Clinical trials: Red Blood Cell Health
Iron Deficiency, Malaria
Acute vs. Delayed Iron: Effect on Red Cell Iron Incorporation in Severe Malaria
The purpose of this study is to determine whether iron therapy given to iron-deficient Ugandan children with moderate-to-severe anemia and clinical malaria is better absorbed and incorporated into red blood cells if it is given…
- Conditions
- Iron Deficiency, Malaria, Nutrition, Global Health
- Trial name
- NCT01754701
- Testing
- Immediate iron, Delayed iron
- Where
- Uganda
- Volunteers
- 100 people
- Sponsor
- University of Minnesota
Systemic Lupus Erythematosus (SLE)
Omega-3 Replacement With Krill Oil in Disease Management of SLE
A randomized, double-blind controlled, multicenter study in SLE patients given AKBM-3031or placebo for 24 weeks (randomized period) and followed by an open label extension (OLE) treatment with AKBM-3031 for the next 24 weeks.
- Trial name
- ORKIDS (NCT03626311)
- Testing
- AKBM-3031
- Where
- 19 sites in United States, Canada
- Volunteers
- 76 people
- Sponsor
- Aker BioMarine Human Ingredients AS
Red Blood Cell Transfusions, Sex Differences
Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes
Red blood cell (RBC) transfusions are selected based upon matching donor and recipient blood group: donor and recipient sex are not considered when selecting blood for transfusion.
- Conditions
- Red Blood Cell Transfusions, Sex Differences, Health Services, Critically Ill Intensive Care Unit Patients
- Trial name
- SexMATTERS RCT (NCT06840756)
- Testing
- Sex-mismatched red blood cell transfusions, Sex-matched red blood cell transfusions
- Where
- 8 sites in Canada
- Volunteers
- 11,082 people
- Sponsor
- Michelle Zeller
Pyruvate Kinase Deficiency, Congenital Non-Spherocytic Hemolytic Anemia
Pyruvate Kinase Deficiency Natural History Study
The purpose of this study is to describe the range and incidence of symptoms, treatments, and complications related to pyruvate kinase deficiency (PKD).
- Trial name
- PKD NHS (NCT02053480)
- Where
- 30 sites in United States, Canada and 4 more
- Volunteers
- 254 people
- Sponsor
- Boston Children's Hospital
Anemia
Well Being of Obstetric Patients on Minimal Blood Transfusions
Postpartum haemorrhage (PPH) is one of the top five causes of maternal mortality in developed and developing countries. The most important treatment of PPH is red blood cell (RBC) transfusion.
- Trial name
- WOMB (NCT00335023)
- Testing
- Red blood cell transfusion
- Where
- Netherlands
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sanquin Research & Blood Bank Divisions
Overweight and Obesity
Active Versus Passive Recovery During HIIT in Children With Overweight or Obesity
This study aims to evaluate the effects of a 12-week high-intensity interval training (HIIT) program with active versus passive recovery on physical performance, anthropometric characteristics, cardiometabolic parameters, and…
- Trial name
- NCT07861048
- Testing
- High-Intensity Interval Training with Active Recovery, High-Intensity Interval Training with Passive Recovery
- Where
- Tunisia
- Volunteers
- 30 people
- Sponsor
- High Institute of Sports and Physical Education of Kef
Red Blood Cell Health, Biological Aging
Effect of Pentadecanoic Acid Supplementation on Red Blood Cell Health and Biological Aging in Healthy Older Adults
This Phase II randomized, double-blind, placebo-controlled, parallel-group study will evaluate the effects of pentadecanoic acid (C15:0) supplementation on red blood cell (RBC) health and predicted biological age in healthy…
- Conditions
- Red Blood Cell Health, Biological Aging, Healthy Aging
- Trial name
- NCT07812792
- Testing
- Pentadecanoic Acid
- Where
- Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- ReCellience15, Inc
Prematurity Complications, Anemia
Personalizing Preterm Neonatal Transfusions With Fetal Hemoglobin-Enriched Cord Blood
Long-term morbidities among very low birth weight infants remain a significant challenge. Oxidative stress is a key factor in the pathogenesis of 'free radical (FR) diseases of prematurity,' including retinopathy of prematurity…
- Trial name
- ANH-Prestige (NCT07636473)
- Testing
- Cord Blood Red Blood Cell Transfusion (CB-RBC), Adult Donor Red Blood Cell Transfusion (A-RBC)
- Volunteers
- 200 people
- Sponsor
- University of Parma
Cognitive Function, Well-Being
Singing Groups for Seniors: Well-Being, Cognitive Function and Health
The researchers' implement and measure the effects of a singing group intervention program for older adults, with an RCT design, in a natural context, on the health, well-being and cognitive function of older adults.
- Conditions
- Cognitive Function, Well-Being, Physical Function, Respiratory Function
- Trial name
- Sing4Health (NCT03985917)
- Testing
- Singing Group Intervention Program, Alternative Social and Leisure Activities
- Where
- Portugal
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Iolanda Costa Galinha
Whole Blood Donation and Leukoreduction
Clinical Investigation to Evaluate the Hemanext® Oxygen Reduction System - Pivotal Trial
The primary goal of Hemanext. is to improve red cell storage through novel storage methods. Based on our review of the pertinent literature, there is substantial evidence suggesting that prolonged exposure to oxygen during…
- Trial name
- NCT03301779
- Testing
- Hemanext Red Blood Cell Processing System
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hemanext