Clinical trials: Rectal Surgery
Visceral Obesity, Rectal Cancer
Comparison of Robotic Versus Laparoscopic Surgery for Visceral Obesity in Mid-Low Rectal Cancer: A Propensity-Matched Analysis
Our team has previously published articles providing detailed descriptions of the steps involved in both RS and LS. All surgeries adhered to the total mesorectal excision (TME) principle.
- Conditions
- Visceral Obesity, Rectal Cancer, Robotic Surgery
- Trial name
- NCT06397053
- Testing
- robotic surgery
- Where
- China
- Volunteers
- 242 people
- Sponsor
- Daorong Wang
Rectal Cancer, Gender
Gender Differences in Robotic Surgery for Rectal Cancer: a Retrospective Study
Objective: To investigate gender-based differences in outcomes following robotic surgery for rectal cancer. Methods: A retrospective study was conducted on 155 patients (82 males, 73 females) who underwent robotic surgery for…
- Conditions
- Rectal Cancer, Gender, Complication,Postoperative, Surgery-Complications
- Trial name
- NCT06391060
- Testing
- Impact of Gender on Davinci rectal surgery
- Where
- China
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Daorong Wang
Rectal Cancer, Left Colic Artery Stenosis (Diagnosis)
Robotic-Assisted or Laparoscopic Radical Resection for Rectal Cancer With or Without Left Colic Artery Preservation
Brief Summary Background The preservation of the left colic artery (LCA) during rectal cancer resection remains a topic of controversy, and there is a notable absence of robust evidence regarding the outcomes associated with LCA…
- Conditions
- Rectal Cancer, Left Colic Artery Stenosis (Diagnosis), Robotic Assisted Laparoscopic Surgery
- Trial name
- NCT06376227
- Testing
- with or without Left Colic Artery Preservation
- Where
- China
- Volunteers
- 1,164 people
- Sponsor
- Northern Jiangsu People's Hospital
Rectal Cancer Surgery
Mechanical Bowel Preparation and Oral Antibiotics Before Rectal Cancer Surgery
This study aims to demonstrate that a preoperative combination of mechanical bowel preparation and oral antibiotics, before elective laparoscopic rectal cancer surgery, is associated with a reduction of postoperative surgical…
- Trial name
- PREPACOL2 (NCT03491540)
- Testing
- Sennosides colonic preparation, Oral Gentamycin, Oral Ornidazole
- Where
- France
- Volunteers
- 414 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Colo-rectal Surgery, Anastomotic Leak Large Intestine
Comparison of Rates of Anastomotic Leak in Patients Undergoing Colo-rectal Surgery When Bowel Perfusion and Resection Margin is Deterimined by Intra-operative Infra-red Thermography or by Conventional Method
Pilot RCT with 20 patients in both test and control group. In the control group resection \& anastomosis was done using the conventional method.
- Conditions
- Colo-rectal Surgery, Anastomotic Leak Large Intestine, Anastomotic Leak Rectum
- Trial name
- NCT06180564
- Testing
- Intra-operative Infra-red thermography
- Where
- India
- Volunteers
- 43 people
- Sponsor
- Sir Ganga Ram Hospital
Rectal Cancer, Quality of Life
Quality of Life in RECTal Cancer - a Prospective Multicenter Cohort Study
Rectal cancer is a common type of cancer occuring more frequently in men but also common in women. Almost 60% of the patients survive 5-years and the treatment has been continuously developed in the last three decades.
- Conditions
- Rectal Cancer, Quality of Life, Surgery
- Trial name
- QoLiRECT (NCT01477229)
- Where
- Sweden
- Volunteers
- 1,500 people
- Sponsor
- Sahlgrenska University Hospital
Anal Fistula, Minimal Invasive Surgery
Treatment of Anal Fistulas With Obsidian RFT®
The study conducted a retrospective analysis from January 2018 to December 2022 on patients who received anal fistula closure with Obsidian RTF® at the Department of General Surgery, Medical University of Vienna.
- Conditions
- Anal Fistula, Minimal Invasive Surgery, Platelet-rich Fibrin Foam
- Trial name
- NCT06136325
- Testing
- Obsidian RFP anal fistula surgery
- Where
- Austria
- Volunteers
- 18 people
- Sponsor
- Medical University of Vienna
Pelvic Organ Prolapse, Rectocele
Multicenter Ventral Mesh Rectopexy Registry Collaborative
The goal of this multicenter observational study is to collect data prospectively of patients with pelvic organ prolapse undergoing ventral mesh rectopexy (as well as rectoceles, entero-/sigmoidoceles/ intussusception/ rectal…
- Conditions
- Pelvic Organ Prolapse, Rectocele, Enterocele, Rectal Prolapse
- Trial name
- M2R2 (NCT05918367)
- Where
- 5 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Antwerp
Obesity, Morbid, Rectal Cancer
Evaluation of Surgical Complications and DFS in Obese Rectal Cancer Patients
Obesity worsens treatment outcomes in rectal cancer patients: the local resective approach could in fact be more difficult in obese patients due to limited surgical visibility and it has also been reported that high visceral…
- Conditions
- Obesity, Morbid, Rectal Cancer, Surgery-Complications
- Trial name
- NCT06056726
- Testing
- BIB positioning
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Federico II University
Fluorescence, Indocyanine Green
Applications of Fluorescence Imaging Guided Lymph Node Dissection and Fluorescence Angiography of Inferior Mesenteric Artery Assisted Left Colic Artery Preservation
To investigate the accuracy of fluorescence angiography technique IMA classification and the impact of lymph node mapping technique on the dissection of No. 253 lymph nodes.
