Clinical trials: Recurrent Abortion
Pregnancy, Miscarriage
Aspirin, Heparin and Miscarriage
Efficacy of low dose aspirin (LDA) versus LDA plus low-molecular-weight-heparin (LMWH) in patients with a history of recurrent miscarriages.
- Trial name
- NCT01917799
- Testing
- Aspirin, Heparin
- Where
- Libya
- Volunteers
- 150 people
- Sponsor
- University of Khartoum
Recurrent Pregnancy Loss(RPL), Anxiety
High-Intensity, Low-Frequency Periodic rTMS Over the Right Dorsolateral Prefrontal Cortex on Cardiac Autonomic Regulation in Women With Recurrent Pregnancy Loss and Anxiety
The goal of this clinical trial is to determine whether high-intensity, low-frequency periodic repetitive transcranial magnetic stimulation (rTMS) applied to the right dorsolateral prefrontal cortex (DLPFC) can modulate cardiac…
- Trial name
- NCT07233278
- Testing
- Rhythmic repetitive transcranial magnetic stimulation (rTMS) at 120% RMT, 1 Hz, 60-s cycles
- Where
- 3 sites in China
- Volunteers
- 48 people
- Sponsor
- Shenyang Medical College
Abortion, Spontaneous, Miscarriage, Recurrent
The Role of Hydrosalpinx in Recurrent Miscarriage
Miscarriage affects one in five pregnancies and little progress has been made in understanding and treating this distressing condition. C. trachomatis is the most common sexually transmitted infection in the UK. C.
- Conditions
- Abortion, Spontaneous, Miscarriage, Recurrent, Hydrosalpinx
- Trial name
- NCT03703401
- Testing
- Hysterosalpingo-contrast-sonogram
- Where
- United Kingdom
- Volunteers
- 137 people
- Sponsor
- University of Birmingham
Infertility Female, Recurrent Miscarriage
Study on the Association Between SXCI and RM and the Possible Genetic Mechanism
To determine whether there is higher incidence of skewed X chromosome inactivation(SXCI) in the recurrent miscarriage(RM) population compared with normal population, and verify the existing hypothesis of the possible genetic…
- Trial name
- NCT02504281
- Where
- China
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Miscarriage, Recurrent
Use of Cyclosporin A for the Treatment of Recurrent Miscarriage
The purpose of this study is to determine whether Cyclosporin A (CsA) - an immunosuppressant drug - in early pregnancy will reduce the risk of miscarriage in women who had a history of unexplained recurrent miscarriages, as…
- Trial name
- NCT02706470
- Testing
- Cyclosporin A, Dydrogesterone
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Fudan University
Recurrent Miscarriage
Low-dose Interleukin-2 in Women With Unexplained Miscarriages
The purpose of this study is to demonstrate the ability of low dose IL-2 to stimulate peripheral blood Tregs of women with unexplained repeated early spontaneous miscarriages for development of a therapy to prevent fetal…
- Trial name
- FaCIL-2 (NCT03970954)
- Testing
- low-dose IL-2
- Where
- 3 sites in France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Recurrent Miscarriage, Antiphospholipid Syndrome
Use of Warfarin After the First Trimester in Pregnant Women With APS
Evaluation of shifting to oral vitamin K antagonist after the first trimester instead of using low molecular weight heparin (LMWH) throughout pregnancy in pregnant women with antiphospholipid syndrome (APS)
- Trial name
- NCT02303171
- Testing
- Enoxaparin, Warfarin
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Mohamed Sayed Abdelhafez
Recurrent Pregnancy Loss
Effectiveness of Aspirin in Compare With Heparin Plus Aspirin in Recurrent Pregnancy Loss Treatment
This study evaluated the effect of anticoagulant treatment on the live-birth rate in women with a history of at least two continuous unexplained miscarriages or thrombophilia.
- Trial name
- NCT01542411
- Where
- Iran
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Yazd Medical University
Miscarriage, Recurrent
Sildenafil Citrate in Early Unexplained Recurrent Pregnancy Loss
Recurrent unexplained spontaneous miscarriage (RSM) is defined as three consecutive pregnancy loss prior to 20 weeks from the last menstrual period. 1% to 2% of women experience RSM. Treatment of URSM is a challenging issue.
- Trial name
- NCT03766594
- Testing
- Sildenafil Citrate, Folic Acid
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Recurrent Miscarriage
Effect of Prednisolone Treatment on Uterine Natural Killer Cells
This study aims to investigate the role of uNK cells and the association with prednisolone.
