Clinical trials: Recurrent Ischemic Stroke
Ischemic Stroke, Paroxysmal Atrial Fibrillation
Paroxysmal Atrial Fibrillation in Patients With Acute Ischemic Stroke
The purpose of this study is to estimate the clinical relevance of monitoring patients with acute ischemic stroke with 48 hours' inpatient cardiac telemetry in relation to evaluate the presence of brief runs of premature atrial…
- Conditions
- Ischemic Stroke, Paroxysmal Atrial Fibrillation, Premature Atrial Complexes
- Trial name
- NCT02610803
- Where
- Denmark
- Volunteers
- 863 people
- Sponsor
- Odense University Hospital
Embolic Stroke
Shuxuetong for Prevention of Recurrence in Acute Cerebrovascular Events With Embolism
This is a randomized, double blind, placebo-controlled, parallel, multicenter research in order to evaluate the effect of Shuxuetong injection in prevention of symptomatic or asymptomatic new cerebral infarction within 10 days.
- Trial name
- SPACE (NCT03090113)
- Testing
- Shuxuetong Injection
- Where
- 48 sites in China
- Volunteers
- 2,416 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Acute Ischemic, Intracerebral Hemorrhage
The Stroke Aetiology and VascuLar Disease in Stroke and TIA Study - A Clinical Study Analysing the Effects on Cardiovascular Health and Disease With an Extended Investigation Into Conditions Causative of Stroke and Concomitant Cardiovascular Disease in Patients Admitted for Acute Stroke or TIA
Annually, about 4000 Swedes suffer a recurrent stroke, and for many, their lives change dramatically. To prevent recurring strokes, knowledge about the individual's risk of recurrence is needed to tailor an effective preventive…
- Conditions
- Stroke, Acute Ischemic, Intracerebral Hemorrhage, TIA, Hypertension
- Trial name
- SALSA (NCT07491744)
- Testing
- Extended assessment
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Region Stockholm
Stroke Recurrence, Cardiovascular Events
Post-stroke Depression Treatment Effect on Stroke Recurrence
It is not clear whether depresssion can predispose, or precipitate stroke recurrence in patients with stroke. We sought the relationship of post stroke depression with stroke recurrence.
- Conditions
- Stroke Recurrence, Cardiovascular Events, Depression
- Trial name
- STROKE (NCT04776226)
- Testing
- Citalopram
- Where
- Turkey (Türkiye)
- Volunteers
- 1,230 people
- Sponsor
- Ege University
Mini-Stroke
Intensified Secondary Prevention Intending a Reduction of Recurrent Events in TIA and Minor Stroke Patients
Patients after TIA or Stroke are at high risk of experiencing a new stroke or myocardial infarction. Poor adherence to evidence based secondary prevention regimens is frequently seen.
- Trial name
- INSPiRE-TMS (NCT01586702)
- Testing
- Patient centered structured support program
- Where
- Germany
- Volunteers
- 2,082 people
- Sponsor
- Charite University, Berlin, Germany
Intracranial Vascular Disorders
Mechanisms of Early Recurrence in Intracranial Atherosclerotic Disease
The objective of this study is to determine the mechanisms of stroke in patients with Intracranial Atherosclerotic Disease (IAD) by specifically evaluating limitations of antegrade flow through the stenotic artery, distal tissue…
- Trial name
- MyRIAD (NCT02121028)
- Where
- 10 sites in United States
- Volunteers
- 105 people
- Sponsor
- University of Miami
Stroke
Preventing Recurrence of Thromboembolic Events Through Coordinated Treatment in the District of Columbia
The purpose of this study is to refine and evaluate the Preventing Recurrence of Thromboembolic Events through Coordinated Treatment in the District of Columbia (PROTECT DC) intervention.
- Trial name
- PROTECT DC (NCT00703274)
- Testing
- PROTECT DC
- Where
- 6 sites in United States
- Volunteers
- 230 people
- Sponsor
- Georgetown University
Acute Ischemic Stroke, Active Cancer
Acute Ischemic Stroke in Patients With Active Cancer
The goal of this multicenter prospective observational study, conducted at 24 hospitals in Japan, is to learn about recurrent ischemic stroke in people with active cancer who develop acute ischemic stroke.
- Trial name
- CAT-AIS (NCT07819526)
- Where
- Japan
- Volunteers
- 500 people
- Sponsor
- Osaka University
Stroke, Transient Ischemic Attack
Clopidogrel With Aspirin in High-risk Patients With Acute Non-disabling Cerebrovascular Events II
The primary objective of this trial is to assess the effects of ticagrelor plus aspirin versus clopidogrel plus aspirin on reducing the 3-month risk of any stroke (both ischemic and hemorrhagic, primary outcome) when initiated…
- Trial name
- CHANCE-2 (NCT04078737)
- Testing
- Ticagrelor and Aspirin, Clopidogrel and Aspirin
- Where
- 214 sites in China
- Volunteers
- 6,412 people
- Sponsor
- Beijing Tiantan Hospital
Acute Ischemic Stroke
Clopidogrel Plus Aspirin in Acute Ischemic Stroke Following Thrombectomy and/or Intravenous Thrombolysis (CoPrime)
Stroke is a common cause of disability. The most common type of stroke, an ischemic stroke, is caused by a blood vessel in the brain getting blocked by a clot.
