Clinical trials: Rectal Bleeding
Colorectal Cancer, Precancerous Polyp
A Study of a Urine Test to Detect Colorectal Cancer
The purpose of this study is to find out whether a urine test can detect colorectal cancer (CRC) and precancerous polyps in participants living in Ghana, Tanzania, and South Africa.
- Conditions
- Colorectal Cancer, Precancerous Polyp, Rectal Bleeding, CRC
- Trial name
- NCT07649057
- Testing
- 3-metabolite biosensor
- Where
- 4 sites in United States, Ghana and 2 more
- Volunteers
- 210 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Bleeding Hemorrhoids, Rectal Evacuation Disorders
Rectal Evacuation Disorders and Straining-associated Symptoms in Bleeding Hemorrhoids
This study aims to understand the mechanisms of straining on anorectal testing, to better help people receive more effective treatment advice.
- Trial name
- NCT07161765
- Testing
- Anorectal manometry
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Haemorrhoid, Haemorrhoidal Bleeding
Hemorrhoid Suture Mucopexy Combined With Laser Hemorrhoidoplasty
This prospective cohort study evaluates whether combining "suture mucopexy" (a simple stitch-based lift of prolapsed tissue) with Laser Hemorrhoidoplasty (LHP) can effectively relieve pain, bleeding and prolapse in adults with…
- Conditions
- Haemorrhoid, Haemorrhoidal Bleeding, Anorectal Surgeries, Anorectal Diseases
- Trial name
- HeMuLa (NCT07404774)
- Testing
- Laser Haemorrhoidoplasty and Suture Mucopexy
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Isolated Rectal Bleedings
Isolated Rectal Bleeding in Newborns : Allergic Proctocolitis or Neonatal Colitis Transient - COLON Study
Prospective observational pilot study evaluating the frequency of cow's milk protein allergic prococolitis in newborns hospitalized in neontal medicine at the university hospital of Nice who presented rectal bleeding.
- Trial name
- COLON (NCT06088537)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Colon Cancer, Upper Rectum Cancer
Informativeness to Digital Rectal Examination
Digital rectal examination is an act clinically performed daily by physicians and surgeons. It remains the key diagnostic test and directs the therapeutic management of cancer of the lower and middle rectum.
- Conditions
- Colon Cancer, Upper Rectum Cancer, Diverticulitis, Rectal Bleeding
- Trial name
- RIFIONA (NCT01727388)
- Testing
- lateral decubitus, supine decubitus
- Where
- 2 sites in France
- Volunteers
- 320 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Bowel Cancer, Bowel Diseases, Inflammatory
LuCID - Investigating the Use of a Novel Digital Rectoscope for Community Examinations During COVID-19
The LumenEye scope and CHiP platform will be piloted in a number of clinical settings including remote colorectal clinics. The rationale is to perform an initial pilot study to determine the clinical utility of the LumenEye…
- Conditions
- Bowel Cancer, Bowel Diseases, Inflammatory, Rectal Bleeding
- Trial name
- LuCID (NCT05043363)
- Testing
- LumenEye X1 digital rectoscope
- Where
- United Kingdom
- Volunteers
- 114 people
- Sponsor
- Imperial College London
Thrombosis, Venous, Colo-rectal Cancer
Recurrence and Bleeding in Colorectal Cancer Patients With Cancer-associated Venous Thrombembolism
Patients with colorectal cancer (CRC) have a higher risk of both venous thromboembolism (VTE) and major bleeding (MB). Patients with CRC are underrepresented in the major trials examining treatment of cancer-associated VTE with…
- Conditions
- Thrombosis, Venous, Colo-rectal Cancer, Bleeding
- Trial name
- NCT06440044
- Testing
- Data collection
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Peritoneal Metastases, Peritoneal Carcinomatosis
Changes in Coagulation in Colorectal Cancer Patients Undergoing Surgical Treatment
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) has prolonged the survival substantially for selected patients with peritoneal metastases from colorectal cancer.Bleeding and thromboembolic disease…
- Conditions
- Peritoneal Metastases, Peritoneal Carcinomatosis, Colorectal Neoplasms Malignant, Intestinal Neoplasms
- Trial name
- CONTEST (NCT04744688)
- Where
- 2 sites in Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Chronic Radiation Proctitis, Rectal Bleeding
Transverse Colostomy for Refractory Hemorrhagic Chronic Radiation Proctitis: a Prospective Cohort Study
Refractory rectal bleeding of chronic radiation proctitis (CRP) is still problematic and does not respond to medical treatments including reagents, endoscopic argon plasma coagulation (APC) or topical formalin.
- Conditions
- Chronic Radiation Proctitis, Rectal Bleeding, Colostomy Stoma, Anemia
- Trial name
- NCT03397901
- Testing
- Transverse colostomy
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Rectal Bleeding
Diagnostic Outcomes of Patients Presenting With Per Rectal Bleed in Surgical Departments of Services Hospital Lahore
It is a cross sectional study in which investigators will be recruiting patients of any sex above 12 years of age who will present to surgical outdoor with per rectal bleed.
- Trial name
- NCT03594942
- Testing
- procto sigmoidoscopy and biopsy if required
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Services Hospital, Lahore
Rectal Bleeding
Colonic Capsule Endoscopy (CCE) for Screening of Neoplasm's A Pilot Study
The primary aim is to evaluate the efficiency of capsule endoscopy (CCE) in in the detection of neoplasms compared to conventional colonoscopy in persons participating in the Danish screening program for colorectal cancer with a…
- Trial name
- NCT02303756
- Testing
- Pillcam® COLON Capsule
- Where
- Denmark
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Colorectal Cancer, Rectal Bleeding
Desmopressin (DDAVP) in Patients With Colorectal Cancer and Rectal Bleeding
The objective of this study is to find the maximum tolerated dose and preliminary efficacy of desmopressin as an haemostatic agent, when is administered to patients with colorectal cancer and rectal bleeding, before specific…
- Trial name
- NCT01623206
- Testing
- Desmopressin
- Where
- 2 sites in Argentina
- Volunteers
- 30 people
- Sponsor
- Laboratorio Elea Phoenix S.A.
Radiation Injuries, Telangiectasis
Comparison Between Two Different Parameters of Argon Plasma Coagulation in the Treatment of Chronic Radiation Proctitis: Historical Control Trial.
There is a wide variability of options for treatment of chronic radiation proctitis. However, studies are still limited, usually case reports from a single center and few are comparative studies between methods.
- Conditions
- Radiation Injuries, Telangiectasis, Rectal Bleeding
- Trial name
- NCT02104271
- Testing
- Argon Plasma Coagulation, Historical control
- Where
- Brazil
- Volunteers
- 41 people
- Sponsor
- Barretos Cancer Hospital
Rectal Bleeding
Trial of Argon Plasma Coagulation Versus APC and APC and Hemospray in the Treatment of Radiation Proctitis
Randomized trial of Argon Plasma Coagulation compared with Argon Plasma Coagulation and Hemospray in the therapy of bleeding from Radiation Proctitis
- Trial name
- NCT02233933
- Testing
- Hemospray
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- British Columbia Cancer Agency