Clinical trials: Recurrent Miscarriage
Care in Women With History of Recurrent Miscarriage
Nursing Counseling on Stress and Depression for Women With Recurrent Miscarriage
Recurrent miscarriage is a frustrating event for couples. The purpose of this randomized, controlled trial was to examine the effectiveness of nursing counseling on sleep quality, depression, stress, and social support in women…
- Trial name
- NCT04361747
- Testing
- nursing counseling
- Volunteers
- 62 people
- Sponsor
- National Cheng-Kung University Hospital
Infertility, Recurrent Miscarriage
Effect of Influenza Vaccination on Donor Egg Recipient Outcomes
In this study the investigators propose a randomized controlled trial to evaluate the effect of influenza vaccination on clinical pregnancy rates among women undergoing in vitro fertilization as donor egg recipients.
- Trial name
- DE-FluVac (NCT02946177)
- Testing
- Influenza Vaccine, Sterile Saline
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Female, Recurrent Miscarriage
Assessment of Natural Killer Cells in Unexplained Recurrent Pregnancy Loss
To assess natural killer cells frequency and activation in cases of unexplained recurrent abortion in comparison to fertile cases 2. . To study the expression of stimulatory receptors of natural killer cell.
- Conditions
- Female, Recurrent Miscarriage, Unexplained Pregnancy Loss
- Trial name
- NCT03941470
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Recurrent Miscarriage
Sim (Scratch in Miscarriage) Study
There is increasing amount of evidence which suggests that miscarriage is related to a primary endometrial problem. Recent cochrane meta-analysis (March 2015) has proven that endometrial scratch improves live birth in women who…
- Trial name
- SiM (NCT02681627)
- Testing
- Endometrial scratch, Touching the cervix
- Where
- United Kingdom
- Volunteers
- 109 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Miscarriage, Recurrent
Sildenafil Citrate in Early Unexplained Recurrent Pregnancy Loss
Recurrent unexplained spontaneous miscarriage (RSM) is defined as three consecutive pregnancy loss prior to 20 weeks from the last menstrual period. 1% to 2% of women experience RSM. Treatment of URSM is a challenging issue.
- Trial name
- NCT03766594
- Testing
- Sildenafil Citrate, Folic Acid
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Unexplained Recurrent Miscarriage and Recurrent Implantation Failure
A Preliminary Study About Unexplained Recurrent Miscarriage and Repeated Implantation Failure Patients Treated With Low-dose Lymphocyte Immunotherapy
Recurrent miscarriage(RM) and recurrent implantation failure (RIF) are clinical challenge for clinicians and patients who are desperate for a healthy child.The specific etiology contains chromosomal abnormalities, reproductive…
- Trial name
- immunotherapy (NCT03081325)
- Testing
- low-dose lymphocyte immunotherapy
- Where
- China
- Volunteers
- 292 people
- Sponsor
- Nanjing University
Recurrent Miscarriage, Infertility
EmbryoGen/ Blastgen for Couples With Implantation Problems or Previous Miscarriage
EmbryoGen and BlastGen contain the cytokine growth factor Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), which has been documented to give significant benefit to this difficult group of patients.
- Trial name
- BlastGen (NCT02305420)
- Testing
- EmbryoGen/ BlastGen media, Standard Cook sequential media
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- FertilitySA
Recurrent Miscarriage, Antiphospholipid Syndrome
Timing of Initiation of LMWH Administration in Pregnant Women With APS
Evaluation of the effect of altering the timing of initiation of low molecular weight heparin (LMWH) administration on the pregnancy outcomes in women with antiphospholipid syndrome (APS)
- Trial name
- NCT02326051
- Testing
- Enoxaparin
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Mohamed Sayed Abdelhafez
Miscarriage, Recurrent
Prediction of Recurrent Pregnancy Loss by a New Thrombophilia Based Genetic Risk Score
Recurrent pregnancy loss (RPL) is a clinical problem affecting 1-5% of couples of reproductive age. The contribution of thrombophilia to RPL is disputed.
- Trial name
- TiC-RPL (NCT03336463)
- Where
- 8 sites in Spain, United Kingdom
- Volunteers
- 364 people
- Sponsor
- Ferrer inCode, S.L.
Recurrent Miscarriages
Maternal Embryo Interaction in Recurrent Miscarriages
Background of the study: The etiology of recurrent miscarriage (RM, defined as three or more consecutive miscarriages without any proven maternal or fetal cause), remains undiagnosed in more than 50% of cases.