- Trial name
- CoPrime (NCT06638151)
- Testing
- aspirin + clopidogrel, Aspirin
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of Alberta
Ischemic Stroke, Transient Ischemic Attack
Efficacy of Ticagrelor Plus Aspirin in Mild Non-cardioembolic Ischemic Stroke
This is a randomized, controlled, active comparator arm, outcome assessor blind, parallel group design on 90 patient with diagnosis of ischemic stroke admitted in Bou-Ali Sina Hospital, Sari,Iran.The aim of study is assess the…
- Trial name
- TACAMINIS (NCT04738097)
- Testing
- Ticagrelor 90mg, Clopidogrel 75 mg
- Where
- 2 sites in Iran
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mazandaran University of Medical Sciences
Acute Stroke, Transient Ischemic Attack
The Recurrence Study
The primarily goal of the research is to better understand progression of disease in patients who present with an acute stroke to the Hamad General Hospital (HGH) stroke and Transient Ischemic Attack (TIA) clinic.
- Trial name
- NCT03244215
- Testing
- Corneal Confocal Imaging, Magnetic resonance Imaging, Blood sample
- Where
- Qatar
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Stroke, Transient Ischemic Attack
Optimal Blood Pressure and Cholesterol Targets for Preventing Recurrent Stroke in Hypertensives
Stroke is one of the major causes not only of mortality, but of disease burden worldwide, because of residual disability and cognitive decline.
- Conditions
- Stroke, Transient Ischemic Attack, Hypertension
- Trial name
- ESH-CHL-SHOT (NCT01563731)
- Testing
- all approved antihypertensive drugs; all approved statins
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Istituto Auxologico Italiano
Ischemic Stroke, Digital Health
Prevention of Ischemic Stroke Recurrence Using Digital Technology Application
The goal of this study is to find out whether a comprehensive management program that uses a smart bracelet and a mobile app can help people who have had an ischemic stroke (a type of stroke caused by a blocked blood vessel in…
- Trial name
- DESIRE (NCT07825311)
- Testing
- Digital Prevention Management, Usual Stroke Secondary Prevention Management
- Where
- China
- Volunteers
- 1,696 people
- Sponsor
- Affiliated Hospital of Nantong University
Cardioembolic Stroke, Anticoagulant Therapy
Keeping Oral o Parental AnticoaguLation in the Acute Phase of Cardioembolic Ischemic Stroke
This is an observational, prospective, multicenter, cohort study in patients with cardioembolic stroke and previous oral or parenteral anticoagulant therapy.
- Conditions
- Cardioembolic Stroke, Anticoagulant Therapy, Stroke Recurrence, Haemorrhagic Transformation Stroke
- Trial name
- KOALA-IS (NCT05486351)
- Testing
- Observation
- Where
- 3 sites in France, Spain
- Volunteers
- 318 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Atrial Fibrillation
Posterior Wall And Left Atrial Appendage Empiric Electrical Isolation for Non-Paroxysmal Atrial Fibrillation
The purpose of this study is to evaluate the safety and effectiveness of empirical posterior wall isolation (PWI), left atrial appendage electrical isolation (LAAEI) and coronary sinus isolation (CSI) when compared to pulmonary…
- Trial name
- PLEA (NCT04216667)
- Testing
- Catheter ablation
- Where
- 16 sites in United States, Argentina and 5 more
- Volunteers
- 124 people
- Sponsor
- Montefiore Medical Center
Stroke, Stenosis
Abciximab for Prevention of Stroke Recurrence Before Endarterectomy in Symptomatic Carotid Stenosis
The purpose of the present prospective, randomized, double-blind, double dummy controlled multicenter pilot study is to investigate whether abciximab, compared with aspirin, is able to reduce the rate of recurrent ischemic…
- Trial name
- NCT00126139
- Testing
- Abciximab
- Where
- 5 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Stroke (CVA) or TIA, Stroke Recurrence
NORA-HOME: An Ambulatory Multimodal Monitoring Model In Patients With Minor Stroke And Transient Ischemic Attacks
In this project, we aim to validate a Home Hospitalization plan for patients with TIA or minor stroke. Our hypothesis is that our Multimodal Home Hospitalization program (NORAHOME) for patients with TIA and minor stroke is safe…
- Trial name
- NORAHOME (NCT07500116)
- Testing
- Home hospitalization
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Vertebral Artery Stenosis
Drug Eluting Stenting and Short Dual Antiplatelet Therapy for Preventing Recurrent Stroke in Vertebral Stenosis Registry Study
This is a prospective, multi-center, registry study exploring the duration of dual antiplatelet therapy (DAPT) after drug-eluting stent(DES) treatment of symptomatic vertebral artery atherosclerotic stenosis.
- Trial name
- M Short DAPT (NCT06683300)
- Testing
- DAPT for 3 months after vertebral artery stenting
- Where
- China
- Volunteers
- 520 people
- Sponsor
- Beijing Tiantan Hospital
Cerebrovascular Accident, Transient Ischemic Attack
The Post Stroke Preventive Trial (PREVENT). A RCT Nested in a Cohort Study
Patients with a diagnosis of stroke or TIA, who are already included in the RIALTO-cohort study are asked to participate in a RCT after discharge from hospital.
- Conditions
- Cerebrovascular Accident, Transient Ischemic Attack, Myocardial Infarction
- Trial name
- PREVENT (NCT00253097)
- Testing
- Intervention
- Where
- 2 sites in Denmark
- Volunteers
- 353 people
- Sponsor
- Hvidovre University Hospital