Clinical trials: Recurrent Aphthous Ulcer
Recurrent Aphthous Stomatitis
A Study on Sumac Mouth Rinse for Treating Recurrent Aphthous Stomatitis
This randomized controlled clinical study aims to evaluate the effectiveness of a Sumac mouth rinse in the management of recurrent aphthous stomatitis (RAS).
- Trial name
- SUMAC-RAS (NCT07229469)
- Testing
- Sumac mouth rinse, Tantum Verde mouth rinse
- Where
- Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Aphthous Ulcer
The Efficacy of Nigella Sativa Oil Mouth Rinse in the Management of Recurrent Minor Aphthous Ulcer
This research aims to investigate the effectiveness of Nigella Sativa Oil Mouth Rinse application both clinically and biochemically as a suitable affordable treatment modality for Management of Recurrent Minor Aphthous Ulcer
- Trial name
- NCT06013202
- Testing
- Nigella Sativa Oil Mouth Rinse, isotonic (normal saline) with concentration 0.90% of sodium chloride (NaCl)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nada Sherif
Oral Ulcer
Probiotic Lozenges for Treatment of Recurrent Aphthous Stomatitis
The application of host-modulating bacteria for therapeutic purposes is one of the strongest emerging fields. Probiotics are live microorganisms, which, when administered in an adequate amount, confer a health benefit on the host…
- Trial name
- RAS (NCT04383236)
- Testing
- Probiotics, Oracure oral gel
- Volunteers
- 120 people
- Sponsor
- Reham Lotfy Aggour
Recurrent Aphthous Stomatitis
Topical Hyaluronic Acid and Recurrent Aphthous Stomatitis.
This study was conducted to estimate the hypothesis that the topical hyaluronic acid mouthwash have no role in the treatment of recurrent aphthous stomatitis
- Trial name
- NCT04265001
- Testing
- Hyaluronic acid in the form of hyaluronan sodium 25 mg/100 ml as a mouthwash
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Minor Recurrent Aphthous Stomatitis Lesions
The Effect of 2-DeNT Oral Topical Powder on Minor Recurrent Aphthous Ulcer
This is a prospective, randomized, blinded, placebo-controlled, crossover clinical trial to evaluate the efficacy of 2-DeNT oral topical powder in the treatment of recurrent aphthous stomatitis (RAS).
- Trial name
- NCT02142543
- Testing
- 2-DeNT powder
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Stomatitis, Aphthous Ulcer
Non-Thermal Plasma vs. Low-Level Laser Therapy for Recurrent Oral Ulcers
The goal of this clinical trial (pilot study) is to evaluate the feasibility and preliminary effectiveness of Non-Thermal Plasma (NTP) in treating pain and accelerating healing in 50 patients with Recurrent Oral Ulcers (ROUs).
- Trial name
- NCT07322666
- Testing
- Non-Thermal Plasma (NTP), Low-Level Laser Therapy (LLLT)
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- National Institute of Nuclear Research - Mexico
Aphthous Stomatitis
Therapeutic Effects of "Ibuprofen, Diphenhydramine and Aluminium MgS" on Recurrent Aphthous Stomatitis
The intention of the study is to study the effects of Ibuprofen, Diphenhydramine and Aluminium MgS in decreasing the signs of recurrent aphthous stomatitis (RAS)
- Trial name
- NCT01293968
- Testing
- Ibuprofen, Diphenhydramine and Aluminium MgS, Diphenhydramine and Aluminium MgS
- Where
- 2 sites in Iran
- Volunteers
- 37 people
- Sponsor
- Qazvin University Of Medical Sciences
Recurrent Mouth Ulcers
Omega-3 and Quality of Life in Recurrent Aphthous Stomatitis Patients
The study aims at evaluating the effect of omega-3 on patients suffering recurrent oral aphthous ulcers
- Trial name
- NCT01831453
- Testing
- omega-3
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- October 6 University
Recurrent Aphthous Stomatitis
Clinical Evaluation of Fluid Extract of Chamomilla Tincture for Oral Aphthae
Recurrent aphthous stomatitis is a difficult to treat and quite common chronic inflammatory disease of the oral mucosa. This study evaluates the fluid extract from Chamomilla recutita's safety and effectiveness in treatment of…
- Trial name
- NCT01122147
- Testing
- chamomilla tincture mouthwash
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Mashhad University of Medical Sciences
Aphthous Stomatitis, Recurrent, Aphthous Stomatitis
Effect of Alum Stone Containing Mucosal Adhesive Patches on Healing of Recurrent Aphthous Stomatitis
The evaluation of recurrent aphthous stomatitis (RAS) was performed by an oral medicine specialist, who relied on the clinical manifestations of the condition.
