Clinical trials: Rectal Cancer Patients
Colorectal Cancer
Assessing the Effect of a Blood-based Colorectal Cancer Screening Test on Screening Adherence and Colonoscopy Completion
Objectives: Colonoscopy and stool-based testing are the two predominant colorectal cancer (CRC) screening tests used in the US, and both reduce colorectal cancer mortality.
- Trial name
- NCT03598166
- Testing
- Septin9
- Where
- United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- Peter S. Liang, MD MPH
Colorectal Cancer
Risk Stratification to Promote Effective Shared Decision-Making for Colorectal Cancer Screening
Shared decision-making (SDM) has been advocated as a strategy for increasing colorectal cancer (CRC) screening rates. Our studies to date suggest that while the use of a novel computer-based decision aid facilitates several…
- Trial name
- NCT01596582
- Testing
- Risk Assessment
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Rectal Cancer
Neoadjuvant Chemoradiation With RHUMAB VEGF (Avastin) for Rectal Cancer
Preoperative chemoradiation leads to increased pelvic control and overall survival, but both distant and local disease control remain problematic in locally advanced rectal cancer patients.
- Trial name
- NCT00113230
- Testing
- Avastin (Bevacizumab, RHUMAB VEGF), Capecitabine, Radiation Therapy
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Cancer
Colonoscopy Outreach for Rural Communities Aim 2
This study aims to test the effectiveness of a remotely-delivered patient navigation program for increasing colonoscopy completion for colorectal cancer screening, among rural populations.
- Trial name
- NCT05453630
- Testing
- Patient Navigation, Usual Care Control
- Where
- United States
- Volunteers
- 527 people, healthy volunteers welcome
- Sponsor
- University of Washington
Health Behavior, Colorectal Cancer
Building Engagement Using Financial Incentives Trial - Colorectal Cancer Screening
The goal of this pilot clinical trial is to determine feasibility and explore whether financial incentives paid to primary care patients for completing colorectal cancer screening increase completion of colorectal cancer…
- Conditions
- Health Behavior, Colorectal Cancer, Influenza, COVID-19
- Trial name
- BENEFIT-C (NCT06124131)
- Testing
- Financial incentive for colorectal cancer screening, Financial incentive for flu shot, Financial incentive for COVID-19 shot
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tulane University
Colorectal Neoplasms
Evaluating a Preference-based Intervention for Increasing Colorectal Cancer Screening
The goal of this study is to evaluate whether an educational tool about colorectal cancer (CRC) completed on a computer that helps patients clarify their CRC screening preferences will lead to increased screening rates for CRC…
- Trial name
- EPIIC (NCT00810771)
- Testing
- Standard Information, Preference-tailored Information
- Where
- 2 sites in United States
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Colorectal Cancer
Scaling CRC Screening Through Outreach, Referral, and Engagement (SCORE)
This study will test the effectiveness of mailing fecal immunochemical tests (FITs) in increasing colorectal cancer (CRC) screening rates in U.S. adults ages 45-75.
- Trial name
- SCORE (NCT04406714)
- Testing
- Trial Mailed FIT Intervention - Age Group 50-75, Sub-Study Mailed FIT Intervention Enhanced Envelope - Age Group 45-49, Sub-Study Mailed FIT Active Comparator Plain Envelope - Age Group 45-49
- Where
- 2 sites in United States
- Volunteers
- 4,318 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Colorectal Cancer
Polyp Measurement Device
Colorectal cancer is the second-leading cause of cancer death in the United States. Colorectal cancer screening is recommended to begin at age 50 years for most men and women at average risk for this disease.
- Trial name
- NCT03856255
- Testing
- Micro-Tech Endoscopic Gauge
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Acute Myelogenous Leukemia, Ovarian Cancer
Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced Cancers
To evaluate the safety, tolerability, and anti-tumor activity of galinpepimut-S in combination with pembrolizumab in patients with selected advanced cancers.
- Conditions
- Acute Myelogenous Leukemia, Ovarian Cancer, Colorectal Cancer, Triple-negative Breast Cancer
- Trial name
- NCT03761914
- Testing
- galinpepimut-S, pembrolizumab, Montanide
- Where
- 12 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Sellas Life Sciences Group
Colorectal Cancer
Comparing Interventions to Increase Colorectal Cancer Screening
The purpose of this study is to test different approaches to help people understand the purpose of colorectal cancer (CRC) screening, two screening test options available, and the barriers to screening so they can make informed…
- Trial name
- NCT03200366
- Testing
- Tailored DVD, Patient Navigation
- Where
- 2 sites in United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colorectal Cancer
Efficacy and Patient Satisfaction of Miralax and Gatorade Versus Movi Prep
This study will be comparing patient satisfaction, efficacy comparing miralax with gatorade versus Movi Prep for outpatient colonoscopy.
- Trial name
- NCT01695863
- Testing
- comparing 2 drugs on their effect on the bowel preparation for colonoscopy
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Colo-rectal Cancer
A Patient-centered Intervention Using Technology to Reduce Colorectal Cancer Disparities in Primary Care
The purpose of this proposal is to test the efficacy of a patient-centered, tailored message intervention delivered via virtual technology for increasing colorectal cancer (CRC) screening within guidelines among racial/ethnic…
- Trial name
- NCT03407417
- Testing
- virtual technology
- Where
- 2 sites in United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Florida
Colorectal Cancer
Low-Literacy Physician-Patient Intervention Promoting Colorectal Cancer Screening
The purpose of this study is to evaluate the effectiveness of a low literacy, physician and patient-directed intervention to promote colorectal cancer (CRC) screening among the medically underserved.
- Trial name
- NCT01103479
- Testing
- Physician Intervention, Physician and Patient Intervention
- Where
- 2 sites in United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Colorectal Carcinoma
Screening More Patients for Colorectal Cancer Through Adapting and Refining Targeted Evidence-Based Interventions in Rural Settings, SMARTER CRC
This study collects information to provide a model for how to rapidly adapt and scale-up multilevel interventions through clinic-health plan partnerships to reduce the burden of colorectal cancer (CRC) on the United states…
- Trial name
- SMARTER CRC (NCT04890054)
- Testing
- Fecal Immunochemical Test, Interview, Patient Navigation
- Where
- United States
- Volunteers
- 5,696 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Colorectal Cancer
Increasing Colorectal Cancer (CRC) Screening Among Hispanic Primary Care Patients
This study is designed to test a standard mailed intervention (SI) versus a novel decision support and navigation intervention (DSNI).
- Trial name
- NCT02272244
- Testing
- Decision Support & Navigation, Standard
- Where
- 3 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University