Clinical trials: Rectal Cancer, completed
Small Bowel Cancers, Colorectal Cancers
Phase II Trial of Combination Immunotherapy in Subjects With Advanced Small Bowel and Colorectal Cancers
Background: Metastatic or refractory/recurrent small bowel and colorectal cancers cannot be cured and are often not helped by standard treatments. Researchers want to find better treatments by testing a combination of drugs.
- Trial name
- NCT04491955
- Testing
- CV301, MSB0011359C, N-803
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer
A Study of Avastin (Bevacizumab) in Combination With XELOX or FOLFOX-4 in Patients With Metastatic Colorectal Cancer.
This 2 arm study will compare the pharmacokinetics and safety of Avastin at steady state under 2 different dosing regimens, in combination with XELOX (oxaliplatin + Xeloda) or FOLFOX-4 (oxaliplatin, leucovorin and…
- Trial name
- NCT00349336
- Testing
- bevacizumab [Avastin], XELOX, FOLFOX-4
- Where
- 7 sites in Australia, Canada and 1 more
- Volunteers
- 64 people
- Sponsor
- Hoffmann-La Roche
Colorectal Cancer, Psycho-Oncology
The Effects of Nurse Navigation Program on Symptom Management and Psychosocial Adjustment in Colorectal Cancer Patients
This study was conducted to examine the effect of the nurse navigation program (NNP) applied to patients with colorectal cancer on symptom management and psychosocial adjustment to the disease.
- Conditions
- Colorectal Cancer, Psycho-Oncology, Nursing
- Trial name
- NCT05571098
- Testing
- individualized colorectal cancer education, psycho-oncological counseling, telephone support hotline service
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
Colorectal Cancer
RAD001, FOLFOX and Bevacizumab in Treatment of Colorectal Carcinoma
RAD001 (everolimus) is a novel oral derivative of rapamycin. RAD001 has been in clinical development since 1996 as an immunosuppressant in solid organ transplantation and has obtained marketing authorization (Certican®) for…
- Trial name
- NCT01047293
- Testing
- RAD001, FOLFOX, Bevacizumab
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- University of Utah
Colorectal Cancer, Adenoma
Care for Colon 2015
The investigatior believe that implementing camera capsule endoscopy as a filter test to colonoscopy will increase screening participation, increase the number of individuals with detected intermediate- high risk adenomas or…
- Trial name
- CFC2015 (NCT04049357)
- Testing
- Camera Capsule Endoscopy/ PillCam
- Where
- Denmark
- Volunteers
- 2,031 people
- Sponsor
- Odense University Hospital
Metastatic Colorectal Cancer
Escalated Dose of Irinotecan in mCRC
Metastatic diseases were found in 20-25% of patients with initial diagnosis of colorectal cancer and developed in up to 50% of patients.
- Trial name
- NCT02256800
- Testing
- UGT1A1 genotyping (6,6), UGTIA1 genotyping (6,7), UGTIA1 genotyping (7,7)
- Where
- Taiwan
- Volunteers
- 213 people
- Sponsor
- Jaw-Yuan Wang, MD, PhD
Metastatic Colorectal Cancer
Panitumumab in Combination With Irinotecan Chemotherapy as 2nd-line Therapy in Subjects With mCRC
The purpose of this study is to assess the objective response rate (ORR) when panitumumab is administered in combination with irinotecan as 2nd-line therapy in subjects with previously treated metastatic colorectal cancer (mCRC).
- Trial name
- NCT00475293
- Testing
- Panitumumab and CPT-11
- Where
- Spain
- Volunteers
- 85 people
- Sponsor
- Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)
Colorectal Cancer, Metastatic Cancer
Evaluating Panitumumab (ABX-EGF) Monotherapy in Patients With Metastatic Colorectal Cancer Following Treatment With Fluoropyrimidine, Irinotecan, and Oxaliplatin Chemotherapy
The purpose of this study is to determine that panitumumab will have clinically meaningful anti-tumor activity in patients with metastatic colorectal cancer who have developed progressive disease or relapsed while on or after…
- Trial name
- NCT00083616
- Testing
- Panitumumab
- Volunteers
- 185 people
- Sponsor
- Amgen
Rectum Cancer
Rectal Study: Value of Repeated FDG-PET-CT Scans in Rectal Cancer
To investigate the evolution of the 18F-deoxyglucose (FDG) uptake and the tumour characteristics determined in the plasma of patients with rectal cancer during and after radiotherapy or combined radiotherapy and chemotherapy.
- Trial name
- NCT00576563
- Testing
- FDG
- Where
- Netherlands
- Volunteers
- 103 people
- Sponsor
- Maastricht Radiation Oncology
Colon Cancer, Primary Tumour
The Role of Surgery of the Primary Tumour in Patients With Synchronous Unresectable Metastases of Colorectal Cancer
The clinical benefit of resection of the primary tumour in patients with synchronous unresectable metastases is not known. In the literature studies usually describe retrospective selected patients with synchronous metastases…
- Conditions
- Colon Cancer, Primary Tumour, Rectal Cancer
- Trial name
- CAIRO4 (NCT01606098)
- Testing
- Surgery of the primary tumour, Systemic treatment
- Where
- 46 sites in Denmark, Netherlands
- Volunteers
- 206 people
- Sponsor
- Dutch Colorectal Cancer Group
Low Anterior Resection Syndrome, Quality of Life (QOL)
Bowel Dysfunction After Low Rectal Resection. An Pilot Study Using Psyllium Husk In Rectal Cancer Patients.