- Conditions
- Fluorescence, Indocyanine Green, Rectal Cancer Surgery
- Trial name
- NCT06033794
- Testing
- Fluorescence laparoscopic system
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Rectal Neoplasms, Neoplastic Cells, Circulating
Change of Circulating Tumor Cells During Laparoscopic or Transanal Endoscopic Surgery for Rectal Cancer.
The primary purpose of this study is to compare the changes of circulating tumor cells (CTCs) at different time points in rectal cancer patients undergoing laparoscopic or transanal endoscopic radical resection.
- Conditions
- Rectal Neoplasms, Neoplastic Cells, Circulating, Laparoscopic Surgery, Transanal Endoscopic Surgery
- Trial name
- NCT05109130
- Testing
- Surgical approach
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Rectal Adenocarcinoma, Rectum Neoplasm
Mechanical Bowel Preparation and Oral Antibiotics Versus Mechanical Bowel Preparation Only Prior Rectal Surgery
MOBILE2 is a randomized controlled trial comparing mechanical and oral antibiotic bowel preparation to mechanical bowel preparation only in patients undergoing anterior rectal resection with primary anastomosis.
- Conditions
- Rectal Adenocarcinoma, Rectum Neoplasm, Rectum Carcinoma, Colorectal Cancer
- Trial name
- MOBILE2 (NCT04281667)
- Testing
- Oral Antibiotics, Mechanical Bowel Preparation
- Where
- 3 sites in Finland
- Volunteers
- 604 people
- Sponsor
- Helsinki University Central Hospital
Rectal Cancer, Quality of Life
The OPERa Study: Evaluating QoL After Rectal Cancer Surgery
Advances in rectal cancer management have significantly reduced morbidity and mortality. The most commonly performed operation for rectal cancer is restorative proctectomy (RP), leaving up to 70% with long-term bowel dysfunction…
- Conditions
- Rectal Cancer, Quality of Life, Bowel Dysfunction, Sexual Dysfunction
- Trial name
- NCT04893876
- Volunteers
- 1,200 people
- Sponsor
- Jewish General Hospital
Rectal Neoplasms, Robotic Surgery
Robotic Transanal Specimen Extraction Surgery Versus Robotic Transabdominal Incision Specimen Extraction Surgery for Patients With Rectal Cancer: A Multicenter Randomized Controlled Trial
This prospective, multicenter, randomized, open-label study aims to evaluate the perioperative safety and feasibility of specimen extraction through anus regarding robotic radical excision of rectal cancer.
- Conditions
- Rectal Neoplasms, Robotic Surgery, Natural Orifice Specimen Extraction Surgery
- Trial name
- NCT05468944
- Testing
- Transanal specimen extraction robotic surgery, Transabdominal specimen extraction robotic surgery
- Where
- 12 sites in China
- Volunteers
- 556 people
- Sponsor
- Taiyuan Li
Colo-rectal Cancer, Surgery
The Impact of Physical Exercise on Sleep in Colorectal Cancer Patients During Prehabilitation Period
Main objective: To evaluate the bidirectional relationships between physical exercise and sleep parameters, as a part of multimodal prehabilitation intervention, on pre- and postoperative outcomes in surgical patients with…
- Trial name
- NCT04270500
- Testing
- Prehabilitation program
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Montreal General Hospital
Colorectal Surgery, Rectal Cancer
Early and Late Removal of the Urinary Catheter After Rectum Resection
It was aimed to investigate the need for urinary retention and recatheterization in the postoperative period by removing the urinary catheter in patients undergoing low anterior resection, in the early or late period.
- Conditions
- Colorectal Surgery, Rectal Cancer, Urinary Retention Postoperative
- Trial name
- NCT05020613
- Testing
- Procedure: Early removal group, Procedure: Late removal group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Sexual Dysfunction, Rectal Surgery
Prevalence of Sexual Dysfunction After Rectal Surgery and Patient Satisfaction of Preoperative Discussions
Sexual dysfunction after rectal surgery varies widely in the literature. Prevalence of sexual dysfunction before surgery and desire of patient to treat this condition is also not well established.
- Conditions
- Sexual Dysfunction, Rectal Surgery, Patient Satisfaction
- Trial name
- NCT05010486
- Testing
- rectal surgery
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Rectal Cancer, Surgery
Pathology Assessment of Mesorectal Fascia After TME by Laparoscopic, Open, TransAnal and Robotic Approaches (LOTARTME)
TME is the gold standard surgical treatment of rectal cancer. Specimen quality, integrity of mesorectal fascia and lymph nodes harvest are expression of radicality and good surgery.
- Trial name
- LOTARTME (NCT04949672)
- Where
- Italy
- Volunteers
- 153 people
- Sponsor
- San Giovanni Addolorata Hospital
Rectal Surgery
Is There a Link Between Anatomical Markers of Surgical Difficulty and Incapacity to Reverse Stoma After Low Rectal Cancer Surgery?
Anterior resection with total mesorectal excision (TME) is the standard procedure for mid and low rectal cancers . A colo-rectal anastomosis under peritoneal reflection is, most of the time, protected by a temporary loop stoma to…
- Trial name
- persist stomie (NCT04006600)
- Testing
- Sphincter saving proctectomy
- Where
- France
- Volunteers
- 126 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Rectal Prolapse, Defecation Disorder
Rectal Prolapse With ODS. STARR vs LVR.
The objective of the study will be to evaluate the clinical and functional outcome of patients with obstructed defecation sndrome (ODS) associated to internal rectal prolapse, treated with transanal prolassectomy (STARR) surgery…
- Conditions
- Rectal Prolapse, Defecation Disorder, Rectocele; Female, Surgery
- Trial name
- NCT04892108
- Testing
- STARR (Stapled Trans Anal Rectal Resection), LVR (Laparoscopic Ventral Rectopexy)
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University Hospital of Ferrara