Clinical trials: Recurrent Urinary Tract Infection
Recurrent Uti
Uromune in Treating Recurrent Urinary Tract Infections in Women
To determine the effectiveness and safety of the vaccine Uromune in Canadian women with recurrent urinary tract infection.
- Trial name
- NCT04096820
- Testing
- Uromune
- Where
- Canada
- Volunteers
- 67 people
- Sponsor
- Queen's University
Recurrent Urinary Tract Infection
Periurethral vs Intravaginal Estrogen for Prevention of Recurrent Urinary Tract Infections
Due to rising antibiotic resistance, there has been a focus on non-antibiotic prophylactic measures for postmenopausal patients with recurrent urinary tract infections (rUTI), one of which is the safe and efficacious option of…
- Trial name
- TAPER (NCT05472779)
- Testing
- Periurethral application of estradiol cream, Intravaginal application of estradiol cream
- Where
- 4 sites in United States
- Volunteers
- 114 people
- Sponsor
- Stephanie Wang Zuo
Urinary Tract Infections
Fractional CO2 Vaginal LASER Therapy for Recurrent Urinary Tract Infection
Randomized controlled trial to determine clinical and microbiome difference between fractional CO2 Laser and vaginal estrogen in treating patients with recurrent urinary tract infection (UTI).
- Trial name
- NCT04301934
- Testing
- Mona Lisa Touch, Conjugated estrogen, Estradiol
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Hematuria, Urination Disorders
Rigid Versus Flexible Cystoscopy in Women
The study will help define the best tolerated approach to cystoscopy in women by randomly comparing flexible to rigid cystoscopy.
- Conditions
- Hematuria, Urination Disorders, Voiding Dysfunction, Recurrent Urinary Tract Infection
- Trial name
- NCT00214045
- Testing
- Flexible Cystoscopy, Rigid Cystoscopy
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Recurrent Urinary Tract Infection
EHR-integrated rUTI Texting Platform
The goal of this clinical trial is to compare a texting platform to usual care for managing recurrent urinary tract infections (UTI).
- Trial name
- Urotrust (NCT06035601)
- Testing
- EHR-integrated texting platform (Urotrust), Usual care
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Urologic Diseases, Patient Satisfaction
Developing a PROM for Recurrent Urinary Tract Infection
This study aims to develop and validate the first set of patient-reported outcome measures for recurrent urinary tract infection (UTI): the Recurrent UTI Symptom Scale and the Recurrent UTI Impact Questionnaire.
- Conditions
- Urologic Diseases, Patient Satisfaction, Pain, Chronic, Sexual Dysfunction
- Trial name
- NCT05086900
- Testing
- Non-interventional Cross-sectional Patient Reported Outcome Measure Development
- Where
- United Kingdom
- Volunteers
- 283 people
- Sponsor
- University of Reading
Urinary Tract Infections
Nutraceutical Efficacy for rUTI
This is a study designed to evaluate the efficacy of a nutraceutical as a non-antibiotic treatment to prevent recurrent urinary tract infections in women that have completed menopause and are on vaginal estrogen therapy.
- Trial name
- NCT03395288
- Testing
- D-Mannose
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Washington University School of Medicine
Recurrent Urinary Tract Infection, Urinary Tract Infections
Preventing Recurrent UTI With Vaginal Estrogen
Among postmenopausal women who suffer from recurrent urinary tract infections (UTI), vaginal estrogen therapy prevents UTI recurrences for 50% of sufferers.
- Conditions
- Recurrent Urinary Tract Infection, Urinary Tract Infections, Cystitis Recurrent
- Trial name
- PRUVE (NCT05551949)
- Testing
- Vaginal estradiol tablets
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Johns Hopkins University
Urinary Tract Infections, Recurrent
Methenamine Hippurate Versus Trimethoprim in the Prevention of Recurrent UTIs
Several methods are available for use in the prevention of recurrent urinary tract infections (UTIs) over the past few decades. These methods include suppressive antibiotics, estrogen cream, methenamine hippurate, d-mannose…
- Trial name
- NCT03077711
- Testing
- Trimethoprim, Methenamine hippurate
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Urinary Tract Infections
Efficacy and Mechanism of Action of Methenamine Hippurate (Hiprex™) in Women With Recurring Urinary Tract Infections.
The purpose of this study is to measure the concentration of formaldehyde in the urine of women with recurrent urinary tract infections on Hiprex; and then, assuming its urinary presence is confirmed at the proper acid urinary…
- Trial name
- NCT04709601
- Testing
- Hiprex
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Texas Southwestern Medical Center
Urinary Tract Infection, Recurrent Urinary Tract Infection
Effects of Antibiotic Prophylaxis on Recurrent UTI in Children
Approximately, 3% of males and 8% of females will develop a urinary tract infection (UTI) during childhood, and most of these will be effectively treated by short-term antibiotic therapy.
- Trial name
- NCT02357758
- Testing
- Antibiotic Prophylaxis
- Where
- Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Recurrent Urinary Tract Infection
D Mannose in Recurrent Urinary Tract Infections
Background- In recurrent urinary tract infections (RUTIs) usual prophylactic antibiotic regimes do not change the long term risk of recurrence. Objective- D-Mannose is a sugar, it sticks to E.
- Trial name
- NCT01808755
- Testing
- D Mannose, trimethoprim/sulfamethoxazole
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Urinary Tract Infection
Intravaginal LACTIN-V for Prevention of Recurrent Urinary Tract Infection
Recurrent urinary tract infections (RUTIS) continue to be a major health problem in women and are now complicated by increasing antibiotic resistance. New preventive approaches are needed.
- Trial name
- NCT00305227
- Testing
- Lactin-V
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Cancer
Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain
This is a phase III, randomized, double-blind, placebo-controlled, multicenter study of the clinical response to fentanyl sublingual spray as a treatment for breakthrough cancer pain.
- Trial name
- NCT00538850
- Testing
- Fentanyl sublingual spray
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- INSYS Therapeutics Inc
Recurrent Urinary Tract Infection
Vaginal Estrogen for the Prevention of Recurrent Urinary Tract Infection in Postmenopausal Women
The investigators would like to know if the use of vaginally applied estrogen can prevent the problem of repeated urinary tract infections (UTI) in women who have gone through menopause.
- Trial name
- VESPR (NCT01958073)
- Testing
- Conjugated Estrogen Vaginal Cream, Estradiol Ring
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of California, San Diego
Recurrent Urinary Tract Infection in Adult Women
Evaluating the Effect of the Probiotic on Recurrent Urinary Tract Infection in Adult Women
Urinary tract infections (UTIs) are the most common bacterial infections in women, with about 50% of women experiencing at least one UTI in their lifetime.
- Trial name
- NCT03366077
- Testing
- Probiotic
- Where
- Sweden
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Urinary Tract Infections
Fecal Microbiota Transplantation (FMT) for MDRO UTI
The purpose of this study is to determine the safety and impact of fecal microbiota transplantation (FMT) on the fecal and urine microbiome, urine metabolome, risk of recurrent urinary tract infection (UTI), and persistent…
- Trial name
- NCT03367910
- Testing
- Fecal microbiota transplant
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Washington University School of Medicine