Rectal cancer constitutes 1/3 of more than 4500 annually diagnosed cases of colorectal (CRC) in Norway. With the advances in radiochemotherapy, and surgical techniques, the long-term survival rate is increasing after surgery…
- Trial name
- NCT06724198
- Testing
- Psyllium husk
- Where
- Norway
- Volunteers
- 24 people
- Sponsor
- Sykehuset Telemark
Colorectal Cancer
The Microbrect-FFC Study
This study will focus on two points: 1. To determine if response to neoadjuvant chemoradiotherapy treatment in rectal cancer can be predicted by analysing data from Fast Field Cycling imaging (FFC), a novel type of MRI technique.
- Trial name
- NCT06236321
- Testing
- Fast Field Cycling MRI scan, Provision of saliva and faecal samples
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Aberdeen
Stomach Cancer, Pancreatobiliary Cancer
Effects of Red Ginseng on Gastrointestinal Symptoms and Microbiota After Surgery for Gastrointestinal Cancer
After surgery for gastrointestinal cancer (stomach cancer, pancreaticobiliary cancer, colorectal cancer), many patients experiences various symptoms such as weight loss, diarrhea, constipation and excessive gas due to structural…
- Conditions
- Stomach Cancer, Pancreatobiliary Cancer, Colorectal Cancer
- Trial name
- NCT06561516
- Testing
- Arm I (Red ginseng)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Gangnam Severance Hospital
Colon Cancer, Pancreatic Cancer
Negative Pressure Therapy in Preventing Infection After Surgery in Patients With Colon, Rectal, Pancreatic, or Peritoneal Surface Cancer
The purpose of this research study is to evaluate if a negative-pressure dressing placed over a surgical incision can reduce the risk of developing a surgical site infection compared to a commonly-used sterile gauze incision…
- Conditions
- Colon Cancer, Pancreatic Cancer, Perioperative/Postoperative Complications, Primary Peritoneal Cavity Cancer
- Trial name
- NCT01656044
- Testing
- wound care management
- Where
- United States
- Volunteers
- 375 people
- Sponsor
- Wake Forest University Health Sciences
Rectal Cancer, Cancer of the Rectum
5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer
This phase II trial will investigate the combination of adjuvant 5-fluorouracil, radiation, and bevacizumab in patients with stage II and III rectal cancer, followed by FOLFOX6 and bevacizumab.
- Conditions
- Rectal Cancer, Cancer of the Rectum, Colorectal Cancer
- Trial name
- NCT00308516
- Testing
- 5-Fluorouracil, Bevacizumab, Radiation Therapy
- Where
- 14 sites in United States
- Volunteers
- 66 people
- Sponsor
- SCRI Development Innovations, LLC
Colorectal Cancer
Community Collaboration to Advance Racial/Ethnic Equity in CRC Screening
The goal of this pragmatic randomized clinical trial is to compare two colorectal (CRC) screening outreach approaches (FIT and Cologuard) in community health centers (CHC) in patients overdue for CRC screening.
- Trial name
- CARES (NCT05714644)
- Testing
- FIT kit Screening Test, Cologuard Screening Test
- Where
- 3 sites in United States
- Volunteers
- 5,127 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Colorectal Cancer
Capecitabine and Irinotecan in Treating Patients With Locally Advanced, Recurrent, or Metastatic Colorectal Cancer
PURPOSE: Phase II trial to study the effectiveness of combining capecitabine and irinotecan in treating patients who have locally advanced, recurrent, or metastatic colorectal cancer.
- Trial name
- NCT00022698
- Testing
- Capecitabine, Irinotecan
- Where
- 17 sites in United States
- Volunteers
- 67 people
- Sponsor
- Hoffmann-La Roche
Colorectal Cancer
Barriers to Care in Patients With Rectal Bleeding in Nigeria
This study sought to find the health seeking behavior of patients with rectal bleeding as related to their risk to develop colorectal cancer and also assess the general practitioner's perceived barriers to colonoscopy for…
- Trial name
- NCT02855385
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University Teaching Hospital
Sarcopenia, Colon Cancer
Preoperative Sarcopenia and Surgical Outcomes in Colorectal Cancer Patients
Colorectal cancer is the third most common malignant neoplasm worldwide and the fourth leading cause of cancer-related deaths. Muscle mass loss in oncology patients is most often the result of cancer-related malnutrition.
- Conditions
- Sarcopenia, Colon Cancer, Rectal Cancer, Surgical Outcomes
- Trial name
- NCT06698289
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Mersin University
Radiation-induced Diarrhoea in Prostate and Rectal Cancer
Radiation-induced Diarrhoea During Curative EBRT of Prostate and Rectal Cancer
Approx. 80% of patients with prostate and rectal cancer who receive radiation therapy (RT) experience acute radiation-induced diarrhea (RID).
- Trial name
- PRECANU (NCT05684432)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aalborg University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.