Clinical trials: Recurrent Pericarditis, active
Recurrent Pericarditis
CardiolRx in Recurrent Pericarditis (MAVERIC Phase-3)
Multi-center, randomized, double-blind, placebo-controlled, phase-3 Trial. Patients with a history of recurrent pericarditis who are being treated with an IL-1 blocker for at least 12 months, scheduled to be discontinued, will be…
- Trial name
- MAVERIC (NCT06708299)
- Testing
- CardiolRx
- Where
- 27 sites in United States, Canada and 2 more
- Volunteers
- 110 people
- Sponsor
- Cardiol Therapeutics Inc.
Pericarditis, Pericarditis Acute
Phase 2/3 Study of Participants With Recurrent Pericarditis Evaluating the Efficacy and Safety of KPL-387
This study is being done to demonstrate whether KPL-387 is an effective and safe treatment for recurrent pericarditis.
- Conditions
- Pericarditis, Pericarditis Acute, Recurrent Pericarditis
- Trial name
- PASTORALE (NCT07010159)
- Testing
- KPL-387
- Where
- 66 sites in United States, Canada and 8 more
- Volunteers
- 325 people
- Sponsor
- Kiniksa Pharmaceuticals International, plc
Recurrent Pericarditis
REgiStry Of the NAtural History of recurreNt periCarditis in pEdiatric and Adult Patients
The registry will focus on furthering the understanding of the natural history of recurrent pericarditis (RP), as well as document RP-related clinical, health-related quality of life (HRQoL), and economic burden and will assist…
- Trial name
- RESONANCE (NCT04687358)
- Where
- 29 sites in United States
- Volunteers
- 500 people
- Sponsor
- Kiniksa Pharmaceuticals International, plc
Acute Pericarditis, Pericardial Effusion
Pericardial Fluid Analysis in Recurrent Pericarditis
This clinical trial aims to examine the biochemical and cytological features of pericardial effusion during acute and recurrent pericarditis and to understand the molecular factors responsible for pathogenesis.
- Conditions
- Acute Pericarditis, Pericardial Effusion, Pericardial Disease, Pericardial Fluid Exudate
- Trial name
- PEFLANA (NCT06293924)
- Testing
- Pericardiocentesis, Pericardiotomy, Cytofluorometry and Gene expression analysis
- Where
- Italy
- Volunteers
- 432 people
- Sponsor
- ASST Fatebenefratelli Sacco
Pericarditis
Pericardial Imaging Study
The pericardium is a thin, double-layered sac around the heart that helps reduce friction as the heart moves. When this sac gets inflamed, it is called pericarditis, which can cause serious health problems and even be…
- Trial name
- NCT07245849
- Testing
- 18F-FDG PET/CT
- Volunteers
- 44 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Recurrent Pericarditis, Heart Diseases
Transition to KPL-387 Monotherapy Dosing & Administration Study
The primary objective of this study is to characterize the efficacy and safety of dosing regimens used to transition from prior pericarditis therapies to KPL-387 monotherapy in participants with well-controlled recurrent…
- Conditions
- Recurrent Pericarditis, Heart Diseases, Pericarditis
- Trial name
- NCT07288216
- Testing
- KPL-387
- Where
- 47 sites in United States, Canada and 8 more
- Volunteers
- 120 people
- Sponsor
- Kiniksa Pharmaceuticals International, plc
Pericarditis
RUDRA Registry (Real-World Clinical Registry for Patients With Recurrent Pericarditis)
А multicenter, non-interventional real world clinical registry of patients with recurrent pericarditis. The main goal of the registry is to epidemiologically assess the pattern, clinical outcomes, and approaches to therapy in…
- Trial name
- NCT06517966
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Eurasian Association of Therapists
Recurrent Pericarditis
An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis
This is a study to understand if taking VTX2735 is safe and effective in participants diagnosed with Recurrent Pericarditis (RP).
- Trial name
- NCT06836232
- Testing
- VTX2735
- Where
- 20 sites in United States, Belgium and 2 more
- Volunteers
- 50 people
- Sponsor
- Zomagen Biosciences Ltd.
Idiopathic Recurrent Pericarditis
Study of the Safety and Efficacy of RPH-104 in Preventing Recurrences in Patients With Idiopathic Recurrent Pericarditis
The goal of this clinical trial is to evaluate the safety and efficacy of RPH-104 for long-term use in a population of patients with idiopathic recurrent pericarditis who completed the main study CL04018068.
- Trial name
- NCT05673902
- Testing
- RPH-104
- Where
- Russia
- Volunteers
- 17 people
- Sponsor
- R-Pharm International, LLC