- Conditions
- Aphthous Stomatitis, Recurrent, Aphthous Stomatitis, Aphthous Ulcer
- Trial name
- NCT06960278
- Testing
- Size of aphthous lesions and degree of pain assessed at days 1, 3, and 5., Control, ALUMSTONE
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Of Anbar
Recurrent Aphthous Stomatitis
A Trial of Pentoxifylline for the Treatment of Recurrent Aphthous Stomatitis
This is a randomized, double blind, placebo controlled trial of the use of pentoxifylline (oxpentifylline) for the treatment of recurrent mouth ulcers.
- Trial name
- NCT00315679
- Testing
- Pentoxifylline (also known as oxpentifylline)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Manchester University NHS Foundation Trust
Oral Lichen Planus, Recurrent Aphthous Stomatitis
Topical "Non-Aromatic Very Rich in Steranes" (NAVS) Naphthalan for the Treatment of Oral Mucosal Diseases
This study evaluates the effectiveness of topical NAVS naphthalan in the treatment of oral lichen planus (OLP) and recurrent aphthous stomatitis (RAS).
- Trial name
- NCT02920658
- Testing
- NAVS Naphthalan, 0.05% Betamethasone dipropionate
- Where
- Croatia
- Volunteers
- 57 people
- Sponsor
- Ivan Alajbeg
Recurrent Aphthous Stomatitis
Efficacy and Safety Study of Yunnan Baiyao on Minor Recurrent Aphthous Stomatitis
Recurrent aphthous stomatitis (RAS) is a common recurrent oral disorder with no curative treatment available to date. The challenge remains in patients that do develop drug resistance and/or secondary infection, although topical…
- Trial name
- NCT01652625
- Testing
- Yunnan Baiyao toothpaste
- Volunteers
- 227 people
- Sponsor
- Peking University
Recurrent Aphthous Stomatitis
Effect of Sodium Lauryl Sulfate on Recurrent Aphthous Stomatitis
Sodium lauryl sulfate (SLS) is an anionic detergent that has been used as the major or sole surfactant in most dentifrices. But it is known to local irritating factor to oral mucosa and skin and results in many side effects.
- Trial name
- NCT01501409
- Testing
- sodium lauryl sulfate
- Volunteers
- 90 people
- Sponsor
- Yonsei University
Treatment of Minor Aphthous Ulcers
Evaluation of Topical Probiotic Gel Versus Triamcinolone in Minor Recurrent Aphthous Ulcers
This study looks at a new way to treat minor recurrent aphthous ulcers. These ulcers are painful, round or oval sores that show up on the soft, non-chewing surfaces of the mouth (like the inside of the cheeks or lips).
- Trial name
- NCT07672730
- Testing
- Probiotic gel, Triamcinelone acetonide
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Aphthous Ulcer Recurrent
Corchorus Olitorius Buccal Films for the Treatment of Recurrent Minor Aphthous Ulcerations
A methanol extract of Corchorus olitorius edible plant was perpared for extration of glycosideal compounds. the extract was tested for its efficacy as antiinflammatory and analgesic activity invitro and approved by the…
- Trial name
- NCT05392842
- Testing
- Corchorus Olitorius Buccal fast dissolving Films, plain mucoadhesive fast dissolving film
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Deraya University
Recurrent Aphtous Stomatitis
Randomized Double Blind Controlled Trial Comparing the Safety and Efficacy of Apremilast Versus Placebo in Severe Forms of Recurrent Aphthous Stomatitis
The objective of the study is to assess the superiority of apremilast in comparison with placebo to achieve Complete Remission (CR) of oral ulcers at Week 12, in patients with severe Recurrent aphtous stomatitis resistant or…
- Trial name
- PREMS (NCT04227314)
- Testing
- Apremilast
- Where
- 21 sites in France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Rouen
Recurrent Aphthous Stomatitis
Apremilast for RAS
Determination of treatment efficacy and safety of Apremilast in patients with RAS
- Trial name
- NCT03690544
- Testing
- Apremilast 30mg
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Drug Effect, Drug Effect Prolonged
Niosomal Propolis as Oromucoadhesive Film: In-vitro, Ex-vivo & In-vivo Investigations
A total of 24 patients suffering from RAU, they were divided into two groups each included 12 patients. The first group was treated by the propolis mucoadhesive film and the second group received the film without the active…
- Trial name
- NCT03615820
- Testing
- Niosomal PPE oromucoadhesive film, Oromucoadhesive film
- Where
- 2 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- British University In Egypt
Aphthous Stomatitis
Efficacy and Safety of BNP105 in the Treatment of Recurrent Aphthous Stomatitis
The purpose of this study is to evaluate the efficacy and safety of BNP105 in the treatment of recurrent aphthous stomatitis.
- Trial name
- NCT05772338
- Testing
- BNP105 (25 + 25 + 15)
- Where
- 2 sites in Brazil
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- EMS