- Trial name
- MEER (NCT03156491)
- Where
- Netherlands
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Recurrent Miscarriage
Intralipid Related Effect on NKcells in Patients With Unexplained Recurrent Spontaneous Abortion
Evaluating the effect of intralipid on the natural killer cells
- Trial name
- NCT03132779
- Testing
- Intralipid
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ahmed Mohamed Bahaa Eldin Ahmed
Recurrent Miscarriage
Walking and Dietary Modification for Recurrent Early Miscarriages
This study is part of a big one aiming to evaluate how lifestyle interventions during pregnancy affect obstetric results, neonatal metabolism and the intelligence of the offspring (study not yet completed).
- Trial name
- W&D (NCT03023137)
- Testing
- Walking & dietary modification
- Where
- Brazil
- Volunteers
- 480 people
- Sponsor
- Hospital dos Servidores do Estado do Rio de Janeiro
Recurrent Miscarriage
Low Molecular Weight Heparin in Recurrent Miscarriage With Negative Antiphospholipid Antibodies
Recurrent miscarriage (RM) is traditionally defined as three or more consecutive miscarriages occurring before 20 weeks post-menstruation.
- Trial name
- LMWH-APAN (NCT01608347)
- Testing
- LMWH+Folic acid, Folic Acid
- Volunteers
- 228 people
- Sponsor
- Omar Mamdouh Shaaban
Ovarian Reserve, Miscarriage, Recurrent
The Effect of the Ovarian Reserve on the Recurrent Pregnancy Loss
The purpose of this study is to determine whether ovarian reserve is related to recurrent pregnancy loss
- Trial name
- NCT03009370
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Recurrent Pregnancy Loss, Miscarriage
Hydroxychloroquine (HCQ) for Recurrent Pregnancy Loss
Recurrent pregnancy loss (RPL) affects 5% of couples trying to achieve parenthood. Most cases of RPL are unexplained and have no effective treatment to improve the likelihood of a pregnancy resulting in a live birth.
- Trial name
- NCT02379650
- Testing
- Hydroxychloroquine (HCQ)
- Where
- 2 sites in United States
- Sponsor
- University of Utah
Miscarriage, Recurrent
Use of Cyclosporin A for the Treatment of Recurrent Miscarriage
The purpose of this study is to determine whether Cyclosporin A (CsA) - an immunosuppressant drug - in early pregnancy will reduce the risk of miscarriage in women who had a history of unexplained recurrent miscarriages, as…
- Trial name
- NCT02706470
- Testing
- Cyclosporin A, Dydrogesterone
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Fudan University
Recurrent Miscarriage
Expression of EPK in Recurrent Miscarriage
The present study is based on hypotheses that some as yet unknown genetic factors may result in recurrent miscarriage (RM). Consequently, the main aim of this study was to gain new information about the underlying genetic causes…
- Trial name
- EPK-RM (NCT02694367)
- Testing
- Investigate the MAP kinase signaling pathways through ERK and p-ERK proteins
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Assiut University
Recurrent Miscarriage
Genetic Abnormalities and Oxidative Stress in Sperm as Cause of Recurrent Miscarriage.
In recurrent miscarriage, the male factor has been poorly evaluated. In fact, in the vast majority of clinical protocols of recurrent miscarriage, the sperm is not considered or assessed.
- Trial name
- NCT00447395
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Recurrent Pregnancy Loss, Recurrent Miscarriage
A Multi-center, Placebo-controlled Study to Evaluate NT100 in Pregnant Women With a History of Unexplained Recurrent Pregnancy Loss (RPL)
This is a randomised, double blind, multi-center, placebo-controlled study of subcutaneous NT100 in pregnant women with a history of unexplained recurrent pregnancy loss.
- Trial name
- RESPONSE (NCT02156063)
- Testing
- NT100
- Where
- 19 sites in United Kingdom
- Volunteers
- 150 people
- Sponsor
- Nora Therapeutics, Inc.
Secondary Recurrent Miscarriage
Trial of the Efficacy of Intravenous Immunoglobulin for Treating Women With Unexplained Secondary Recurrent Miscarriage
The investigators want to test whether infusions of intravenous immunoglobulin - a blood product known to modify immune responses - in early pregnancy will increase the chance of a subsequent live birth in women with three or…
- Trial name
- NCT00722475
- Testing
- Intravenous immunoglobulin, Human albumin
- Where
- Denmark
- Volunteers
- 82 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet