Clinical trials: Recurrent Ulcer Disease
Ulcerative Colitis
Effects of Carrageenan-Elimination Diet on Ulcerative Colitis Disease Activity
The study hypothesis is that withdrawal of carrageenan will lead to a longer, relapse free interval in patients with ulcerative colitis.
- Trial name
- NCT01065571
- Testing
- carrageenan, dietary intervention with no-carrageenan diet
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- University of Illinois Chicago
Mouth Sores
Post-marketing Study for the Evaluation of Profilm Mouth Sores
The study aims to assess the effect of Profilm Mouth Sores treatment for relieving symptoms caused by mouth sores. It will involve 35 participants and last around 14 days or until the sores heal, with three daily applications.
- Trial name
- NCT06741280
- Testing
- Profilm Mouth Sores
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- i+Med S.Coop.
Gastric or Duodenal Ulcers
Long-term Use of Takepron Capsules on the Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Low-dose Aspirin
The purpose of this study is to investigate the safety and efficacy of long-term administration of lansoprazole (Takepron) for up to 12 months in the routine clinical setting in patients receiving low-dose aspirin
- Trial name
- NCT02099682
- Testing
- Lansoprazole
- Volunteers
- 3,366 people
- Sponsor
- Takeda
Functional Pancreatic Neuroendocrine Tumor, Malignant Somatostatinoma
Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine Tumor
This phase I trial studies the side effects and best dose of veliparib when given together with capecitabine and temozolomide in treating patients with neuroendocrine tumor that has spread to other places in the body and usually…
- Conditions
- Functional Pancreatic Neuroendocrine Tumor, Malignant Somatostatinoma, Merkel Cell Carcinoma, Metastatic Adrenal Gland Pheochromocytoma
- Trial name
- NCT02831179
- Testing
- Capecitabine, Temozolomide, Veliparib
- Sponsor
- Vanderbilt-Ingram Cancer Center
Stomach Ulcer, Duodenal Ulcer
Efficacy and Safety of Lansoprazole on Gastric and Duodenal Ulcers in Patients Taking Nonsteroidal Anti-Inflammatory Drugs
The purpose of this study is to determine whether AG-1749 (lansoprazole), once daily (QD), is effective in preventing the recurrence of gastric and duodenal ulcers in patients receiving long term treatment with nonsteroid…
- Trial name
- NCT00787254
- Testing
- Lansoprazole, Gefarnate
- Where
- 68 sites in Japan
- Volunteers
- 366 people
- Sponsor
- Takeda
Gastric Ulcer, Duodenal Ulcer
Rabeprazole Specific Clinical Experience Investigation for the Long-term Combination Therapy With Low-dose Aspirin
To investigate the safety and efficacy of long-term combination therapy with rabeprazole and low-dose aspirin.
- Trial name
- NCT02423187
- Testing
- No Intervention
- Where
- 3 sites in Japan
- Volunteers
- 1,568 people
- Sponsor
- Eisai Co., Ltd.
Aphthous Stomatitis, Recurrent, Aphthous Stomatitis
Effect of Alum Stone Containing Mucosal Adhesive Patches on Healing of Recurrent Aphthous Stomatitis
The evaluation of recurrent aphthous stomatitis (RAS) was performed by an oral medicine specialist, who relied on the clinical manifestations of the condition.
- Conditions
- Aphthous Stomatitis, Recurrent, Aphthous Stomatitis, Aphthous Ulcer
- Trial name
- NCT06960278
- Testing
- Size of aphthous lesions and degree of pain assessed at days 1, 3, and 5., Control, ALUMSTONE
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Of Anbar
Gastric Ulcers Duodenal Ulcers Caused by Low-dose Aspirin
Long-term Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study)
The primary objective of this study to examine the long-term safety of rabeprazole 5 mg or 10 mg tablets administered once daily in participants who were confirmed to have no recurrence of gastric or duodenal ulcer by endoscopic…
- Trial name
- NCT01398410
- Testing
- Rabeprazole
- Where
- 50 sites in Japan
- Volunteers
- 405 people
- Sponsor
- Eisai Co., Ltd.
Peptic Ulcers
Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding Ulcer
The present study will compare the hemostasis-maintaining effects of intravenous omeprazole and ranitidine in patients with upper gastrointestinal hemorrhage that have undergone endoscopic hemostasis, to establish which…
- Trial name
- NCT00247130
- Testing
- Omeprazole, Ranitidine
- Where
- Japan
- Sponsor
- Keio University
Diabetes Mellitus, Diabetic Neuropathic Foot Ulcer
Off- Loading Shoe to Improve Healing and Prevention of Recurrence of Neuropathic Diabetic Plantar Foot Ulcers
It's a pilot prospective opened multicentric randomised study. We measure the efficiency and the safety of a new concept of off-loading shoe (SANIDIAB) compared with an old one (BAROUK) to treat chronic diabetic foot ulcer which…
- Trial name
- SANIBA (NCT01586481)
- Testing
- SANIDIAB, BAROUK
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetic Foot, Ulcer Foot
Diabetic Foot Ulcer Recurrence: Pilot Study
In this prospective pilot study, patients with DFU visiting the Indiana University Comprehensive Wound Center will be enrolled. Patients enrolled in the study will be followed for 16 weeks for wound closure(Phase A), and will…
- Trial name
- DFUCO (NCT03479242)
- Testing
- no interventions
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Indiana University
Peptic Ulcer/Erosions
Famotidine Compared With Pantoprazole to Prevent Recurrent Aspirin-Induced Peptic Ulcer/Erosion
Low-dose aspirin can prevent cerebral and cardiovascular accidents in individuals with symptomatic atherothrombotic disease, but its use is frequently limited by gastrointestinal side effects.
- Trial name
- NCT00843063
- Testing
- pantoprazole vs famotidine
- Where
- China
- Volunteers
- 161 people
- Sponsor
- Ruttonjee Hospital
Diabetic Foot, Diabetic Foot Ulcer
This Research Hypothesizes That the Use of a Rigid Rocker Sole Reduces the Recurrence Rate of Diabetic Foot Ulcers in Patients With Peripheral Neuropathy.
This research presents a randomized clinical trial which analyzes the efficacy of a rigid rocker sole in the reduction of the recurrence rate of plantar ulcers in diabetic foot patients.
- Trial name
- NCT02995863
- Testing
- Rigid Rocker Sole Footwear, Therapeutic Footwear
- Where
- Spain
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Oral Ulcer
Clinical Efficiency of Natural Herbal Based Gel.
This clinical trial was conducted in School of Dentistry, Islamabad from 15th June 2023 to 16th January 2024. A total 202 participants took part in study and were divided equally into two groups i.e Control group and Experimental…
- Trial name
- NCT06490289
- Testing
- Denpro oral gel
- Where
- Pakistan
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Diabetic Ulcer of Plantar Aspect of Left Foot, Diabetic Ulcer of Plantar Aspect of Right Foot
Nerve Decompression for Ulcer Recurrence Avoidance (DURA)
Anecdotal reports and scientific literature suggest that the risk of recurrence of diabetic foot ulcers can be minimized by nerve decompression procedures at anatomic sites of nerve pinching and entrapment.
- Conditions
- Diabetic Ulcer of Plantar Aspect of Left Foot, Diabetic Ulcer of Plantar Aspect of Right Foot, Diabetic Polyneuropathy
- Trial name
- DURA (NCT01762085)
- Testing
- nerve decompression
- Where
- 6 sites in United States
- Volunteers
- 120 people
- Sponsor
- Association of Extremity Nerve Surgeons
Diabetic Foot Ulcer (DFU)
AI Wound Alert & Home Management for Recurrent DFU
Diabetes is one of the major chronic diseases, and diabetic foot ulcer (DFU) is a significant adverse prognosis of diabetes. The recurrence of DFU after healing involves multiple risk factors, such as changes in foot loading…
- Trial name
- NCT07277010
- Testing
- Individualized follow-up care
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Arthritis, Cardiovascular Diseases
Celecoxib Versus Naproxen for Prevention of Recurrent Ulcer Bleeding in Arthritis Patients
The aim of this study is to compare celecoxib plus a PPI (esomeprazole) versus naproxen plus a PPI (esomeprazole) in preventing recurrent ulcer bleeding in arthritis patients with a history of ulcer bleeding who require…
- Conditions
- Arthritis, Cardiovascular Diseases, Cerebrovascular Disorders
- Trial name
- NCT00153660
- Testing
- Celecoxib(drug), Naproxen(drug)
- Where
- China
- Volunteers
- 514 people
- Sponsor
- Chinese University of Hong Kong
Active Peptic Ulcer Disease/GI Bleeding
Prevention of Recurrent Ulcer Bleeding in Patients With Idiopathic Gastroduodenal Ulcer
Patients with a history of idiopathic gastroduodenal ulcer bleeding face an increased risk of recurrent ulcer gastrointestinal bleeding.
- Trial name
- NCT03675672
- Testing
- Misoprostol Oral Tablet
- Where
- Hong Kong
- Volunteers
- 154 people
- Sponsor
- Chinese University of Hong Kong
Inflammatory Bowel Diseases, Clostridium Difficile Infection
ICON-2: FMT and Bezlotoxumab Compared to FMT and Placebo for Patients With IBD and CDI
This is a randomized controlled trial to assess the clinical and microbiological impacts of FMT in combination with Bezlotoxumab (bezlo) compared to FMT in combination with placebo in patients with both inflammatory bowel disease…
- Trial name
- ICON-2 (NCT03829475)
- Testing
- Bezlotoxumab, Fecal Microbiota Transplantation
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Brigham and Women's Hospital
Gastric Ulcers, Duodenal Ulcers
Long-term Extension Study of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose Aspirin
The purpose of this study is to evaluate the safety of TAK-438, once daily (QD), during long-term concomitant low-dose aspirin therapy in patients with a history of gastric or duodenal ulcer who require long-term therapy of…
- Trial name
- NCT01456247
- Testing
- TAK-438, Lansoprazole
- Where
- 76 sites in Japan
- Volunteers
- 439 people
- Sponsor
- Takeda