
- Greece
- Volunteers
- 91 people
- Sponsor
- University of West Attica
Postoperative Pain
Evaluation of Postoperative Quality of Recovery Score in Radical Prostatectomy With Erector Spinae Plane Block
Radical prostatectomy is performed with a median incision below the umbilicus. Although the position is supine, the waist extension movement is created in order to facilitate access to the surgical site.
- Trial name
- NCT05853133
- Testing
- Erector Spinae Plane Block, Wound Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Eskisehir Osmangazi University
Total Knee Arthroplasty
Adductor Canal Block With or Without Biceps Femoris Short Head Block in Total Knee Arthroplasty
Total knee arthroplasty is associated with moderate to severe postoperative pain, which may delay mobilization and recovery. Multimodal analgesia including regional anesthesia techniques is widely used to improve outcomes.
- Trial name
- NCT07568106
- Testing
- Adductor Canal Block, Biceps Femoris Short Head Block
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Cukurova University
Delirium
Clinical Investigation of an Eye-Tracking Device as a Predictor of Delirium in the Recovery Room After Surgery With General Anesthesia
Neurotrack™ is an FDA-approved device for measuring and tracking cognitive decline, as may occur with age-related cognitive decline and Alzheimer's disease.
- Trial name
- NCT05579093
- Testing
- Cognitive test + Pupillary measure
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Columbia University
Breast Cancer, Shoulder Dysfunction
Exercise Prehabilitation of Breast Cancer
This prospective prehabilitation trial evaluated the effectiveness of an individualized exercise program initiated before breast cancer surgery and maintained for 12 months.
- Conditions
- Breast Cancer, Shoulder Dysfunction, Quality of Life, Postoperative Recovery
- Trial name
- Prehab of BC (NCT07240584)
- Testing
- Exercise-Based Prehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Quality of Recovery, Perioperative Complication
Validation of the QoR-15 Score for Emergency Surgery
Recovery from surgery is a complex process, depending on the characteristics of the patient, the anesthesia used, and the time required for surgical management.
- Conditions
- Quality of Recovery, Perioperative Complication, Anesthesia, Patient Reported Outcome Measures
- Trial name
- FQoR-15U (NCT04845763)
- Testing
- FQoR-15 questionnaire
- Volunteers
- 375 people
- Sponsor
- University Hospital, Angers
Postoperative Pain
A Comparison of Intra-op Ketamine vs Placebo in Patients Having Spinal Fusion
Postoperative pain is severe after major spine surgery. Opioids such as morphine and hydromorphone are routinely used for postoperative pain control.
- Trial name
- NCT02424591
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- NYU Langone Health
Postoperative Pain, Recovery
Methadone for Enhanced Postoperative Analgesia in Intermediate-Risk Noncardiac Surgery (MELODY)
Postoperative pain control remains suboptimal for a large proportion of surgical patients and is frequently associated with slower recovery and higher reliance on opioids after surgery.
- Trial name
- MELODY (NCT07565870)
- Testing
- Intravenous Methadone, Short-acting Opioids Intraoperative analgesia
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Alexandre P. Joosten
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