- Trial name
- NCT03902912
- Testing
- Prednisolone
- Where
- Hong Kong
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Cervical Insufficiency
Patient Attitudes Toward Ultrasound Measurement of Cervical Length
The investigators propose a prospective evaluation of methods to assess cervical length for uncomplicated singleton gestations between 18-28 weeks presenting to the MFM office for routine mid pregnancy ultrasound.
- Trial name
- TVUS (NCT01482039)
- Testing
- Sequential ultrasound, Transvaginal ultrasound
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Intermountain Women and Children's Research
Miscarriage, Recurrent, Abortion, Habitual
Intravenous Immunoglobulin (IVIG) for Treatment of Unexplained Secondary Recurrent Miscarriage
Recurrent miscarriage is a prevalent reproductive problem that affects many couples who are trying to establish a family. This clinical study will evaluate the effectiveness of intravenous immunoglobulin (IVIG) in improving the…
- Trial name
- NCT00606905
- Testing
- Gamimune N or Gamunex 10%, normal saline
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Chicago
Recurrent Miscarriage
Walking and Dietary Modification for Recurrent Early Miscarriages
This study is part of a big one aiming to evaluate how lifestyle interventions during pregnancy affect obstetric results, neonatal metabolism and the intelligence of the offspring (study not yet completed).
- Trial name
- W&D (NCT03023137)
- Testing
- Walking & dietary modification
- Where
- Brazil
- Volunteers
- 480 people
- Sponsor
- Hospital dos Servidores do Estado do Rio de Janeiro
Recurrent Miscarriage
Use of Platelet Indices for Prediction of Recurrent Miscarriage
Platelet indices might be a marker for platelet activation, and thus could predict thrombosis. This might be the cause in some cases of recurrent miscarriage.
- Trial name
- NCT03710226
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Rania Hassan Mostafa
Unexplained Recurrent Miscarriage
Hydroxychloroquine and Unexplained Recurrent Miscarriage
Recurrent miscarriage affects women of childbearing age worldwide. Vascular endothelial dysfunction and immunological impairment are associated with recurrent miscarriage To date, there is no effective or optimal therapeutic…
- Trial name
- NCT04228263
- Testing
- Hydroxychloroquine, Folic Acid, Low-dose aspirin
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Assiut University
Miscarriage, Recurrent
Prediction of Recurrent Pregnancy Loss by a New Thrombophilia Based Genetic Risk Score
Recurrent pregnancy loss (RPL) is a clinical problem affecting 1-5% of couples of reproductive age. The contribution of thrombophilia to RPL is disputed.
- Trial name
- TiC-RPL (NCT03336463)
- Where
- 8 sites in Spain, United Kingdom
- Volunteers
- 364 people
- Sponsor
- Ferrer inCode, S.L.
Recurrent Pregnancy Loss, Recurrent Implantation Failure
Use of Metabolomics for the Identification of Endometrial Biomarkers for IRPL and RIF After in Vitro Fertilization
It is a case-control study composed of 3 groups : 2 cases groups (RIF and IRPL) already composed as part of a pre-existing research project and 1 control group including patients undergoing ART for male factor infertility.
- Trial name
- ENDOMETAB (NCT03690830)
- Testing
- metabolomics analysis
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers
Thrombophilia With Recurrent Pregnancy Loss
Diagnosis and Treatment Strategy of Recurrent Spontaneous Abortion Associated With Thrombophilla
In this clinical cohort study, the investigators observe the efficacy of low molecular weight heparin in the treatment of thrombophilia with recurrent pregnancy loss with a prospective randomized controlled trial.
- Trial name
- NCT02986594
- Testing
- Aspirin, Heparin
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
IVF Outcomes
HELIOS: Human Embryo Illumination to Enhance Development
Embryos need a lot of energy to grow, but as women get older, the "power plants" of the cells (called mitochondria) don't work as well. This makes it harder for embryos to develop normally.
- Trial name
- HELIOS (NCT07311928)
- Testing
- Photobiomodulation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Columbia University
Miscarriage, Early Pregnancy Loss
Cohort of Patients Presenting Unexplained Recurrent Miscarriages and Identification of Early Miscarriage Recidivism Factors
About 1 to 3% of women of childbearing age suffer repeated early spontaneous miscarriages (RCF) defined by at least 3 fetal losses before 14 weeks of gestation.
- Trial name
- FALCO (NCT05557201)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris