Clinical trials: Rectal Fistula
Anal Fistula
Imaging Template for Reporting Anal Fistula
Magnetic resonance imaging (MRI) is the most used diagnostic tool for pre-operative assessment of anal fistula. However, there is lack of standardization in reporting this investigation.
- Trial name
- ITRAF (NCT04541238)
- Testing
- MRI
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Treviso Regional Hospital
Quality of Recovery
Comparison of Propofol and Sevoflurane Anesthesia on the Quality of Recovery After Ambulatory Surgery in Obese Patients
This study was designed to compare propofol intravenous anesthesia to sevoflurane inhalation anesthesia on the quality of recovery after surgery for anal fistula in obese patients.
- Trial name
- NCT05529875
- Testing
- Propofol, sevoflurane
- Where
- China
- Sponsor
- Jiangang Song
Perianal Fistula, Fissure in Ano
Perianal Nerval Block in Proctological Interventions
The aim of this study is to evaluate whether a local perianal block performed during a proctological intervention can reduce the postoperative pain.
- Conditions
- Perianal Fistula, Fissure in Ano, Hemorrhoids
- Trial name
- NCT03405922
- Testing
- 40 mL Ropivacain 0.5%
- Where
- Switzerland
- Volunteers
- 166 people
- Sponsor
- University Hospital, Basel, Switzerland
Kegel Exercises
Effect of Anal Lift Exercise on Rehabilitation After Anal Fistula Surgery
This prospective randomized controlled study aims to include patients who have undergone anal fistula surgery, to observe the impact of early postoperative pelvic floor muscle training combined with dietary intervention on…
- Trial name
- NCT07250711
- Testing
- Kegel exercises
- Where
- China
- Volunteers
- 124 people
- Sponsor
- The Affiliated Hospital of Putian University
Anal Fistula, Anal Abscess
Oral Antibiotics for Anal Abscess
BACKGROUND Anal abscess and perianal fistula is a high prevalence disorder in general population that affect adult patients on young ages, affecting them significantly their social and quality of life.
- Trial name
- OFF (NCT03643198)
- Testing
- ANTIBIOTIC (METRONIDAZOLE AND CIPROFLOXACIN), CONTROL
- Where
- Spain
- Volunteers
- 210 people
- Sponsor
- Germans Trias i Pujol Hospital
Fistula in Ano
Compound Phellodendron Decoction May Promote Wound Healing After Anal Fistulotomy
Sitz-bath therapy with Chinese medicine has significant advantages in the management of postoperative wounds of anal fistula. This method not only ensures safety, efficacy, and cost-effectiveness, but also simplifies application.
- Trial name
- CPD (NCT06663527)
- Testing
- Fumigating-washing Therapy With CPD
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Anal Fistula
"Feasibility and Safety of the Calcium Alginate Hydrogel Sealant for the Treatment of Cryptoglandular Fistula-in-ano: Phase I/IIa Clinical Trial"
Background: Complex perianal fistulas pose a challenge to surgeons since the fistulous tract must be eliminated without impairing continence.
- Trial name
- NCT04740086
- Testing
- Calcium alginate hydrogel
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Anorectal Fistula
Retrospective Review of the Cook Biodesign® Fistula Plug to Treat Anorectal Fistulas
The study is a retrospective review of the use of the Biodesign® Fistula Plug (C-FPS-[X]). A total of 73 patients will be enrolled who have had a fistula plug placed to treat anorectal fistulas and will therefore be eligible for…
- Trial name
- NCT03321266
- Testing
- Cook Biodesign® Fistula Plug
- Where
- 4 sites in United States, Germany
- Volunteers
- 79 people
- Sponsor
- Cook Group Incorporated
Anorectal Fistula
Anal Sphincter Reconstruction After High Recurrent Anorectal Fistula Excision
A retrospective analysis of patients treated for recurrent posterior anorectal fistula, who previously had undergone radical excision of fistula-in-ano, was performed.
- Trial name
- NCT04357210
- Testing
- fistula tract excision and anal sphincter reconstruction
- Volunteers
- 14 people
- Sponsor
- Russian Society of Colorectal Surgeons
Perianal Crohn Disease, Perianal Fistula
The Impact of Perianal Disease on Patient's Sex Life
Perianal diseases, such as perianal abcesses, anal fistulae and perianal Crohn's disease, are often associated with significant physical symptoms, including pain and chronic drainage.
- Conditions
- Perianal Crohn Disease, Perianal Fistula, Fistula in Ano, Perianal Abscess
- Trial name
- SEXTON (NCT07519850)
- Testing
- Patient Reported Outcome Assessment (Questionnaires)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- AHEPA University Hospital
Fistula in Ano
Role of Udumbara Sutra in the Management of Fistula in Ano a Rare Case Study
The anal fistula is a notorious disease due to its recurrence rate. Bhagandara is varyingly defined as a tear, ulcer or boil at Bhaga (Perianal region) within 2 finger circumference of it, causing painful abscess when opened is…
- Trial name
- Bhagandara (NCT01954225)
- Testing
- Udumbara Sutra
- Where
- India
- Volunteers
- 1 people
- Sponsor
- Government Ayurved College and Hospital
Anorectal Fistulas
A Prospective, Multi-center, Observational Study of the Use of Permacol™ Collagen Paste to Treat Anorectal Fistulas
This will be a prospective, multi-center, post-market, single arm observational study to collect clinical outcome data on the use of Permacol™ Collagen Paste in the treatment of anorectal fistulas.
- Trial name
- NCT01624350
- Testing
- Permacol collagen paste
- Where
- 10 sites in Denmark, Italy and 1 more
- Volunteers
- 100 people
- Sponsor
- Medtronic - MITG
Anal Fistula
Endorectal Three-dimensional Ultrasound in the Diagnosis of Cryptogenic Fistulas of the Rectum.
Prospective comparative parallel ultrasound diagnostic transrectal study in the diagnosis of cryptogenic fistulas of the rectum
- Trial name
- NCT03743701
- Testing
- The method of transrectal ultrasound in В-mode, The method of transrectal ultrasound examination using three-dimensional image reconstruction.
- Where
- Russia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Anal Fistula
Treatment of Complex Anal Fistulas Using Centrifuged Adipose Tissue Containing Progenitor Cells
In the treatment of complex anal fistulas transplant of freshly collected autologous adipose tissue mechanically fragmented or centrifuged adipose tissue (CAT) might be an alternative to in vitro expanded autologous or allogeneic…
- Trial name
- CAT (NCT04326907)
- Testing
- Autologous centrifuged adipose tissue (CAT) injection after anal fistulectomy
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Anal Fistula Surgery, Anal Fistula
Impact of Surgical Timing on Anal Fistula Outcomes
This study aims to evaluate if the amount of time a person experiences symptoms of an anal fistula before having surgery affects their surgical outcomes and recovery.
- Conditions
- Anal Fistula Surgery, Anal Fistula, Surgery Timing
- Trial name
- NCT07482241
- Volunteers
- 90 people
- Sponsor
- Assiut University
Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection
Myriad™ Augmented Soft Tissue Reconstruction Registry
This is an observational study designed to evaluate the safety and clinical outcomes of Myriad™ in soft tissue reconstruction procedures.
- Conditions
- Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus
- Trial name
- MASTRR (NCT05243966)
- Testing
- Myriad Matrix™ and Myriad Morcells™
- Where
- 15 sites in United States
- Volunteers
- 800 people
- Sponsor
- Aroa Biosurgery Limited
High-type Anal Fistulae
Anal Fistula Plug for High-type Anal Fistulae
The aim of this pilot study is to evaluate the efficacy and safety of anal fistula plug in the management of high-type anal fistulae among Hong Kong Chinese patients.
- Trial name
- NCT00487071
- Testing
- Anal fistula plug
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Chinese University of Hong Kong
Perianal Fistula, Anal Fistula
Laser Ablation Versus Conventional Fistulectomy for Uncomplicated Perianal Fistula
This randomized controlled trial aims to compare conventional open fistulectomy and laser ablation in the treatment of uncomplicated perianal fistula.
- Trial name
- NCT07681531
- Testing
- Laser ablation, Conventional Open Fistulectomy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- PNS Hafeez - Naval Hospital
Hemorrhoids, Anal Fistula
Hemostatic and Analgesic Effect of Gel Foam and Gauze With Bosmin After Anal Surgery
To evaluate the hemostatic and analgesic effect of using gauze with Bosmin or Gelfoam after anal surgery.
- Trial name
- NCT05605080
- Testing
- Gelfoam, Bosmin gauze
- Where
- Taiwan
- Volunteers
- 292 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Fistula in Ano, Crohn Disease
Autologous Stem Cells in the Management of Fistulating Perianal Crohn's Disease
Crohn's disease is a chronic inflammatory condition that can affect any part of the bowel which can be controlled by a combination of medical and surgical treatments but cannot be cured.
- Trial name
- NCT06822686
- Testing
- Harvest and injection of stem cells
- Sponsor
- Oxford University Hospitals NHS Trust