Clinical trials: Recurrent Pterygium
Recurrent Pterygium
Recurrent Pterygium Surgery Using Mitomycin C With Limbal Conjunctival or Amniotic Membrane
To compare the outcomes of limbal conjunctival autograft (LCAG) versus amniotic membrane graft (AMG) when combined with intraoperative 0.02% mitomycin C (MMC) after pterygium removal in patients with recurrent pterygium.
- Trial name
- NCT01319721
- Testing
- MMC, LCAG, AMG
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Shiyou Zhou
Pterygium, Recurrence
Surgical Result of Pterygium Extended Removal Followed by Fibrin Glue Assisted Amniotic Membrane Transplantation
The treatment of pterygium is still quite controversial. Previous studies using a large incision for pterygium excision and a large graft and has reported a very low recurrence rate with the P.E.R.F.E.C.T. technique.
- Trial name
- NCT02015000
- Testing
- P.E.R.F.A.M.T
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Recurrent Pterygia
Amniotic Membrane Associated With Conjunctival Autograft Versus Conjunctival Autograft for Recurrent Pterygia
The purpose of this study is to compare amniotic membrane associated with conjunctival autograft versus conjunctival autograft alone in the treatment of recurrent pterygia.
- Trial name
- NCT00802620
- Testing
- Conjunctival autograft versus conjunctival autograft treatment for recurrent pterygia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Pterygium of Conjunctiva and Cornea
Recurrence Rate of Mini-SLET vs. Limbal-Conjunctival Autograft in Primary Pterygium Excision
To study the efficacy and safety of amniotic membrane transplantation as an adjunctive therapy after surgical excision of primary pterygium and compare the clinical outcomes with conjunctival autograft
- Trial name
- NCT03363282
- Testing
- Pterygium Excision
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Pterygium
Risk Factors and Biomarkers Associated With Recurrence After Excision of Primary Pterygium
This study looks at global gene expression in pterygium and found the derangement of matrix genes in particular to be a feature of pterygium.
- Trial name
- NCT01068496
- Where
- 2 sites in Singapore
- Volunteers
- 1 people
- Sponsor
- Singapore National Eye Centre
Neovascularization, Macular Degeneration
Ziv-aflibercept in Ocular Disease Requiring Anti-VEGF Injection
Background/aims: Aflibercept is an approved therapy for neovascular macular degeneration (AMD), diabetic macular edema (DME), retinal vein occlusion and other retinal conditions.
- Conditions
- Neovascularization, Macular Degeneration, Diabetic Retinopathy, Retinal Vein Occlusion
- Trial name
- Zaltrap (NCT02486484)
- Testing
- ziv-aflibercept
- Where
- Lebanon
- Volunteers
- 100 people
- Sponsor
- Rafic Hariri University Hospital
Glaucomas, Pterygium
Ologen(Oculusgen)-Glaucoma and Pterygium Historical Control Study in China Shanghai Sixth People's Hospital
The purpose of this study is to determine whether the ologen (OculusGen) Collagen Matrix are effective and safe to implant as an aid of glaucoma surgery and pterygium excision surgery.
- Trial name
- NCT00478790
- Testing
- ologen™ Collagen matrix implantation in glaucoma filtering surgery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Pro Top & Mediking Company Limited
Recurrent Pterygium
Subconjunctival Bevacizumab and Recurrent Pterygium
A study to research whether subconjunctival bevacizumab injection may potentially suppress neovascularization in pterygium, retarding and decreasing the size of recurrent pterygium.
- Trial name
- BRP (NCT01744756)
- Testing
- Bevacizumab
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Instituto de Olhos de Goiania
Recurrent Pterygium
Clinical Analysis of Recurrence Patterns Following Conjunctival Autografts for Pterygium Surgery
This study is conducted to evaluate its morphologic reproliferating patterns in patients with pterygium treated with the excision and conjunctival autograft.
- Trial name
- NCT02059837
- Testing
- recurrent pterygium excision and following grafting
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- Kyungpook National University Hospital
Pterygium
Preoperative Bevacizumab Injection in Primary Pterygium in Tunisian Patients
Purpose: To assess the efficacy and safety of a single preoperative intra-lesional bevacizumab injection in primary pterygium. Methods: The investigators conducted a randomized controlled interventional study from January 2019 to…
- Trial name
- NCT05314673
- Testing
- Preoperative Intra-lesional Bevacizumab Injection in primary pterygium, pterygium surgery without adjunctive therapy
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Hospital Fattouma Bourguiba
Pterygium
Role of Sub-Conjunctival Bevacizumab in Post Pterygium Excision Management
A pterygium is a fibrovascular growth originating from the conjunctiva that grows onto the surface of the cornea. Frequently, these pterygia will recur even after surgical resection.
- Trial name
- NCT01736449
- Testing
- Bevacizumab
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Arrowhead Regional Medical Center
Patients With Primary Nasal Pterygium
Effects of Ranibizumab in Primary Pterygium Surgery
Pterygium is a common ocular surface disease in Malaysia. Without treatment, it can lead to severe visual impairment. Recurrence is the commonest complication and novel treatment approaches are crucial to prevent vision loss.
- Trial name
- NCT04878835
- Testing
- intralesional ranibizumab
- Where
- Malaysia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Recurrent Pterygium
Conjunctival Autograft or Limbal Conjunctival Autograft for Recurrent Pterygium Using Mitomycin C
The purpose of this randomized clinical trial is to compare the efficacy and safety of intraoperative mitomycin C(MMC) combined with limbal conjunctival autograft(LCAG) or conjunctival autograft(CAG) for recurrent pterygium…
- Trial name
- NCT04463901
- Testing
- Pterygium excision, Intraoperative mitomycin C, Conjunctival autograft
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Sun Yat-sen University
Glaucomas, Pterygium
Ologen (OculusGen)-Glaucoma and Pterygium Historical Control Study in China Zhong-Shan Hospital
The purpose of this study is to determine whether the OculusGen Collagen Matrix are effective and safe to implant as an aid of glaucoma surgery.
- Trial name
- NCT00320957
- Testing
- OculusGen Biodegradable Collagen Matrix Implant
- Where
- China
- Volunteers
- 61 people
- Sponsor
- Pro Top & Mediking Company Limited